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The map label for this gene is ftsW [H]

Identifier: 124026562

GI number: 124026562

Start: 1516476

End: 1517708

Strand: Direct

Name: ftsW [H]

Synonym: NATL1_18571

Alternate gene names: 124026562

Gene position: 1516476-1517708 (Clockwise)

Preceding gene: 124026550

Following gene: 124026563

Centisome position: 81.32

GC content: 33.9

Gene sequence:

>1233_bases
TTGAGTAATATTTCTAATAAAAAAATTCATTCAAAAACCAGAAGGAAAAATACTTTTGAATCAAAAGATTATCTGGGTAA
TTTATTAAGCAACAAAATACTTCCATTGCCTTGGTCTTTTTGGCCAAAGGAGGGGCGCTTGATCATGGGATTAATTGCCT
TTTGGAGCATATCAGGAATCTTTATCCTCGGATCAGCTAGTTGGTGGGTAGCAACTAGAGAAATGGGTGAAGGTGCTTAT
TACATAAAAAGACAACTAATTTGGCTGGTCGCAAGTTGGAGCATTTTCTACCTAGCTATAAATATCAATCTAAAAAATTG
GCTTAAACTATCAGGACCGTGCCTTTTTATAGGTATGGTTCTAATTGCATCAACAAGCTTTTTCGGTAGCACCGTTAATG
GGTCTACTCGATGGTTGATTATAGGCCCAGTACAAATTCAACCATCTGAATTAATCAAACCTTTTATCATTCTCCAAAGT
GCAAAGCTTTTTGGTCAATGGGAAAGAATAAATTCAGAAAAAAAAATTTTTTGGTTAACTATTTTTGCATCTATTGTTGT
ATTAATTATAAAGCAGCCAAATTTAAGCACAGCTGCATTAATAGGTATATTACTTTGGATGATTGCATTAGCATCCGGTA
TTAACTTCCGATATCTTTTCAACACCGCTATATCTGGTTTTTTCATTGGTGCAACAAGCATTTTTTTTAATGCCTATCAA
CAAAATCGCGTTATGTCATTTATAGACCCTTGGAAAGACCCACAAGGAAGTGGATATCAATTAATTCAGAGTCTTTATGC
TATTGGTTCAGGTGGTCTATTTGGAGAAGGTTATGGTCTTTCTATGCAAAAATTACAATACTTGCCCTACAGGAGTACTG
ATTTTATATTTGCTGTTTTTGCTGAAGAATTTGGATTCTTTGGATCAATTTTACTTTTATTATTTCTGCTTGTAGTTGCA
TACTTAACCCTGAAAATATCTCTTAATTGTAGAAATAATTATTCTAAACTAATCTCTATTGGATCAGGTACTATTCTTGT
TGGCCAATCAATTATGCATATAGCAGTTTCATCAGGAGCAATGCCTACAACTGGCCTTCCATTCCCTATGATTAGCTATG
GTGGAAACTCATTGATTTCAAGCTTACTAATAGCTGCCCTATTGGTCAGATCCTCTATTGAATCTTCAGAATTATTAATT
AAAAATCCCTCAAATAGACTTTTAGCTAGATAA

Upstream 100 bases:

>100_bases
TTGAATTTTCTGAAATTCGATAAAAAAGTACACTAACTACATTTAAAGACTTGGCAAGATGGCAATTAAGCGGCTCAATG
GTTTATAAGCAAAAGATCCT

Downstream 100 bases:

>100_bases
TCTGGAAGAAGAACTTAGAGTGGCAAATCTCTTTTTGAACATTTCTTCTATAAGTTTAATTTTCTCTGATTTGACTCGTC
ATGGCGAGCAGCTAATTAAT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSNISNKKIHSKTRRKNTFESKDYLGNLLSNKILPLPWSFWPKEGRLIMGLIAFWSISGIFILGSASWWVATREMGEGAY
YIKRQLIWLVASWSIFYLAININLKNWLKLSGPCLFIGMVLIASTSFFGSTVNGSTRWLIIGPVQIQPSELIKPFIILQS
AKLFGQWERINSEKKIFWLTIFASIVVLIIKQPNLSTAALIGILLWMIALASGINFRYLFNTAISGFFIGATSIFFNAYQ
QNRVMSFIDPWKDPQGSGYQLIQSLYAIGSGGLFGEGYGLSMQKLQYLPYRSTDFIFAVFAEEFGFFGSILLLLFLLVVA
YLTLKISLNCRNNYSKLISIGSGTILVGQSIMHIAVSSGAMPTTGLPFPMISYGGNSLISSLLIAALLVRSSIESSELLI
KNPSNRLLAR

Sequences:

>Translated_410_residues
MSNISNKKIHSKTRRKNTFESKDYLGNLLSNKILPLPWSFWPKEGRLIMGLIAFWSISGIFILGSASWWVATREMGEGAY
YIKRQLIWLVASWSIFYLAININLKNWLKLSGPCLFIGMVLIASTSFFGSTVNGSTRWLIIGPVQIQPSELIKPFIILQS
AKLFGQWERINSEKKIFWLTIFASIVVLIIKQPNLSTAALIGILLWMIALASGINFRYLFNTAISGFFIGATSIFFNAYQ
QNRVMSFIDPWKDPQGSGYQLIQSLYAIGSGGLFGEGYGLSMQKLQYLPYRSTDFIFAVFAEEFGFFGSILLLLFLLVVA
YLTLKISLNCRNNYSKLISIGSGTILVGQSIMHIAVSSGAMPTTGLPFPMISYGGNSLISSLLIAALLVRSSIESSELLI
KNPSNRLLAR
>Mature_409_residues
SNISNKKIHSKTRRKNTFESKDYLGNLLSNKILPLPWSFWPKEGRLIMGLIAFWSISGIFILGSASWWVATREMGEGAYY
IKRQLIWLVASWSIFYLAININLKNWLKLSGPCLFIGMVLIASTSFFGSTVNGSTRWLIIGPVQIQPSELIKPFIILQSA
KLFGQWERINSEKKIFWLTIFASIVVLIIKQPNLSTAALIGILLWMIALASGINFRYLFNTAISGFFIGATSIFFNAYQQ
NRVMSFIDPWKDPQGSGYQLIQSLYAIGSGGLFGEGYGLSMQKLQYLPYRSTDFIFAVFAEEFGFFGSILLLLFLLVVAY
LTLKISLNCRNNYSKLISIGSGTILVGQSIMHIAVSSGAMPTTGLPFPMISYGGNSLISSLLIAALLVRSSIESSELLIK
NPSNRLLAR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=346, Percent_Identity=32.3699421965318, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786853, Length=297, Percent_Identity=34.006734006734, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45727; Mature: 45595

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNISNKKIHSKTRRKNTFESKDYLGNLLSNKILPLPWSFWPKEGRLIMGLIAFWSISGI
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCE
FILGSASWWVATREMGEGAYYIKRQLIWLVASWSIFYLAININLKNWLKLSGPCLFIGMV
EEEECCCEEEEEHHHCCCHHHHHHHHHHHHEEEEEEEEEEEECHHHHHEECCCHHHHHHH
LIASTSFFGSTVNGSTRWLIIGPVQIQPSELIKPFIILQSAKLFGQWERINSEKKIFWLT
HHHHHHHCCCCCCCCEEEEEEEEEEECHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEHHH
IFASIVVLIIKQPNLSTAALIGILLWMIALASGINFRYLFNTAISGFFIGATSIFFNAYQ
HHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
QNRVMSFIDPWKDPQGSGYQLIQSLYAIGSGGLFGEGYGLSMQKLQYLPYRSTDFIFAVF
HCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEH
AEEFGFFGSILLLLFLLVVAYLTLKISLNCRNNYSKLISIGSGTILVGQSIMHIAVSSGA
HHHHCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCCEEEECCCEEEEEECCCC
MPTTGLPFPMISYGGNSLISSLLIAALLVRSSIESSELLIKNPSNRLLAR
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure 
SNISNKKIHSKTRRKNTFESKDYLGNLLSNKILPLPWSFWPKEGRLIMGLIAFWSISGI
CCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCE
FILGSASWWVATREMGEGAYYIKRQLIWLVASWSIFYLAININLKNWLKLSGPCLFIGMV
EEEECCCEEEEEHHHCCCHHHHHHHHHHHHEEEEEEEEEEEECHHHHHEECCCHHHHHHH
LIASTSFFGSTVNGSTRWLIIGPVQIQPSELIKPFIILQSAKLFGQWERINSEKKIFWLT
HHHHHHHCCCCCCCCEEEEEEEEEEECHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEHHH
IFASIVVLIIKQPNLSTAALIGILLWMIALASGINFRYLFNTAISGFFIGATSIFFNAYQ
HHHHHHEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
QNRVMSFIDPWKDPQGSGYQLIQSLYAIGSGGLFGEGYGLSMQKLQYLPYRSTDFIFAVF
HCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCCCCCCEEEEH
AEEFGFFGSILLLLFLLVVAYLTLKISLNCRNNYSKLISIGSGTILVGQSIMHIAVSSGA
HHHHCHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCCEEEECCCEEEEEECCCC
MPTTGLPFPMISYGGNSLISSLLIAALLVRSSIESSELLIKNPSNRLLAR
CCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]