Click here to switch to the map view.

The map label for this gene is ribH [H]

Identifier: 124027445

GI number: 124027445

Start: 534432

End: 534896

Strand: Direct

Name: ribH [H]

Synonym: Hbut_0560

Alternate gene names: 124027445

Gene position: 534432-534896 (Clockwise)

Preceding gene: 124027444

Following gene: 124027446

Centisome position: 32.06

GC content: 52.9

Gene sequence:

>465_bases
GTGTCTGCAGCTGATGTGAGGCTTGCATTTGTTGTAGCGGAATTCAACTATGACGTGACCTACCTCATGCTCCAGCGTGC
GCTGAGCTATGCCAGGTTCCGTGGTGCAACTGTAACGTACATTGTTTACTCTCCCGGAGCCTACGATATGCCGATACTGG
TAGAGGAGTTGCTGATAAAGGATGATGTGGATGCTGTGGTTGCGCTGGGTGCAATAATAACCGGGGCTACAAAGCACGAC
GAGGTGATAGCACACCAAGTAGCTAGGAAGCTAATGGACCTCGCTGAGAAGCATGGTAAGCCCGTAACTCTAGGCATATC
TGGCCCGGGCATGAACCGTGTGCAGGCCCTGGAGCGCGTGGACGACTATGCTAGGAGAGCTGTTGAGGCAGCAGTAAAGC
TGGCCAAGAGGCTGAAAATGCTTAGGGAGGCAAGGTTTGAAGGTGAGACAGTCACGATCCAGTAG

Upstream 100 bases:

>100_bases
GGCTATCCTGATGCAGGCCCTATAATGGGCGGGTATGGCTAGCCAAGCATTTTTCCCCGCCAAGGCCTAAGGCTCACTGG
GCTACGGGGTGTAGAGAGCA

Downstream 100 bases:

>100_bases
AGGCTTCTGCATCTGTGCAGACTACGTAGTTGCCGGTAGCGAGCTCGAGCTGCTGCGGGCCGCCTGCATAGAATTCAACG
AGGAAGGCATAGTCGTCGGT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSAADVRLAFVVAEFNYDVTYLMLQRALSYARFRGATVTYIVYSPGAYDMPILVEELLIKDDVDAVVALGAIITGATKHD
EVIAHQVARKLMDLAEKHGKPVTLGISGPGMNRVQALERVDDYARRAVEAAVKLAKRLKMLREARFEGETVTIQ

Sequences:

>Translated_154_residues
MSAADVRLAFVVAEFNYDVTYLMLQRALSYARFRGATVTYIVYSPGAYDMPILVEELLIKDDVDAVVALGAIITGATKHD
EVIAHQVARKLMDLAEKHGKPVTLGISGPGMNRVQALERVDDYARRAVEAAVKLAKRLKMLREARFEGETVTIQ
>Mature_153_residues
SAADVRLAFVVAEFNYDVTYLMLQRALSYARFRGATVTYIVYSPGAYDMPILVEELLIKDDVDAVVALGAIITGATKHDE
VIAHQVARKLMDLAEKHGKPVTLGISGPGMNRVQALERVDDYARRAVEAAVKLAKRLKMLREARFEGETVTIQ

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 17040; Mature: 16909

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAADVRLAFVVAEFNYDVTYLMLQRALSYARFRGATVTYIVYSPGAYDMPILVEELLIK
CCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
DDVDAVVALGAIITGATKHDEVIAHQVARKLMDLAEKHGKPVTLGISGPGMNRVQALERV
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
DDYARRAVEAAVKLAKRLKMLREARFEGETVTIQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
SAADVRLAFVVAEFNYDVTYLMLQRALSYARFRGATVTYIVYSPGAYDMPILVEELLIK
CCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHH
DDVDAVVALGAIITGATKHDEVIAHQVARKLMDLAEKHGKPVTLGISGPGMNRVQALERV
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHH
DDYARRAVEAAVKLAKRLKMLREARFEGETVTIQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA