| Definition | Prochlorococcus marinus str. NATL1A, complete genome. |
|---|---|
| Accession | NC_008819 |
| Length | 1,864,731 |
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The map label for this gene is acnB [H]
Identifier: 124026886
GI number: 124026886
Start: 1839141
End: 1841741
Strand: Direct
Name: acnB [H]
Synonym: NATL1_21811
Alternate gene names: 124026886
Gene position: 1839141-1841741 (Clockwise)
Preceding gene: 124026884
Following gene: 124026887
Centisome position: 98.63
GC content: 37.83
Gene sequence:
>2601_bases ATGCTAAAAGATTATTTATCACATGTTGCAGAAAGAGAAGCTTTGGGGATTCCTCCACTTCCTTTAGATGCAAAACAGAC TCAAGTTTTAACAGAGTTATTAGAAAAACCAGATCAAGGTATCGATCAAAACTTCTTACTTGATCTTCTTGTTAATCGAA TTCCTCCCGGAGTTGATCAAGCCTCTTATGTCAAAGCGACTTGGCTTAGCTCAATTGCTCAAGAAGAATCAAAAAGTCCG TTAGTAAATCCTCTAAAAGCAACTGAGCTTTTAGGTACAATGATTGGCGGATATAATGTAGCAGCGTTAATTGAAATACT AAAATCTAATAATAAAGAATTAGCGACTTCAGCCTGTTGTGCATTAAGTAATACCCTTTTAGTTTATGACGCTTTAAACG ACATTTTAGAATTAGCAAAAACTAATATTTATGCAGAAAAAGTTATCAATAGCTGGTCCAATGGAGAATGGTTCACTAAT AAACAACCATTAGCTCAAGAAATAACAGTAACAGTATTTAAAGTTGAAGGAGAAACAAATACAGACGACCTCTCTCCAGC AACTCATGCCACAACAAGACCAGATATTCCTTTACATGCTCTAGCGATGCTAGAGACTCGAGATCCAAATGGTTTAAGCA CTATTGAAGAATTAAAAAAGAAAGGATATCCAATTGCATATGTTGGCGATGTCGTTGGAACAGGAAGCTCTAGAAAGTCA GCAATTAACTCAGTTCTTTGGCATACAGGACAAGACATACCTTACGTACCAAATAAAAGAGGGAGTGGGGTTGTAATAGG AGGCAAAATTGCTCCTATTTTCTTTAATACTGCTGAAGATTCAGGTGCGCTTCCAATTGAATGCGATGTAAGCAATCTCA AAACAGGTGATGTAATTACTATTTTCCCTTACAAAGGAGAAGTTAGAAGAAGTAAAAATAAGACAAACAGTGGAGAACTT CTATCAAAATTTGACTTAAAACCACAAACTATTACTGATGAAGTAAGAGCGGGTGGGCGAATTCCTTTAATGATTGGAAG AGCTTTGACAGACAAAGTTAGAACAAAATTAAAACTTCCACCCTCTACTCTTTTTATTCGTCCTGGTCAGCCACCTGCAT CAAAGTATGGGTTTACACAAGCTCAAAAAATGGTTGGAAAAGCTTGCGGTTTAGAAGGCGTTCTCCCTGGTGCAAGTTGT GAGCCAATAATGACAACAGTTGGTAGTCAAGACACTACTGGTCCGATGACTAGAGATGAAATGAAAGAATTAGCCTGTTT AGGATTTTCTGCTGATTTAGTTATGCAGAGTTTCTGTCATACCGCAGCATATCCTAAGCCTGTTGATATCAAAACTCAAA AAGAACTCCCTGATTTTTTTGCTGAAAGAGGAGGAATAGCATTAAAACCCGGTGATGGAATTATTCACAGTTGGCTAAAC AGGATGCTTTTGCCGGACACAGTCGGGACAGGTGGCGATAGTCATACACGATTCCCGTTGGGCATCTCATTTCCAGGAGG TTCGGGAGTGGTGGCATTTGCGGCAGCCATTGGTTCCATGCCTTTAGATATGCCAGAGTCAGTTCTTGTTCGTTTTAAAG GGTCTTTACAAACTGGTGTCACTTTAAGAGATGTAGTTAATGCCATTCCGTGGATGGCCATACAAAAAGGTCTTCTGACC GTCGCAAAAGCAAACAAAGTTAATGTGTTCAATGGAAAGATATTAGAAATTGAAGGTCTACCAAACCTAAAATTAGAGCA AGCCTTTGAGTTGACTGATGCAAGTGCAGAAAGATCTTGTGCTGGATGTACTATTCAACTGTCTGAATCAACAATCAGTG AATATTTAAAAAGCAATATTGTTTTACTTAAAAATATGATTGCTAGGGGATATAAAGATGCCCGAACAATAAGTAGAAGA ATTAAAGAAATGGAAGATTGGTTAAAAAAACCAAATTTACTATCAGCCGACTCAAATGCTCAATACTCAGAAACCATCGA AATAGACTTGAATAAACTGAAAGAACCTGTTTTAGCTTGCCCTAATGATCCTGATAACGTCAAACTTTTAAGCGAAGTCG CAGGCACTCCCATTCAAGAAGTTTTTATTGGTTCGTGTATGACTAATATTGGTCATTATCGAGCCGCTGCAAAAATTCTC GAAGGAGAGGGGAAGATATCAGCACGATTATGGGTATGTCCGCCAACACGAATGGACGAAGAAATTTTGAAAAAAGAAGG ATACTACGAGATTTTTGAAAAAGCTGGTAGCCGAATGGAAATGCCTGGTTGTTCTCTATGCATGGGCAATCAAGCTCGTG TAGAAGATAATTCAACTGTTTTCTCAACAAGTACAAGAAATTTCAACAACAGATTAGGAAAAGGAGCTCAAGTGTTCTTA GGAAGTGCAGAATTGGCTGCTGTTTGCGCTTTGATAGGTCATATCCCTACAACTGATGAATATCTTGCAATAGCTTCCAA AAAAGTTTCACCAATAACTGACGAAATCTACAGATACTTAAACTTTAATGAAATACCAAACTTTATCGAAGATGGTCGTG TAATAACAAAAGAAGAAGAGGCCTCTATTTTACAAACCTAA
Upstream 100 bases:
>100_bases ATAAATTGCATTATCTGAATGTTTGTTCAAGAATCATGCGGTTGTAAACAATGAAAACAAAAGGCTCACACTCAAATACA TTCTCTGTTGAGATTTAAAA
Downstream 100 bases:
>100_bases ATTGAATTAAATGATCAAAAGTAAAAGTAAAAATCCAATACAAAAAAAATCAACTCAAAGCATAAAAAAACTTCTACAGA GGAAATGGCTAAATGTAATT
Product: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
Products: NA
Alternate protein names: Aconitase 2; 2-methylisocitrate dehydratase; Citrate hydro-lyase 2 [H]
Number of amino acids: Translated: 866; Mature: 866
Protein sequence:
>866_residues MLKDYLSHVAEREALGIPPLPLDAKQTQVLTELLEKPDQGIDQNFLLDLLVNRIPPGVDQASYVKATWLSSIAQEESKSP LVNPLKATELLGTMIGGYNVAALIEILKSNNKELATSACCALSNTLLVYDALNDILELAKTNIYAEKVINSWSNGEWFTN KQPLAQEITVTVFKVEGETNTDDLSPATHATTRPDIPLHALAMLETRDPNGLSTIEELKKKGYPIAYVGDVVGTGSSRKS AINSVLWHTGQDIPYVPNKRGSGVVIGGKIAPIFFNTAEDSGALPIECDVSNLKTGDVITIFPYKGEVRRSKNKTNSGEL LSKFDLKPQTITDEVRAGGRIPLMIGRALTDKVRTKLKLPPSTLFIRPGQPPASKYGFTQAQKMVGKACGLEGVLPGASC EPIMTTVGSQDTTGPMTRDEMKELACLGFSADLVMQSFCHTAAYPKPVDIKTQKELPDFFAERGGIALKPGDGIIHSWLN RMLLPDTVGTGGDSHTRFPLGISFPGGSGVVAFAAAIGSMPLDMPESVLVRFKGSLQTGVTLRDVVNAIPWMAIQKGLLT VAKANKVNVFNGKILEIEGLPNLKLEQAFELTDASAERSCAGCTIQLSESTISEYLKSNIVLLKNMIARGYKDARTISRR IKEMEDWLKKPNLLSADSNAQYSETIEIDLNKLKEPVLACPNDPDNVKLLSEVAGTPIQEVFIGSCMTNIGHYRAAAKIL EGEGKISARLWVCPPTRMDEEILKKEGYYEIFEKAGSRMEMPGCSLCMGNQARVEDNSTVFSTSTRNFNNRLGKGAQVFL GSAELAAVCALIGHIPTTDEYLAIASKKVSPITDEIYRYLNFNEIPNFIEDGRVITKEEEASILQT
Sequences:
>Translated_866_residues MLKDYLSHVAEREALGIPPLPLDAKQTQVLTELLEKPDQGIDQNFLLDLLVNRIPPGVDQASYVKATWLSSIAQEESKSP LVNPLKATELLGTMIGGYNVAALIEILKSNNKELATSACCALSNTLLVYDALNDILELAKTNIYAEKVINSWSNGEWFTN KQPLAQEITVTVFKVEGETNTDDLSPATHATTRPDIPLHALAMLETRDPNGLSTIEELKKKGYPIAYVGDVVGTGSSRKS AINSVLWHTGQDIPYVPNKRGSGVVIGGKIAPIFFNTAEDSGALPIECDVSNLKTGDVITIFPYKGEVRRSKNKTNSGEL LSKFDLKPQTITDEVRAGGRIPLMIGRALTDKVRTKLKLPPSTLFIRPGQPPASKYGFTQAQKMVGKACGLEGVLPGASC EPIMTTVGSQDTTGPMTRDEMKELACLGFSADLVMQSFCHTAAYPKPVDIKTQKELPDFFAERGGIALKPGDGIIHSWLN RMLLPDTVGTGGDSHTRFPLGISFPGGSGVVAFAAAIGSMPLDMPESVLVRFKGSLQTGVTLRDVVNAIPWMAIQKGLLT VAKANKVNVFNGKILEIEGLPNLKLEQAFELTDASAERSCAGCTIQLSESTISEYLKSNIVLLKNMIARGYKDARTISRR IKEMEDWLKKPNLLSADSNAQYSETIEIDLNKLKEPVLACPNDPDNVKLLSEVAGTPIQEVFIGSCMTNIGHYRAAAKIL EGEGKISARLWVCPPTRMDEEILKKEGYYEIFEKAGSRMEMPGCSLCMGNQARVEDNSTVFSTSTRNFNNRLGKGAQVFL GSAELAAVCALIGHIPTTDEYLAIASKKVSPITDEIYRYLNFNEIPNFIEDGRVITKEEEASILQT >Mature_866_residues MLKDYLSHVAEREALGIPPLPLDAKQTQVLTELLEKPDQGIDQNFLLDLLVNRIPPGVDQASYVKATWLSSIAQEESKSP LVNPLKATELLGTMIGGYNVAALIEILKSNNKELATSACCALSNTLLVYDALNDILELAKTNIYAEKVINSWSNGEWFTN KQPLAQEITVTVFKVEGETNTDDLSPATHATTRPDIPLHALAMLETRDPNGLSTIEELKKKGYPIAYVGDVVGTGSSRKS AINSVLWHTGQDIPYVPNKRGSGVVIGGKIAPIFFNTAEDSGALPIECDVSNLKTGDVITIFPYKGEVRRSKNKTNSGEL LSKFDLKPQTITDEVRAGGRIPLMIGRALTDKVRTKLKLPPSTLFIRPGQPPASKYGFTQAQKMVGKACGLEGVLPGASC EPIMTTVGSQDTTGPMTRDEMKELACLGFSADLVMQSFCHTAAYPKPVDIKTQKELPDFFAERGGIALKPGDGIIHSWLN RMLLPDTVGTGGDSHTRFPLGISFPGGSGVVAFAAAIGSMPLDMPESVLVRFKGSLQTGVTLRDVVNAIPWMAIQKGLLT VAKANKVNVFNGKILEIEGLPNLKLEQAFELTDASAERSCAGCTIQLSESTISEYLKSNIVLLKNMIARGYKDARTISRR IKEMEDWLKKPNLLSADSNAQYSETIEIDLNKLKEPVLACPNDPDNVKLLSEVAGTPIQEVFIGSCMTNIGHYRAAAKIL EGEGKISARLWVCPPTRMDEEILKKEGYYEIFEKAGSRMEMPGCSLCMGNQARVEDNSTVFSTSTRNFNNRLGKGAQVFL GSAELAAVCALIGHIPTTDEYLAIASKKVSPITDEIYRYLNFNEIPNFIEDGRVITKEEEASILQT
Specific function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate as well as the dehydration of 2-methylisocitrate to cis-2-methylaconitate [H]
COG id: COG1049
COG function: function code C; Aconitase B
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aconitase/IPM isomerase family [H]
Homologues:
Organism=Escherichia coli, GI2367097, Length=862, Percent_Identity=64.385150812065, Blast_Score=1088, Evalue=0.0, Organism=Escherichia coli, GI1786259, Length=386, Percent_Identity=25.9067357512953, Blast_Score=68, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6322261, Length=431, Percent_Identity=24.8259860788863, Blast_Score=84, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6323335, Length=401, Percent_Identity=26.6832917705736, Blast_Score=81, Evalue=9e-16, Organism=Drosophila