Click here to switch to the map view.

The map label for this gene is gpt [H]

Identifier: 124027370

GI number: 124027370

Start: 460123

End: 460743

Strand: Direct

Name: gpt [H]

Synonym: Hbut_0483

Alternate gene names: 124027370

Gene position: 460123-460743 (Clockwise)

Preceding gene: 124027369

Following gene: 124027371

Centisome position: 27.6

GC content: 48.79

Gene sequence:

>621_bases
TTGACGGGTATACCACATCCACAGCCGACGAGGTTTAAGCCTGTATCATGGCGTGAAGTTGAGGAGGGCTGCGCCCACAT
AGCCGAGAAGATTCTCGCTACGAACCTTAATGTAGATGTGATCGTCGGCATCCTGCGGGGCGGCTGGATACCGGCAAGAC
TCCTCTCTGACTACCTAGGCGTAGACACTATGGGCGCACTCGAGGTAAAGTTCTACCGGGGTGTTGGCGAGACAGCAGAG
AAACCTGTTATAACACAGCCGCTCATAGTGAATGTTAGGGATAAGGTTGTACTTGTAGTTGACGATGTCTCCGATACCGG
TAAGACGCTTACCGTGGCAGTGAACTTCCTAATGCACTATGGCCCGAGAAAGATAGTAACTGCTACACTCTATGTTAAAC
CGTGGTCCATGTATAGGCCAGACTTCTACCACAGCGAGACTGATGCATGGATAATATTCCCCTGGGATAAGGCTGAAACT
GTTGTAGAGCTTGTAGCAAAACGTGGACTCAGCATAGAAGAGGTCTCAAAAATTACGGGTGAAAGCATTGACTTCATTAG
AAGAATCTTTGAGACAAGGAATAAGGCTTCAACAACTAGTTCCAGGGCTGGGCAGGATTAG

Upstream 100 bases:

>100_bases
GTATTTGCACTTCTTAGGCCCTTGTTTGCTACACATTGCAATATAATGACTGATAGAATTACCTCTTAGCCTAGCATGTA
TGTGAGGTGGCATGGAGGGT

Downstream 100 bases:

>100_bases
CCTCCTACTACTCTGCACGAGGACAGATGAGGAGCTAGAGAAGCTTGCAGACAGCCTTGAAGCTGATCGCAAATGTATAG
TGGGCATTATACCCGTATCG

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MTGIPHPQPTRFKPVSWREVEEGCAHIAEKILATNLNVDVIVGILRGGWIPARLLSDYLGVDTMGALEVKFYRGVGETAE
KPVITQPLIVNVRDKVVLVVDDVSDTGKTLTVAVNFLMHYGPRKIVTATLYVKPWSMYRPDFYHSETDAWIIFPWDKAET
VVELVAKRGLSIEEVSKITGESIDFIRRIFETRNKASTTSSRAGQD

Sequences:

>Translated_206_residues
MTGIPHPQPTRFKPVSWREVEEGCAHIAEKILATNLNVDVIVGILRGGWIPARLLSDYLGVDTMGALEVKFYRGVGETAE
KPVITQPLIVNVRDKVVLVVDDVSDTGKTLTVAVNFLMHYGPRKIVTATLYVKPWSMYRPDFYHSETDAWIIFPWDKAET
VVELVAKRGLSIEEVSKITGESIDFIRRIFETRNKASTTSSRAGQD
>Mature_205_residues
TGIPHPQPTRFKPVSWREVEEGCAHIAEKILATNLNVDVIVGILRGGWIPARLLSDYLGVDTMGALEVKFYRGVGETAEK
PVITQPLIVNVRDKVVLVVDDVSDTGKTLTVAVNFLMHYGPRKIVTATLYVKPWSMYRPDFYHSETDAWIIFPWDKAETV
VELVAKRGLSIEEVSKITGESIDFIRRIFETRNKASTTSSRAGQD

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 23089; Mature: 22958

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGIPHPQPTRFKPVSWREVEEGCAHIAEKILATNLNVDVIVGILRGGWIPARLLSDYLG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHC
VDTMGALEVKFYRGVGETAEKPVITQPLIVNVRDKVVLVVDDVSDTGKTLTVAVNFLMHY
CCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHC
GPRKIVTATLYVKPWSMYRPDFYHSETDAWIIFPWDKAETVVELVAKRGLSIEEVSKITG
CCHHEEEEEEEEECCHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHCC
ESIDFIRRIFETRNKASTTSSRAGQD
CHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGIPHPQPTRFKPVSWREVEEGCAHIAEKILATNLNVDVIVGILRGGWIPARLLSDYLG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHC
VDTMGALEVKFYRGVGETAEKPVITQPLIVNVRDKVVLVVDDVSDTGKTLTVAVNFLMHY
CCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHC
GPRKIVTATLYVKPWSMYRPDFYHSETDAWIIFPWDKAETVVELVAKRGLSIEEVSKITG
CCHHEEEEEEEEECCHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHCC
ESIDFIRRIFETRNKASTTSSRAGQD
CHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA