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The map label for this gene is gidA

Identifier: 124026850

GI number: 124026850

Start: 1802745

End: 1804715

Strand: Direct

Name: gidA

Synonym: NATL1_21451

Alternate gene names: 124026850

Gene position: 1802745-1804715 (Clockwise)

Preceding gene: 124026849

Following gene: 124026851

Centisome position: 96.68

GC content: 35.41

Gene sequence:

>1971_bases
ATGATTACTAAACAATCTTCAAATGAAAGTTTTGACGTAATTGTTGTAGGAGGTGGTCATGCAGGCTGCGAAGCAGCTCT
GACTTCAGCAAGATTAGGATTGAATACAGCTTTATTTACGCTCAATTTAGATCGAATCGCATGGCAGCCATGTAATCCCG
CAGTAGGGGGACCAGCTAAAAGTCAATTAGTTCATGAAGTTGATGCTCTAGGAGGGATAATCGGAAAATTAGCCGATTTA
ACGGCTCTTCAAAAAAGAGTGCTTAACGCAAGCAGAGGACCTGCAGTTAGAGCATTGAGAGCTCAAACAGATAAGCGATC
ATATGCACATGAAATGCTTAAAATTCTGCAAAACACGCCAAATTTAAAGATTAGAGAGGCAATGGTTACTGGGCTAGAAA
TTGAACATTATCCCAATCAGATTGACCAAAAGACACCAGAAATTCAAGAGAGAATTGGATTTATCAAGGGAATTAAAACC
TATTTTGGAAGCGTTTTTCATGCAAAAGCAGTTGTACTTACAACAGGCACATTTTTAGGAGGCAGAATTTGGATTGGCAA
TCAATCTATGAGCGCCGGTCGAGCAGGAGAGCAAGCCTCTGAGGGGTTAACTGAAGAATTAAAAAAGTTAGGCTTTACTA
CTGATCGTTTAAAAACAGGCACACCTGCTCGCGTCGACAGACGAACTATTGATCTTGACTCCCTCGATGAGCAATTGAGC
GATGCTTCAGATAAATTCTTTTCTTTTGATCCTCTTTCATGGAAAAGTGGAGAACAAATGAGTTGTCATATCACTCGAAC
AACAAAAGAAACTCACCAACTTATTAAAAATAATCTTCATTTAACTCCTATTTATGGAGGATTTATTGATAGTAAAGGTC
CCAGATATTGTCCATCGATTGAAGATAAAATTGTACGTTTTGCTGATAAAGATTCACACCAGATTTTCTTAGAACCCGAA
GGTAGAGATACTCCAGAAATGTATGTGCAAGGTTTCTCAACTGGACTGCCCGAAAACTTACAATTAGAACTTTTAAGGAC
ACTTCCAGGCTTACAAAATTGCGTGATGCTTAGACCTGCTTATGCAGTTGAATATGACTACATACCCGCCACACAATTAG
AAGCAACTCTAGAAACAAAGAGAATAAGTGGCTTATATAGTGCAGGCCAATTAAATGGAACGACAGGGTATGAAGAAGCT
GCAGCTCAAGGTTTAGTAGCAGGATTAAATGCTGCAAGATTAGTAAACAATAAAGAAGGAATTATTTTTGAAAGAGAAAG
TAGTTATATAGGAACTATGATTGACGATTTAGTTACAAAAGATCTAAAAGAACCATATAGAGTGTTAACCAGTAGAAGTG
AGTATAGATTAATCCTAAGGGGTGATAATGCAGATAGAAGATTAACTCCTCTTGGCTATCAATTAGGGTTAATTGATGAA
AGAAGATGGAATATATTTAATGCTAAACAACAATTAATCAATCAAGAGAAAGAAAGACTAGATAAAGAGAGAATAAAAGA
AAGTGATAAGTGTGCAAAGGAAATATTTTCCTCAACTGGAACACCTATAAAAGGATCATTAACATTAGCAAATTTTCTCA
GAAGAACAAATATTCACTATAAAGATTTAATTACTTATAATTTAACAACTCAAAGTATTCCTTTAGATGTTGAAGAAGCA
GTTGAGATAGATATTAAATATAGTGGTTATTTAGAAAGACAGAAAGCTCAAATAAATCAATTAAAACAGCAAAGCAAAAA
GTTATTACCAAAGAATTTAAATTACAATAATATAGAAACACTATCTAAAGAAGCTAGGGAGAAATTAACAATTTCTCAGC
CAAAAAGCCTTGGGCATGCTGCACAAGTGCCAGGCGTTAGCAAAGCTGATCTAACTGCACTTCTCGTATGGTTAAAAATC
GAGAAAATGAAAAAAGTTAAAAGAAAAGATTCACTTCAAATAACAAATTAA

