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The map label for this gene is cysQ [H]

Identifier: 124026372

GI number: 124026372

Start: 1358877

End: 1359791

Strand: Reverse

Name: cysQ [H]

Synonym: NATL1_16661

Alternate gene names: 124026372

Gene position: 1359791-1358877 (Counterclockwise)

Preceding gene: 124026375

Following gene: 124026359

Centisome position: 72.92

GC content: 37.16

Gene sequence:

>915_bases
ATGTCTATTGATCTTGTTGTGCCAAAAGAGGTCGAATTACCGACTTTATTGGATGTGCTTAGAAAGCTTAGCTGGGCTTC
CGCTGATGTTTTGATGGCATATGCAAGAGGTGATGAACCTCCATATGGCTTCCCTAAATCATTAACTGTAGAGGAAGGCG
GTGACGGCCCAGTATCTGCAGCTGACATGGCAGTGAATGAATTATTGATCTCTGGATTGAAGGATAATCTCGCTTTCAAA
GAATGGGATATTTTAAGCGAAGAAACTTCTAAGGAGAAAACTTTTCAGCAAGATAATTATAAAAAAGATTGGTGTTGGAT
TCTTGATCCATTAGATGGGACAAAGGATTTTCTTCAAGGATCTGAAAACTATGCAGTTCATATTGCTTTGGCGTACAAAA
AAAAGCCAAAAATTGGGATAGTTTTGATACCTGAAAAGAATGAATTATGGTTTGGAATTGTTGGAATTGGTGCATGGTTT
GAAAATCGTGATGGCTCTAAAAACCACTTTTCTTTTAGTGATAGATTGGATATTTCGAAATTGATACTAGTTTCAAGTAA
AAATCATCAACAATCAAAACTTAATAACCTTCTGTCAACTCTGTGCTTTGGTGAGACAAAAAAAATAGGCAGTGTCGGTT
GTAAAGTTGTCTCAATTTTGAGGGGAGAAGCAGATGTTTATATCTCTCTATCTGGAAAAACTTCACCCAAGGATTGGGAT
ATGGCTGCTCCGCATGCTCTTATTGAGGCGGCTGGTGGTATGTTCTCTCATGCAGATGGAAAAAATTTAATTTACCAAGA
AACAAACTATTCTCAATCTGGTTGTTTAATTGCAAGCCATGGGAAATCTCATCAAAAGATTTGCCAAAAAGCTATGGATT
TTTTCTCTCTGGAAGAACCTAAATACTTCGTCTAA

Upstream 100 bases:

>100_bases
ATCGCCTAAGTTACCTATTGGCGTACCCACTAGGTAAAGAGTCCCTGGACAAGGTTCTGATCTTTCTTGTTGAAGTTGAT
TTTCATCAATTAAATCCATT

Downstream 100 bases:

>100_bases
TTATTAAGTAAGAGGGGCAACAGGAGTAGGAGTTGGCTCAGGGTAATTGCTCATTCCACCATTTTGAGAGACTCCTCTCA
AAGTTAAATTAATACGTCCA

Product: CysQ

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSIDLVVPKEVELPTLLDVLRKLSWASADVLMAYARGDEPPYGFPKSLTVEEGGDGPVSAADMAVNELLISGLKDNLAFK
EWDILSEETSKEKTFQQDNYKKDWCWILDPLDGTKDFLQGSENYAVHIALAYKKKPKIGIVLIPEKNELWFGIVGIGAWF
ENRDGSKNHFSFSDRLDISKLILVSSKNHQQSKLNNLLSTLCFGETKKIGSVGCKVVSILRGEADVYISLSGKTSPKDWD
MAAPHALIEAAGGMFSHADGKNLIYQETNYSQSGCLIASHGKSHQKICQKAMDFFSLEEPKYFV

Sequences:

>Translated_304_residues
MSIDLVVPKEVELPTLLDVLRKLSWASADVLMAYARGDEPPYGFPKSLTVEEGGDGPVSAADMAVNELLISGLKDNLAFK
EWDILSEETSKEKTFQQDNYKKDWCWILDPLDGTKDFLQGSENYAVHIALAYKKKPKIGIVLIPEKNELWFGIVGIGAWF
ENRDGSKNHFSFSDRLDISKLILVSSKNHQQSKLNNLLSTLCFGETKKIGSVGCKVVSILRGEADVYISLSGKTSPKDWD
MAAPHALIEAAGGMFSHADGKNLIYQETNYSQSGCLIASHGKSHQKICQKAMDFFSLEEPKYFV
>Mature_303_residues
SIDLVVPKEVELPTLLDVLRKLSWASADVLMAYARGDEPPYGFPKSLTVEEGGDGPVSAADMAVNELLISGLKDNLAFKE
WDILSEETSKEKTFQQDNYKKDWCWILDPLDGTKDFLQGSENYAVHIALAYKKKPKIGIVLIPEKNELWFGIVGIGAWFE
NRDGSKNHFSFSDRLDISKLILVSSKNHQQSKLNNLLSTLCFGETKKIGSVGCKVVSILRGEADVYISLSGKTSPKDWDM
AAPHALIEAAGGMFSHADGKNLIYQETNYSQSGCLIASHGKSHQKICQKAMDFFSLEEPKYFV

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI116812595, Length=175, Percent_Identity=26.2857142857143, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031789, Length=213, Percent_Identity=27.2300469483568, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI221625487, Length=213, Percent_Identity=27.2300469483568, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790659, Length=212, Percent_Identity=28.3018867924528, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788882, Length=251, Percent_Identity=23.9043824701195, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193202572, Length=214, Percent_Identity=30.8411214953271, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=226, Percent_Identity=29.646017699115, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651149, Length=273, Percent_Identity=24.5421245421245, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24664922, Length=214, Percent_Identity=27.1028037383178, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 33761; Mature: 33630

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIDLVVPKEVELPTLLDVLRKLSWASADVLMAYARGDEPPYGFPKSLTVEEGGDGPVSA
CCEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCEEEECCCCCCCHH
ADMAVNELLISGLKDNLAFKEWDILSEETSKEKTFQQDNYKKDWCWILDPLDGTKDFLQG
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCC
SENYAVHIALAYKKKPKIGIVLIPEKNELWFGIVGIGAWFENRDGSKNHFSFSDRLDISK
CCCEEEEEEEEECCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEE
LILVSSKNHQQSKLNNLLSTLCFGETKKIGSVGCKVVSILRGEADVYISLSGKTSPKDWD
EEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
MAAPHALIEAAGGMFSHADGKNLIYQETNYSQSGCLIASHGKSHQKICQKAMDFFSLEEP
CCCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCC
KYFV
CCCC
>Mature Secondary Structure 
SIDLVVPKEVELPTLLDVLRKLSWASADVLMAYARGDEPPYGFPKSLTVEEGGDGPVSA
CEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCCEEEECCCCCCCHH
ADMAVNELLISGLKDNLAFKEWDILSEETSKEKTFQQDNYKKDWCWILDPLDGTKDFLQG
HHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHCC
SENYAVHIALAYKKKPKIGIVLIPEKNELWFGIVGIGAWFENRDGSKNHFSFSDRLDISK
CCCEEEEEEEEECCCCCEEEEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCEE
LILVSSKNHQQSKLNNLLSTLCFGETKKIGSVGCKVVSILRGEADVYISLSGKTSPKDWD
EEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
MAAPHALIEAAGGMFSHADGKNLIYQETNYSQSGCLIASHGKSHQKICQKAMDFFSLEEP
CCCCHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCC
KYFV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]