BacMap

Definition	Prochlorococcus marinus str. NATL1A, complete genome.
Accession	NC_008819
Length	1,864,731

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The map label for this gene is ftsH2 [H]

Identifier: 124025672

GI number: 124025672

Start: 884813

End: 886735

Strand: Reverse

Name: ftsH2 [H]

Synonym: NATL1_09651

Alternate gene names: 124025672

Gene position: 886735-884813 (Counterclockwise)

Preceding gene: 124025673

Following gene: 124025670

Centisome position: 47.55

GC content: 38.74

Gene sequence:

>1923_bases
ATGGATAAGAAATGGAAAGTAATAGCACTTTGGGTGCTTCCCATAACAATAGTAATTCTAATTACGTGGCAAATTCTTGG
CTCTTCAACAAATACTCAAGTTAATCAAACGAATACATCTAATCCATCAAGAAATGCTCCGGTTGCAAAGATAAGTTATG
GAAGATTTCTTGATTATGTAAAAGCTGGAAGAGTAACTTCTGTTGACATTTACGATGGTGGTAGAAATGCAATTGTCGAG
TCAGTTGATCCCGAAATTGATAACAGAATTCAACGTTTAAGAGTAGATCTACCAGGATTGGCTCCTGAATTAGTTTCCTC
ACTAAAAGATGAGGGTATCAGTTTTGACATTCATCCACCTAAAACGGCACCAGCGGGAGTAGGAATTCTTGGCAACCTTC
TCTTTCCAATTATTCTAATAGGAGGTCTGATTTTACTTTCAAGAAGATCAAACTCAATGCCAGGTGGTCCAGGGCAAGCA
ATGCAATTTGGTAAAACAAAAGCAAGATTTGCAATGGAAGCTGAGACTGGTGTCAAATTCGATGATGTAGCAGGAGTAAA
TGAAGCGAAACAAGATTTAGAAGAGGTAGTCACATTTTTAAAACAACCTGAAAGATTTACATCTGTAGGTGCTCAAATAC
CAAGAGGTGTTTTACTAGTTGGTCCTCCAGGAACAGGTAAAACCCTATTAGCCAAGGCTATTGCAGGAGAAGCTGGAGTT
CCCTTCTTCTCTCTTTCAGGTTCAGAATTTGTAGAAATGTTTGTGGGTGTAGGTGCAAGTCGTGTCAGAGATTTATTTAA
AAGAGCAAAAGAAAACAGTCCTTGCTTGATTTTCATTGATGAAATTGATGCAGTTGGAAGACAGAGGGGTGCTGGAATTG
GAGGAGGTAATGACGAAAGAGAGCAAACACTCAATCAACTTCTGACTGAGATGGATGGATTTGAAGGTAATAGTGGAATC
ATCATTATTGCAGCAACAAATAGACCTGACGTTCTTGACTCAGCATTAATGAGGCCAGGTAGATTCGATAGACAAGTAAC
CGTTGACGCTCCCGACATATCAGGGAGATTGTCAATTCTCAAAGTTCACTCAAGAAATAAAAAATTAGAAAAGGATTTAA
CTTTAGAAAGTATTGCTAGAAGAACTCCTGGTTTTACAGGTGCTGATTTAGCCAATTTGCTAAATGAAGCAGCTATTCTT
ACAGCCAGAAGAAGAAAGGATCAAATAGGTCTTTCTGAAATAGATGATGCTGTTGATCGCATCATTGCAGGAATGGAAGG
GACACCCCTAGTAGATGGAAGAAGCAAGAGACTCATCGCCTACCACGAGGTTGGTCATGCTTTGATAGGGTCATTAGTAA
AAGATCATGATCCTGTTCAAAAAGTAACTGTTATCCCAAGAGGACAAGCACAAGGTTTGACATGGTTCTCTCCAGATGAT
GATCAGTCTTTGATTAGTAGGGCACAATTAAAAGCAAGAATTATGGGAGCTCTTGGTGGGAGAGCTGCAGAGGATATTAT
TTTCGGAAGAGAAGAAGTAACAACTGGCGCTGGAGGTGATGTACAAATGGTCGCATCAATGGCAAGGCAAATGGTTACGA
GGTTTGGCATGAGCAGCCTCGGTCCAGTTTCATTAGAAGGTGATAGCCAAGAAGTATTTGTAGGAAGAAGCTTAATGAAC
ACATCTGATATATCAGATGGAATTTCAAAGCAAATTGATGAACAAGTCAGATCAATAGTTAAAAAGTGCTACAACGAAAC
ACTTGAATTGGTTGAAAAGAATAGATCAGCTATGGATAAATTGGTTGAAATTTTAATCGAAAAGGAAACTATGGATGGAG
ATGAATTTTGCAAAATATTATCTCAATACACGACTATTCCTGAGAAAGATAGATTTATACCTGTTCTACCAGATGCAAAA
TAG

Upstream 100 bases:

>100_bases
TTTCGAAATATCATTTTTTAAATCTTTCTGAGAAACTGATGAAACCATCCAACAGAAAGGGGCATTACACTATTAGAATC
GTGCGAAAATCTAAAGAATT

Downstream 100 bases:

>100_bases
CAGTTCAATTTCATACTGAATTTATTGGCCTTTTATTAAAGACGTTATCAATAATTCCATATTCGATCGCTTCAGATGGA
GACATGTAGAAGTCTCTGTC

Product: FtsH ATP-dependent protease-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MDKKWKVIALWVLPITIVILITWQILGSSTNTQVNQTNTSNPSRNAPVAKISYGRFLDYVKAGRVTSVDIYDGGRNAIVE
SVDPEIDNRIQRLRVDLPGLAPELVSSLKDEGISFDIHPPKTAPAGVGILGNLLFPIILIGGLILLSRRSNSMPGGPGQA
MQFGKTKARFAMEAETGVKFDDVAGVNEAKQDLEEVVTFLKQPERFTSVGAQIPRGVLLVGPPGTGKTLLAKAIAGEAGV
PFFSLSGSEFVEMFVGVGASRVRDLFKRAKENSPCLIFIDEIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGFEGNSGI
IIIAATNRPDVLDSALMRPGRFDRQVTVDAPDISGRLSILKVHSRNKKLEKDLTLESIARRTPGFTGADLANLLNEAAIL
TARRRKDQIGLSEIDDAVDRIIAGMEGTPLVDGRSKRLIAYHEVGHALIGSLVKDHDPVQKVTVIPRGQAQGLTWFSPDD
DQSLISRAQLKARIMGALGGRAAEDIIFGREEVTTGAGGDVQMVASMARQMVTRFGMSSLGPVSLEGDSQEVFVGRSLMN
TSDISDGISKQIDEQVRSIVKKCYNETLELVEKNRSAMDKLVEILIEKETMDGDEFCKILSQYTTIPEKDRFIPVLPDAK

Sequences:

>Translated_640_residues
MDKKWKVIALWVLPITIVILITWQILGSSTNTQVNQTNTSNPSRNAPVAKISYGRFLDYVKAGRVTSVDIYDGGRNAIVE
SVDPEIDNRIQRLRVDLPGLAPELVSSLKDEGISFDIHPPKTAPAGVGILGNLLFPIILIGGLILLSRRSNSMPGGPGQA
MQFGKTKARFAMEAETGVKFDDVAGVNEAKQDLEEVVTFLKQPERFTSVGAQIPRGVLLVGPPGTGKTLLAKAIAGEAGV
PFFSLSGSEFVEMFVGVGASRVRDLFKRAKENSPCLIFIDEIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGFEGNSGI
IIIAATNRPDVLDSALMRPGRFDRQVTVDAPDISGRLSILKVHSRNKKLEKDLTLESIARRTPGFTGADLANLLNEAAIL
TARRRKDQIGLSEIDDAVDRIIAGMEGTPLVDGRSKRLIAYHEVGHALIGSLVKDHDPVQKVTVIPRGQAQGLTWFSPDD
DQSLISRAQLKARIMGALGGRAAEDIIFGREEVTTGAGGDVQMVASMARQMVTRFGMSSLGPVSLEGDSQEVFVGRSLMN
TSDISDGISKQIDEQVRSIVKKCYNETLELVEKNRSAMDKLVEILIEKETMDGDEFCKILSQYTTIPEKDRFIPVLPDAK
>Mature_640_residues
MDKKWKVIALWVLPITIVILITWQILGSSTNTQVNQTNTSNPSRNAPVAKISYGRFLDYVKAGRVTSVDIYDGGRNAIVE
SVDPEIDNRIQRLRVDLPGLAPELVSSLKDEGISFDIHPPKTAPAGVGILGNLLFPIILIGGLILLSRRSNSMPGGPGQA
MQFGKTKARFAMEAETGVKFDDVAGVNEAKQDLEEVVTFLKQPERFTSVGAQIPRGVLLVGPPGTGKTLLAKAIAGEAGV
PFFSLSGSEFVEMFVGVGASRVRDLFKRAKENSPCLIFIDEIDAVGRQRGAGIGGGNDEREQTLNQLLTEMDGFEGNSGI
IIIAATNRPDVLDSALMRPGRFDRQVTVDAPDISGRLSILKVHSRNKKLEKDLTLESIARRTPGFTGADLANLLNEAAIL
TARRRKDQIGLSEIDDAVDRIIAGMEGTPLVDGRSKRLIAYHEVGHALIGSLVKDHDPVQKVTVIPRGQAQGLTWFSPDD
DQSLISRAQLKARIMGALGGRAAEDIIFGREEVTTGAGGDVQMVASMARQMVTRFGMSSLGPVSLEGDSQEVFVGRSLMN
TSDISDGISKQIDEQVRSIVKKCYNETLELVEKNRSAMDKLVEILIEKETMDGDEFCKILSQYTTIPEKDRFIPVLPDAK

Specific function: Plays a role in the selective replacement of photosystem II (PSII) protein D1 in the PSII repair cycle following visible- light and UV-B induced damage. If damaged D1 is not removed then new D1 cannot be inserted to restore the PSII reaction center. Seems

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein; Stromal side. Note=A fraction is found associated with PSII. Localization to the cell inner membrane has been specifically tested and not seen [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=498, Percent_Identity=44.9799196787149, Blast_Score=425, Evalue=1e-119,
Organism=Homo sapiens, GI21327685, Length=446, Percent_Identity=45.2914798206278, Blast_Score=388, Evalue=1e-108,
Organism=Homo sapiens, GI7657689, Length=446, Percent_Identity=45.2914798206278, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI4507173, Length=516, Percent_Identity=41.0852713178295, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI4506209, Length=262, Percent_Identity=42.7480916030534, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI24497435, Length=244, Percent_Identity=42.2131147540984, Blast_Score=213, Evalue=6e-55,
Organism=Homo sapiens, GI6005942, Length=248, Percent_Identity=42.741935483871, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI21361144, Length=265, Percent_Identity=39.2452830188679, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI195539395, Length=246, Percent_Identity=39.4308943089431, Blast_Score=194, Evalue=3e-49,
Organism=Homo sapiens, GI45643125, Length=234, Percent_Identity=42.3076923076923, Blast_Score=189, Evalue=9e-48,
Organism=Homo sapiens, GI45643123, Length=234, Percent_Identity=42.3076923076923, Blast_Score=189, Evalue=9e-48,
Organism=Homo sapiens, GI24430151, Length=252, Percent_Identity=36.5079365079365, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI157671927, Length=224, Percent_Identity=41.9642857142857, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI40806173, Length=194, Percent_Identity=51.0309278350515, Blast_Score=182, Evalue=8e-46,
Organism=Homo sapiens, GI89064750, Length=246, Percent_Identity=38.2113821138211, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI24430155, Length=246, Percent_Identity=38.2113821138211, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI5729991, Length=246, Percent_Identity=38.2113821138211, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI4505725, Length=221, Percent_Identity=42.0814479638009, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI229577436, Length=244, Percent_Identity=39.344262295082, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI24497618, Length=280, Percent_Identity=37.5, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI194018488, Length=254, Percent_Identity=40.5511811023622, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI153792536, Length=249, Percent_Identity=39.3574297188755, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI14149767, Length=250, Percent_Identity=37.6, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI62177112, Length=250, Percent_Identity=37.6, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI5901990, Length=247, Percent_Identity=38.4615384615385, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI17865802, Length=235, Percent_Identity=38.2978723404255, Blast_Score=144, Evalue=3e-34,
Organism=Homo sapiens, GI11875211, Length=230, Percent_Identity=41.304347826087, Blast_Score=143, Evalue=6e-34,
Organism=Homo sapiens, GI40806170, Length=230, Percent_Identity=41.304347826087, Blast_Score=143, Evalue=6e-34,
Organism=Homo sapiens, GI226371754, Length=236, Percent_Identity=34.3220338983051, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI31742536, Length=226, Percent_Identity=36.283185840708, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI112789543, Length=226, Percent_Identity=36.283185840708, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI7019569, Length=234, Percent_Identity=35.042735042735, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI31377644, Length=232, Percent_Identity=35.7758620689655, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI156564401, Length=220, Percent_Identity=37.7272727272727, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI310125280, Length=220, Percent_Identity=37.2727272727273, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI310125282, Length=220, Percent_Identity=37.2727272727273, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI64084766, Length=225, Percent_Identity=31.5555555555556, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI116292174, Length=224, Percent_Identity=30.3571428571429, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1789568, Length=624, Percent_Identity=46.474358974359, Blast_Score=534, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71994521, Length=462, Percent_Identity=46.5367965367965, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17554264, Length=439, Percent_Identity=43.7357630979499, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI115534323, Length=455, Percent_Identity=43.0769230769231, Blast_Score=345, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI25144278, Length=244, Percent_Identity=42.6229508196721, Blast_Score=216, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI25144281, Length=244, Percent_Identity=42.6229508196721, Blast_Score=215, Evalue=5e-56,
Organism=Caenorhabditis elegans, GI17554786, Length=244, Percent_Identity=42.2131147540984, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17563248, Length=254, Percent_Identity=42.1259842519685, Blast_Score=214, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17531535, Length=248, Percent_Identity=43.9516129032258, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17532375, Length=243, Percent_Identity=43.6213991769547, Blast_Score=206, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17508701, Length=241, Percent_Identity=41.49377593361, Blast_Score=202, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI71987364, Length=240, Percent_Identity=38.75, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI71987372, Length=240, Percent_Identity=38.75, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17537217, Length=258, Percent_Identity=40.6976744186046, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17505546, Length=249, Percent_Identity=39.3574297188755, Blast_Score=189, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI17563250, Length=252, Percent_Identity=36.9047619047619, Blast_Score=185, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17508053, Length=258, Percent_Identity=38.3720930232558, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI25153574, Length=243, Percent_Identity=39.5061728395062, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI193209502, Length=244, Percent_Identity=39.344262295082, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17554784, Length=246, Percent_Identity=37.3983739837398, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI133931034, Length=249, Percent_Identity=38.5542168674699, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193206114, Length=249, Percent_Identity=38.5542168674699, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI193206116, Length=249, Percent_Identity=38.5542168674699, Blast_Score=163, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17562804, Length=230, Percent_Identity=37.3913043478261, Blast_Score=148, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI133901658, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI133901662, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI86561515, Length=233, Percent_Identity=36.0515021459227, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI25146157, Length=234, Percent_Identity=37.1794871794872, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17570397, Length=180, Percent_Identity=40.5555555555556, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI32566590, Length=180, Percent_Identity=40.5555555555556, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17508421, Length=240, Percent_Identity=36.6666666666667, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563584, Length=240, Percent_Identity=36.6666666666667, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17541224, Length=234, Percent_Identity=34.1880341880342, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17541226, Length=234, Percent_Identity=34.1880341880342, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17560432, Length=254, Percent_Identity=34.6456692913386, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=29.2929292929293, Blast_Score=73, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320854, Length=512, Percent_Identity=46.6796875, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6323736, Length=515, Percent_Identity=44.8543689320388, Blast_Score=432, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6325281, Length=450, Percent_Identity=44.2222222222222, Blast_Score=378, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6322704, Length=258, Percent_Identity=41.4728682170543, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321390, Length=252, Percent_Identity=40.0793650793651, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320077, Length=237, Percent_Identity=44.3037974683544, Blast_Score=208, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6324833, Length=254, Percent_Identity=42.5196850393701, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320197, Length=244, Percent_Identity=37.7049180327869, Blast_Score=191, Evalue=3e-49,
Organism=Saccharomyces cerevisiae, GI6324691, Length=264, Percent_Identity=35.9848484848485, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6322651, Length=263, Percent_Identity=39.5437262357414, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6324000, Length=234, Percent_Identity=42.7350427350427, Blast_Score=177, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6323429, Length=224, Percent_Identity=40.1785714285714, Blast_Score=175, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6320602, Length=242, Percent_Identity=38.8429752066116, Blast_Score=174, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322994, Length=208, Percent_Identity=46.6346153846154, Blast_Score=173, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6321709, Length=249, Percent_Identity=38.1526104417671, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6321465, Length=238, Percent_Identity=38.2352941176471, Blast_Score=141, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6325431, Length=232, Percent_Identity=37.5, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6325183, Length=252, Percent_Identity=34.9206349206349, Blast_Score=137, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6319554, Length=213, Percent_Identity=38.0281690140845, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320887, Length=249, Percent_Identity=32.1285140562249, Blast_Score=121, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6320583, Length=193, Percent_Identity=32.1243523316062, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24665814, Length=505, Percent_Identity=46.5346534653465, Blast_Score=427, Evalue=1e-120,
Organism=Drosophila melanogaster, GI28574878, Length=505, Percent_Identity=46.5346534653465, Blast_Score=427, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24639391, Length=453, Percent_Identity=44.5916114790287, Blast_Score=392, Evalue=1e-109,
Organism=Drosophila melanogaster, GI24658770, Length=453, Percent_Identity=43.046357615894, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI17137738, Length=262, Percent_Identity=42.3664122137405, Blast_Score=212, Evalue=6e-55,
Organism=Drosophila melanogaster, GI24651451, Length=244, Percent_Identity=42.2131147540984, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI17137560, Length=248, Percent_Identity=43.1451612903226, Blast_Score=208, Evalue=8e-54,
Organism=Drosophila melanogaster, GI161076488, Length=248, Percent_Identity=43.1451612903226, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI19920408, Length=244, Percent_Identity=41.3934426229508, Blast_Score=208, Evalue=9e-54,
Organism=Drosophila melanogaster, GI161076486, Length=248, Percent_Identity=43.1451612903226, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI45554047, Length=166, Percent_Identity=58.433734939759, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24660075, Length=245, Percent_Identity=44.4897959183673, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI281365776, Length=245, Percent_Identity=44.4897959183673, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI45552965, Length=245, Percent_Identity=44.4897959183673, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17738151, Length=241, Percent_Identity=40.6639004149378, Blast_Score=199, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=37.9591836734694, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24656820, Length=264, Percent_Identity=39.3939393939394, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24656825, Length=264, Percent_Identity=39.3939393939394, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24649446, Length=252, Percent_Identity=36.5079365079365, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24663015, Length=246, Percent_Identity=37.3983739837398, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI18860063, Length=230, Percent_Identity=39.5652173913043, Blast_Score=180, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281361487, Length=230, Percent_Identity=39.5652173913043, Blast_Score=179, Evalue=7e-45,
Organism=Drosophila melanogaster, GI24652279, Length=193, Percent_Identity=44.0414507772021, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI19921202, Length=226, Percent_Identity=38.4955752212389, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355121, Length=237, Percent_Identity=35.8649789029536, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281363136, Length=238, Percent_Identity=37.8151260504202, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI78707192, Length=238, Percent_Identity=37.8151260504202, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24644145, Length=243, Percent_Identity=35.3909465020576, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI18859657, Length=234, Percent_Identity=38.034188034188, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI281360144, Length=239, Percent_Identity=37.2384937238494, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360140, Length=239, Percent_Identity=37.2384937238494, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360136, Length=239, Percent_Identity=37.2384937238494, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24644411, Length=239, Percent_Identity=37.2384937238494, Blast_Score=143, Evalue=4e-34,
Organism=Drosophila melanogaster, GI281360146, Length=239, Percent_Identity=37.2384937238494, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281360138, Length=239, Percent_Identity=37.2384937238494, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI281360142, Length=239, Percent_Identity=37.2384937238494, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI21357333, Length=239, Percent_Identity=37.2384937238494, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24581396, Length=234, Percent_Identity=38.8888888888889, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI20129529, Length=233, Percent_Identity=34.7639484978541, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17864540, Length=209, Percent_Identity=36.8421052631579, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI20129423, Length=243, Percent_Identity=33.7448559670782, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28571849, Length=238, Percent_Identity=36.5546218487395, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28571847, Length=238, Percent_Identity=36.5546218487395, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28573010, Length=217, Percent_Identity=36.405529953917, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24639486, Length=187, Percent_Identity=34.2245989304813, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 69458; Mature: 69458

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00142 ZINC_PROTEASE ; PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKKWKVIALWVLPITIVILITWQILGSSTNTQVNQTNTSNPSRNAPVAKISYGRFLDYV
CCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEHHHHHHHHH
KAGRVTSVDIYDGGRNAIVESVDPEIDNRIQRLRVDLPGLAPELVSSLKDEGISFDIHPP
HCCCEEEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCC
KTAPAGVGILGNLLFPIILIGGLILLSRRSNSMPGGPGQAMQFGKTKARFAMEAETGVKF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHEEEECCCCCCH
DDVAGVNEAKQDLEEVVTFLKQPERFTSVGAQIPRGVLLVGPPGTGKTLLAKAIAGEAGV
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCC
PFFSLSGSEFVEMFVGVGASRVRDLFKRAKENSPCLIFIDEIDAVGRQRGAGIGGGNDER
CEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHCCCCCCCCCHHH
EQTLNQLLTEMDGFEGNSGIIIIAATNRPDVLDSALMRPGRFDRQVTVDAPDISGRLSIL
HHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
KVHSRNKKLEKDLTLESIARRTPGFTGADLANLLNEAAILTARRRKDQIGLSEIDDAVDR
EEECCCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IIAGMEGTPLVDGRSKRLIAYHEVGHALIGSLVKDHDPVQKVTVIPRGQAQGLTWFSPDD
HHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
DQSLISRAQLKARIMGALGGRAAEDIIFGREEVTTGAGGDVQMVASMARQMVTRFGMSSL
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
GPVSLEGDSQEVFVGRSLMNTSDISDGISKQIDEQVRSIVKKCYNETLELVEKNRSAMDK
CCEEECCCCCEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEILIEKETMDGDEFCKILSQYTTIPEKDRFIPVLPDAK
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MDKKWKVIALWVLPITIVILITWQILGSSTNTQVNQTNTSNPSRNAPVAKISYGRFLDYV
CCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEEHHHHHHHHH
KAGRVTSVDIYDGGRNAIVESVDPEIDNRIQRLRVDLPGLAPELVSSLKDEGISFDIHPP
HCCCEEEEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEECCCC
KTAPAGVGILGNLLFPIILIGGLILLSRRSNSMPGGPGQAMQFGKTKARFAMEAETGVKF
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHEEEECCCCCCH
DDVAGVNEAKQDLEEVVTFLKQPERFTSVGAQIPRGVLLVGPPGTGKTLLAKAIAGEAGV
HHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCCC
PFFSLSGSEFVEMFVGVGASRVRDLFKRAKENSPCLIFIDEIDAVGRQRGAGIGGGNDER
CEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHCCCCCCCCCHHH
EQTLNQLLTEMDGFEGNSGIIIIAATNRPDVLDSALMRPGRFDRQVTVDAPDISGRLSIL
HHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCEEEECCCCCCCCEEEE
KVHSRNKKLEKDLTLESIARRTPGFTGADLANLLNEAAILTARRRKDQIGLSEIDDAVDR
EEECCCCHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
IIAGMEGTPLVDGRSKRLIAYHEVGHALIGSLVKDHDPVQKVTVIPRGQAQGLTWFSPDD
HHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCC
DQSLISRAQLKARIMGALGGRAAEDIIFGREEVTTGAGGDVQMVASMARQMVTRFGMSSL
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
GPVSLEGDSQEVFVGRSLMNTSDISDGISKQIDEQVRSIVKKCYNETLELVEKNRSAMDK
CCEEECCCCCEEEECHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVEILIEKETMDGDEFCKILSQYTTIPEKDRFIPVLPDAK
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 12069591 [H]