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The map label for this gene is hflX [C]

Identifier: 124028000

GI number: 124028000

Start: 1149615

End: 1150742

Strand: Reverse

Name: hflX [C]

Synonym: Hbut_1138

Alternate gene names: 124028000

Gene position: 1150742-1149615 (Counterclockwise)

Preceding gene: 124028001

Following gene: 124027999

Centisome position: 69.02

GC content: 50.27

Gene sequence:

>1128_bases
ATGGCTAAGGTTGCTGTTTGGAAACCATCAATACTAGTGCTGCCCCGTGGTCTCGCACGATGGGAGGTTAGGGAAGCCTA
TGTGCTAGCTGAAACTGCAGGCTACCGCGTCGTAGATGTCCTCTACTACCGCCGTGTTTCCAGCTCCAAATTGCTAAGCG
ATGCAAAGCTTGAGGAGTTGGCTGAGAAAGCCAAGAGTCTCGTGGGCAACGAGTATGCAAGGATAATAGTCTACGACAAC
CTCAAACCAAGAGAGTATTTTAGGATAGTAAAGGCAACCGGTGTAAACACAATAGATAGGACAATGCTCATTCTCGAAAT
ATTCTCGCTCCACGCTGGTAGCCGCGAAGCAAAGCTCCAAATAGAGCTTGCAAGGCTTAGGCATGAACTGCCTCTGGTCC
GTGAAGCAATCAGACTCTCCAAGCTGAAAGAACTCCCTGGATTTCTAGGCCCTGGCGGCTACGCTATTGATGCATACTAC
CGCTACATGGTTTCCCGCATAGCAAAAATCAAGCGTGAACTGCGAGAACTACGTCGTCGCCACGAGATTGAGAGGAGTAA
GAGGAGGAGCGCAGGCCTACCACACATAGCCATAGTGGGCTACGCGAGTGCCGGTAAGACCTCGCTTTTCAACGCCATAA
CCGGCTTACAGAAACCCGTCGGCCCCGAGTACTTTACAACAATAACACCTAAGAGGAGGGCAATAAGCTTCAATGGACTG
CGAACAGTCTTCATAGATACTGTAGGCTTCATAATGCGTATCCCACCGGAGATAATAGAAGCGTTTCACTCAACACTAGA
GGAAGCTGCTACAGCCGATGTGATACTATATGTTGTGGATGTTTCAGAGCCGGACACAGTTATTGCCGAGAAGCTTGACG
AGGGGCTTCAGACGCTGAGGAGAATAGGTGTAATAGATAAACCCCTAATCATAGCAGCTAACAAGATAGATCTCGTTCCC
CAAGAGGACATCGAGAGGCTCACAAGGCTACTAGAGGGTGCGGCATCAACCCTATACCCCGCCCTGGAAGCTGTGATACC
GGTATCCGCAAAGACGGGTGCTGGGGTGGCTAAGCTGCTATGTCGTATAGCCACCCTGCTAGCAGGTACGAAAGGGTCTA
CGTGTTGA

Upstream 100 bases:

>100_bases
GGGACGAGTTCTACCTAACGTTAGGCGATATAGCCGAAATAAGGGAGGACTAGGCTCCAAGATGTTGTGGAGGTTAGCTT
GCCAGGGTGGGTATTGAGGC

Downstream 100 bases:

>100_bases
GGATAGGTCACAGACCCGAACGAGATAAGAGGATTACTACACATGTAGGGCTTGTAGCTAGAGCTTTTGGCGCTAATGGA
TTCATTTTAGGTGATACATG

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAKVAVWKPSILVLPRGLARWEVREAYVLAETAGYRVVDVLYYRRVSSSKLLSDAKLEELAEKAKSLVGNEYARIIVYDN
LKPREYFRIVKATGVNTIDRTMLILEIFSLHAGSREAKLQIELARLRHELPLVREAIRLSKLKELPGFLGPGGYAIDAYY
RYMVSRIAKIKRELRELRRRHEIERSKRRSAGLPHIAIVGYASAGKTSLFNAITGLQKPVGPEYFTTITPKRRAISFNGL
RTVFIDTVGFIMRIPPEIIEAFHSTLEEAATADVILYVVDVSEPDTVIAEKLDEGLQTLRRIGVIDKPLIIAANKIDLVP
QEDIERLTRLLEGAASTLYPALEAVIPVSAKTGAGVAKLLCRIATLLAGTKGSTC

Sequences:

>Translated_375_residues
MAKVAVWKPSILVLPRGLARWEVREAYVLAETAGYRVVDVLYYRRVSSSKLLSDAKLEELAEKAKSLVGNEYARIIVYDN
LKPREYFRIVKATGVNTIDRTMLILEIFSLHAGSREAKLQIELARLRHELPLVREAIRLSKLKELPGFLGPGGYAIDAYY
RYMVSRIAKIKRELRELRRRHEIERSKRRSAGLPHIAIVGYASAGKTSLFNAITGLQKPVGPEYFTTITPKRRAISFNGL
RTVFIDTVGFIMRIPPEIIEAFHSTLEEAATADVILYVVDVSEPDTVIAEKLDEGLQTLRRIGVIDKPLIIAANKIDLVP
QEDIERLTRLLEGAASTLYPALEAVIPVSAKTGAGVAKLLCRIATLLAGTKGSTC
>Mature_374_residues
AKVAVWKPSILVLPRGLARWEVREAYVLAETAGYRVVDVLYYRRVSSSKLLSDAKLEELAEKAKSLVGNEYARIIVYDNL
KPREYFRIVKATGVNTIDRTMLILEIFSLHAGSREAKLQIELARLRHELPLVREAIRLSKLKELPGFLGPGGYAIDAYYR
YMVSRIAKIKRELRELRRRHEIERSKRRSAGLPHIAIVGYASAGKTSLFNAITGLQKPVGPEYFTTITPKRRAISFNGLR
TVFIDTVGFIMRIPPEIIEAFHSTLEEAATADVILYVVDVSEPDTVIAEKLDEGLQTLRRIGVIDKPLIIAANKIDLVPQ
EDIERLTRLLEGAASTLYPALEAVIPVSAKTGAGVAKLLCRIATLLAGTKGSTC

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=218, Percent_Identity=32.1100917431193, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310124267, Length=218, Percent_Identity=32.1100917431193, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310124171, Length=218, Percent_Identity=32.1100917431193, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310124169, Length=218, Percent_Identity=32.1100917431193, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI310133116, Length=218, Percent_Identity=30.7339449541284, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI310133118, Length=219, Percent_Identity=31.5068493150685, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1790615, Length=354, Percent_Identity=31.638418079096, Blast_Score=154, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17561038, Length=302, Percent_Identity=29.1390728476821, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24650079, Length=240, Percent_Identity=34.1666666666667, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 41778; Mature: 41646

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVAVWKPSILVLPRGLARWEVREAYVLAETAGYRVVDVLYYRRVSSSKLLSDAKLEEL
CCCEEEECCCEEEECCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHH
AEKAKSLVGNEYARIIVYDNLKPREYFRIVKATGVNTIDRTMLILEIFSLHAGSREAKLQ
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHEE
IELARLRHELPLVREAIRLSKLKELPGFLGPGGYAIDAYYRYMVSRIAKIKRELRELRRR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEIERSKRRSAGLPHIAIVGYASAGKTSLFNAITGLQKPVGPEYFTTITPKRRAISFNGL
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHEEECCCH
RTVFIDTVGFIMRIPPEIIEAFHSTLEEAATADVILYVVDVSEPDTVIAEKLDEGLQTLR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
RIGVIDKPLIIAANKIDLVPQEDIERLTRLLEGAASTLYPALEAVIPVSAKTGAGVAKLL
HCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
CRIATLLAGTKGSTC
HHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKVAVWKPSILVLPRGLARWEVREAYVLAETAGYRVVDVLYYRRVSSSKLLSDAKLEEL
CCEEEECCCEEEECCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHH
AEKAKSLVGNEYARIIVYDNLKPREYFRIVKATGVNTIDRTMLILEIFSLHAGSREAKLQ
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHEE
IELARLRHELPLVREAIRLSKLKELPGFLGPGGYAIDAYYRYMVSRIAKIKRELRELRRR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEIERSKRRSAGLPHIAIVGYASAGKTSLFNAITGLQKPVGPEYFTTITPKRRAISFNGL
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEECCCCHHEEECCCH
RTVFIDTVGFIMRIPPEIIEAFHSTLEEAATADVILYVVDVSEPDTVIAEKLDEGLQTLR
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHHHH
RIGVIDKPLIIAANKIDLVPQEDIERLTRLLEGAASTLYPALEAVIPVSAKTGAGVAKLL
HCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
CRIATLLAGTKGSTC
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]