Upstream 100 bases:

>100_bases
CCCGTTGGAACAGTTAAATTACTTTTTGAACCCCAATTCACTAGATTTAGAAATCTTGCTGCTTAATTGTTTGAAAATTT
ATTTCCTAAATGCTTAATTG

Downstream 100 bases:

>100_bases
TAACAGTGAATTCACGTCAATCTCCATTACCTTCTCCTGAAGTGATTTGGAAAGCATCGAAAGAAAATGTTCTTTCAGGG
AGAGGGAATCATAAGCTGTC

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 656; Mature: 656

Protein sequence:

>656_residues
MITKQSSNESFDVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADL
TALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTPNLKIREAMVTGLEIEHYPNQIDQKTPEIQERIGFIKGIKT
YFGSVFHAKAVVLTTGTFLGGRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLS
DASDKFFSFDPLSWKSGEQMSCHITRTTKETHQLIKNNLHLTPIYGGFIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPE
GRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPAYAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEA
AAQGLVAGLNAARLVNNKEGIIFERESSYIGTMIDDLVTKDLKEPYRVLTSRSEYRLILRGDNADRRLTPLGYQLGLIDE
RRWNIFNAKQQLINQEKERLDKERIKESDKCAKEIFSSTGTPIKGSLTLANFLRRTNIHYKDLITYNLTTQSIPLDVEEA
VEIDIKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIETLSKEAREKLTISQPKSLGHAAQVPGVSKADLTALLVWLKI
EKMKKVKRKDSLQITN

Sequences:

>Translated_656_residues
MITKQSSNESFDVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADL
TALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTPNLKIREAMVTGLEIEHYPNQIDQKTPEIQERIGFIKGIKT
YFGSVFHAKAVVLTTGTFLGGRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLS
DASDKFFSFDPLSWKSGEQMSCHITRTTKETHQLIKNNLHLTPIYGGFIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPE
GRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPAYAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEA
AAQGLVAGLNAARLVNNKEGIIFERESSYIGTMIDDLVTKDLKEPYRVLTSRSEYRLILRGDNADRRLTPLGYQLGLIDE
RRWNIFNAKQQLINQEKERLDKERIKESDKCAKEIFSSTGTPIKGSLTLANFLRRTNIHYKDLITYNLTTQSIPLDVEEA
VEIDIKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIETLSKEAREKLTISQPKSLGHAAQVPGVSKADLTALLVWLKI
EKMKKVKRKDSLQITN
>Mature_656_residues
MITKQSSNESFDVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGIIGKLADL
TALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTPNLKIREAMVTGLEIEHYPNQIDQKTPEIQERIGFIKGIKT
YFGSVFHAKAVVLTTGTFLGGRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLS
DASDKFFSFDPLSWKSGEQMSCHITRTTKETHQLIKNNLHLTPIYGGFIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPE
GRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPAYAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEA
AAQGLVAGLNAARLVNNKEGIIFERESSYIGTMIDDLVTKDLKEPYRVLTSRSEYRLILRGDNADRRLTPLGYQLGLIDE
RRWNIFNAKQQLINQEKERLDKERIKESDKCAKEIFSSTGTPIKGSLTLANFLRRTNIHYKDLITYNLTTQSIPLDVEEA
VEIDIKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIETLSKEAREKLTISQPKSLGHAAQVPGVSKADLTALLVWLKI
EKMKKVKRKDSLQITN

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=662, Percent_Identity=37.9154078549849, Blast_Score=409, Evalue=1e-114,
Organism=Homo sapiens, GI19882217, Length=687, Percent_Identity=36.5356622998544, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI183227703, Length=702, Percent_Identity=35.7549857549858, Blast_Score=390, Evalue=1e-108,
Organism=Escherichia coli, GI2367273, Length=638, Percent_Identity=46.3949843260188, Blast_Score=560, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17534255, Length=633, Percent_Identity=38.3886255924171, Blast_Score=416, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6321202, Length=633, Percent_Identity=39.4944707740916, Blast_Score=446, Evalue=1e-126,
Organism=Drosophila melanogaster, GI24658174, Length=652, Percent_Identity=37.5766871165644, Blast_Score=402, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_PROM1 (A2C5E1)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015965.1
- ProteinModelPortal:   A2C5E1
- SMR:   A2C5E1
- STRING:   A2C5E1
- GeneID:   4780742
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_21451
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- ProtClustDB:   PRK05192
- BioCyc:   PMAR167555:NATL1_21451-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 73284; Mature: 73284

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: BINDING 129-129 BINDING 200-200 BINDING 390-390

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITKQSSNESFDVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAK
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCCCCCCCHH
SQLVHEVDALGGIIGKLADLTALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
NLKIREAMVTGLEIEHYPNQIDQKTPEIQERIGFIKGIKTYFGSVFHAKAVVLTTGTFLG
CCEEHHHHHHCCEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEC
GRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLS
CEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEECHHHHHHHHH
DASDKFFSFDPLSWKSGEQMSCHITRTTKETHQLIKNNLHLTPIYGGFIDSKGPRYCPSI
HHHCCCEECCCCCCCCCCCEEEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCH
EDKIVRFADKDSHQIFLEPEGRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPA
HHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCC
YAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEAAAQGLVAGLNAARLVNNKEG
CEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCC
IIFERESSYIGTMIDDLVTKDLKEPYRVLTSRSEYRLILRGDNADRRLTPLGYQLGLIDE
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCEEECCCCC
RRWNIFNAKQQLINQEKERLDKERIKESDKCAKEIFSSTGTPIKGSLTLANFLRRTNIHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
KDLITYNLTTQSIPLDVEEAVEIDIKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIET
HHEEEEEEECCCCCCCHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
LSKEAREKLTISQPKSLGHAAQVPGVSKADLTALLVWLKIEKMKKVKRKDSLQITN
HHHHHHHCCCCCCCHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MITKQSSNESFDVIVVGGGHAGCEAALTSARLGLNTALFTLNLDRIAWQPCNPAVGGPAK
CCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCCCCCCCHH
SQLVHEVDALGGIIGKLADLTALQKRVLNASRGPAVRALRAQTDKRSYAHEMLKILQNTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
NLKIREAMVTGLEIEHYPNQIDQKTPEIQERIGFIKGIKTYFGSVFHAKAVVLTTGTFLG
CCEEHHHHHHCCEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEC
GRIWIGNQSMSAGRAGEQASEGLTEELKKLGFTTDRLKTGTPARVDRRTIDLDSLDEQLS
CEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEECHHHHHHHHH
DASDKFFSFDPLSWKSGEQMSCHITRTTKETHQLIKNNLHLTPIYGGFIDSKGPRYCPSI
HHHCCCEECCCCCCCCCCCEEEEEEECCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCH
EDKIVRFADKDSHQIFLEPEGRDTPEMYVQGFSTGLPENLQLELLRTLPGLQNCVMLRPA
HHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCC
YAVEYDYIPATQLEATLETKRISGLYSAGQLNGTTGYEEAAAQGLVAGLNAARLVNNKEG
CEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCC
IIFERESSYIGTMIDDLVTKDLKEPYRVLTSRSEYRLILRGDNADRRLTPLGYQLGLIDE
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCEEECCCCC
RRWNIFNAKQQLINQEKERLDKERIKESDKCAKEIFSSTGTPIKGSLTLANFLRRTNIHY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCC
KDLITYNLTTQSIPLDVEEAVEIDIKYSGYLERQKAQINQLKQQSKKLLPKNLNYNNIET
HHEEEEEEECCCCCCCHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
LSKEAREKLTISQPKSLGHAAQVPGVSKADLTALLVWLKIEKMKKVKRKDSLQITN
HHHHHHHCCCCCCCHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA