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The map label for this gene is aroQ

Identifier: 124025151

GI number: 124025151

Start: 402442

End: 402879

Strand: Direct

Name: aroQ

Synonym: NATL1_04381

Alternate gene names: 124025151

Gene position: 402442-402879 (Clockwise)

Preceding gene: 124025150

Following gene: 124025152

Centisome position: 21.58

GC content: 35.16

Gene sequence:

>438_bases
ATGGATCTTTTACTTATTAATGGTCCAAATTTAAATCTTGTTGGGAAAAGGGAACCATCCATATATGGTTCGCAAACTTT
AGAAGACATTCAAGAAGAGTTATTGACTTTAGCTAATGAGCTTGGTGCAAACCTCAAATTCTTTCAGAGTAATTCAGAGG
GCGAGATGATTGATTGCATTCAAAACAGTGTTGGTTCCATTGACGGAATATTGATTAATGCAGGCGCATATACACATACC
TCTATTGCTCTTAGAGATGCTTTATTAGGAGTTGCTATTCCTTATGTAGAAGTACATTTAAGTAATATCTATTCTAGGGA
AGAATTTCGCCATAAATCATTCCTTTCAGATAAAGCATTGGGTTTGGTTTGTGGCTTTGGAGCAAATAGTTATCAACTTG
CTTTAGAAGGCATAGTTTCCTATTTAAAGCGAGTATGA

Upstream 100 bases:

>100_bases
TAATGAGATTAACAGTAAATGGTGCCACTTTTCTCGAATTTGTTGGTCCTTTGTGGTCGGAATCGATACGATCAAATAAA
TTGTTTAACTTATAGAGAAT

Downstream 100 bases:

>100_bases
GAGGTTTATGGATAATTCAATATCTCAAATTGCAGGGCCATCAAAGATTCGCTGGCTAATAAATAAAACTTCTGAAGATT
GGGTTGATCTTGCAATTTCT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDLLLINGPNLNLVGKREPSIYGSQTLEDIQEELLTLANELGANLKFFQSNSEGEMIDCIQNSVGSIDGILINAGAYTHT
SIALRDALLGVAIPYVEVHLSNIYSREEFRHKSFLSDKALGLVCGFGANSYQLALEGIVSYLKRV

Sequences:

>Translated_145_residues
MDLLLINGPNLNLVGKREPSIYGSQTLEDIQEELLTLANELGANLKFFQSNSEGEMIDCIQNSVGSIDGILINAGAYTHT
SIALRDALLGVAIPYVEVHLSNIYSREEFRHKSFLSDKALGLVCGFGANSYQLALEGIVSYLKRV
>Mature_145_residues
MDLLLINGPNLNLVGKREPSIYGSQTLEDIQEELLTLANELGANLKFFQSNSEGEMIDCIQNSVGSIDGILINAGAYTHT
SIALRDALLGVAIPYVEVHLSNIYSREEFRHKSFLSDKALGLVCGFGANSYQLALEGIVSYLKRV

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_PROM1 (A2C0J2)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014267.1
- ProteinModelPortal:   A2C0J2
- SMR:   A2C0J2
- STRING:   A2C0J2
- GeneID:   4780345
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_04381
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   PMAR167555:NATL1_04381-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15848; Mature: 15848

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 22-22 ACT_SITE 99-99 BINDING 73-73 BINDING 79-79 BINDING 86-86 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLINGPNLNLVGKREPSIYGSQTLEDIQEELLTLANELGANLKFFQSNSEGEMIDCI
CCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
QNSVGSIDGILINAGAYTHTSIALRDALLGVAIPYVEVHLSNIYSREEFRHKSFLSDKAL
HHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLVCGFGANSYQLALEGIVSYLKRV
EEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLLLINGPNLNLVGKREPSIYGSQTLEDIQEELLTLANELGANLKFFQSNSEGEMIDCI
CCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
QNSVGSIDGILINAGAYTHTSIALRDALLGVAIPYVEVHLSNIYSREEFRHKSFLSDKAL
HHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLVCGFGANSYQLALEGIVSYLKRV
EEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA