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The map label for this gene is gap3 [H]

Identifier: 124025864

GI number: 124025864

Start: 1033950

End: 1034975

Strand: Reverse

Name: gap3 [H]

Synonym: NATL1_11571

Alternate gene names: 124025864

Gene position: 1034975-1033950 (Counterclockwise)

Preceding gene: 124025869

Following gene: 124025863

Centisome position: 55.5

GC content: 38.11

Gene sequence:

>1026_bases
ATGCGCATTGGTATTAATGGTTTTGGCCGTATAGGACGACTTGTTCTTAGAGCACTCTGGGATAGGGAAAATATCGAGAT
TTCGCATATCAACGATCCATTTGGTGATGCAAAGGGAGCTGCGCATTTACTTGAATATGACTCAGTTCATGGTCGTTGGA
ACAAAGCAATAAGCAACGACCAAAACAACCTGAGTATTGAAGGTCAGCCAATATCTTTTTCTCAAGAAAGTGATTACACA
AAAGTGCCATGGAATGAAAAAGGTATAGAGCTAATTCTCGAATGCTCAGGAAAATTCAAAACTCCTCAAACATTAAATCC
TTATTTTGATACTCTTGGGATGAAAAGAGTTGTCGTTGCATGTCCAGTAAAAGGATCCATCCAGGGAGAGGATACTCTAA
ATATCGTCTACGGTATTAATCATGATTTATATGAGCCCAATAAACATCGCTTAGTAACAGCTGCATCCTGCACAACTAAT
TGCTTAGCTCCCGTTGTGAAAGTTGTTAATCAAGCTTTTGGTATAAAGCATGGAAGCATCACAACACTTCATGATTTAAC
AAATACACAGGTAATTGTTGATTCATTTAAATCAGATTTAAGAAGAGCAAGGAGCGGATCACAAAGCTTAATTCCAACAA
CAACAGGATCAGCAAAAGCGATAGGGATGATATTCCCAGAATTACAAGGAAAATTAAATGGCCATGCAGTTCGAGTCCCT
CTCCTCAATGGATCTTTAACTGATGCTGTATTTGAATTAGAGAAAGAGGTCACGCAAGAAGAAGTTAATCATGTGTTCAA
AGAAGCTTCAGAAGGAGAGCTAAAAGGAATCCTTGGTTACGAAGAAAAACCACTTGTCTCAATTGATTATGTCAATGACT
CAAGGAGTTCAATCATAGATGCGCCATCAACCATGGTGATCAATAAATCTCAATTGAAAGTCTATATTTGGTATGACAAT
GAATGGGGTTATAGCTGTCGAATGGCAGATCTCGTCTGCCATGTCATAAATCTTGAAAAGGATTAA

Upstream 100 bases:

>100_bases
TATTTACTCATAATACAAGAATTTCCAAAGCCAATCAAGAATGATTGATGCATCAACCATTCTTGATATATGCTATGTAT
GTGCCCTGTTGCGGAGTTTT

Downstream 100 bases:

>100_bases
AAATAAGAACATGCGATTATCGGCTTTGCAACAATATGGAATCGTAACGACCAACTATTGGGCATTCACACTGACAGATG
GTGCTCTAAGAATGCTAGTG

Product: putative glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MRIGINGFGRIGRLVLRALWDRENIEISHINDPFGDAKGAAHLLEYDSVHGRWNKAISNDQNNLSIEGQPISFSQESDYT
KVPWNEKGIELILECSGKFKTPQTLNPYFDTLGMKRVVVACPVKGSIQGEDTLNIVYGINHDLYEPNKHRLVTAASCTTN
CLAPVVKVVNQAFGIKHGSITTLHDLTNTQVIVDSFKSDLRRARSGSQSLIPTTTGSAKAIGMIFPELQGKLNGHAVRVP
LLNGSLTDAVFELEKEVTQEEVNHVFKEASEGELKGILGYEEKPLVSIDYVNDSRSSIIDAPSTMVINKSQLKVYIWYDN
EWGYSCRMADLVCHVINLEKD

Sequences:

>Translated_341_residues
MRIGINGFGRIGRLVLRALWDRENIEISHINDPFGDAKGAAHLLEYDSVHGRWNKAISNDQNNLSIEGQPISFSQESDYT
KVPWNEKGIELILECSGKFKTPQTLNPYFDTLGMKRVVVACPVKGSIQGEDTLNIVYGINHDLYEPNKHRLVTAASCTTN
CLAPVVKVVNQAFGIKHGSITTLHDLTNTQVIVDSFKSDLRRARSGSQSLIPTTTGSAKAIGMIFPELQGKLNGHAVRVP
LLNGSLTDAVFELEKEVTQEEVNHVFKEASEGELKGILGYEEKPLVSIDYVNDSRSSIIDAPSTMVINKSQLKVYIWYDN
EWGYSCRMADLVCHVINLEKD
>Mature_341_residues
MRIGINGFGRIGRLVLRALWDRENIEISHINDPFGDAKGAAHLLEYDSVHGRWNKAISNDQNNLSIEGQPISFSQESDYT
KVPWNEKGIELILECSGKFKTPQTLNPYFDTLGMKRVVVACPVKGSIQGEDTLNIVYGINHDLYEPNKHRLVTAASCTTN
CLAPVVKVVNQAFGIKHGSITTLHDLTNTQVIVDSFKSDLRRARSGSQSLIPTTTGSAKAIGMIFPELQGKLNGHAVRVP
LLNGSLTDAVFELEKEVTQEEVNHVFKEASEGELKGILGYEEKPLVSIDYVNDSRSSIIDAPSTMVINKSQLKVYIWYDN
EWGYSCRMADLVCHVINLEKD

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=340, Percent_Identity=42.0588235294118, Blast_Score=282, Evalue=3e-76,
Organism=Homo sapiens, GI7657116, Length=341, Percent_Identity=37.2434017595308, Blast_Score=248, Evalue=6e-66,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=42.8571428571429, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=37.5375375375375, Blast_Score=252, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI32566163, Length=339, Percent_Identity=39.5280235988201, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=39.5280235988201, Blast_Score=261, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17534677, Length=339, Percent_Identity=38.6430678466077, Blast_Score=257, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17534679, Length=339, Percent_Identity=38.0530973451327, Blast_Score=255, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=43.75, Blast_Score=296, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=43.75, Blast_Score=293, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6322468, Length=336, Percent_Identity=43.452380952381, Blast_Score=291, Evalue=8e-80,
Organism=Drosophila melanogaster, GI19922412, Length=331, Percent_Identity=43.8066465256798, Blast_Score=281, Evalue=6e-76,
Organism=Drosophila melanogaster, GI85725000, Length=335, Percent_Identity=41.1940298507463, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI22023983, Length=335, Percent_Identity=41.1940298507463, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI17933600, Length=335, Percent_Identity=40.8955223880597, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI18110149, Length=335, Percent_Identity=40.8955223880597, Blast_Score=258, Evalue=3e-69,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37889; Mature: 37889

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGINGFGRIGRLVLRALWDRENIEISHINDPFGDAKGAAHLLEYDSVHGRWNKAISND
CEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHCCC
QNNLSIEGQPISFSQESDYTKVPWNEKGIELILECSGKFKTPQTLNPYFDTLGMKRVVVA
CCCEEEECCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCEEEEE
CPVKGSIQGEDTLNIVYGINHDLYEPNKHRLVTAASCTTNCLAPVVKVVNQAFGIKHGSI
CCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCE
TTLHDLTNTQVIVDSFKSDLRRARSGSQSLIPTTTGSAKAIGMIFPELQGKLNGHAVRVP
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEECHHHCCCCCCCEEEEE
LLNGSLTDAVFELEKEVTQEEVNHVFKEASEGELKGILGYEEKPLVSIDYVNDSRSSIID
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCHHHCC
APSTMVINKSQLKVYIWYDNEWGYSCRMADLVCHVINLEKD
CCCEEEEECCCEEEEEEECCCCCCEEEHHHHHHHHHCCCCC
>Mature Secondary Structure
MRIGINGFGRIGRLVLRALWDRENIEISHINDPFGDAKGAAHLLEYDSVHGRWNKAISND
CEECCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHCCC
QNNLSIEGQPISFSQESDYTKVPWNEKGIELILECSGKFKTPQTLNPYFDTLGMKRVVVA
CCCEEEECCCCCCCCCCCCEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHCCCCEEEEE
CPVKGSIQGEDTLNIVYGINHDLYEPNKHRLVTAASCTTNCLAPVVKVVNQAFGIKHGSI
CCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCE
TTLHDLTNTQVIVDSFKSDLRRARSGSQSLIPTTTGSAKAIGMIFPELQGKLNGHAVRVP
EEEECCCCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEEEECHHHCCCCCCCEEEEE
LLNGSLTDAVFELEKEVTQEEVNHVFKEASEGELKGILGYEEKPLVSIDYVNDSRSSIID
EECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCHHHCC
APSTMVINKSQLKVYIWYDNEWGYSCRMADLVCHVINLEKD
CCCEEEEECCCEEEEEEECCCCCCEEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]