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The map label for this gene is cdc6-1 [H]

Identifier: 124027479

GI number: 124027479

Start: 565873

End: 567096

Strand: Direct

Name: cdc6-1 [H]

Synonym: Hbut_0595

Alternate gene names: 124027479

Gene position: 565873-567096 (Clockwise)

Preceding gene: 124027475

Following gene: 124027481

Centisome position: 33.94

GC content: 56.78

Gene sequence:

>1224_bases
GTGGAGGATATTCTGGAGGAGATATTTGAGCGTGTTGTGAAGTCGCGTATCTTCCGGAACAGGGACATACTGAGCCCCGA
CTATATACCCGATAGGCTGCCCCACCGTGAGAACGAGATACGCAAGGTTGCCAGTGTTCTGGCTCAGGCGTTGAAGGGTA
GTAAGCCCAGCAACCTATTCATCTACGGGCTCACGGGGACGGGGAAGACAGCGGTAACCCTCTACGTGTTGCGGAGGCTT
GAGGCTAAGGCTAGGCAGCTTGGTGTTCCCGTGAGATTCTCCTACGTGAACACCAGGCAGAGGGATACACCGTACAAGGT
GCTGGCGGACATAGCCTCCTCGATAGGCGTCCGTGTCCCGTTCACCGGGCTTTCAACTGCAGAGGTCTACGCTAGGATTG
TCCGGGGATTGTCGAGGATGCAGGGTGTGCTCATCGTTGTGCTTGACGAGGTTGACTGGCTTGTCCGCCGTAGGGGCGAC
GACCTACTATACAAGCTGACGAGGATAGGCTATGAGTTGCCGCCTGGGGCCGCGAAGGTCTCAATAGTCGGGATAACGAA
CGATGTCCGGTTCGTAGAGTTGCTCGATGCACGTGTCCGGAGTAGCCTCGGGGAGGAGGAGATAGTGTTCCCGCCCTATA
ACGCTGAGCAGCTACGTGACATACTGTGGGAGAGAGCTAGGGAGGCCTTTCAGCCGGGCGCCGTAGACGACTCCGTGATA
TCCTACTGCGCAGCGCTGGCAGCTAGGGAGCATGGTGATGCACGCCGGGCCCTGGACCTCTTGAGGGTTGCGGGTGAGGT
TGCTGAGAGGGAGAATGCCGATAAAGTCACCATTGAGCATGTAAAGAAGGCTTGGAGCCAGCTTGAGAGGGATAGAGTGT
TAGAGGTTGTCTCGACGCTGCCACTCCATGCCCGTCTAGTGCTCCTAGCTGCCATTGCGAGCGGTGCTGCGAACGGGTAC
ACTACTACCGGCGAGCTATACGCGGCCTACCGGGAGCTGGCTTCAGCCGTGGGAGTGGAGAGCGTTACACAGCGGAGAGT
TAGCGATATCATCAACGAGCTGGATATGCTAGGCATTCTCTCGGCAAGGGTTGTAAGCAGAGGCCGCTACGGCAAGACAA
GAATCATAACGCTTGCGGCTGACCGTGACACTGTACTGGAGGCGTTGAGGAGGGATTCAAGGCTTAGCGAGCTGGTTGAA
AACTTACAAAACCCTAGAGGTTAG

Upstream 100 bases:

>100_bases
CGTGGGGCTTTGTCCCTGTGAGGCTTGCCCAGAGGTCTTGCCCCCTCTGGGTTTTATGCCGTATCTTCCAGCACTTGAAG
CATGCGTATTGGGGGTTCTG

Downstream 100 bases:

>100_bases
TGTGTAAGCCTCTGCAGCGCCTCCCCAAGGAGTGTCAGGCTCGGTATAGCTGCTAGCCTGGCCTCGGGCATGTAGACTGG
CTCCCTGAGGCTCCGGTTAA

Product: Cdc6-1

Products: NA

Alternate protein names: CDC6 homolog 1 [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MEDILEEIFERVVKSRIFRNRDILSPDYIPDRLPHRENEIRKVASVLAQALKGSKPSNLFIYGLTGTGKTAVTLYVLRRL
EAKARQLGVPVRFSYVNTRQRDTPYKVLADIASSIGVRVPFTGLSTAEVYARIVRGLSRMQGVLIVVLDEVDWLVRRRGD
DLLYKLTRIGYELPPGAAKVSIVGITNDVRFVELLDARVRSSLGEEEIVFPPYNAEQLRDILWERAREAFQPGAVDDSVI
SYCAALAAREHGDARRALDLLRVAGEVAERENADKVTIEHVKKAWSQLERDRVLEVVSTLPLHARLVLLAAIASGAANGY
TTTGELYAAYRELASAVGVESVTQRRVSDIINELDMLGILSARVVSRGRYGKTRIITLAADRDTVLEALRRDSRLSELVE
NLQNPRG

Sequences:

>Translated_407_residues
MEDILEEIFERVVKSRIFRNRDILSPDYIPDRLPHRENEIRKVASVLAQALKGSKPSNLFIYGLTGTGKTAVTLYVLRRL
EAKARQLGVPVRFSYVNTRQRDTPYKVLADIASSIGVRVPFTGLSTAEVYARIVRGLSRMQGVLIVVLDEVDWLVRRRGD
DLLYKLTRIGYELPPGAAKVSIVGITNDVRFVELLDARVRSSLGEEEIVFPPYNAEQLRDILWERAREAFQPGAVDDSVI
SYCAALAAREHGDARRALDLLRVAGEVAERENADKVTIEHVKKAWSQLERDRVLEVVSTLPLHARLVLLAAIASGAANGY
TTTGELYAAYRELASAVGVESVTQRRVSDIINELDMLGILSARVVSRGRYGKTRIITLAADRDTVLEALRRDSRLSELVE
NLQNPRG
>Mature_407_residues
MEDILEEIFERVVKSRIFRNRDILSPDYIPDRLPHRENEIRKVASVLAQALKGSKPSNLFIYGLTGTGKTAVTLYVLRRL
EAKARQLGVPVRFSYVNTRQRDTPYKVLADIASSIGVRVPFTGLSTAEVYARIVRGLSRMQGVLIVVLDEVDWLVRRRGD
DLLYKLTRIGYELPPGAAKVSIVGITNDVRFVELLDARVRSSLGEEEIVFPPYNAEQLRDILWERAREAFQPGAVDDSVI
SYCAALAAREHGDARRALDLLRVAGEVAERENADKVTIEHVKKAWSQLERDRVLEVVSTLPLHARLVLLAAIASGAANGY
TTTGELYAAYRELASAVGVESVTQRRVSDIINELDMLGILSARVVSRGRYGKTRIITLAADRDTVLEALRRDSRLSELVE
NLQNPRG

Specific function: Might be involved in the initiation of DNA replication [H]

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family [H]

Homologues:

Organism=Homo sapiens, GI4502703, Length=378, Percent_Identity=24.3386243386243, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI299890795, Length=376, Percent_Identity=27.1276595744681, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI299890793, Length=376, Percent_Identity=27.1276595744681, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI31795544, Length=376, Percent_Identity=27.1276595744681, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555708, Length=294, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17506005, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137456, Length=339, Percent_Identity=29.2035398230088, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21355681, Length=398, Percent_Identity=23.8693467336683, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR002182
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09079 Cdc6_C; PF00931 NB-ARC [H]

EC number: NA

Molecular weight: Translated: 45473; Mature: 45473

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDILEEIFERVVKSRIFRNRDILSPDYIPDRLPHRENEIRKVASVLAQALKGSKPSNLF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEE
IYGLTGTGKTAVTLYVLRRLEAKARQLGVPVRFSYVNTRQRDTPYKVLADIASSIGVRVP
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
FTGLSTAEVYARIVRGLSRMQGVLIVVLDEVDWLVRRRGDDLLYKLTRIGYELPPGAAKV
CCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEE
SIVGITNDVRFVELLDARVRSSLGEEEIVFPPYNAEQLRDILWERAREAFQPGAVDDSVI
EEEEECCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
SYCAALAAREHGDARRALDLLRVAGEVAERENADKVTIEHVKKAWSQLERDRVLEVVSTL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PLHARLVLLAAIASGAANGYTTTGELYAAYRELASAVGVESVTQRRVSDIINELDMLGIL
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SARVVSRGRYGKTRIITLAADRDTVLEALRRDSRLSELVENLQNPRG
HHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEDILEEIFERVVKSRIFRNRDILSPDYIPDRLPHRENEIRKVASVLAQALKGSKPSNLF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEE
IYGLTGTGKTAVTLYVLRRLEAKARQLGVPVRFSYVNTRQRDTPYKVLADIASSIGVRVP
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCC
FTGLSTAEVYARIVRGLSRMQGVLIVVLDEVDWLVRRRGDDLLYKLTRIGYELPPGAAKV
CCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEE
SIVGITNDVRFVELLDARVRSSLGEEEIVFPPYNAEQLRDILWERAREAFQPGAVDDSVI
EEEEECCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHH
SYCAALAAREHGDARRALDLLRVAGEVAERENADKVTIEHVKKAWSQLERDRVLEVVSTL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
PLHARLVLLAAIASGAANGYTTTGELYAAYRELASAVGVESVTQRRVSDIINELDMLGIL
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SARVVSRGRYGKTRIITLAADRDTVLEALRRDSRLSELVENLQNPRG
HHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]