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The map label for this gene is melB [C]

Identifier: 124026455

GI number: 124026455

Start: 1432044

End: 1433447

Strand: Direct

Name: melB [C]

Synonym: NATL1_17501

Alternate gene names: 124026455

Gene position: 1432044-1433447 (Clockwise)

Preceding gene: 124026454

Following gene: 124026456

Centisome position: 76.8

GC content: 36.54

Gene sequence:

>1404_bases
GTGAATAATTCCACATCGATTTACGAAGGAAATAATCGCACAAGACTAATGATCTCTTATGCAATGGGAGATGCTGGAAC
GGGATTAGCCGCAATACAGCTAGGTACTTATCTATTTCTTTTTTTTACTTGTGCTGCAGGAATTCCTGCATTTATTGCAG
GCTCGCTTCTCATGGTTTCAAAACTTTGGGATGCGATAAATGATCCTCTAATTGGATGGATGAGTGATCGCACCAGATCA
AGATGGGGGCCAAGGCTTCCATGGATGATTGGAGGTGCTGTTCCACTTGGTTTATTCCTTGCCGCAATGTGGTGGGTCCC
TCCTGGAGATATAGATGCGAAAACAACTTATTACGTATTCGCAGCAATTTTTTTGATGACAGCTTATACAGCAGTAAATC
TACCTTTTGCAGCATTATCTACTGAGCTAACTGAAAATATAGCTATTAGAACAAGACTTAATGCTGCAAGATTTACTGGG
TCTATTATAGCTGGAACCACTGGATTAATAGTGGCTGCAGGCTTCTTATCTCAAGGAGTAGAAGGTTATACTTCAATGGG
AAGAGTAACAGGAGTTATTGCTACTTTTACCACATTAATTGCTTGCTGGGGACTAGCCCCATTTGCTAAAAAAGCCAGAA
AGCCCACTTCTCAATCAGAACCTTTTAATCAGCAGCTAAAAAGAGTTTTAAATAATAAACTTTTCACACGAATTATTGCT
CTTTACTTGCTGCTTTGGTGCGGACTGCAATTAATGCAAACCGTTTCATTAATCTATCTTGAGCAAGTAATGCTTGTTCC
AATAGAAATTTCAAAATGGATCCCTATACCATTTCAAATTAGTACTCTATTAGGTCTACAGTTTTGGAGCTTTTACTCCA
ATAAATATGGAAGAATATCAGCACTATTCAAAGGTGGGAAAATATGGATATTAGCCTGTTTTTTAGTTATATTTATGCCC
CCAATAACTAAAGGAGTCAGTATCAATTCTTTATTAGCCTTTGGTGATATTGAAGGTATAAAGCTGTTGATTCTTTTATT
AATAATTATTTTGGTAGGATTTGGAGCTTCAACAGCATATCTTATTCCTTGGTCCTTACTTCCTGATGCTATTGATCAAG
ATCCCGAAAAGCCTTCAGGAATATATACAGCATGGATGGTTTTTATTCAGAAAATAGGTATTGGTTTAAGCGTTCAATTT
CTAGGAGTTCTTTTATCTTTATCAGGATATAAATCATCCACTAATTGCTTATCAAGTCTTGAAGACCTAGATCAACCTCT
AACAGCAATTATTACTATTAGATTATGCATGGGATTAATACCTTCTTTGCTAGTAATTGCTGGATTAATAACTATGAAAC
CGTGGCGAAGTTTAGATTTCAAATCTAGAAGGTTAAGTCAATGA

Upstream 100 bases:

>100_bases
AACTACGCCCGCGCTAGAAATAAAAACTACTCACTGTTGGAGTAAAAGTTAATTTAGCTTTCTCCATTATTACCTTGCGA
GTCCCATTATCCAAAAAAGA

Downstream 100 bases:

>100_bases
ACTACTCACCTCGTTGGCTAAGAAGATTTTTTAGCAGTATTTTAATTGGAGGGCAAGCAATTGCATCAATAGCCAAAGGG
AATATAAATAAATCAGATTT

Product: GPH family sugar transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MNNSTSIYEGNNRTRLMISYAMGDAGTGLAAIQLGTYLFLFFTCAAGIPAFIAGSLLMVSKLWDAINDPLIGWMSDRTRS
RWGPRLPWMIGGAVPLGLFLAAMWWVPPGDIDAKTTYYVFAAIFLMTAYTAVNLPFAALSTELTENIAIRTRLNAARFTG
SIIAGTTGLIVAAGFLSQGVEGYTSMGRVTGVIATFTTLIACWGLAPFAKKARKPTSQSEPFNQQLKRVLNNKLFTRIIA
LYLLLWCGLQLMQTVSLIYLEQVMLVPIEISKWIPIPFQISTLLGLQFWSFYSNKYGRISALFKGGKIWILACFLVIFMP
PITKGVSINSLLAFGDIEGIKLLILLLIIILVGFGASTAYLIPWSLLPDAIDQDPEKPSGIYTAWMVFIQKIGIGLSVQF
LGVLLSLSGYKSSTNCLSSLEDLDQPLTAIITIRLCMGLIPSLLVIAGLITMKPWRSLDFKSRRLSQ

Sequences:

>Translated_467_residues
MNNSTSIYEGNNRTRLMISYAMGDAGTGLAAIQLGTYLFLFFTCAAGIPAFIAGSLLMVSKLWDAINDPLIGWMSDRTRS
RWGPRLPWMIGGAVPLGLFLAAMWWVPPGDIDAKTTYYVFAAIFLMTAYTAVNLPFAALSTELTENIAIRTRLNAARFTG
SIIAGTTGLIVAAGFLSQGVEGYTSMGRVTGVIATFTTLIACWGLAPFAKKARKPTSQSEPFNQQLKRVLNNKLFTRIIA
LYLLLWCGLQLMQTVSLIYLEQVMLVPIEISKWIPIPFQISTLLGLQFWSFYSNKYGRISALFKGGKIWILACFLVIFMP
PITKGVSINSLLAFGDIEGIKLLILLLIIILVGFGASTAYLIPWSLLPDAIDQDPEKPSGIYTAWMVFIQKIGIGLSVQF
LGVLLSLSGYKSSTNCLSSLEDLDQPLTAIITIRLCMGLIPSLLVIAGLITMKPWRSLDFKSRRLSQ
>Mature_467_residues
MNNSTSIYEGNNRTRLMISYAMGDAGTGLAAIQLGTYLFLFFTCAAGIPAFIAGSLLMVSKLWDAINDPLIGWMSDRTRS
RWGPRLPWMIGGAVPLGLFLAAMWWVPPGDIDAKTTYYVFAAIFLMTAYTAVNLPFAALSTELTENIAIRTRLNAARFTG
SIIAGTTGLIVAAGFLSQGVEGYTSMGRVTGVIATFTTLIACWGLAPFAKKARKPTSQSEPFNQQLKRVLNNKLFTRIIA
LYLLLWCGLQLMQTVSLIYLEQVMLVPIEISKWIPIPFQISTLLGLQFWSFYSNKYGRISALFKGGKIWILACFLVIFMP
PITKGVSINSLLAFGDIEGIKLLILLLIIILVGFGASTAYLIPWSLLPDAIDQDPEKPSGIYTAWMVFIQKIGIGLSVQF
LGVLLSLSGYKSSTNCLSSLEDLDQPLTAIITIRLCMGLIPSLLVIAGLITMKPWRSLDFKSRRLSQ

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=490, Percent_Identity=21.8367346938776, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI122937339, Length=460, Percent_Identity=21.7391304347826, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1786466, Length=469, Percent_Identity=24.9466950959488, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082306, Length=413, Percent_Identity=24.2130750605327, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI48994989, Length=466, Percent_Identity=22.9613733905579, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790561, Length=167, Percent_Identity=30.5389221556886, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787902, Length=144, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI145693206, Length=466, Percent_Identity=22.7467811158798, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51296; Mature: 51296

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSTSIYEGNNRTRLMISYAMGDAGTGLAAIQLGTYLFLFFTCAAGIPAFIAGSLLMVS
CCCCCCEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLWDAINDPLIGWMSDRTRSRWGPRLPWMIGGAVPLGLFLAAMWWVPPGDIDAKTTYYVF
HHHHHHCCCCEEHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AAIFLMTAYTAVNLPFAALSTELTENIAIRTRLNAARFTGSIIAGTTGLIVAAGFLSQGV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCHHHHCCHHHHCCHHHHHHHHHHHHCH
EGYTSMGRVTGVIATFTTLIACWGLAPFAKKARKPTSQSEPFNQQLKRVLNNKLFTRIIA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LYLLLWCGLQLMQTVSLIYLEQVMLVPIEISKWIPIPFQISTLLGLQFWSFYSNKYGRIS
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
ALFKGGKIWILACFLVIFMPPITKGVSINSLLAFGDIEGIKLLILLLIIILVGFGASTAY
EEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEE
LIPWSLLPDAIDQDPEKPSGIYTAWMVFIQKIGIGLSVQFLGVLLSLSGYKSSTNCLSSL
EEEHHHCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH
EDLDQPLTAIITIRLCMGLIPSLLVIAGLITMKPWRSLDFKSRRLSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MNNSTSIYEGNNRTRLMISYAMGDAGTGLAAIQLGTYLFLFFTCAAGIPAFIAGSLLMVS
CCCCCCEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
KLWDAINDPLIGWMSDRTRSRWGPRLPWMIGGAVPLGLFLAAMWWVPPGDIDAKTTYYVF
HHHHHHCCCCEEHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHH
AAIFLMTAYTAVNLPFAALSTELTENIAIRTRLNAARFTGSIIAGTTGLIVAAGFLSQGV
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCHHHHCCHHHHCCHHHHHHHHHHHHCH
EGYTSMGRVTGVIATFTTLIACWGLAPFAKKARKPTSQSEPFNQQLKRVLNNKLFTRIIA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LYLLLWCGLQLMQTVSLIYLEQVMLVPIEISKWIPIPFQISTLLGLQFWSFYSNKYGRIS
HHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEE
ALFKGGKIWILACFLVIFMPPITKGVSINSLLAFGDIEGIKLLILLLIIILVGFGASTAY
EEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEE
LIPWSLLPDAIDQDPEKPSGIYTAWMVFIQKIGIGLSVQFLGVLLSLSGYKSSTNCLSSL
EEEHHHCCHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH
EDLDQPLTAIITIRLCMGLIPSLLVIAGLITMKPWRSLDFKSRRLSQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]