melanogaster, GI161076999, Length=421, Percent_Identity=26.1282660332542, Blast_Score=74, Evalue=3e-13, Organism=Drosophila melanogaster, GI281365315, Length=423, Percent_Identity=26.7139479905437, Blast_Score=74, Evalue=4e-13, Organism=Drosophila melanogaster, GI17864292, Length=423, Percent_Identity=26.7139479905437, Blast_Score=74, Evalue=4e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015931 - InterPro: IPR015937 - InterPro: IPR001030 - InterPro: IPR015928 - InterPro: IPR018136 - InterPro: IPR004406 - InterPro: IPR015930 - InterPro: IPR015933 - InterPro: IPR015929 [H]
Pfam domain/function: PF00330 Aconitase; PF06434 Aconitase_2_N; PF11791 Aconitase_B_N [H]
EC number: =4.2.1.3; =4.2.1.99 [H]
Molecular weight: Translated: 94250; Mature: 94250
Theoretical pI: Translated: 5.56; Mature: 5.56
Prosite motif: PS00450 ACONITASE_1
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 4.0 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLKDYLSHVAEREALGIPPLPLDAKQTQVLTELLEKPDQGIDQNFLLDLLVNRIPPGVDQ CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC ASYVKATWLSSIAQEESKSPLVNPLKATELLGTMIGGYNVAALIEILKSNNKELATSACC HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHH ALSNTLLVYDALNDILELAKTNIYAEKVINSWSNGEWFTNKQPLAQEITVTVFKVEGETN HHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCC TDDLSPATHATTRPDIPLHALAMLETRDPNGLSTIEELKKKGYPIAYVGDVVGTGSSRKS CCCCCCCCCCCCCCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCEEEECCHHCCCCHHHH AINSVLWHTGQDIPYVPNKRGSGVVIGGKIAPIFFNTAEDSGALPIECDVSNLKTGDVIT HHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEEEECCCCCCCCEEEECCCCCCCCCEEE IFPYKGEVRRSKNKTNSGELLSKFDLKPQTITDEVRAGGRIPLMIGRALTDKVRTKLKLP EECCCCHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHEECCC PSTLFIRPGQPPASKYGFTQAQKMVGKACGLEGVLPGASCEPIMTTVGSQDTTGPMTRDE CCEEEEECCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHH MKELACLGFSADLVMQSFCHTAAYPKPVDIKTQKELPDFFAERGGIALKPGDGIIHSWLN HHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHH RMLLPDTVGTGGDSHTRFPLGISFPGGSGVVAFAAAIGSMPLDMPESVLVRFKGSLQTGV HHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCC TLRDVVNAIPWMAIQKGLLTVAKANKVNVFNGKILEIEGLPNLKLEQAFELTDASAERSC CHHHHHHHHHHHHHHHHHHEEECCCEEEEECCEEEEECCCCCCCHHHHHHHCCCCCCCCC AGCTIQLSESTISEYLKSNIVLLKNMIARGYKDARTISRRIKEMEDWLKKPNLLSADSNA CCCEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC QYSETIEIDLNKLKEPVLACPNDPDNVKLLSEVAGTPIQEVFIGSCMTNIGHYRAAAKIL CCCEEEEEEHHHHCCCCEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH EGEGKISARLWVCPPTRMDEEILKKEGYYEIFEKAGSRMEMPGCSLCMGNQARVEDNSTV CCCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHCCCEECCCCCCEECCCCCEECCCCEE FSTSTRNFNNRLGKGAQVFLGSAELAAVCALIGHIPTTDEYLAIASKKVSPITDEIYRYL EEECCCCHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHH NFNEIPNFIEDGRVITKEEEASILQT CHHHCCCHHHCCEEEEEHHHHHHCCC >Mature Secondary Structure MLKDYLSHVAEREALGIPPLPLDAKQTQVLTELLEKPDQGIDQNFLLDLLVNRIPPGVDQ CCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC ASYVKATWLSSIAQEESKSPLVNPLKATELLGTMIGGYNVAALIEILKSNNKELATSACC HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHH ALSNTLLVYDALNDILELAKTNIYAEKVINSWSNGEWFTNKQPLAQEITVTVFKVEGETN HHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEEECCCC TDDLSPATHATTRPDIPLHALAMLETRDPNGLSTIEELKKKGYPIAYVGDVVGTGSSRKS CCCCCCCCCCCCCCCCCHHHHEEEECCCCCCHHHHHHHHHCCCCEEEECCHHCCCCHHHH AINSVLWHTGQDIPYVPNKRGSGVVIGGKIAPIFFNTAEDSGALPIECDVSNLKTGDVIT HHHHHHHHCCCCCCCCCCCCCCEEEECCEEEEEEEECCCCCCCCEEEECCCCCCCCCEEE IFPYKGEVRRSKNKTNSGELLSKFDLKPQTITDEVRAGGRIPLMIGRALTDKVRTKLKLP EECCCCHHHHCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCEEEHHHHHHHHHHHEECCC PSTLFIRPGQPPASKYGFTQAQKMVGKACGLEGVLPGASCEPIMTTVGSQDTTGPMTRDE CCEEEEECCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCHHH MKELACLGFSADLVMQSFCHTAAYPKPVDIKTQKELPDFFAERGGIALKPGDGIIHSWLN HHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHH RMLLPDTVGTGGDSHTRFPLGISFPGGSGVVAFAAAIGSMPLDMPESVLVRFKGSLQTGV HHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCC TLRDVVNAIPWMAIQKGLLTVAKANKVNVFNGKILEIEGLPNLKLEQAFELTDASAERSC CHHHHHHHHHHHHHHHHHHEEECCCEEEEECCEEEEECCCCCCCHHHHHHHCCCCCCCCC AGCTIQLSESTISEYLKSNIVLLKNMIARGYKDARTISRRIKEMEDWLKKPNLLSADSNA CCCEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC QYSETIEIDLNKLKEPVLACPNDPDNVKLLSEVAGTPIQEVFIGSCMTNIGHYRAAAKIL CCCEEEEEEHHHHCCCCEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH EGEGKISARLWVCPPTRMDEEILKKEGYYEIFEKAGSRMEMPGCSLCMGNQARVEDNSTV CCCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHCCCEECCCCCCEECCCCCEECCCCEE FSTSTRNFNNRLGKGAQVFLGSAELAAVCALIGHIPTTDEYLAIASKKVSPITDEIYRYL EEECCCCHHHHCCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHH NFNEIPNFIEDGRVITKEEEASILQT CHHHCCCHHHCCEEEEEHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8905231 [H]