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The map label for this gene is 124026280

Identifier: 124026280

GI number: 124026280

Start: 1281122

End: 1282666

Strand: Reverse

Name: 124026280

Synonym: NATL1_15741

Alternate gene names: NA

Gene position: 1282666-1281122 (Counterclockwise)

Preceding gene: 124026281

Following gene: 124026277

Centisome position: 68.79

GC content: 27.18

Gene sequence:

>1545_bases
ATGAATAAAAAAAGAAATAAGGCTATTAATCACACAAAAAGAAATCAAGTCAAAACATTTCCTATCTCATTTTCTTTATA
TAAAATCAAAGATGATCTAATAATAAATACAAATTATCTTTCTGAAACTCCAGAAGAAGAAATAATTAATCAAGCAATTA
AGTTTCATTTGCAAGGTAAGATTTCAGAGGCAATAAAATATTATAAGCATTGTCTTATCAAAGGTTTTCATGATGAAAAA
GTTTTTTGTAATTATGGAATTATATTGAAAAATTTGGGTAAAACTAAAGAAGCAGAATTACTACAACTTAAAGCAATAGA
AATAAAACCAAACTATGCAGAAGCTTACTCTAATCTGGGAGTTATATATAAAGATAAAGGTAAGTTAAAGGAAGCTGAAT
TATCACTTAAGAAAGCTATAGAAATAAGACCTAATTTTGCAAATGCTCATAATAATCTGGGTATTATATTCAATGATCTG
GGGAAATTTAAAGAAGCTGAGTTATCTTATTTGAAAGCGATAGAATTAAAACCAGATTTTGCAGAACCATATTATTCTTT
ATCACTTCTCAACTGCTCAAATGAAAATAAATTTTGGCAGAATAGACTTTTTTCTAAAAGTATACTAAATAATAAATCAA
AAAAAGAGAAGATTGATATTTATTTCGCTAGGTCGAATGTTTTACATAAAGAGAAAAATTATATAGAAAGTTCTCACTAT
CTAAATTTAGCTAATCGGATCAAACTTAATCTTAGACCATCAAATATTAATCTTCGTTTAGAAAAATCTAAAAGATTGCT
TTTAGAATCAGATAAAAGAGAAACCAATAAAAAAGAAGATATAAAAACTATTAAAACAATTTTTATTGTTGGCATGCCTA
GAAGCGGATCAACATTACTTGAATCAATAATTAGTATGAATCCTAATGTCGATAGCTTAGGGGAAATTAATTTTCTGGAG
GAGTCATTCTTAGAGGAAGAACATAATGAACAAGGATTGAATCTTGCTGAATTATATTTGGAAAAGATTAATGTTAACAG
TACTAGATCAACTATTAAAACTAACAAGTATTTATATAACTATCAGTATGCAGGTATTATTGCAACTTGCATCCCTAATA
GTAAAATTATTCACTGCTTTAGAAATCCTTTAGATAATATATTATCTATATATCGAGCACATTTTACTATAGGTAACGAA
TACTCTTCTTCCTTAGCAGATTGTGCAAATATATATTTAGATCAAGAAGAAATAATGGATATTTATAAAAAAAAATATAG
ATCAAATATTTATGATCTCAACTATGACTTATTGGTTAGCAATCCTCAGGAAGAAATTATCTCATTAATTTCATGGTTGG
GATGGGAATGGGATGATTCATATCTATCGCACCATTTAAATCCACGTTCAATTTCAACAGCAAGTAGCGTTCAAGTCCGT
TCTCCTATTAATTCGAAATCCATTGGAGGGTGGAAGAACTACAGAGATATGTTAAAACCTGTTATTGAAATATTAGAAAA
GCATGAGAAATATAAAAATTTATAA

Upstream 100 bases:

>100_bases
CTGAAGAAAAAATTATTAACCTAGCAATAAAAGTTCATTTAGATGATAAGCTTTTGAAAGCCGGATGTACTTTTAAAACC
TTGCATCTTTTAAGAGGTCT

Downstream 100 bases:

>100_bases
TTCTAATAATGCAAGAATTATTTCTTTCTTTACGACCATAGTAGATTATTTTACTACTCAATTTAAACCCTTTGATTTAC
CAAGCCTGTTAATCTATGTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MNKKRNKAINHTKRNQVKTFPISFSLYKIKDDLIINTNYLSETPEEEIINQAIKFHLQGKISEAIKYYKHCLIKGFHDEK
VFCNYGIILKNLGKTKEAELLQLKAIEIKPNYAEAYSNLGVIYKDKGKLKEAELSLKKAIEIRPNFANAHNNLGIIFNDL
GKFKEAELSYLKAIELKPDFAEPYYSLSLLNCSNENKFWQNRLFSKSILNNKSKKEKIDIYFARSNVLHKEKNYIESSHY
LNLANRIKLNLRPSNINLRLEKSKRLLLESDKRETNKKEDIKTIKTIFIVGMPRSGSTLLESIISMNPNVDSLGEINFLE
ESFLEEEHNEQGLNLAELYLEKINVNSTRSTIKTNKYLYNYQYAGIIATCIPNSKIIHCFRNPLDNILSIYRAHFTIGNE
YSSSLADCANIYLDQEEIMDIYKKKYRSNIYDLNYDLLVSNPQEEIISLISWLGWEWDDSYLSHHLNPRSISTASSVQVR
SPINSKSIGGWKNYRDMLKPVIEILEKHEKYKNL

Sequences:

>Translated_514_residues
MNKKRNKAINHTKRNQVKTFPISFSLYKIKDDLIINTNYLSETPEEEIINQAIKFHLQGKISEAIKYYKHCLIKGFHDEK
VFCNYGIILKNLGKTKEAELLQLKAIEIKPNYAEAYSNLGVIYKDKGKLKEAELSLKKAIEIRPNFANAHNNLGIIFNDL
GKFKEAELSYLKAIELKPDFAEPYYSLSLLNCSNENKFWQNRLFSKSILNNKSKKEKIDIYFARSNVLHKEKNYIESSHY
LNLANRIKLNLRPSNINLRLEKSKRLLLESDKRETNKKEDIKTIKTIFIVGMPRSGSTLLESIISMNPNVDSLGEINFLE
ESFLEEEHNEQGLNLAELYLEKINVNSTRSTIKTNKYLYNYQYAGIIATCIPNSKIIHCFRNPLDNILSIYRAHFTIGNE
YSSSLADCANIYLDQEEIMDIYKKKYRSNIYDLNYDLLVSNPQEEIISLISWLGWEWDDSYLSHHLNPRSISTASSVQVR
SPINSKSIGGWKNYRDMLKPVIEILEKHEKYKNL
>Mature_514_residues
MNKKRNKAINHTKRNQVKTFPISFSLYKIKDDLIINTNYLSETPEEEIINQAIKFHLQGKISEAIKYYKHCLIKGFHDEK
VFCNYGIILKNLGKTKEAELLQLKAIEIKPNYAEAYSNLGVIYKDKGKLKEAELSLKKAIEIRPNFANAHNNLGIIFNDL
GKFKEAELSYLKAIELKPDFAEPYYSLSLLNCSNENKFWQNRLFSKSILNNKSKKEKIDIYFARSNVLHKEKNYIESSHY
LNLANRIKLNLRPSNINLRLEKSKRLLLESDKRETNKKEDIKTIKTIFIVGMPRSGSTLLESIISMNPNVDSLGEINFLE
ESFLEEEHNEQGLNLAELYLEKINVNSTRSTIKTNKYLYNYQYAGIIATCIPNSKIIHCFRNPLDNILSIYRAHFTIGNE
YSSSLADCANIYLDQEEIMDIYKKKYRSNIYDLNYDLLVSNPQEEIISLISWLGWEWDDSYLSHHLNPRSISTASSVQVR
SPINSKSIGGWKNYRDMLKPVIEILEKHEKYKNL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307150, Length=131, Percent_Identity=38.1679389312977, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI32307148, Length=131, Percent_Identity=38.1679389312977, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI118766330, Length=113, Percent_Identity=38.9380530973451, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI118766328, Length=113, Percent_Identity=38.9380530973451, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI115532692, Length=139, Percent_Identity=37.410071942446, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI115532690, Length=139, Percent_Identity=37.410071942446, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25147174, Length=113, Percent_Identity=37.1681415929204, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17647755, Length=132, Percent_Identity=40.1515151515151, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24585827, Length=132, Percent_Identity=40.1515151515151, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24585829, Length=132, Percent_Identity=40.1515151515151, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24647123, Length=194, Percent_Identity=29.3814432989691, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000863
- InterPro:   IPR001440
- InterPro:   IPR011717
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00685 Sulfotransfer_1; PF00515 TPR_1; PF07721 TPR_4 [H]

EC number: NA

Molecular weight: Translated: 59814; Mature: 59814

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKRNKAINHTKRNQVKTFPISFSLYKIKDDLIINTNYLSETPEEEIINQAIKFHLQGK
CCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHCCC
ISEAIKYYKHCLIKGFHDEKVFCNYGIILKNLGKTKEAELLQLKAIEIKPNYAEAYSNLG
HHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHCCC
VIYKDKGKLKEAELSLKKAIEIRPNFANAHNNLGIIFNDLGKFKEAELSYLKAIELKPDF
EEEECCCCCHHHHHHHHHHHEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHEECCCCC
AEPYYSLSLLNCSNENKFWQNRLFSKSILNNKSKKEKIDIYFARSNVLHKEKNYIESSHY
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCHHH
LNLANRIKLNLRPSNINLRLEKSKRLLLESDKRETNKKEDIKTIKTIFIVGMPRSGSTLL
EEECCEEEEEEECCCEEEEEECCCCHHHCCCCHHCCHHHHHHHEEEEEEEECCCCCHHHH
ESIISMNPNVDSLGEINFLEESFLEEEHNEQGLNLAELYLEKINVNSTRSTIKTNKYLYN
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHCCCCEEEE
YQYAGIIATCIPNSKIIHCFRNPLDNILSIYRAHFTIGNEYSSSLADCANIYLDQEEIMD
EEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHEECHHHHHH
IYKKKYRSNIYDLNYDLLVSNPQEEIISLISWLGWEWDDSYLSHHLNPRSISTASSVQVR
HHHHHHHCCCEECCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEE
SPINSKSIGGWKNYRDMLKPVIEILEKHEKYKNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKKRNKAINHTKRNQVKTFPISFSLYKIKDDLIINTNYLSETPEEEIINQAIKFHLQGK
CCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCEEEECCCCCCCCHHHHHHHHHHHHHCCC
ISEAIKYYKHCLIKGFHDEKVFCNYGIILKNLGKTKEAELLQLKAIEIKPNYAEAYSNLG
HHHHHHHHHHHHHCCCCCCEEEEECCHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHCCC
VIYKDKGKLKEAELSLKKAIEIRPNFANAHNNLGIIFNDLGKFKEAELSYLKAIELKPDF
EEEECCCCCHHHHHHHHHHHEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHEECCCCC
AEPYYSLSLLNCSNENKFWQNRLFSKSILNNKSKKEKIDIYFARSNVLHKEKNYIESSHY
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHCCHHH
LNLANRIKLNLRPSNINLRLEKSKRLLLESDKRETNKKEDIKTIKTIFIVGMPRSGSTLL
EEECCEEEEEEECCCEEEEEECCCCHHHCCCCHHCCHHHHHHHEEEEEEEECCCCCHHHH
ESIISMNPNVDSLGEINFLEESFLEEEHNEQGLNLAELYLEKINVNSTRSTIKTNKYLYN
HHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHCCCCEEEE
YQYAGIIATCIPNSKIIHCFRNPLDNILSIYRAHFTIGNEYSSSLADCANIYLDQEEIMD
EEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHEECHHHHHH
IYKKKYRSNIYDLNYDLLVSNPQEEIISLISWLGWEWDDSYLSHHLNPRSISTASSVQVR
HHHHHHHCCCEECCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCEEEE
SPINSKSIGGWKNYRDMLKPVIEILEKHEKYKNL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]