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The map label for this gene is eriC [C]

Identifier: 124027316

GI number: 124027316

Start: 413751

End: 415442

Strand: Reverse

Name: eriC [C]

Synonym: Hbut_0425

Alternate gene names: 124027316

Gene position: 415442-413751 (Counterclockwise)

Preceding gene: 124027318

Following gene: 124027315

Centisome position: 24.92

GC content: 51.95

Gene sequence:

>1692_bases
ATGAGGAGGCTTCGTATACCCTCACTCGAAAAGTGGGTTATGCTAGGTACACTTGTCGGCGTAGTCTCAGGGCTTGCGGG
TACACTCTTAACGGTTGGTATCGAGGTTATAGCAGAGCTATTCGCGGAATATAGTGGTATAGACCTCATAAAGGGTGAGG
TTTCGGAGCCATCACTGGTACTGCCGTTACTGGTGGCCCTTGGCGGGCTAGCCTCCGGCTTGCTGACATACATGTTTGCA
CCTGAAGCAGAGGGTCATGGCACGGACTCGGTGCTGGAGGCGTTCCATTGGCGTGGCGCGTTTATAAGGCCACGGGTGCC
ACTGGTTAAGCTTGCTGCATCCTCGGCCCTCATAGGCCTTGGTGGGAGTGCAGGGAAGGAGGGTCCAATAGCGCTCATAG
GGGCTGGATTCGGCAGTGTATTGGCAGACATACTCCATCTTACGAGGAATGAGCGTCGCCTATTAGTCCTTGCAGGTGTT
GCAGGTGGAATTAGTGCCGTTTTCCGGGCTCCACTAGGTGCAATGCTGTTCGCTCTAGAGGTACCCTATAAGCGTGACAT
GGAGGTAGAAGCTATTCTTCCCCTGGGAGTGGCATCCATAGTAGCCTACGTGGCCTCGGTTACAATTCTCGGGTCGGGGC
GGCTCCTATGGCTTCCCGAGGTCGGACTCCAAAGCTCTCTCGAACTAGTCCTCTATGCGGTTCTCGGTATAGTTGCAGGT
CTCGTTGCAAAAGTATACGTTAGGCTCTTCTACGAAATACGTGACGCCTTCAAGGTGCTGCCAATACCTGTCATGTTGAA
GCCGGCTCTTGGCGGGCTTGTAGCCGGGTTTATAGGGCTGCTATTGCCCCATACACTAGGCCAAGGCTATCCGTTTCTCG
AAAGAGCATTGCTAGGCAAGCTAGCTTTACCAGTTATTGTAGCTGCGATAATAGGCAAGATGCTCACCAATGCGTTTAGC
ATAGCTTCTGGTGGCTCTGGAGGAGTGTTTGCCCCCTCACTCTTCATAGGCGGTATGCTCGGAGCTGCATTCGCGCAACT
ATACACGGACAATCCAGCCACGATAGCATCGTTCTCCGTGGTCGGCATGGCTGCGTTCTTTGCTGCTGCTGGCAAGGTGC
CCTTTACATCGATCATAATAGTCTCCGAGATAACAAGAGGCTACGAGCTAATAGTGCCATCGGTCGTAGCTGTAACACTC
TCCTATGTCGTCTCTGGCCAGGACTCGATATACGAGAAGCAGGTTAACACGCGTGCCGACTCTCCCTACTTCCTACGAGA
GCTGGGTGAAAGGCTGCTAAGGCAGATCAAGGTCCGTGATATAATGACGAGAAGCGTTGTCGTGGTGAGGCCCGACGATC
CATTGAAGCGTGTAATAGAGCTAACAGCCGAGACACACCATACAGGATTCCCTGTAGTTGTTGACGGTAGAGTTGTTGGC
ATGATAACTCTGAGTGACGTCCTACGCTATCGGCATAGTGAACTCGGAAAAGTAAAGGTCAAAGAAGCTATGACTAGAAG
CGTCATCGCAGTTCTGCCCGACGACTCGCTAGCAGATGCGCTTAGGAAAATGCTACGCTACGGTATCGGCAGGCTACCTG
TTGTAGAGAACTACGAGTCCATGAAGCTTATCGGGATAATAACCAAGAAGGATATTGTCAGAGCATATGAGACTATAAGA
TCCATACCATAG

Upstream 100 bases:

>100_bases
GGGGCTACCCGCTAGACGAGTACATACACCTGGCTGGCCAGAGAGGGCGCGGCAAGGAGCTTTCAAACAAGCTGGCGGAG
GTGGAGGCTCGACTAGAGAC

Downstream 100 bases:

>100_bases
TCTCCGGGCTCGTGGCTAACCGCCAGAGGGGGTTGGGCTGCTATGCTGCGCCTACTCATAATATCCGATGTGCATGCGGC
CTTTAAGAAGCTGGAGAAGC

Product: voltage-gated chloride channel protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MRRLRIPSLEKWVMLGTLVGVVSGLAGTLLTVGIEVIAELFAEYSGIDLIKGEVSEPSLVLPLLVALGGLASGLLTYMFA
PEAEGHGTDSVLEAFHWRGAFIRPRVPLVKLAASSALIGLGGSAGKEGPIALIGAGFGSVLADILHLTRNERRLLVLAGV
AGGISAVFRAPLGAMLFALEVPYKRDMEVEAILPLGVASIVAYVASVTILGSGRLLWLPEVGLQSSLELVLYAVLGIVAG
LVAKVYVRLFYEIRDAFKVLPIPVMLKPALGGLVAGFIGLLLPHTLGQGYPFLERALLGKLALPVIVAAIIGKMLTNAFS
IASGGSGGVFAPSLFIGGMLGAAFAQLYTDNPATIASFSVVGMAAFFAAAGKVPFTSIIIVSEITRGYELIVPSVVAVTL
SYVVSGQDSIYEKQVNTRADSPYFLRELGERLLRQIKVRDIMTRSVVVVRPDDPLKRVIELTAETHHTGFPVVVDGRVVG
MITLSDVLRYRHSELGKVKVKEAMTRSVIAVLPDDSLADALRKMLRYGIGRLPVVENYESMKLIGIITKKDIVRAYETIR
SIP

Sequences:

>Translated_563_residues
MRRLRIPSLEKWVMLGTLVGVVSGLAGTLLTVGIEVIAELFAEYSGIDLIKGEVSEPSLVLPLLVALGGLASGLLTYMFA
PEAEGHGTDSVLEAFHWRGAFIRPRVPLVKLAASSALIGLGGSAGKEGPIALIGAGFGSVLADILHLTRNERRLLVLAGV
AGGISAVFRAPLGAMLFALEVPYKRDMEVEAILPLGVASIVAYVASVTILGSGRLLWLPEVGLQSSLELVLYAVLGIVAG
LVAKVYVRLFYEIRDAFKVLPIPVMLKPALGGLVAGFIGLLLPHTLGQGYPFLERALLGKLALPVIVAAIIGKMLTNAFS
IASGGSGGVFAPSLFIGGMLGAAFAQLYTDNPATIASFSVVGMAAFFAAAGKVPFTSIIIVSEITRGYELIVPSVVAVTL
SYVVSGQDSIYEKQVNTRADSPYFLRELGERLLRQIKVRDIMTRSVVVVRPDDPLKRVIELTAETHHTGFPVVVDGRVVG
MITLSDVLRYRHSELGKVKVKEAMTRSVIAVLPDDSLADALRKMLRYGIGRLPVVENYESMKLIGIITKKDIVRAYETIR
SIP
>Mature_563_residues
MRRLRIPSLEKWVMLGTLVGVVSGLAGTLLTVGIEVIAELFAEYSGIDLIKGEVSEPSLVLPLLVALGGLASGLLTYMFA
PEAEGHGTDSVLEAFHWRGAFIRPRVPLVKLAASSALIGLGGSAGKEGPIALIGAGFGSVLADILHLTRNERRLLVLAGV
AGGISAVFRAPLGAMLFALEVPYKRDMEVEAILPLGVASIVAYVASVTILGSGRLLWLPEVGLQSSLELVLYAVLGIVAG
LVAKVYVRLFYEIRDAFKVLPIPVMLKPALGGLVAGFIGLLLPHTLGQGYPFLERALLGKLALPVIVAAIIGKMLTNAFS
IASGGSGGVFAPSLFIGGMLGAAFAQLYTDNPATIASFSVVGMAAFFAAAGKVPFTSIIIVSEITRGYELIVPSVVAVTL
SYVVSGQDSIYEKQVNTRADSPYFLRELGERLLRQIKVRDIMTRSVVVVRPDDPLKRVIELTAETHHTGFPVVVDGRVVG
MITLSDVLRYRHSELGKVKVKEAMTRSVIAVLPDDSLADALRKMLRYGIGRLPVVENYESMKLIGIITKKDIVRAYETIR
SIP

