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The map label for this gene is 124025646

Identifier: 124025646

GI number: 124025646

Start: 866803

End: 867711

Strand: Reverse

Name: 124025646

Synonym: NATL1_09391

Alternate gene names: NA

Gene position: 867711-866803 (Counterclockwise)

Preceding gene: 124025649

Following gene: 124025645

Centisome position: 46.53

GC content: 31.13

Gene sequence:

>909_bases
TTGAGAGAAAACCTACTTACCAATAAATTAAATATAGAAAAAAATTTTAAAGGGATCAGATTTTTAATAGGAAGCGGTTT
TGCATTTAGCCTTATGACTGTTTGTGTGAAGGGGATTGGGGGAAGGATCCCTATTTCAGAACTTGTATTTGCTAGAGCTA
CAATAAGTATAATAATAACAAGATTTTACTTATATAAAAATAACATTAACCCTTGGGGATATCAGAAAAGATTATTAATT
ATAAGGGGTTTACTAGGAACAGTTGCACTATTTTGTATTTTCAAAGCTCTTACAATATTACCTATTGCAACAGCAACAGT
AATACAATATATTTATCCAACTTTTACAGTGATATGTGCTTACATAATTTTAAAGGAATTTATATTCAGAAGAATAGTAT
ATTCAATTATTATTGGCTGGATAGGAATTGTTTTAGTTAGTCAGCCGGAATTCACCAGCAACAGTAATATTCAAGAGACA
ATATTAGCAATAATCATTGCAATATTTGGTGCACTGATGACATCATTGGCATATATATGTGTAAGGAAGCTTTCTTCCAA
AGAACACCCTCTTGTAATTATTTACTACTTTCCTTTGGTCTCTATCCCCTTATCTATTCCTTTTATTATTAATGATTTTG
TATTACCTTCGGGTACAGATTGGTTCTTGATAATAGGTATTGGTATTTTCACACAGATTGGACAACTCTGCATAACAGAG
GGGTTAAGACTACTACCAGCTGGCCAAGCAACTTCACTAAATTATTCACAAGTTATATTTGCATGTATATGGGGAGTATT
GATATTTCAAGAAACAATAACAAGTTCAATATACATAGGTGGATTTTGCGTTCTTATTTCTACTATTATTAGTATGAGTG
CATCCAAGAGAACACAATCAAAAATATGA

Upstream 100 bases:

>100_bases
ACGCGCTCTTTTACAGACTCAATGTCTTAGGATGTAGTCGAGCAGAAGCCATATGATAATTTTAATTGATATTTAAATAT
TTAGTTAAGAGATTTAGGAA

Downstream 100 bases:

>100_bases
ATTGTAAATCTTTAATTTTTTCAATAGTATTTATTTGCACTGGATCAACATCGATTCTTGCAGATGAATATCAGCGAGGC
TACTCTTCTAGTAAAACTTG

Product: integral membrane protein, DUF6

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MRENLLTNKLNIEKNFKGIRFLIGSGFAFSLMTVCVKGIGGRIPISELVFARATISIIITRFYLYKNNINPWGYQKRLLI
IRGLLGTVALFCIFKALTILPIATATVIQYIYPTFTVICAYIILKEFIFRRIVYSIIIGWIGIVLVSQPEFTSNSNIQET
ILAIIIAIFGALMTSLAYICVRKLSSKEHPLVIIYYFPLVSIPLSIPFIINDFVLPSGTDWFLIIGIGIFTQIGQLCITE
GLRLLPAGQATSLNYSQVIFACIWGVLIFQETITSSIYIGGFCVLISTIISMSASKRTQSKI

Sequences:

>Translated_302_residues
MRENLLTNKLNIEKNFKGIRFLIGSGFAFSLMTVCVKGIGGRIPISELVFARATISIIITRFYLYKNNINPWGYQKRLLI
IRGLLGTVALFCIFKALTILPIATATVIQYIYPTFTVICAYIILKEFIFRRIVYSIIIGWIGIVLVSQPEFTSNSNIQET
ILAIIIAIFGALMTSLAYICVRKLSSKEHPLVIIYYFPLVSIPLSIPFIINDFVLPSGTDWFLIIGIGIFTQIGQLCITE
GLRLLPAGQATSLNYSQVIFACIWGVLIFQETITSSIYIGGFCVLISTIISMSASKRTQSKI
>Mature_302_residues
MRENLLTNKLNIEKNFKGIRFLIGSGFAFSLMTVCVKGIGGRIPISELVFARATISIIITRFYLYKNNINPWGYQKRLLI
IRGLLGTVALFCIFKALTILPIATATVIQYIYPTFTVICAYIILKEFIFRRIVYSIIIGWIGIVLVSQPEFTSNSNIQET
ILAIIIAIFGALMTSLAYICVRKLSSKEHPLVIIYYFPLVSIPLSIPFIINDFVLPSGTDWFLIIGIGIFTQIGQLCITE
GLRLLPAGQATSLNYSQVIFACIWGVLIFQETITSSIYIGGFCVLISTIISMSASKRTQSKI

Specific function: Unknown

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Homo sapiens, GI197927233, Length=284, Percent_Identity=27.112676056338, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI23397492, Length=284, Percent_Identity=27.4647887323944, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324991, Length=330, Percent_Identity=27.5757575757576, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323909, Length=252, Percent_Identity=26.1904761904762, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24645940, Length=298, Percent_Identity=27.1812080536913, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 33724; Mature: 33724

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRENLLTNKLNIEKNFKGIRFLIGSGFAFSLMTVCVKGIGGRIPISELVFARATISIIIT
CCCCHHHCCCCCHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RFYLYKNNINPWGYQKRLLIIRGLLGTVALFCIFKALTILPIATATVIQYIYPTFTVICA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIILKEFIFRRIVYSIIIGWIGIVLVSQPEFTSNSNIQETILAIIIAIFGALMTSLAYIC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRKLSSKEHPLVIIYYFPLVSIPLSIPFIINDFVLPSGTDWFLIIGIGIFTQIGQLCITE
HHHHCCCCCCEEEEEHHHHHHCCCCCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHC
GLRLLPAGQATSLNYSQVIFACIWGVLIFQETITSSIYIGGFCVLISTIISMSASKRTQS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KI
CC
>Mature Secondary Structure
MRENLLTNKLNIEKNFKGIRFLIGSGFAFSLMTVCVKGIGGRIPISELVFARATISIIIT
CCCCHHHCCCCCHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RFYLYKNNINPWGYQKRLLIIRGLLGTVALFCIFKALTILPIATATVIQYIYPTFTVICA
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIILKEFIFRRIVYSIIIGWIGIVLVSQPEFTSNSNIQETILAIIIAIFGALMTSLAYIC
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRKLSSKEHPLVIIYYFPLVSIPLSIPFIINDFVLPSGTDWFLIIGIGIFTQIGQLCITE
HHHHCCCCCCEEEEEHHHHHHCCCCCCHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHC
GLRLLPAGQATSLNYSQVIFACIWGVLIFQETITSSIYIGGFCVLISTIISMSASKRTQS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
KI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]