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The map label for this gene is rlmH

Identifier: 124025652

GI number: 124025652

Start: 872448

End: 872885

Strand: Reverse

Name: rlmH

Synonym: NATL1_09451

Alternate gene names: 124025652

Gene position: 872885-872448 (Counterclockwise)

Preceding gene: 124025653

Following gene: 124025651

Centisome position: 46.81

GC content: 33.33

Gene sequence:

>438_bases
ATGCTTAATATTTCACACTATAAAATCATTGCTATAGGAAAAATAAGAAAAAAGTGGATTCAAGAGGGTATAGAAATGTA
CCTAAAAAGATTACCTGGTTTAGAAGTTAAAGAAATTAAAGACAGCACACAATTAAAAGAAGAACATACGATCAAAGAAA
TTATCAGCAAAAATGAATTTCTGGTAACTCTTAACGAAAATGGTCAATCATTTACATCAAAACAACTAGCAACAAAACTT
CTAAATTCTCACAATCAAAATATTACTTTTGTTATTGGAGGTGCTTCAGGTCTTACCTCTTCCCTTAACAATTTAGCCTC
TTGGCAATTAAGTCTTTCACCTCTAACTTTTCCGCATGAAATAGCTCGCCTATTACTAATAGAACAGCTCTACCGCGCAA
AAACAATCACCCAAGGAGGCCCTTACCACAAGGAATAG

Upstream 100 bases:

>100_bases
ATAAAAATTCTAATGATCTTTCAGCTGAAGATGCCCTAAACCTATACACACAATTTCAACAATTTCTACTCGAAGATGAT
ATCGATTAGAAAAAAACTTT

Downstream 100 bases:

>100_bases
GCAGGCCCGAAGGAAGAATAATAGTTCAGGTGTACTATAATGCATTGTATTGATCTGGTCCTATGGGTTCAAATCGCTCT
CGCTCTTCATCAACAGAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MLNISHYKIIAIGKIRKKWIQEGIEMYLKRLPGLEVKEIKDSTQLKEEHTIKEIISKNEFLVTLNENGQSFTSKQLATKL
LNSHNQNITFVIGGASGLTSSLNNLASWQLSLSPLTFPHEIARLLLIEQLYRAKTITQGGPYHKE

Sequences:

>Translated_145_residues
MLNISHYKIIAIGKIRKKWIQEGIEMYLKRLPGLEVKEIKDSTQLKEEHTIKEIISKNEFLVTLNENGQSFTSKQLATKL
LNSHNQNITFVIGGASGLTSSLNNLASWQLSLSPLTFPHEIARLLLIEQLYRAKTITQGGPYHKE
>Mature_145_residues
MLNISHYKIIAIGKIRKKWIQEGIEMYLKRLPGLEVKEIKDSTQLKEEHTIKEIISKNEFLVTLNENGQSFTSKQLATKL
LNSHNQNITFVIGGASGLTSSLNNLASWQLSLSPLTFPHEIARLLLIEQLYRAKTITQGGPYHKE

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=153, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_PROM1 (A2C1Z3)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014768.1
- ProteinModelPortal:   A2C1Z3
- SMR:   A2C1Z3
- STRING:   A2C1Z3
- GeneID:   4780844
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_09451
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   NISHYKI
- ProtClustDB:   CLSK919387
- BioCyc:   PMAR167555:NATL1_09451-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 16471; Mature: 16471

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNISHYKIIAIGKIRKKWIQEGIEMYLKRLPGLEVKEIKDSTQLKEEHTIKEIISKNEF
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
LVTLNENGQSFTSKQLATKLLNSHNQNITFVIGGASGLTSSLNNLASWQLSLSPLTFPHE
EEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHEEECCCCCCHHH
IARLLLIEQLYRAKTITQGGPYHKE
HHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLNISHYKIIAIGKIRKKWIQEGIEMYLKRLPGLEVKEIKDSTQLKEEHTIKEIISKNEF
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCE
LVTLNENGQSFTSKQLATKLLNSHNQNITFVIGGASGLTSSLNNLASWQLSLSPLTFPHE
EEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHEEECCCCCCHHH
IARLLLIEQLYRAKTITQGGPYHKE
HHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA