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The map label for this gene is atpA [H]

Identifier: 124026554

GI number: 124026554

Start: 1511187

End: 1512701

Strand: Reverse

Name: atpA [H]

Synonym: NATL1_18491

Alternate gene names: 124026554

Gene position: 1512701-1511187 (Counterclockwise)

Preceding gene: 124026555

Following gene: 124026553

Centisome position: 81.12

GC content: 40.4

Gene sequence:

>1515_bases
ATGGTTTCTATACGTCCCGACGAGATCAGTTCAATCCTTAAACAGCAGATTGCTGATTACGATAAGTCAGTATCTGTAAG
CAATGTAGGTACCGTTTTACAAATCGGTGATGGTATCGCAAGAGTTTATGGCCTCGAAAAGGTTATGGCAGGTGAACTAG
TTGAATTCGAAGATGGAACAGAAGGGATTGCTTTAAACCTTGAAGATGACAATGTTGGTGTCGTTTTGATGGGTGAAGCT
TTAGGAGTACAAGAGGGAAGTACAGTTAAAGCAACTGGAAAGATTGCCTCAGTCCCAGTTGGTGAGGCAATGCTTGGAAG
AGTTGTTAATCCTCTTGGACAGCAAATCGATGGAAAAGGAGAGATTGCTACAACTGACACAAGATTAATTGAGTCAATAG
CACCTGGAATTATTAAGAGAAAGTCAGTACATGAGCCTATGCAAACTGGGATCACATCTATTGATGCGATGATCCCTATT
GGAAGAGGTCAGAGGGAGTTAATTATTGGAGATCGACAAACAGGGAAGACTGCAATAGCAATCGATACAATCATCAACCA
AAAAGGTCAAGATGTTGTTTGTGTTTATGTAGCTGTTGGTCAAAAACAAGCATCAGTGGCAAATGTGGTTGAAGTTCTTA
AAGAAAAAGGAGCTTTGGATTATACAATTATTGTTAATGCCGGAGCATCTGAAGCTGCAGCTTTGCAATATTTAGCTCCT
TATACAGGTGCTGCAATTGCTGAGCACTTTATGTATCAGGGCAAGGCGACACTAGTTATATACGATGATCTAACTAAGCA
AGCTCAGGCTTACAGGCAAATGTCATTACTCTTACGTCGTCCACTAGGCCGTGAAGCATATCCAGGAGATGTTTTCTATT
GTCATAGTCGTTTGCTTGAGAGGGCTGCAAAACTTTCTGATGCTATGGGTGCAGGATCAATGACATCCTTGCCTATTATT
GAAACGCAGGCTGGTGATGTTTCGGCTTATATCCCAACTAACGTCATATCAATTACTGATGGTCAGATTTTCTTGAGCTC
AGATTTATTCAACTCTGGATTAAGACCTGCAATTAACGTTGGTATATCGGTTAGTCGTGTAGGCGGAGCTGCGCAAACAA
AAGCTATTAAGAAAATTGCCGGTACGTTAAAACTTGAACTGGCTCAATTTGATGAACTTGCGGCATTCTCTCAATTTGCT
TCAGATCTTGATGAGGCTACTCAAAAGCAATTAGGTAGAGGTAAAAGGCTAAGAGAACTTCTCAAGCAGCCTCAATTTGA
TCCTCTAAATTTAGCTGAACAAGTAGCTATTGTTTATGCAGGAGTTAAAGGATTGATTGATGAGGTTCCCGAGGAGAAAG
TGGTTAACTTTGCTCGTGAATTGCGTGATTATTTAAAAACAAACAAGGCTGATTTCCTTAAAAATGTTCTTTCCGAAAAA
GTATTAAGTGAAGCATCTGAATCAATGCTTAAAGACGCTATTAGCGAGGTTAAGTCCTCCATGCTTGCGGCTTAA

Upstream 100 bases:

>100_bases
AGAAGACTTGGTCTTGCTTTGGCCAAAGTCAGCTAATTCTCTCCTGACTTTCTCCTCCCTTCTTCCTCTTTTTCTTCTTC
CCCAACTTTAAGTTAATCCC

Downstream 100 bases:

>100_bases
ACACAAAAGGCTATCTAAGAGAGACAATTACCTATGGCTAACCTAAAGGACATAAGAGACAGAATTGTCTCTGTCAAAAA
CACTAGGAAAATCACAGAAG

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MVSIRPDEISSILKQQIADYDKSVSVSNVGTVLQIGDGIARVYGLEKVMAGELVEFEDGTEGIALNLEDDNVGVVLMGEA
LGVQEGSTVKATGKIASVPVGEAMLGRVVNPLGQQIDGKGEIATTDTRLIESIAPGIIKRKSVHEPMQTGITSIDAMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGQDVVCVYVAVGQKQASVANVVEVLKEKGALDYTIIVNAGASEAAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPLGREAYPGDVFYCHSRLLERAAKLSDAMGAGSMTSLPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFDPLNLAEQVAIVYAGVKGLIDEVPEEKVVNFARELRDYLKTNKADFLKNVLSEK
VLSEASESMLKDAISEVKSSMLAA

Sequences:

>Translated_504_residues
MVSIRPDEISSILKQQIADYDKSVSVSNVGTVLQIGDGIARVYGLEKVMAGELVEFEDGTEGIALNLEDDNVGVVLMGEA
LGVQEGSTVKATGKIASVPVGEAMLGRVVNPLGQQIDGKGEIATTDTRLIESIAPGIIKRKSVHEPMQTGITSIDAMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGQDVVCVYVAVGQKQASVANVVEVLKEKGALDYTIIVNAGASEAAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPLGREAYPGDVFYCHSRLLERAAKLSDAMGAGSMTSLPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFDPLNLAEQVAIVYAGVKGLIDEVPEEKVVNFARELRDYLKTNKADFLKNVLSEK
VLSEASESMLKDAISEVKSSMLAA
>Mature_504_residues
MVSIRPDEISSILKQQIADYDKSVSVSNVGTVLQIGDGIARVYGLEKVMAGELVEFEDGTEGIALNLEDDNVGVVLMGEA
LGVQEGSTVKATGKIASVPVGEAMLGRVVNPLGQQIDGKGEIATTDTRLIESIAPGIIKRKSVHEPMQTGITSIDAMIPI
GRGQRELIIGDRQTGKTAIAIDTIINQKGQDVVCVYVAVGQKQASVANVVEVLKEKGALDYTIIVNAGASEAAALQYLAP
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPLGREAYPGDVFYCHSRLLERAAKLSDAMGAGSMTSLPII
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFA
SDLDEATQKQLGRGKRLRELLKQPQFDPLNLAEQVAIVYAGVKGLIDEVPEEKVVNFARELRDYLKTNKADFLKNVLSEK
VLSEASESMLKDAISEVKSSMLAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=496, Percent_Identity=59.8790322580645, Blast_Score=596, Evalue=1e-170,
Organism=Homo sapiens, GI4757810, Length=496, Percent_Identity=59.8790322580645, Blast_Score=596, Evalue=1e-170,
Organism=Homo sapiens, GI19913428, Length=302, Percent_Identity=29.1390728476821, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI19913426, Length=301, Percent_Identity=28.5714285714286, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI32189394, Length=395, Percent_Identity=24.3037974683544, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=53.7698412698413, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1790170, Length=424, Percent_Identity=25.4716981132075, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788251, Length=333, Percent_Identity=27.027027027027, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71988063, Length=495, Percent_Identity=59.3939393939394, Blast_Score=600, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI71988080, Length=495, Percent_Identity=59.3939393939394, Blast_Score=598, Evalue=1e-171,
Organism=Caenorhabditis elegans, GI71988074, Length=495, Percent_Identity=56.1616161616162, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI17510931, Length=296, Percent_Identity=27.7027027027027, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17570191, Length=299, Percent_Identity=28.0936454849498, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25144756, Length=416, Percent_Identity=24.7596153846154, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988068, Length=78, Percent_Identity=47.4358974358974, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=497, Percent_Identity=57.9476861167002, Blast_Score=572, Evalue=1e-164,
Organism=Saccharomyces cerevisiae, GI6319603, Length=351, Percent_Identity=28.4900284900285, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=413, Percent_Identity=25.4237288135593, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=59.6039603960396, Blast_Score=605, Evalue=1e-173,
Organism=Drosophila melanogaster, GI281361666, Length=349, Percent_Identity=27.7936962750716, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646341, Length=349, Percent_Identity=27.7936962750716, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136796, Length=349, Percent_Identity=27.7936962750716, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28574560, Length=446, Percent_Identity=26.2331838565022, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24638766, Length=406, Percent_Identity=25.3694581280788, Blast_Score=92, Evalue=6e-19,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 53977; Mature: 53977

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRPDEISSILKQQIADYDKSVSVSNVGTVLQIGDGIARVYGLEKVMAGELVEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHCCCEEECCCC
EGIALNLEDDNVGVVLMGEALGVQEGSTVKATGKIASVPVGEAMLGRVVNPLGQQIDGKG
CCEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEECCCCCHHHHHHHHHHHHHCCCCCC
EIATTDTRLIESIAPGIIKRKSVHEPMQTGITSIDAMIPIGRGQRELIIGDRQTGKTAIA
CEECHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHEEECCCCCCEEEEECCCCCCEEEE
IDTIINQKGQDVVCVYVAVGQKQASVANVVEVLKEKGALDYTIIVNAGASEAAALQYLAP
EEHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPLGREAYPGDVFYCHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RAAKLSDAMGAGSMTSLPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINV
HHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCEEEEECCCEEEECHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKQPQFDPLNLAEQVAIVYAGVKGLIDEVPEEKVVNFARELRDYLKTNKADFLKNVLSEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLSEASESMLKDAISEVKSSMLAA
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVSIRPDEISSILKQQIADYDKSVSVSNVGTVLQIGDGIARVYGLEKVMAGELVEFEDGT
CCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHCCHHHHHHHHHHHHHCCCEEECCCC
EGIALNLEDDNVGVVLMGEALGVQEGSTVKATGKIASVPVGEAMLGRVVNPLGQQIDGKG
CCEEEEECCCCCCEEEEECCCCCCCCCEEEECCCEECCCCCHHHHHHHHHHHHHCCCCCC
EIATTDTRLIESIAPGIIKRKSVHEPMQTGITSIDAMIPIGRGQRELIIGDRQTGKTAIA
CEECHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHEEECCCCCCEEEEECCCCCCEEEE
IDTIINQKGQDVVCVYVAVGQKQASVANVVEVLKEKGALDYTIIVNAGASEAAALQYLAP
EEHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHCC
YTGAAIAEHFMYQGKATLVIYDDLTKQAQAYRQMSLLLRRPLGREAYPGDVFYCHSRLLE
CHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
RAAKLSDAMGAGSMTSLPIIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINV
HHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCEEEEECCCEEEECHHHCCCCCCHHHC
GISVSRVGGAAQTKAIKKIAGTLKLELAQFDELAAFSQFASDLDEATQKQLGRGKRLREL
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKQPQFDPLNLAEQVAIVYAGVKGLIDEVPEEKVVNFARELRDYLKTNKADFLKNVLSEK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLSEASESMLKDAISEVKSSMLAA
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]