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The map label for this gene is 124027982

Identifier: 124027982

GI number: 124027982

Start: 1132460

End: 1133620

Strand: Reverse

Name: 124027982

Synonym: Hbut_1116

Alternate gene names: NA

Gene position: 1133620-1132460 (Counterclockwise)

Preceding gene: 124027983

Following gene: 124027978

Centisome position: 68.0

GC content: 52.2

Gene sequence:

>1161_bases
ATGAGTAGCTCTACGCTAGCAGAGTTCAGGCCTAGGACAGTTAGGGGTAAGCGCTGGAAGTACAGGATAGAGGACTTTCC
CGAGCCCTACCGGACACTGTACCGGATACTCCAGAAGCAAGGCTACATCATTATAGGCAGGCATAGCGTATACAAGAAGT
GTCACTGGACGCACGCGGCGCTTGTAGAGGAGAGGTTCTGCTATAAGTGCCGGTTCTACGGCATAGAGAGCCACCGTTGC
ATCCAGATGAGCCCATCGGCGCTCTGGTGCTGGAATGCCTGCATGCACTGCTGGAGGCTAAGGCCTACCGACACCATGAG
ATGGGATGACACAAAGATACCGTGGGTTGACGACCCAGATCTAATAGTCGAGGGCAGCATTGAGGCCCACCGAGAAGCCC
TCATGGGCTACCGTGGCCACCCACGAATGGATGAGCGAATGAAGAAGAGGCTCGAGGAAGCAATGAACCCCGCCCATGTA
GCGATAAGTCTGACGGGTGAACCCACACTCTATCCGAGGCTAGGCGAGCTGATAAAGGAGTACCACAAGAGAGGACTAAC
AACGTTCCTCGTAACTCGCGGAATAAGGCCGGATGTTCTCGCTAATCTAGAGGAGGAGCCTACACAGCTCTATGTGAGCC
TCGAGGCCTGGGATAAGAAGAGCTTCAACTACTTCAACAAGCCGCTGGTTCCTAGGGGGTGGGAGTTGACACTCAAGACG
CTAGAGCTACTACCATCATTCTCAAGTATGACTGTTATAAGGTTCACGTTGGTAAAGAGTTTCAACATGCATGATGAAGC
ACTAAAGGCTTGGGCTAAACTCGTAGAGATCTCTCAGCCAACCTACATAGAGTTCAAGTCATACATGCATGTTGGTGCTG
CGCGGCAGAGACTCTCGGCAAGCGATATGGCTAAGCATCTGGAGGTATTCATGTTTGCGAAGAAGTTCGCAGACATGACC
GGATATAGGATAGTATCGCAGCAGATCGAAAGCAGGGTGGTCCTCCTCTCAAGGCTCGACAAGCCCGTCCGTGTCGGCAA
GGGTTGCAAGGAGGGGTGGGAGCGAGAGAAAGTACGCGTAGAGCAGTTGCTCGAACTCCTTGAGCGCAAGAAGGACATAG
ACGAAACTGAATATAGAATGGTACTGGAGCAGAAAATCTAG

Upstream 100 bases:

>100_bases
GTTAATGTAATAGGTAGAGTGACACTAAGTAGGTTATGGGTATTGTTTAAACCTTATTAACTAGCCTATGCTGCTAATCA
CTCCGAGGGCCGGCAGGGTA

Downstream 100 bases:

>100_bases
CCTGAACCCCCCGTTTTAGCTCCACGAAGCCCAAGCCTCTGAATAAGCTCGTAGACCCTCCTAGCCTTCCTCGTATAGAG
CCTCAGCCTACTCCCTCCAG

Product: tRNA-modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSSSTLAEFRPRTVRGKRWKYRIEDFPEPYRTLYRILQKQGYIIIGRHSVYKKCHWTHAALVEERFCYKCRFYGIESHRC
IQMSPSALWCWNACMHCWRLRPTDTMRWDDTKIPWVDDPDLIVEGSIEAHREALMGYRGHPRMDERMKKRLEEAMNPAHV
AISLTGEPTLYPRLGELIKEYHKRGLTTFLVTRGIRPDVLANLEEEPTQLYVSLEAWDKKSFNYFNKPLVPRGWELTLKT
LELLPSFSSMTVIRFTLVKSFNMHDEALKAWAKLVEISQPTYIEFKSYMHVGAARQRLSASDMAKHLEVFMFAKKFADMT
GYRIVSQQIESRVVLLSRLDKPVRVGKGCKEGWEREKVRVEQLLELLERKKDIDETEYRMVLEQKI

Sequences:

>Translated_386_residues
MSSSTLAEFRPRTVRGKRWKYRIEDFPEPYRTLYRILQKQGYIIIGRHSVYKKCHWTHAALVEERFCYKCRFYGIESHRC
IQMSPSALWCWNACMHCWRLRPTDTMRWDDTKIPWVDDPDLIVEGSIEAHREALMGYRGHPRMDERMKKRLEEAMNPAHV
AISLTGEPTLYPRLGELIKEYHKRGLTTFLVTRGIRPDVLANLEEEPTQLYVSLEAWDKKSFNYFNKPLVPRGWELTLKT
LELLPSFSSMTVIRFTLVKSFNMHDEALKAWAKLVEISQPTYIEFKSYMHVGAARQRLSASDMAKHLEVFMFAKKFADMT
GYRIVSQQIESRVVLLSRLDKPVRVGKGCKEGWEREKVRVEQLLELLERKKDIDETEYRMVLEQKI
>Mature_385_residues
SSSTLAEFRPRTVRGKRWKYRIEDFPEPYRTLYRILQKQGYIIIGRHSVYKKCHWTHAALVEERFCYKCRFYGIESHRCI
QMSPSALWCWNACMHCWRLRPTDTMRWDDTKIPWVDDPDLIVEGSIEAHREALMGYRGHPRMDERMKKRLEEAMNPAHVA
ISLTGEPTLYPRLGELIKEYHKRGLTTFLVTRGIRPDVLANLEEEPTQLYVSLEAWDKKSFNYFNKPLVPRGWELTLKTL
ELLPSFSSMTVIRFTLVKSFNMHDEALKAWAKLVEISQPTYIEFKSYMHVGAARQRLSASDMAKHLEVFMFAKKFADMTG
YRIVSQQIESRVVLLSRLDKPVRVGKGCKEGWEREKVRVEQLLELLERKKDIDETEYRMVLEQKI

Specific function: Unknown

COG id: COG0731

COG function: function code C; Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0026 family [H]

Homologues:

Organism=Homo sapiens, GI50726981, Length=311, Percent_Identity=36.6559485530547, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI224282125, Length=279, Percent_Identity=32.9749103942652, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI224282123, Length=265, Percent_Identity=33.2075471698113, Blast_Score=139, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6325049, Length=291, Percent_Identity=35.7388316151203, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197
- InterPro:   IPR013917 [H]

Pfam domain/function: PF04055 Radical_SAM; PF08608 Wyosine_form [H]

EC number: NA

Molecular weight: Translated: 45679; Mature: 45547

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSTLAEFRPRTVRGKRWKYRIEDFPEPYRTLYRILQKQGYIIIGRHSVYKKCHWTHAA
CCCCCCHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
LVEERFCYKCRFYGIESHRCIQMSPSALWCWNACMHCWRLRPTDTMRWDDTKIPWVDDPD
HHHHHHHHHHEEECCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LIVEGSIEAHREALMGYRGHPRMDERMKKRLEEAMNPAHVAISLTGEPTLYPRLGELIKE
EEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
YHKRGLTTFLVTRGIRPDVLANLEEEPTQLYVSLEAWDKKSFNYFNKPLVPRGWELTLKT
HHHCCCCEEHHHCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
LELLPSFSSMTVIRFTLVKSFNMHDEALKAWAKLVEISQPTYIEFKSYMHVGAARQRLSA
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
SDMAKHLEVFMFAKKFADMTGYRIVSQQIESRVVLLSRLDKPVRVGKGCKEGWEREKVRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHH
EQLLELLERKKDIDETEYRMVLEQKI
HHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SSSTLAEFRPRTVRGKRWKYRIEDFPEPYRTLYRILQKQGYIIIGRHSVYKKCHWTHAA
CCCCCHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHH
LVEERFCYKCRFYGIESHRCIQMSPSALWCWNACMHCWRLRPTDTMRWDDTKIPWVDDPD
HHHHHHHHHHEEECCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LIVEGSIEAHREALMGYRGHPRMDERMKKRLEEAMNPAHVAISLTGEPTLYPRLGELIKE
EEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
YHKRGLTTFLVTRGIRPDVLANLEEEPTQLYVSLEAWDKKSFNYFNKPLVPRGWELTLKT
HHHCCCCEEHHHCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHH
LELLPSFSSMTVIRFTLVKSFNMHDEALKAWAKLVEISQPTYIEFKSYMHVGAARQRLSA
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCH
SDMAKHLEVFMFAKKFADMTGYRIVSQQIESRVVLLSRLDKPVRVGKGCKEGWEREKVRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHH
EQLLELLERKKDIDETEYRMVLEQKI
HHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]