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The map label for this gene is yleA [C]

Identifier: 124027960

GI number: 124027960

Start: 1104244

End: 1105569

Strand: Reverse

Name: yleA [C]

Synonym: Hbut_1092

Alternate gene names: 124027960

Gene position: 1105569-1104244 (Counterclockwise)

Preceding gene: 124027961

Following gene: 124027959

Centisome position: 66.31

GC content: 54.07

Gene sequence:

>1326_bases
ATGCAGCGTGGCAGGGTATACATTGAAACCTATGGCTGTGCTTTAAACATGGCTGACACGGCTATTATGCGGAGTGTGTT
GAGTAGCCGTGGCTACAGCTTCACCAATTGTGTTGATGAGGCAGACGTGATTATCATCAATACGTGTACGGTGAGACTGG
ATACAGAAGCCAGGATGAAGAGGAGGATAGCAGAGCTGGCAGCAATAGCCGAGAAAACCGGGGCGAGGCTAGTTGTTGCA
GGATGCATGGCTAGTGCTCAGCCCTATACGGTGAAGCGTATAGCACCGAAAGCAGTGCTAGTCTCAACCTATAATGTGCA
CCTCGTGGACATAGCTGTTGAGAGGGGTCTAGACCTTCTCACCCCTCCGAGGGAGAAGCCGAAGCCGCTCTTCAAGCCAA
CTCCTCGGCTAATGCTTCGCGGGAAAATAGCCGAAGTACCAATAGCAGAGGGCTGCCTCGGGGACTGCAGCTTCTGCATC
ACGAAAATTGCTAGGAGAAGAGTATACAGTAGACCCGTGGAGAATATTGTGAAGCTTGTTCGTGAGCTTGTCCGGCTCGG
AGCCGTCGAGATAAGGCTTACGGGTCAGGATATCGCAGTCTACGGCATAGACCTCTACGGTAAGAGGCTGCTGCCAGAGC
TAGTTCGGCGAGTTATAGAGGTTGAGGGTGACTTCATGGTTCGCATAGGCATGATGAGCCCGGATCAGCTGGAGCCGATA
CTGGACGAGTTCCTGGAGGTGTTCCGCCATCCAAAGGTGTTCAAGTTTGTCCACCTTCCGGTGCAGAGTGGTGACGACCG
AGTTCTAAGGATTATGAAGCGCAACTATACTGTCGACGAATACCGTGCTATCGTGAGGGAGATCCGCAACAAGGTTCCCG
GGGTAATGATAGCTACAGACATTATTGTTGGTCATCCAGGCGAGGATGAGGAAGCGTTTGAAAACACGGTCCGCCTCATA
GAGGAGTTGAGGTTTGAACGTGTCCACCTTGCACAGTATACGCCGCGCCAGCGCACGGTAGCTGCAGGTCTGCCACAAGT
GCCGGATCCCGTGAAGAAGAAGCGGTCTAAGAGGCTCACAGAGGTTGTGATGAGGATTGGGCTCGAGGAGCATCGACGCT
ACATAGGCTCCCGTGCTTGCGCACTGGTTGTCTCACGGGGCGAGCGCGGCGGCCTAGACGCTAAGCTCTACAACTACATG
CCAGTAATACTGCCAGAGGGCTCGGCTAGGCCGGGTGAGTGGAGGTGCATTGAAGTAGTAGACGCAACCTGGTACGACCT
ACGGGGACGCGTGGTTGACTGCACTTGCAAAGGTGGAGGCAGCTAG

Upstream 100 bases:

>100_bases
AGTCCGTGATGGCGACGAGATTGTTATCTTGCCGCCTGCCTCGGGCGGGTAGCAGCTATTAGGGTTTAACACGTGTTTAC
GGCGGTTATCGGGGGGCCTT

Downstream 100 bases:

>100_bases
ACGTGCAGCCGAGATTCTGGAACCCCTCATAGAGAGAGCTGAAAGGATAGGAATTGGTACGGGCTCCACAGTGAGGCTCG
TTCTTAGATTCCTTATCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MQRGRVYIETYGCALNMADTAIMRSVLSSRGYSFTNCVDEADVIIINTCTVRLDTEARMKRRIAELAAIAEKTGARLVVA
GCMASAQPYTVKRIAPKAVLVSTYNVHLVDIAVERGLDLLTPPREKPKPLFKPTPRLMLRGKIAEVPIAEGCLGDCSFCI
TKIARRRVYSRPVENIVKLVRELVRLGAVEIRLTGQDIAVYGIDLYGKRLLPELVRRVIEVEGDFMVRIGMMSPDQLEPI
LDEFLEVFRHPKVFKFVHLPVQSGDDRVLRIMKRNYTVDEYRAIVREIRNKVPGVMIATDIIVGHPGEDEEAFENTVRLI
EELRFERVHLAQYTPRQRTVAAGLPQVPDPVKKKRSKRLTEVVMRIGLEEHRRYIGSRACALVVSRGERGGLDAKLYNYM
PVILPEGSARPGEWRCIEVVDATWYDLRGRVVDCTCKGGGS

Sequences:

>Translated_441_residues
MQRGRVYIETYGCALNMADTAIMRSVLSSRGYSFTNCVDEADVIIINTCTVRLDTEARMKRRIAELAAIAEKTGARLVVA
GCMASAQPYTVKRIAPKAVLVSTYNVHLVDIAVERGLDLLTPPREKPKPLFKPTPRLMLRGKIAEVPIAEGCLGDCSFCI
TKIARRRVYSRPVENIVKLVRELVRLGAVEIRLTGQDIAVYGIDLYGKRLLPELVRRVIEVEGDFMVRIGMMSPDQLEPI
LDEFLEVFRHPKVFKFVHLPVQSGDDRVLRIMKRNYTVDEYRAIVREIRNKVPGVMIATDIIVGHPGEDEEAFENTVRLI
EELRFERVHLAQYTPRQRTVAAGLPQVPDPVKKKRSKRLTEVVMRIGLEEHRRYIGSRACALVVSRGERGGLDAKLYNYM
PVILPEGSARPGEWRCIEVVDATWYDLRGRVVDCTCKGGGS
>Mature_441_residues
MQRGRVYIETYGCALNMADTAIMRSVLSSRGYSFTNCVDEADVIIINTCTVRLDTEARMKRRIAELAAIAEKTGARLVVA
GCMASAQPYTVKRIAPKAVLVSTYNVHLVDIAVERGLDLLTPPREKPKPLFKPTPRLMLRGKIAEVPIAEGCLGDCSFCI
TKIARRRVYSRPVENIVKLVRELVRLGAVEIRLTGQDIAVYGIDLYGKRLLPELVRRVIEVEGDFMVRIGMMSPDQLEPI
LDEFLEVFRHPKVFKFVHLPVQSGDDRVLRIMKRNYTVDEYRAIVREIRNKVPGVMIATDIIVGHPGEDEEAFENTVRLI
EELRFERVHLAQYTPRQRTVAAGLPQVPDPVKKKRSKRLTEVVMRIGLEEHRRYIGSRACALVVSRGERGGLDAKLYNYM
PVILPEGSARPGEWRCIEVVDATWYDLRGRVVDCTCKGGGS

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=446, Percent_Identity=32.5112107623318, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI28872784, Length=497, Percent_Identity=26.7605633802817, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI28872782, Length=502, Percent_Identity=26.2948207171315, Blast_Score=156, Evalue=3e-38,
Organism=Escherichia coli, GI1786882, Length=444, Percent_Identity=30.6306306306306, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1787057, Length=434, Percent_Identity=26.036866359447, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71996771, Length=362, Percent_Identity=30.1104972375691, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553146, Length=477, Percent_Identity=25.7861635220126, Blast_Score=150, Evalue=9e-37,
Organism=Drosophila melanogaster, GI19922432, Length=448, Percent_Identity=31.9196428571429, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI21356207, Length=440, Percent_Identity=30.4545454545455, Blast_Score=170, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006466
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49761; Mature: 49761

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50926 TRAM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRGRVYIETYGCALNMADTAIMRSVLSSRGYSFTNCVDEADVIIINTCTVRLDTEARMK
CCCCEEEEEEECCEECHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEEEECCHHHHH
RRIAELAAIAEKTGARLVVAGCMASAQPYTVKRIAPKAVLVSTYNVHLVDIAVERGLDLL
HHHHHHHHHHHHCCCEEEEEEHHCCCCCCEEHHCCCCEEEEEECCEEEEEEEHHCCCCCC
TPPREKPKPLFKPTPRLMLRGKIAEVPIAEGCLGDCSFCITKIARRRVYSRPVENIVKLV
CCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
RELVRLGAVEIRLTGQDIAVYGIDLYGKRLLPELVRRVIEVEGDFMVRIGMMSPDQLEPI
HHHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
LDEFLEVFRHPKVFKFVHLPVQSGDDRVLRIMKRNYTVDEYRAIVREIRNKVPGVMIATD
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEE
IIVGHPGEDEEAFENTVRLIEELRFERVHLAQYTPRQRTVAAGLPQVPDPVKKKRSKRLT
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHH
EVVMRIGLEEHRRYIGSRACALVVSRGERGGLDAKLYNYMPVILPEGSARPGEWRCIEVV
HHHHHHCHHHHHHHHHHHHHEEEEECCCCCCCCEEHHCCEEEEEECCCCCCCCEEEEEEE
DATWYDLRGRVVDCTCKGGGS
CCCHHHCCCCEEEEEECCCCC
>Mature Secondary Structure
MQRGRVYIETYGCALNMADTAIMRSVLSSRGYSFTNCVDEADVIIINTCTVRLDTEARMK
CCCCEEEEEEECCEECHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEEEECCHHHHH
RRIAELAAIAEKTGARLVVAGCMASAQPYTVKRIAPKAVLVSTYNVHLVDIAVERGLDLL
HHHHHHHHHHHHCCCEEEEEEHHCCCCCCEEHHCCCCEEEEEECCEEEEEEEHHCCCCCC
TPPREKPKPLFKPTPRLMLRGKIAEVPIAEGCLGDCSFCITKIARRRVYSRPVENIVKLV
CCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
RELVRLGAVEIRLTGQDIAVYGIDLYGKRLLPELVRRVIEVEGDFMVRIGMMSPDQLEPI
HHHHHCCCEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH
LDEFLEVFRHPKVFKFVHLPVQSGDDRVLRIMKRNYTVDEYRAIVREIRNKVPGVMIATD
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEE
IIVGHPGEDEEAFENTVRLIEELRFERVHLAQYTPRQRTVAAGLPQVPDPVKKKRSKRLT
EEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHH
EVVMRIGLEEHRRYIGSRACALVVSRGERGGLDAKLYNYMPVILPEGSARPGEWRCIEVV
HHHHHHCHHHHHHHHHHHHHEEEEECCCCCCCCEEHHCCEEEEEECCCCCCCCEEEEEEE
DATWYDLRGRVVDCTCKGGGS
CCCHHHCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]