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The map label for this gene is hypE [C]

Identifier: 124027900

GI number: 124027900

Start: 1043805

End: 1044878

Strand: Reverse

Name: hypE [C]

Synonym: Hbut_1031

Alternate gene names: 124027900

Gene position: 1044878-1043805 (Counterclockwise)

Preceding gene: 124027906

Following gene: 124027899

Centisome position: 62.67

GC content: 55.68

Gene sequence:

>1074_bases
ATGTACTTGGCTAGGGGTAAGAGCTGGCGTGTTCTCTGGAAATTCATAACACTGGCCCATGGTAGTGGTGGACGGGAGAC
TGGAGAGATCGTTGAGAAGCTTATCAGGCCGATGGTGCCCGAGGAGCTGTGGAGGGTTGAGGGTGGCTGGGGCCTCGATG
TCCTGGATGACTCGGCGTTGATACCGTTGCCCGACGGTCGATACTTGGCATTCACAGTTGACTCCTACACTGTCAAACCG
CTATTCTTCCCTGGCGGCGACCTGGGCAAACTTGCTGCTAGCGGTGTTATCAACGACCTACTCATGGCTGGGGCAAAGCC
CCTCGCTGCGGTTGACGCTGTTGTCGTTGAGGAGGGGTTCCCGGTAGAGGATCTGGCGAGGATACTTGAGAGCCTAGCCT
CAACGCTTGCAGCTAACAAGGTTGCACTAATAGGTGGCGATTTCAAGGTGGTTCCAAAGGGTGACCTGGACGGAGTCATA
ATAACAATGGCCGGTGTCGGGGTGGCGGAGAAGCCCATAGTGGATACCAGGATACGGGATGGCGATAAGATAGTGGTATC
TGGCTACCTTGGCGACCATGGTGCTGCAATACTCTCGGTCCGTGAGGGTATCGGGCTTAAGCTAGAGGTTGAGAGCGATG
TTAAACCCCTCACAGACCTAATGATACCACTCATAGAACGGTATGCCGACTACATACACGCTGCTGGCGACCCCACACGG
GGTGGTCTCGCGATGCTACTCAACGACTGGGCTAAGAAGAACGGTCTGGTAATAGCAATCGATGAGGCCAAGATACCTGT
CAGGGAACAGGTTAGAGCTTACGCAGAGCTGCTTGGCGTCGATCCGTTGGCTTTGGCGAGTGAGGGTGCTGCCGTGCTAG
CTGTGGACCCATTAATGGCAGAAGAGGTTGTCGAATTTATGAGGAGTCTCGGGTACGAGGAGGCAACAATCATAGGCGAG
GTCAGGGTGCCAAGGCAGGAGCGCCACCGGGGCCTAGTGATAGCGAAGACTATGGCTGGCGGGTTTAGGATTGTCGAGCC
GCCGAGCGGCGAGCTAGTGCCAAGGATATGCTAG

Upstream 100 bases:

>100_bases
TCAACAGACACAGCATCATCGCATATACTGCTATGCTTCTAATTTTTCTAGCCGTGGTAAAAGTTTTCCGCCCCCGCTGT
CTGGAGATCTATTATGGTGA

Downstream 100 bases:

>100_bases
TTAGGGGAACAAGCGTGGTTCTTTTCAACGCCTACATACTCGCTGGTGGTGAGGGACGCCGCTTCGGCGGGGATAAGCTT
GCAGCGCTCGTGGACAGCGT

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MYLARGKSWRVLWKFITLAHGSGGRETGEIVEKLIRPMVPEELWRVEGGWGLDVLDDSALIPLPDGRYLAFTVDSYTVKP
LFFPGGDLGKLAASGVINDLLMAGAKPLAAVDAVVVEEGFPVEDLARILESLASTLAANKVALIGGDFKVVPKGDLDGVI
ITMAGVGVAEKPIVDTRIRDGDKIVVSGYLGDHGAAILSVREGIGLKLEVESDVKPLTDLMIPLIERYADYIHAAGDPTR
GGLAMLLNDWAKKNGLVIAIDEAKIPVREQVRAYAELLGVDPLALASEGAAVLAVDPLMAEEVVEFMRSLGYEEATIIGE
VRVPRQERHRGLVIAKTMAGGFRIVEPPSGELVPRIC

Sequences:

>Translated_357_residues
MYLARGKSWRVLWKFITLAHGSGGRETGEIVEKLIRPMVPEELWRVEGGWGLDVLDDSALIPLPDGRYLAFTVDSYTVKP
LFFPGGDLGKLAASGVINDLLMAGAKPLAAVDAVVVEEGFPVEDLARILESLASTLAANKVALIGGDFKVVPKGDLDGVI
ITMAGVGVAEKPIVDTRIRDGDKIVVSGYLGDHGAAILSVREGIGLKLEVESDVKPLTDLMIPLIERYADYIHAAGDPTR
GGLAMLLNDWAKKNGLVIAIDEAKIPVREQVRAYAELLGVDPLALASEGAAVLAVDPLMAEEVVEFMRSLGYEEATIIGE
VRVPRQERHRGLVIAKTMAGGFRIVEPPSGELVPRIC
>Mature_357_residues
MYLARGKSWRVLWKFITLAHGSGGRETGEIVEKLIRPMVPEELWRVEGGWGLDVLDDSALIPLPDGRYLAFTVDSYTVKP
LFFPGGDLGKLAASGVINDLLMAGAKPLAAVDAVVVEEGFPVEDLARILESLASTLAANKVALIGGDFKVVPKGDLDGVI
ITMAGVGVAEKPIVDTRIRDGDKIVVSGYLGDHGAAILSVREGIGLKLEVESDVKPLTDLMIPLIERYADYIHAAGDPTR
GGLAMLLNDWAKKNGLVIAIDEAKIPVREQVRAYAELLGVDPLALASEGAAVLAVDPLMAEEVVEFMRSLGYEEATIIGE
VRVPRQERHRGLVIAKTMAGGFRIVEPPSGELVPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=352, Percent_Identity=38.6363636363636, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 38275; Mature: 38275

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLARGKSWRVLWKFITLAHGSGGRETGEIVEKLIRPMVPEELWRVEGGWGLDVLDDSAL
CCCCCCCCHHHHEEEHHHHCCCCCCCHHHHHHHHHHCCCCHHHHEECCCCCCEEECCCCE
IPLPDGRYLAFTVDSYTVKPLFFPGGDLGKLAASGVINDLLMAGAKPLAAVDAVVVEEGF
EECCCCCEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCC
PVEDLARILESLASTLAANKVALIGGDFKVVPKGDLDGVIITMAGVGVAEKPIVDTRIRD
CHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCEEEEEEECCCCCCCCCCCCEECC
GDKIVVSGYLGDHGAAILSVREGIGLKLEVESDVKPLTDLMIPLIERYADYIHAAGDPTR
CCEEEEEEEECCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
GGLAMLLNDWAKKNGLVIAIDEAKIPVREQVRAYAELLGVDPLALASEGAAVLAVDPLMA
CCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEECHHHH
EEVVEFMRSLGYEEATIIGEVRVPRQERHRGLVIAKTMAGGFRIVEPPSGELVPRIC
HHHHHHHHHCCCCCEEEEEEEECCHHHHHCCEEEEEECCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MYLARGKSWRVLWKFITLAHGSGGRETGEIVEKLIRPMVPEELWRVEGGWGLDVLDDSAL
CCCCCCCCHHHHEEEHHHHCCCCCCCHHHHHHHHHHCCCCHHHHEECCCCCCEEECCCCE
IPLPDGRYLAFTVDSYTVKPLFFPGGDLGKLAASGVINDLLMAGAKPLAAVDAVVVEEGF
EECCCCCEEEEEECCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCC
PVEDLARILESLASTLAANKVALIGGDFKVVPKGDLDGVIITMAGVGVAEKPIVDTRIRD
CHHHHHHHHHHHHHHHHHCCEEEEECCEEEEECCCCCEEEEEEECCCCCCCCCCCCEECC
GDKIVVSGYLGDHGAAILSVREGIGLKLEVESDVKPLTDLMIPLIERYADYIHAAGDPTR
CCEEEEEEEECCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
GGLAMLLNDWAKKNGLVIAIDEAKIPVREQVRAYAELLGVDPLALASEGAAVLAVDPLMA
CCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEECHHHH
EEVVEFMRSLGYEEATIIGEVRVPRQERHRGLVIAKTMAGGFRIVEPPSGELVPRIC
HHHHHHHHHCCCCCEEEEEEEECCHHHHHCCEEEEEECCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]