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The map label for this gene is clpC [H]

Identifier: 124026198

GI number: 124026198

Start: 1202270

End: 1204837

Strand: Direct

Name: clpC [H]

Synonym: NATL1_14921

Alternate gene names: 124026198

Gene position: 1202270-1204837 (Clockwise)

Preceding gene: 124026197

Following gene: 124026199

Centisome position: 64.47

GC content: 37.31

Gene sequence:

>2568_bases
ATGTTTGAGAGGTTTACAGAAAAGGCTATAAAAGTGATCATGCTTGCTCAAGAAGAGGCAAGACGCCTTGGGCATAATTT
CGTCGGAACAGAACAAATCCTTCTTGGACTAATTGGTGAAGGTACTGGCGTAGCAGCTAAAGTTCTTAAATCAATGGGTG
TCAACCTAAAAGATTCAAGAGTAGAAGTTGAAAAGATAATAGGAAGAGGCTCAGGATTCGTTGCCGTAGAAATTCCCTTC
ACACCAAGAGCAAAAAGAGTACTTGAACTTTCATTAGAAGAAGCTCGTCAACTTGGTCACAATTACATTGGTACTGAACA
TCTATTACTTGGTCTAATAAGAGAAGGTGAAGGAGTAGCGGCAAGAGTTCTAGAAAATTTAGGCGTTGATCTCACAAAAG
TCAGGACCCAAGTTGTCAGAATGCTTGGTGAAACTGCAGAAGTTACAACAGGATCAGGTTCATCTAAAGGATCAGCAAAA
ACAGCAACACTTGACGAATTTGGAACAAACCTAACTCAGCTAGCTAGTGAATCAAAGCTTGACCCAGTAGTGGGCAGACA
TTCAGAGATTGATCGTGTAATTCAAATACTTGGAAGAAGAACAAAAAACAATCCTGTTTTAATTGGAGAGCCAGGAGTAG
GGAAAACTGCCATAGCCGAAGGACTTGCTCAGAGAATTCAACAAGGAAATATTCCTGACATACTTGAGGAGAAGAGAGTA
TTGACCCTTGATATTGGTTTACTTGTTGCAGGCACCAAATATAGAGGTGAATTTGAAGAAAGACTAAAGAAAATAATGGA
AGAGATCAAATCAGCTGGAAATGTAATTCTAGTTATTGATGAAGTTCATACCTTGATAGGCGCAGGTGCTGCTGAGGGAG
CAATTGACGCTGCAAACATTTTAAAACCTGCTTTAGCAAGAGGAGAACTCCAATGTATTGGAGCTACAACTCTTGATGAA
TATCGCAAACATATTGAAAGAGATGCTGCATTAGAGCGAAGATTCCAACCTGTAATGATTGGAGAACCTTCAATTAAAGA
CACTATCGAAATACTTAAAGGATTAAGAGAGAGATATGAACAACATCACAGATTAAAGATTACGGATGAAGCTCTTGATG
CTGCTGCTAATCTTGGTGATAGGTATATTTCTGATCGTTTTTTACCTGATAAAGCTATAGACCTTATAGATGAAGCAGGA
AGCCGAGTCAGATTACTCAACTCCAAATTGCCTCCTGAAGCAAAAGAAGTTGATAAAGAATTAAGAAAAATACAAAAGAG
TAAAGAAGAAGCTGTAAGAGATCAAAATTTCACCCAAGCAGGAGAGCTCAGAGAAAAAGAAGTTGAGCTTAGAGATAAGA
TAAGAAATCTTTTGCAAAATATAAGACAAAAACCATCATCAAATGAAAATCCCGATTCAAATAATGTTCCACAGGAAAAT
AATCAAGCTTCCGACCAAGTTATTAATCAATCCGACGACTTAAAAGTTTCCCAACCGGTAGTTAACGAAGAAGACATTGC
TCATATTGTTGCTTCATGGACTGGCGTTCCTGTTCAGAAATTAACTGAAAGTGAATCAGTCAAACTTCTAAATATGGAAG
ATACATTGCATCAGAGACTGATTGGTCAAGACGAAGCTGTAAAAGCTGTTTCAAAAGCAATTAGGAGAGCAAGAGTAGGC
CTAAAGAATCCAAACAGACCAATTGCTAGCTTTATTTTTTCTGGTCCAACGGGAGTTGGAAAAACTGAATTAACTAAAGC
TTTAGCAGCCTATTTCTTTGGTAGTGAAGAAGCAATGATACGTTTAGACATGTCTGAATTCATGGAAAGACATACTGTTA
GTAAATTAATAGGTTCTCCTCCAGGCTACGTAGGTTTCAATGAAGGTGGACAACTAACAGAAGCCGTAAGAAGAAGACCC
TATACAGTAGTTTTGTTCGATGAAATAGAAAAAGCTCATCCAGATGTGTTCAATCTTCTCCTTCAATTACTGGAAGAAGG
AAGATTAACAGACTCAAAAGGAAGAACTGTTGATTTCAAAAATACTCTAATAATAATGACCTCTAATATTGGATCTAAAG
TTATAGAGAAAGGCGGAGGCGGATTGGGATTTGAATTCTCTGGTGAAAATTTAGAAGATACTCAATATAATCGAATTAAA
TCATTAGTAAATGAAGAACTAAAACAATATTTCCGCCCTGAATTCCTCAATAGATTAGATGAAATAATTGTATTTAGACA
GCTTTCCAGAGACGAAGTCAAAGACATCGCAGAAATAATGTTGAAAGAAGTATTCTCGAGAATAAAAGATAAAGGGATAT
CATTAACTGTTTCAGAGGATTTCAAAGAAAGATTAGTTGAAGAAGGATACAATCCTTCTTATGGTGCAAGGCCTTTAAGA
AGAGCGGTCATGAGGTTATTGGAAGATAGCCTTGCCGAAGAAGTTTTATCAGGAAGGATAAAAGACGGAGACAAAGCGGA
GGTGGATATTGATGAAAGCAAGAAAGTAATTGTTAAACATCTTGGGAAAGATGGTTCCAAACCAGAATTAGCAAGCGCCA
CTGTTTAA

Upstream 100 bases:

>100_bases
CGAACACTTAATATTTACCCTTTATAAAAAAAACCCTAACCGTACACATTTCACACTTAACCCTGATAAATTAGGTTAAA
TAGTTAAAGGCTAAAGCTAA

Downstream 100 bases:

>100_bases
CTTTTAAATAGAAAAGTTATATGTTTATAAATAATCACTGCATTTCACCTTCAAATGTCGTTAGAGGTGAAGGAGCATGG
GGTGACTCATTAGATCTAAT

Product: ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 855; Mature: 855

Protein sequence:

>855_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDSRVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLTKVRTQVVRMLGETAEVTTGSGSSKGSAK
TATLDEFGTNLTQLASESKLDPVVGRHSEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGNIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMIGEPSIKDTIEILKGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPEAKEVDKELRKIQKSKEEAVRDQNFTQAGELREKEVELRDKIRNLLQNIRQKPSSNENPDSNNVPQEN
NQASDQVINQSDDLKVSQPVVNEEDIAHIVASWTGVPVQKLTESESVKLLNMEDTLHQRLIGQDEAVKAVSKAIRRARVG
LKNPNRPIASFIFSGPTGVGKTELTKALAAYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRP
YTVVLFDEIEKAHPDVFNLLLQLLEEGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENLEDTQYNRIK
SLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKDIAEIMLKEVFSRIKDKGISLTVSEDFKERLVEEGYNPSYGARPLR
RAVMRLLEDSLAEEVLSGRIKDGDKAEVDIDESKKVIVKHLGKDGSKPELASATV

Sequences:

>Translated_855_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDSRVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLTKVRTQVVRMLGETAEVTTGSGSSKGSAK
TATLDEFGTNLTQLASESKLDPVVGRHSEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGNIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMIGEPSIKDTIEILKGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPEAKEVDKELRKIQKSKEEAVRDQNFTQAGELREKEVELRDKIRNLLQNIRQKPSSNENPDSNNVPQEN
NQASDQVINQSDDLKVSQPVVNEEDIAHIVASWTGVPVQKLTESESVKLLNMEDTLHQRLIGQDEAVKAVSKAIRRARVG
LKNPNRPIASFIFSGPTGVGKTELTKALAAYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRP
YTVVLFDEIEKAHPDVFNLLLQLLEEGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENLEDTQYNRIK
SLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKDIAEIMLKEVFSRIKDKGISLTVSEDFKERLVEEGYNPSYGARPLR
RAVMRLLEDSLAEEVLSGRIKDGDKAEVDIDESKKVIVKHLGKDGSKPELASATV
>Mature_855_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDSRVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLTKVRTQVVRMLGETAEVTTGSGSSKGSAK
TATLDEFGTNLTQLASESKLDPVVGRHSEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGNIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMIGEPSIKDTIEILKGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPEAKEVDKELRKIQKSKEEAVRDQNFTQAGELREKEVELRDKIRNLLQNIRQKPSSNENPDSNNVPQEN
NQASDQVINQSDDLKVSQPVVNEEDIAHIVASWTGVPVQKLTESESVKLLNMEDTLHQRLIGQDEAVKAVSKAIRRARVG
LKNPNRPIASFIFSGPTGVGKTELTKALAAYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRP
YTVVLFDEIEKAHPDVFNLLLQLLEEGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENLEDTQYNRIK
SLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKDIAEIMLKEVFSRIKDKGISLTVSEDFKERLVEEGYNPSYGARPLR
RAVMRLLEDSLAEEVLSGRIKDGDKAEVDIDESKKVIVKHLGKDGSKPELASATV

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=339, Percent_Identity=39.5280235988201, Blast_Score=215, Evalue=1e-55,
Organism=Escherichia coli, GI1788943, Length=878, Percent_Identity=45.2164009111617, Blast_Score=738, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=407, Percent_Identity=42.014742014742, Blast_Score=299, Evalue=6e-82,
Organism=Saccharomyces cerevisiae, GI6320464, Length=716, Percent_Identity=47.9050279329609, Blast_Score=639, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=903, Percent_Identity=35.8803986710963, Blast_Score=539, Evalue=1e-154,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 94924; Mature: 94924

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50151 UVR ; PS00036 BZIP_BASIC ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHH
VEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLTKVRTQVVRMLGETAEVTTGSGSSKGSAKTATLDEFGTNLTQLASESKL
HHHHHHHCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHCCCHHHHHHHCCC
DPVVGRHSEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGNIPDILEEKRV
CCHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMIGEPSIKDTIEILKGLRERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAGSRVRLLNSKLPPEAKEVDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHH
LRKIQKSKEEAVRDQNFTQAGELREKEVELRDKIRNLLQNIRQKPSSNENPDSNNVPQEN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NQASDQVINQSDDLKVSQPVVNEEDIAHIVASWTGVPVQKLTESESVKLLNMEDTLHQRL
CCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHH
IGQDEAVKAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALAAYFFGSEEAMI
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEE
RLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNLL
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHH
LQLLEEGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENLEDTQYNRIK
HHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEEECCCCCCHHHHHHHH
SLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKDIAEIMLKEVFSRIKDKGISLTVSED
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHH
FKERLVEEGYNPSYGARPLRRAVMRLLEDSLAEEVLSGRIKDGDKAEVDIDESKKVIVKH
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHH
LGKDGSKPELASATV
HCCCCCCCCCCCCCC
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMGVNLKDSR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHH
VEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLTKVRTQVVRMLGETAEVTTGSGSSKGSAKTATLDEFGTNLTQLASESKL
HHHHHHHCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCHHHHCCCHHHHHHHCCC
DPVVGRHSEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGNIPDILEEKRV
CCHHCCHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMIGEPSIKDTIEILKGLRERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAGSRVRLLNSKLPPEAKEVDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHHH
LRKIQKSKEEAVRDQNFTQAGELREKEVELRDKIRNLLQNIRQKPSSNENPDSNNVPQEN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NQASDQVINQSDDLKVSQPVVNEEDIAHIVASWTGVPVQKLTESESVKLLNMEDTLHQRL
CCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHCCCCCEEEECHHHHHHHHH
IGQDEAVKAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALAAYFFGSEEAMI
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEE
RLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNLL
EECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHHHHHH
LQLLEEGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENLEDTQYNRIK
HHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEEECCCCCCHHHHHHHH
SLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKDIAEIMLKEVFSRIKDKGISLTVSED
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEECHH
FKERLVEEGYNPSYGARPLRRAVMRLLEDSLAEEVLSGRIKDGDKAEVDIDESKKVIVKH
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHH
LGKDGSKPELASATV
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]