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The map label for this gene is rtcB [C]

Identifier: 124027405

GI number: 124027405

Start: 501274

End: 502728

Strand: Direct

Name: rtcB [C]

Synonym: Hbut_0518

Alternate gene names: 124027405

Gene position: 501274-502728 (Clockwise)

Preceding gene: 124027404

Following gene: 124027406

Centisome position: 30.07

GC content: 55.26

Gene sequence:

>1455_bases
TTGAGCGCCAGGATTCCACTCCGTAAAATCAGCGAGTTCGAATGGGAAATACCCAAGGGCGCTAAGCCCTGCATGAAGGT
CCCATCCATAATCTTTGCAGACGAGTTTCTGCTCGAAAAAATGAAGGGTGACCTAACACTGGTCCAGGCAGCCAATGTGG
CATGTCTCGGCGGCATACAGAAGTACAGCATTGTGATGCCCGACGGACACCAGGGCTACGGTTTCCCCATAGGCGGCGTA
GCAGCCATGGCCGTTGACGAGGACGGTGTCATAAGCCCTGGCGGCGTGGGCTACGACATCAACTGTGGTGTACGCCTCAT
AAGGACTAACCTAGACATAAAGGATGTCAAGCCTAAGCTACGCGAGCTAATAGACGAGCTATTCCGCAACATACCAAGCG
GCCTTGGTAGTAGCGGCAAGATCAGGCTGAGCATCCAGGAGCTAAACAAGGTGCTAGATGAGGGTGTCGAGTGGGCCGTA
CAGAGGGGCTACGGCTGGGCTGAGGACCCAGACCACATAGAGGAGAGGGGTAGCTGGACAGCTGCAGACTCCAGCAAGGT
TAGCGACCGTGCCAAGAGGCGGGGCGCAGAGCAACTAGGTACGCTCGGCAGCGGCAACCACTTCCTAGAGGTGCAAGTGG
TAGACAAGATCTACGACCCGAAGCTAGCCGAAGCCATGGGCATAACTCATGAAGGCCAGGTAATGGTGATGGTCCACACA
GGCAGCAGAGGCCTGGGTCACCAGGTCGCGAGCGACTACCTAATGATAATGGAGCGCGCCATGAGAAAGTATGGTATAAG
GCCGCCAGACCGTGAGCTGGCAAGCGTACCATTCAACAGCAGGGAGGGTCAAGACTACTTCAAGGCAATGGCTGCAGCGG
CCAACTTTGCCTGGACAAACAGGCAGCTAATCACCTACTGGGCCAGGGAGAGCTTCAAGAAGGTCTTCCACCGCGACCCC
GACCAGCTAGACATGGTTATAGTCTACGACGTAGCCCACAACATAGCCAAGCTAGAAGAACACGACGTAGACGGCAAGAG
GAAGCAGCTAATAGTACACCGTAAAGGCGCCACTCGTGCCTTCCCACCGGGACACCCACAGATACCCAAGGACTACCAGG
CCATAGGCCAGCCAGTACTCATTCCGGGCAGCATGGGTACAGCAAGCTACGTACTGGTAGGCGTCCCAACAGGTGCAAGG
GCATGGTACACAGCGCCACACGGAGCTGGCAGATGGCTGAGCAGAGCAGCAGCTAAGAGAATGAAGAGCTACACCCAAGT
AGTAAGAGAGCTAGAAGCTAAAGGTATACTCATAAGGGCAAGTGATCGTGCCACCGTAGTTGAGGAAATGCCGCAGGCAT
ACAAGGACGTAGATAGGGTAGCCCTAGTGGCACATCGCGTAGGCATAGCCAAGATGGTAGTCAGACTACGTCCACTAGCA
GTAACGAAGGGTTAG

Upstream 100 bases:

>100_bases
AACCCGAAACAGCTTCGGAGTCCTTTGGGTTGTGTGAAGTTATAACCCTTTAGATGCTCCAAGCTTACAATCGGGCACGC
CGCATAGAGGGTGTCCGGGC

Downstream 100 bases:

>100_bases
CCTCTCCACACTACCCGAAAACCCCACCAAAACATACTCCCGGTACTACTGATGCATACTAGAAGAGCTAGACTGTAGGA
CTCTAATGCTCACTCCACGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSARIPLRKISEFEWEIPKGAKPCMKVPSIIFADEFLLEKMKGDLTLVQAANVACLGGIQKYSIVMPDGHQGYGFPIGGV
AAMAVDEDGVISPGGVGYDINCGVRLIRTNLDIKDVKPKLRELIDELFRNIPSGLGSSGKIRLSIQELNKVLDEGVEWAV
QRGYGWAEDPDHIEERGSWTAADSSKVSDRAKRRGAEQLGTLGSGNHFLEVQVVDKIYDPKLAEAMGITHEGQVMVMVHT
GSRGLGHQVASDYLMIMERAMRKYGIRPPDRELASVPFNSREGQDYFKAMAAAANFAWTNRQLITYWARESFKKVFHRDP
DQLDMVIVYDVAHNIAKLEEHDVDGKRKQLIVHRKGATRAFPPGHPQIPKDYQAIGQPVLIPGSMGTASYVLVGVPTGAR
AWYTAPHGAGRWLSRAAAKRMKSYTQVVRELEAKGILIRASDRATVVEEMPQAYKDVDRVALVAHRVGIAKMVVRLRPLA
VTKG

Sequences:

>Translated_484_residues
MSARIPLRKISEFEWEIPKGAKPCMKVPSIIFADEFLLEKMKGDLTLVQAANVACLGGIQKYSIVMPDGHQGYGFPIGGV
AAMAVDEDGVISPGGVGYDINCGVRLIRTNLDIKDVKPKLRELIDELFRNIPSGLGSSGKIRLSIQELNKVLDEGVEWAV
QRGYGWAEDPDHIEERGSWTAADSSKVSDRAKRRGAEQLGTLGSGNHFLEVQVVDKIYDPKLAEAMGITHEGQVMVMVHT
GSRGLGHQVASDYLMIMERAMRKYGIRPPDRELASVPFNSREGQDYFKAMAAAANFAWTNRQLITYWARESFKKVFHRDP
DQLDMVIVYDVAHNIAKLEEHDVDGKRKQLIVHRKGATRAFPPGHPQIPKDYQAIGQPVLIPGSMGTASYVLVGVPTGAR
AWYTAPHGAGRWLSRAAAKRMKSYTQVVRELEAKGILIRASDRATVVEEMPQAYKDVDRVALVAHRVGIAKMVVRLRPLA
VTKG
>Mature_483_residues
SARIPLRKISEFEWEIPKGAKPCMKVPSIIFADEFLLEKMKGDLTLVQAANVACLGGIQKYSIVMPDGHQGYGFPIGGVA
AMAVDEDGVISPGGVGYDINCGVRLIRTNLDIKDVKPKLRELIDELFRNIPSGLGSSGKIRLSIQELNKVLDEGVEWAVQ
RGYGWAEDPDHIEERGSWTAADSSKVSDRAKRRGAEQLGTLGSGNHFLEVQVVDKIYDPKLAEAMGITHEGQVMVMVHTG
SRGLGHQVASDYLMIMERAMRKYGIRPPDRELASVPFNSREGQDYFKAMAAAANFAWTNRQLITYWARESFKKVFHRDPD
QLDMVIVYDVAHNIAKLEEHDVDGKRKQLIVHRKGATRAFPPGHPQIPKDYQAIGQPVLIPGSMGTASYVLVGVPTGARA
WYTAPHGAGRWLSRAAAKRMKSYTQVVRELEAKGILIRASDRATVVEEMPQAYKDVDRVALVAHRVGIAKMVVRLRPLAV
TKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=494, Percent_Identity=50.2024291497976, Blast_Score=489, Evalue=1e-138,
Organism=Escherichia coli, GI2367224, Length=440, Percent_Identity=28.8636363636364, Blast_Score=154, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17506665, Length=494, Percent_Identity=50.8097165991903, Blast_Score=484, Evalue=1e-137,
Organism=Drosophila melanogaster, GI24585217, Length=494, Percent_Identity=51.0121457489879, Blast_Score=477, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 53516; Mature: 53385

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARIPLRKISEFEWEIPKGAKPCMKVPSIIFADEFLLEKMKGDLTLVQAANVACLGGIQ
CCCCCCHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCC
KYSIVMPDGHQGYGFPIGGVAAMAVDEDGVISPGGVGYDINCGVRLIRTNLDIKDVKPKL
EEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCEEEEEECCCHHHCCHHH
RELIDELFRNIPSGLGSSGKIRLSIQELNKVLDEGVEWAVQRGYGWAEDPDHIEERGSWT
HHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
AADSSKVSDRAKRRGAEQLGTLGSGNHFLEVQVVDKIYDPKLAEAMGITHEGQVMVMVHT
CCCCHHHHHHHHHCCHHHHCCCCCCCEEEEEEEECHHCCCHHHHHHCCCCCCEEEEEEEC
GSRGLGHQVASDYLMIMERAMRKYGIRPPDRELASVPFNSREGQDYFKAMAAAANFAWTN
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
RQLITYWARESFKKVFHRDPDQLDMVIVYDVAHNIAKLEEHDVDGKRKQLIVHRKGATRA
CHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHEEEEEECCCCCC
FPPGHPQIPKDYQAIGQPVLIPGSMGTASYVLVGVPTGARAWYTAPHGAGRWLSRAAAKR
CCCCCCCCCHHHHHCCCCEEEECCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
MKSYTQVVRELEAKGILIRASDRATVVEEMPQAYKDVDRVALVAHRVGIAKMVVRLRPLA
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VTKG
ECCC
>Mature Secondary Structure 
SARIPLRKISEFEWEIPKGAKPCMKVPSIIFADEFLLEKMKGDLTLVQAANVACLGGIQ
CCCCCHHHHCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCC
KYSIVMPDGHQGYGFPIGGVAAMAVDEDGVISPGGVGYDINCGVRLIRTNLDIKDVKPKL
EEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCEEEEEECCCHHHCCHHH
RELIDELFRNIPSGLGSSGKIRLSIQELNKVLDEGVEWAVQRGYGWAEDPDHIEERGSWT
HHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCC
AADSSKVSDRAKRRGAEQLGTLGSGNHFLEVQVVDKIYDPKLAEAMGITHEGQVMVMVHT
CCCCHHHHHHHHHCCHHHHCCCCCCCEEEEEEEECHHCCCHHHHHHCCCCCCEEEEEEEC
GSRGLGHQVASDYLMIMERAMRKYGIRPPDRELASVPFNSREGQDYFKAMAAAANFAWTN
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
RQLITYWARESFKKVFHRDPDQLDMVIVYDVAHNIAKLEEHDVDGKRKQLIVHRKGATRA
CHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHEEEEEECCCCCC
FPPGHPQIPKDYQAIGQPVLIPGSMGTASYVLVGVPTGARAWYTAPHGAGRWLSRAAAKR
CCCCCCCCCHHHHHCCCCEEEECCCCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
MKSYTQVVRELEAKGILIRASDRATVVEEMPQAYKDVDRVALVAHRVGIAKMVVRLRPLA
HHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
VTKG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]