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The map label for this gene is 124027455

Identifier: 124027455

GI number: 124027455

Start: 542242

End: 542961

Strand: Direct

Name: 124027455

Synonym: Hbut_0570

Alternate gene names: NA

Gene position: 542242-542961 (Clockwise)

Preceding gene: 124027454

Following gene: 124027456

Centisome position: 32.52

GC content: 50.83

Gene sequence:

>720_bases
TTGGCCAGGATATATGTGCAGAATAGGAGCATAGTTGTGCCGGGGGATCTCCTGGCTGAGGGCGAGGATGTGGTAGTGGA
GTCCATCTTTGTTGAGCGTGTAGGTCTAAAGTACTACGCTACTATAACTGGGCTTGCCAATGTACAGCAGGAGGATGGCA
AGTTCAAGGTATCCATTATACCACTCGAGGGAGCCTACATACCCCGCCCAGGCGACATAGTTATAGGGCTTGTAAGGGAT
ATAGGGCTCACTCATTGGGAGGTAGACATCGCCTCGCCCTACAAGGGCATACTCACTGTGCAGGAGGTACTAGATCGCCC
CTTTAACCCCGCAACCGATAGCCTGAAGAAGTACCTCGATGTAGGCGACTACATTGTCGCCAAGATAGTAGCTTTTGACC
GCGCAAGGGATCCATTACTAACAATCAAGGGTAAGGGGCTCGGCCGCATAGTCGAGGGCTCCATTGTCGAGATTAAGCCC
AGCCGTGTACCCAGGGTTATAGGTAAGAAGGGCTCAATGGTGAACATGATTATGCAGGAGACTGGCTGCGAGGTACTCGT
GGGCCAGAATGGGAGGATACTAGTTAAATGCCCTAATCGGGAGCTTGAAGAGATAGTAGTACTCTCAATAAAGAAGATTG
AAGCCGAGGCTCATACAACGGGGCTCACTGAAAGGGTTAGGGAGTTCATTAGGAGGGAGAGGAGTAGGAGAGGTGTATAA

Upstream 100 bases:

>100_bases
GAGATACCCGCGGGGCTTCAGCAGGAGGTTATAGACAAGCTTAACAAGCTCACGCAAGGCAATGTGGATGTTAAGATTGT
GAGCGTGGTGTAGCAGGGCC

Downstream 100 bases:

>100_bases
CCCATGGCTGGCGGTGCCGGTGAGAAACCCACCCTTATAAGGTGGGAGGAGCGGGACGGCCAGAAAGTAGCTATCCGCCA
TGATGGTAGGCTGCCGGAGC

Product: exosome complex RNA-binding protein Rrp4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MARIYVQNRSIVVPGDLLAEGEDVVVESIFVERVGLKYYATITGLANVQQEDGKFKVSIIPLEGAYIPRPGDIVIGLVRD
IGLTHWEVDIASPYKGILTVQEVLDRPFNPATDSLKKYLDVGDYIVAKIVAFDRARDPLLTIKGKGLGRIVEGSIVEIKP
SRVPRVIGKKGSMVNMIMQETGCEVLVGQNGRILVKCPNRELEEIVVLSIKKIEAEAHTTGLTERVREFIRRERSRRGV

Sequences:

>Translated_239_residues
MARIYVQNRSIVVPGDLLAEGEDVVVESIFVERVGLKYYATITGLANVQQEDGKFKVSIIPLEGAYIPRPGDIVIGLVRD
IGLTHWEVDIASPYKGILTVQEVLDRPFNPATDSLKKYLDVGDYIVAKIVAFDRARDPLLTIKGKGLGRIVEGSIVEIKP
SRVPRVIGKKGSMVNMIMQETGCEVLVGQNGRILVKCPNRELEEIVVLSIKKIEAEAHTTGLTERVREFIRRERSRRGV
>Mature_238_residues
ARIYVQNRSIVVPGDLLAEGEDVVVESIFVERVGLKYYATITGLANVQQEDGKFKVSIIPLEGAYIPRPGDIVIGLVRDI
GLTHWEVDIASPYKGILTVQEVLDRPFNPATDSLKKYLDVGDYIVAKIVAFDRARDPLLTIKGKGLGRIVEGSIVEIKPS
RVPRVIGKKGSMVNMIMQETGCEVLVGQNGRILVKCPNRELEEIVVLSIKKIEAEAHTTGLTERVREFIRRERSRRGV

Specific function: Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome (Potential) [H]

COG id: COG1097

COG function: function code J; RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR018111
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967 [H]

Pfam domain/function: PF00013 KH_1; PF00575 S1 [H]

EC number: NA

Molecular weight: Translated: 26562; Mature: 26431

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50084 KH_TYPE_1 ; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIYVQNRSIVVPGDLLAEGEDVVVESIFVERVGLKYYATITGLANVQQEDGKFKVSII
CEEEEEECCCEEECCHHHHCCCHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCEEEEEEE
PLEGAYIPRPGDIVIGLVRDIGLTHWEVDIASPYKGILTVQEVLDRPFNPATDSLKKYLD
EECCCCCCCCCCEEEEEHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHC
VGDYIVAKIVAFDRARDPLLTIKGKGLGRIVEGSIVEIKPSRVPRVIGKKGSMVNMIMQE
CCHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCEEEECCCCCCHHHCCCCCHHHHHHHH
TGCEVLVGQNGRILVKCPNRELEEIVVLSIKKIEAEAHTTGLTERVREFIRRERSRRGV
CCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARIYVQNRSIVVPGDLLAEGEDVVVESIFVERVGLKYYATITGLANVQQEDGKFKVSII
EEEEEECCCEEECCHHHHCCCHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCEEEEEEE
PLEGAYIPRPGDIVIGLVRDIGLTHWEVDIASPYKGILTVQEVLDRPFNPATDSLKKYLD
EECCCCCCCCCCEEEEEHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHC
VGDYIVAKIVAFDRARDPLLTIKGKGLGRIVEGSIVEIKPSRVPRVIGKKGSMVNMIMQE
CCHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCEEEECCCCCCHHHCCCCCHHHHHHHH
TGCEVLVGQNGRILVKCPNRELEEIVVLSIKKIEAEAHTTGLTERVREFIRRERSRRGV
CCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]