Click here to switch to the map view.

The map label for this gene is 124026825

Identifier: 124026825

GI number: 124026825

Start: 1776515

End: 1778464

Strand: Reverse

Name: 124026825

Synonym: NATL1_21201

Alternate gene names: NA

Gene position: 1778464-1776515 (Counterclockwise)

Preceding gene: 124026826

Following gene: 124026823

Centisome position: 95.37

GC content: 40.87

Gene sequence:

>1950_bases
ATGACATCAAGTTCAATGAATTCTCAAGGTTCAAAAAATAATCAAACCAAATCTCCTTGTTTGAGGATTATTCCCTTAGG
CGGCCTCGGAGAAATCGGTAAAAATACTTGCGTCTTTGAATACGGAAACGACATCATGATTCTTGATGCTGGTCTTGCTT
TCCCAACTGATGGGATGCATGGAGTAAATGTTGTCATGCCAGACACTACTTATCTACGAGAAAATCAAAATCGAATAAGA
GGTTTGGTGGTTACTCATGGGCATGAGGATCATATTGGTGGAATTTCTCATCATTTAAAGAACTTTAATATTCCAATTGT
TTACGGCCCTCCCCTAGCTATGTCTATGCTGAGGGGGAAAATGGAGGAAGCTGGAGTTGCTGATCGGACAACAATACAAG
TATGTGGACCAAGAGAGGTTATTAAAGTTGGGCAACATTTTTCAGTTGAATTTGTAAGAAATACGCATTCAATTTCTGAT
AGTTATTCCTTTGCAGTTACGACTCCAGTGGGAGTAGTATTTTTCACTGGAGATTTTAAGTTCGACCATACCCCACCTGA
CGGACAGCCTGCAGATTTAGCCAGGATGGCTCACTATGGAGACAAAGGTGTTCTTTGCCTTCTATCTGATTCAACCAACT
CTGAAGTTACAGGATTCACGCCCTCTGAATATTCTGTTTTTCCAAATTTAGATAGATACATTGCTACTGCTGAAGGCAGA
GTTATGGTTACTACTTTTGCTAGTTCAACTCATCGTGTGGCGATGCTTTTGGAGCTAGCAATGAAAAACGGTAGAAAGGT
TGGCTTGCTAGGTCGTTCAATGCTGAATGTGGTTGGTAAGGCAAGGGAACTTGGTTATATGCGTTTTCCTGATGATTTAT
TTTTTCCAATTAAACAGATCAGAGATTTGCCTGATAGAGAGACTTTTTTATTGATGACAGGTAGTCAAGGAGAATCAATG
GCTGCTTTAAGCCGTATTGCTAGAGGCGAGCATCAACATGTTCAATTGAAAACTAGTGATACTGTTATTTTTTCTGCTAG
CCCTATTCCTGGGAACACTATTTCTGTGATGCATACGATTGATAAATTAATCAAACTGGGTGCAAAAGTAATTTATGGCA
AAGATAAGGGGATTCATGTTTCAGGCCATGGATGCCAAGAAGATCAAAAATGGATGCTTGGATTAACAAGACCTAAATAC
TTCATTCCTGTTCATGGTGAGTACAGAATGCAAGTTTTACATGGGAAAACTGCTGTCTCAATGGGGGTGCATCCAGAGAA
TGTATTGGTGATGGAAAATGGGGACGTTGCTGAATTAAGACCAGATTCTCTATTGCAAGGCTCACCAGTTAAATCTGGAG
TGGAATTACTCGATTCTTCTAGAACGGGGATTGTGGATACTCGAGTATTAAAAGAACGTCAGCAACTTGCTGATGATGGA
GTTATCACCGTTCTTACTCCAATTAGTACTGATGGGGTGATGGTTGCACCACCTAGGGTAAATCTTCGTGGTGTTATCAC
TAATGTTGATGCCAAAACCATGGTTAATTGGACTGAAAGAGAGATTAATTGGGTCTTAGAAAATCGATGGAAACAGCTCG
TTCTTAAGACTGGGGGAAAATCAGTTGAGGTCGATTGGATAGGATTGCAAAGAGAGGTTGAATCAGGATTATCTCGTCGG
TTGAGAAGAGAGGTTCAAGCGGAGCCTTTAGTTCTTTGCCTTGTTCAACCTGCTCCAGGAGGAACTCGCGCATATAAACC
TCAACTTGATCAACAGCAAGATTCACGACAAGTAGTGAAGAAAACTACTGATAAAGCCCCTAAGACGACAAAGGCATCCG
TAGCAAATCAAGAGACAAGTTCACCAGCAGAACAAAAAACAAATAAGGAACCTAATGCTGAGGAAATGCCCACAGGAAGA
ACAAGACGTCGCAGATCAGCAATTAGCTGA

Upstream 100 bases:

>100_bases
ATACTCTCTTCTCTGAGATTGATTTGATCTACTCCCTCTATCCATAGTGGGTGTGGCTTTCATTTAGGTAACAATCAAGT
TTTTTCACATAAATTTTTCC

Downstream 100 bases:

>100_bases
TAACAAAAAAATTGTTTATTTTAATTAGTTTTATTTGAGATATAAATAGCTTCTTTGTTCCAACGTATTAGGAAGTCTCC
ATGAAGATGGATACTTCCAG

Product: metallo-beta-lactamase superfamily hydrolase

Products: NA

Alternate protein names: RNase J [H]

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MTSSSMNSQGSKNNQTKSPCLRIIPLGGLGEIGKNTCVFEYGNDIMILDAGLAFPTDGMHGVNVVMPDTTYLRENQNRIR
GLVVTHGHEDHIGGISHHLKNFNIPIVYGPPLAMSMLRGKMEEAGVADRTTIQVCGPREVIKVGQHFSVEFVRNTHSISD
SYSFAVTTPVGVVFFTGDFKFDHTPPDGQPADLARMAHYGDKGVLCLLSDSTNSEVTGFTPSEYSVFPNLDRYIATAEGR
VMVTTFASSTHRVAMLLELAMKNGRKVGLLGRSMLNVVGKARELGYMRFPDDLFFPIKQIRDLPDRETFLLMTGSQGESM
AALSRIARGEHQHVQLKTSDTVIFSASPIPGNTISVMHTIDKLIKLGAKVIYGKDKGIHVSGHGCQEDQKWMLGLTRPKY
FIPVHGEYRMQVLHGKTAVSMGVHPENVLVMENGDVAELRPDSLLQGSPVKSGVELLDSSRTGIVDTRVLKERQQLADDG
VITVLTPISTDGVMVAPPRVNLRGVITNVDAKTMVNWTEREINWVLENRWKQLVLKTGGKSVEVDWIGLQREVESGLSRR
LRREVQAEPLVLCLVQPAPGGTRAYKPQLDQQQDSRQVVKKTTDKAPKTTKASVANQETSSPAEQKTNKEPNAEEMPTGR
TRRRRSAIS

Sequences:

>Translated_649_residues
MTSSSMNSQGSKNNQTKSPCLRIIPLGGLGEIGKNTCVFEYGNDIMILDAGLAFPTDGMHGVNVVMPDTTYLRENQNRIR
GLVVTHGHEDHIGGISHHLKNFNIPIVYGPPLAMSMLRGKMEEAGVADRTTIQVCGPREVIKVGQHFSVEFVRNTHSISD
SYSFAVTTPVGVVFFTGDFKFDHTPPDGQPADLARMAHYGDKGVLCLLSDSTNSEVTGFTPSEYSVFPNLDRYIATAEGR
VMVTTFASSTHRVAMLLELAMKNGRKVGLLGRSMLNVVGKARELGYMRFPDDLFFPIKQIRDLPDRETFLLMTGSQGESM
AALSRIARGEHQHVQLKTSDTVIFSASPIPGNTISVMHTIDKLIKLGAKVIYGKDKGIHVSGHGCQEDQKWMLGLTRPKY
FIPVHGEYRMQVLHGKTAVSMGVHPENVLVMENGDVAELRPDSLLQGSPVKSGVELLDSSRTGIVDTRVLKERQQLADDG
VITVLTPISTDGVMVAPPRVNLRGVITNVDAKTMVNWTEREINWVLENRWKQLVLKTGGKSVEVDWIGLQREVESGLSRR
LRREVQAEPLVLCLVQPAPGGTRAYKPQLDQQQDSRQVVKKTTDKAPKTTKASVANQETSSPAEQKTNKEPNAEEMPTGR
TRRRRSAIS
>Mature_648_residues
TSSSMNSQGSKNNQTKSPCLRIIPLGGLGEIGKNTCVFEYGNDIMILDAGLAFPTDGMHGVNVVMPDTTYLRENQNRIRG
LVVTHGHEDHIGGISHHLKNFNIPIVYGPPLAMSMLRGKMEEAGVADRTTIQVCGPREVIKVGQHFSVEFVRNTHSISDS
YSFAVTTPVGVVFFTGDFKFDHTPPDGQPADLARMAHYGDKGVLCLLSDSTNSEVTGFTPSEYSVFPNLDRYIATAEGRV
MVTTFASSTHRVAMLLELAMKNGRKVGLLGRSMLNVVGKARELGYMRFPDDLFFPIKQIRDLPDRETFLLMTGSQGESMA
ALSRIARGEHQHVQLKTSDTVIFSASPIPGNTISVMHTIDKLIKLGAKVIYGKDKGIHVSGHGCQEDQKWMLGLTRPKYF
IPVHGEYRMQVLHGKTAVSMGVHPENVLVMENGDVAELRPDSLLQGSPVKSGVELLDSSRTGIVDTRVLKERQQLADDGV
ITVLTPISTDGVMVAPPRVNLRGVITNVDAKTMVNWTEREINWVLENRWKQLVLKTGGKSVEVDWIGLQREVESGLSRRL
RREVQAEPLVLCLVQPAPGGTRAYKPQLDQQQDSRQVVKKTTDKAPKTTKASVANQETSSPAEQKTNKEPNAEEMPTGRT
RRRRSAIS

Specific function: Unknown

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 71515; Mature: 71384

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSSMNSQGSKNNQTKSPCLRIIPLGGLGEIGKNTCVFEYGNDIMILDAGLAFPTDGMH
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCC
GVNVVMPDTTYLRENQNRIRGLVVTHGHEDHIGGISHHLKNFNIPIVYGPPLAMSMLRGK
CCEEEECCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHH
MEEAGVADRTTIQVCGPREVIKVGQHFSVEFVRNTHSISDSYSFAVTTPVGVVFFTGDFK
HHHCCCCCCCEEEEECCHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCEEEEEEECCEE
FDHTPPDGQPADLARMAHYGDKGVLCLLSDSTNSEVTGFTPSEYSVFPNLDRYIATAEGR
ECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCEECCCCHHEEEECCCE
VMVTTFASSTHRVAMLLELAMKNGRKVGLLGRSMLNVVGKARELGYMRFPDDLFFPIKQI
EEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCEECCHHHHHHHHHH
RDLPDRETFLLMTGSQGESMAALSRIARGEHQHVQLKTSDTVIFSASPIPGNTISVMHTI
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCHHHHHHHH
DKLIKLGAKVIYGKDKGIHVSGHGCQEDQKWMLGLTRPKYFIPVHGEYRMQVLHGKTAVS
HHHHHCCCEEEEECCCCEEEECCCCCCCCCEEEEECCCCEEEEECCCEEEEEEECCEEEE
MGVHPENVLVMENGDVAELRPDSLLQGSPVKSGVELLDSSRTGIVDTRVLKERQQLADDG
ECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VITVLTPISTDGVMVAPPRVNLRGVITNVDAKTMVNWTEREINWVLENRWKQLVLKTGGK
EEEEEEECCCCCEEECCCCCCEEEEEEECCHHHEECCHHHHHHHHHHHHHHHHHHHCCCC
SVEVDWIGLQREVESGLSRRLRREVQAEPLVLCLVQPAPGGTRAYKPQLDQQQDSRQVVK
EEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
KTTDKAPKTTKASVANQETSSPAEQKTNKEPNAEEMPTGRTRRRRSAIS
HHCCCCCCCCHHHHCCCCCCCCHHHHCCCCCCHHHCCCCHHHHHHHCCC
>Mature Secondary Structure 
TSSSMNSQGSKNNQTKSPCLRIIPLGGLGEIGKNTCVFEYGNDIMILDAGLAFPTDGMH
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCEEEEEECCCCCCCCCCC
GVNVVMPDTTYLRENQNRIRGLVVTHGHEDHIGGISHHLKNFNIPIVYGPPLAMSMLRGK
CCEEEECCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCCCEEEEECCHHHHHHHHHH
MEEAGVADRTTIQVCGPREVIKVGQHFSVEFVRNTHSISDSYSFAVTTPVGVVFFTGDFK
HHHCCCCCCCEEEEECCHHHHHCCCCEEEEEEECCCCCCCCCEEEEECCEEEEEEECCEE
FDHTPPDGQPADLARMAHYGDKGVLCLLSDSTNSEVTGFTPSEYSVFPNLDRYIATAEGR
ECCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCEECCCCHHEEEECCCE
VMVTTFASSTHRVAMLLELAMKNGRKVGLLGRSMLNVVGKARELGYMRFPDDLFFPIKQI
EEEEEECCCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCEECCHHHHHHHHHH
RDLPDRETFLLMTGSQGESMAALSRIARGEHQHVQLKTSDTVIFSASPIPGNTISVMHTI
CCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCCHHHHHHHH
DKLIKLGAKVIYGKDKGIHVSGHGCQEDQKWMLGLTRPKYFIPVHGEYRMQVLHGKTAVS
HHHHHCCCEEEEECCCCEEEECCCCCCCCCEEEEECCCCEEEEECCCEEEEEEECCEEEE
MGVHPENVLVMENGDVAELRPDSLLQGSPVKSGVELLDSSRTGIVDTRVLKERQQLADDG
ECCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
VITVLTPISTDGVMVAPPRVNLRGVITNVDAKTMVNWTEREINWVLENRWKQLVLKTGGK
EEEEEEECCCCCEEECCCCCCEEEEEEECCHHHEECCHHHHHHHHHHHHHHHHHHHCCCC
SVEVDWIGLQREVESGLSRRLRREVQAEPLVLCLVQPAPGGTRAYKPQLDQQQDSRQVVK
EEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHH
KTTDKAPKTTKASVANQETSSPAEQKTNKEPNAEEMPTGRTRRRRSAIS
HHCCCCCCCCHHHHCCCCCCCCHHHHCCCCCCHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]