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The map label for this gene is glyQ

Identifier: 124026328

GI number: 124026328

Start: 1325835

End: 1326707

Strand: Reverse

Name: glyQ

Synonym: NATL1_16221

Alternate gene names: 124026328

Gene position: 1326707-1325835 (Counterclockwise)

Preceding gene: 124026329

Following gene: 124026327

Centisome position: 71.15

GC content: 39.63

Gene sequence:

>873_bases
ATGTATTTTCAGGACATAATTTCTAACCTCAATAATTTCTGGAGTGAGAAGGGTTGTTTGCTGCTTCAGCCATATGATTT
AGAGAAGGGCGCAGGGACGATGAGCCCTCATTCTTTTTTAAGAGCGATAGGTCCTGAGCCTTGGGCTGTGGCTTACCCCG
AGCCCTGTCGGCGTCCGACTGATGGTAGGTATGGAGACAATCCAAATAGAGCACAGCATTATTTTCAATATCAAGTTCTT
ATAAAGCCCTCTTTAGACGGTATACAAGAAATTTATTTATCTTCTCTTGAGGCCTTGGGGATTTCAGCTAAGGAGCACGA
TATTAGATTCGTTGAAGATAATTGGGAATCTCCAACTTTAGGGGCATGGGGAGTGGGTTGGGAAGTTTGGCTTGATGGGA
TGGAAGTTACCCAATTTACTTATTTTCAACAATGTGGAGGTCTTGATTGCAAGCCTGTTTCGATTGAGATCACTTATGGC
TTGGAGAGATTGGCAATGTATCTGCAAAATGTTGAAAGTATTTGGGACCTTTCCTGGAATAAAAAGACTAAATATGGTGA
TATCTGGCTTCCTTTTGAGAAAGGTCAATGTAAGTATAATTTTGAAGAATCTAACTCGGAAAATTTAAGGAAACTTTTTG
AAATTTACGAAGAAGAGGCTCATCAATTAATCGCTAAAAAACTACCTGCACCTTGTCTTGATTACGTTTTAAAATGCAGT
CATACATTTAATTTATTGGAAGCAAGAGGGGTAATTTCTGTTACTGAGAGAACTAAGATTATTGCAAGAATTCGATCTTT
AGCTCGTAAGGTTGCTGAAGCTTGGCTAGAGGAAAGAGGTACCCTTGGCTTCCCTCTTTGTGCAGAAAATTAG

Upstream 100 bases:

>100_bases
TTTAGAGATTCTGTTTTATTATTATTATTTTGTTATTTAAGTGTATATTTATAAGTGAACTAATAAATTCAAATTTTCAT
CATTAAATAATTTATTTTAT

Downstream 100 bases:

>100_bases
TTAACTCTAAGTAATAATTTTAGATTAATTCGCTAACAAATAGTTCGAATAATATATCTCGCTGTATAAAAAGATACTTC
TAAGAACTTTCGCCCTGAAA

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MYFQDIISNLNNFWSEKGCLLLQPYDLEKGAGTMSPHSFLRAIGPEPWAVAYPEPCRRPTDGRYGDNPNRAQHYFQYQVL
IKPSLDGIQEIYLSSLEALGISAKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYG
LERLAMYLQNVESIWDLSWNKKTKYGDIWLPFEKGQCKYNFEESNSENLRKLFEIYEEEAHQLIAKKLPAPCLDYVLKCS
HTFNLLEARGVISVTERTKIIARIRSLARKVAEAWLEERGTLGFPLCAEN

Sequences:

>Translated_290_residues
MYFQDIISNLNNFWSEKGCLLLQPYDLEKGAGTMSPHSFLRAIGPEPWAVAYPEPCRRPTDGRYGDNPNRAQHYFQYQVL
IKPSLDGIQEIYLSSLEALGISAKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYG
LERLAMYLQNVESIWDLSWNKKTKYGDIWLPFEKGQCKYNFEESNSENLRKLFEIYEEEAHQLIAKKLPAPCLDYVLKCS
HTFNLLEARGVISVTERTKIIARIRSLARKVAEAWLEERGTLGFPLCAEN
>Mature_290_residues
MYFQDIISNLNNFWSEKGCLLLQPYDLEKGAGTMSPHSFLRAIGPEPWAVAYPEPCRRPTDGRYGDNPNRAQHYFQYQVL
IKPSLDGIQEIYLSSLEALGISAKEHDIRFVEDNWESPTLGAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYG
LERLAMYLQNVESIWDLSWNKKTKYGDIWLPFEKGQCKYNFEESNSENLRKLFEIYEEEAHQLIAKKLPAPCLDYVLKCS
HTFNLLEARGVISVTERTKIIARIRSLARKVAEAWLEERGTLGFPLCAEN

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=294, Percent_Identity=59.1836734693878, Blast_Score=367, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_PROM1 (A2C3W9)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001015444.1
- ProteinModelPortal:   A2C3W9
- SMR:   A2C3W9
- STRING:   A2C3W9
- GeneID:   4780063
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_16221
- eggNOG:   COG0752
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   PMAR167555:NATL1_16221-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 33425; Mature: 33425

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFQDIISNLNNFWSEKGCLLLQPYDLEKGAGTMSPHSFLRAIGPEPWAVAYPEPCRRPT
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEECCCHHCCCCC
DGRYGDNPNRAQHYFQYQVLIKPSLDGIQEIYLSSLEALGISAKEHDIRFVEDNWESPTL
CCCCCCCCCHHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYGLERLAMYLQNVESIWDLSWN
CCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCC
KKTKYGDIWLPFEKGQCKYNFEESNSENLRKLFEIYEEEAHQLIAKKLPAPCLDYVLKCS
CCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HTFNLLEARGVISVTERTKIIARIRSLARKVAEAWLEERGTLGFPLCAEN
HHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MYFQDIISNLNNFWSEKGCLLLQPYDLEKGAGTMSPHSFLRAIGPEPWAVAYPEPCRRPT
CCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCEECCCHHCCCCC
DGRYGDNPNRAQHYFQYQVLIKPSLDGIQEIYLSSLEALGISAKEHDIRFVEDNWESPTL
CCCCCCCCCHHHHEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCC
GAWGVGWEVWLDGMEVTQFTYFQQCGGLDCKPVSIEITYGLERLAMYLQNVESIWDLSWN
CCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCC
KKTKYGDIWLPFEKGQCKYNFEESNSENLRKLFEIYEEEAHQLIAKKLPAPCLDYVLKCS
CCCCCCCEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HTFNLLEARGVISVTERTKIIARIRSLARKVAEAWLEERGTLGFPLCAEN
HHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA