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The map label for this gene is asd [H]

Identifier: 124026827

GI number: 124026827

Start: 1779439

End: 1780476

Strand: Reverse

Name: asd [H]

Synonym: NATL1_21221

Alternate gene names: 124026827

Gene position: 1780476-1779439 (Counterclockwise)

Preceding gene: 124026833

Following gene: 124026826

Centisome position: 95.48

GC content: 38.15

Gene sequence:

>1038_bases
TTGAAACCAAAATCTCTTCTTCCAAATAGACCACTTACAGTTGCGATTCTTGGATCGAGTGGAGCTGTAGGAAAGGAATT
ATTGGCTTTGCTTGAAGAGAGATCATTCCCTGTTGGAAAATTAATTTTACTAGCCTCCCATCGCTCAGCAGGGGACATTC
AGAGTTTTTGTGGAACTGAGGTGAAAGTCGAAGAGACAACTAAAGATAGTTTTAAAAATGTAGATTTAATTTTGGCTTCA
GCTGGTAGTTCAATATCTCGTAAATGGAAAGATATAATTCAAAGTTCTGGAGCTTTGATGATTGATAACTCTAGTGCATT
TCGAATGGACGAGAATGTTCCTTTGATCGTTCCAGAAGTTAATCCTTCTGATGCTATTAAGCACAAAGGTGTAATTTCTA
ATCCGAATTGCACGACTATTTTATTAGCTTTGGTTCTATCTCCATTGACTAGGCATATCCCCATTAAGAGGATCGTTGTA
TCAACCTATCAATCCGCTAGTGGTGCAGGTGCAATGGCAATGGAAGAATTAGAAAAATTAAGCCAACAAGTTTTAGATGG
AATAACTCCAAAAAGTAAAGTTCTTCCGTATTCTTTGGCGTTTAATCTTTTTTTGCATAATTCCCCTTTGCAATCGAATA
ATTATTGCGAGGAAGAGATGAAAATGGTTAATGAAACCCGAAAGATTCTTGGAGATCCCGAACTTTCATTGACCGCAACA
TGTGTAAGAGTCCCAGTCTTAAGAGCCCATTCTGAATCGGTCAATATTGAATTTACAAAGCCTTTTCCAGTAAAAGAAGC
TTATAAGATTTTGGAGGCTTCACCGGGAGTTGAAATACTTGAGGACTTGGAAAATAATCGTTTTCCGATGCCTCAAGATG
TAACTGGCAGAGATCCAATATCAGTTGGTCGAATAAGGCAAGATATAAGTAACCCGAATGCTTTGGAACTATGGTTATGT
GGAGATCAAATCCGCAAGGGTGCAGCACTTAATGCAGTGCAGATTGCTGAACTTCTACTGCCAAAGAATTATGAATAA

Upstream 100 bases:

>100_bases
AAGCTATTGTGGCCTAAAAAGCATCGAAAAATTTGTTATTTGTTGATTTTTCCAATAAGAAAAACTTTTTTATTCAACCT
TTTAATTTTCTTCATCAAGT

Downstream 100 bases:

>100_bases
GTCAGCTTTATTATCACCAGCTCCTTTTGGAAGGCTCCTAACCGCAATGGTGACCCCATTTGATGATGAAGGGAAAGTTG
ATTATGGTCTTGCTGCCGAT

Product: aspartate semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKPKSLLPNRPLTVAILGSSGAVGKELLALLEERSFPVGKLILLASHRSAGDIQSFCGTEVKVEETTKDSFKNVDLILAS
AGSSISRKWKDIIQSSGALMIDNSSAFRMDENVPLIVPEVNPSDAIKHKGVISNPNCTTILLALVLSPLTRHIPIKRIVV
STYQSASGAGAMAMEELEKLSQQVLDGITPKSKVLPYSLAFNLFLHNSPLQSNNYCEEEMKMVNETRKILGDPELSLTAT
CVRVPVLRAHSESVNIEFTKPFPVKEAYKILEASPGVEILEDLENNRFPMPQDVTGRDPISVGRIRQDISNPNALELWLC
GDQIRKGAALNAVQIAELLLPKNYE

Sequences:

>Translated_345_residues
MKPKSLLPNRPLTVAILGSSGAVGKELLALLEERSFPVGKLILLASHRSAGDIQSFCGTEVKVEETTKDSFKNVDLILAS
AGSSISRKWKDIIQSSGALMIDNSSAFRMDENVPLIVPEVNPSDAIKHKGVISNPNCTTILLALVLSPLTRHIPIKRIVV
STYQSASGAGAMAMEELEKLSQQVLDGITPKSKVLPYSLAFNLFLHNSPLQSNNYCEEEMKMVNETRKILGDPELSLTAT
CVRVPVLRAHSESVNIEFTKPFPVKEAYKILEASPGVEILEDLENNRFPMPQDVTGRDPISVGRIRQDISNPNALELWLC
GDQIRKGAALNAVQIAELLLPKNYE
>Mature_345_residues
MKPKSLLPNRPLTVAILGSSGAVGKELLALLEERSFPVGKLILLASHRSAGDIQSFCGTEVKVEETTKDSFKNVDLILAS
AGSSISRKWKDIIQSSGALMIDNSSAFRMDENVPLIVPEVNPSDAIKHKGVISNPNCTTILLALVLSPLTRHIPIKRIVV
STYQSASGAGAMAMEELEKLSQQVLDGITPKSKVLPYSLAFNLFLHNSPLQSNNYCEEEMKMVNETRKILGDPELSLTAT
CVRVPVLRAHSESVNIEFTKPFPVKEAYKILEASPGVEILEDLENNRFPMPQDVTGRDPISVGRIRQDISNPNALELWLC
GDQIRKGAALNAVQIAELLLPKNYE

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=334, Percent_Identity=35.3293413173653, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1789841, Length=354, Percent_Identity=27.683615819209, Blast_Score=96, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=388, Percent_Identity=28.0927835051546, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37749; Mature: 37749

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKSLLPNRPLTVAILGSSGAVGKELLALLEERSFPVGKLILLASHRSAGDIQSFCGTE
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCC
VKVEETTKDSFKNVDLILASAGSSISRKWKDIIQSSGALMIDNSSAFRMDENVPLIVPEV
EEEECCCHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEEECC
NPSDAIKHKGVISNPNCTTILLALVLSPLTRHIPIKRIVVSTYQSASGAGAMAMEELEKL
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
SQQVLDGITPKSKVLPYSLAFNLFLHNSPLQSNNYCEEEMKMVNETRKILGDPELSLTAT
HHHHHHCCCCCHHCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHH
CVRVPVLRAHSESVNIEFTKPFPVKEAYKILEASPGVEILEDLENNRFPMPQDVTGRDPI
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCC
SVGRIRQDISNPNALELWLCGDQIRKGAALNAVQIAELLLPKNYE
HHHHHHHHHCCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKPKSLLPNRPLTVAILGSSGAVGKELLALLEERSFPVGKLILLASHRSAGDIQSFCGTE
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHCCCC
VKVEETTKDSFKNVDLILASAGSSISRKWKDIIQSSGALMIDNSSAFRMDENVPLIVPEV
EEEECCCHHHHCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCEEECCCCCEEEECC
NPSDAIKHKGVISNPNCTTILLALVLSPLTRHIPIKRIVVSTYQSASGAGAMAMEELEKL
CCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHH
SQQVLDGITPKSKVLPYSLAFNLFLHNSPLQSNNYCEEEMKMVNETRKILGDPELSLTAT
HHHHHHCCCCCHHCCCHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHH
CVRVPVLRAHSESVNIEFTKPFPVKEAYKILEASPGVEILEDLENNRFPMPQDVTGRDPI
HHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCC
SVGRIRQDISNPNALELWLCGDQIRKGAALNAVQIAELLLPKNYE
HHHHHHHHHCCCCEEEEEEECHHHHCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]