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786350, Length=359, Percent_Identity=29.5264623955432, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87081943, Length=340, Percent_Identity=30.2941176470588, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 60017; Mature: 60017

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRLRIPSLEKWVMLGTLVGVVSGLAGTLLTVGIEVIAELFAEYSGIDLIKGEVSEPSLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHH
LPLLVALGGLASGLLTYMFAPEAEGHGTDSVLEAFHWRGAFIRPRVPLVKLAASSALIGL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEC
GGSAGKEGPIALIGAGFGSVLADILHLTRNERRLLVLAGVAGGISAVFRAPLGAMLFALE
CCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHCCHHHHHHHHC
VPYKRDMEVEAILPLGVASIVAYVASVTILGSGRLLWLPEVGLQSSLELVLYAVLGIVAG
CCCCCCCCEEEECHHHHHHHHHHHHHHHEEECCCEEEECCCCCHHHHHHHHHHHHHHHHH
LVAKVYVRLFYEIRDAFKVLPIPVMLKPALGGLVAGFIGLLLPHTLGQGYPFLERALLGK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LALPVIVAAIIGKMLTNAFSIASGGSGGVFAPSLFIGGMLGAAFAQLYTDNPATIASFSV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VGMAAFFAAAGKVPFTSIIIVSEITRGYELIVPSVVAVTLSYVVSGQDSIYEKQVNTRAD
HHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
SPYFLRELGERLLRQIKVRDIMTRSVVVVRPDDPLKRVIELTAETHHTGFPVVVDGRVVG
CCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCCEEECCEEEE
MITLSDVLRYRHSELGKVKVKEAMTRSVIAVLPDDSLADALRKMLRYGIGRLPVVENYES
HHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCEECCCCC
MKLIGIITKKDIVRAYETIRSIP
EEEEEEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRRLRIPSLEKWVMLGTLVGVVSGLAGTLLTVGIEVIAELFAEYSGIDLIKGEVSEPSLV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHH
LPLLVALGGLASGLLTYMFAPEAEGHGTDSVLEAFHWRGAFIRPRVPLVKLAASSALIGL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHCCCEEEC
GGSAGKEGPIALIGAGFGSVLADILHLTRNERRLLVLAGVAGGISAVFRAPLGAMLFALE
CCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHCCHHHHHHHHC
VPYKRDMEVEAILPLGVASIVAYVASVTILGSGRLLWLPEVGLQSSLELVLYAVLGIVAG
CCCCCCCCEEEECHHHHHHHHHHHHHHHEEECCCEEEECCCCCHHHHHHHHHHHHHHHHH
LVAKVYVRLFYEIRDAFKVLPIPVMLKPALGGLVAGFIGLLLPHTLGQGYPFLERALLGK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LALPVIVAAIIGKMLTNAFSIASGGSGGVFAPSLFIGGMLGAAFAQLYTDNPATIASFSV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
VGMAAFFAAAGKVPFTSIIIVSEITRGYELIVPSVVAVTLSYVVSGQDSIYEKQVNTRAD
HHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
SPYFLRELGERLLRQIKVRDIMTRSVVVVRPDDPLKRVIELTAETHHTGFPVVVDGRVVG
CCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCCCEEECCEEEE
MITLSDVLRYRHSELGKVKVKEAMTRSVIAVLPDDSLADALRKMLRYGIGRLPVVENYES
HHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCCCEECCCCC
MKLIGIITKKDIVRAYETIRSIP
EEEEEEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]