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The map label for this gene is btuR [C]

Identifier: 124025036

GI number: 124025036

Start: 300142

End: 300738

Strand: Reverse

Name: btuR [C]

Synonym: NATL1_03231

Alternate gene names: 124025036

Gene position: 300738-300142 (Counterclockwise)

Preceding gene: 124025040

Following gene: 124025035

Centisome position: 16.13

GC content: 36.35

Gene sequence:

>597_bases
ATGAATGCACGAGTGAGCATTAATGCTCAACAGAGGGGTTCATCACCGTCAAAAGAGACTTCTCTAAGGCCTACCCCCAT
TAGAAAGCCTTTACAACTAGTTGCAACACAAGGTCAAGTTCAAATCCACACTTCTACTTTTAGAGGTAGTTTTTCCGTTG
TTCTTAGTGAGGCAATTAGATCTGCAGGATTGGGAAGCCAAGTTTTGATAGCTCAATTTTTGAGAGGTGGAGTCAACCAA
GGACCAAATGGAGCTATCAATCTTTGCGGGCGACTTGAGTGGTTAAGACCAGCCATTGAAACGTGCTTGCAAGAAAAAAT
ATTGGAAGAACATTTATCTTTAAAAAGAAAATATTATGAAAAAGCGATCAAAGAACTCTGGGAATTTTGCAAATCTCGTT
TAATCGAAAAAAAAATAGATAAAATCGTTCTCGATGAAATAGGAATAGCTATTAGCCTTGGTTTTATTGAAGAAAATGAT
TTAATTTTTATGATAAATAATCGACCATCATCCACAGATATTATTCTTACAGGACCATCAATCCCTCCTAAAGTAATTGA
AATGGCTGATCAAATCACTGAATTACGCTGCAATTAA

Upstream 100 bases:

>100_bases
CCAAGTATTTTGACTCCATACACCACAGATAGTGTTGAATTGGTTGATTAGAAATTTTATGCCGCTAGATTAGTTATAAG
ACATTCTGATAAAAATCAAG

Downstream 100 bases:

>100_bases
ATGTTAAAAAACGATCTTTGGATTGCTGAACAGGCTTCACTAGGAATGCTTGAACCTTTTCAAGAAAAGCTAATAAGACA
TCTTGAGCCAGAATCCGAAA

Product: cob(I)alamin adenosyltransferase

Products: triphosphate; adenosylcob(III)yrinic acid a,c-diamide; Adenosyl cobinamide

Alternate protein names: Cob(I)Yrinic Acid A C-Diamide Adenosyltransferase; ATPCorrinoid Adenosyltransferase; ATPCorrinoid Adenosyltransferase BtuR/CobO/CobP; Cob(I)Yrinate A C-Diamide Adenosyltransferase; ATP Corrinoid Adenosyltransferase; ATP Corrinoid Adenosyltransferase BtuR/CobO/CobP; Corrinoid Adenosyltransferase BtuR/CobO/CobP

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MNARVSINAQQRGSSPSKETSLRPTPIRKPLQLVATQGQVQIHTSTFRGSFSVVLSEAIRSAGLGSQVLIAQFLRGGVNQ
GPNGAINLCGRLEWLRPAIETCLQEKILEEHLSLKRKYYEKAIKELWEFCKSRLIEKKIDKIVLDEIGIAISLGFIEEND
LIFMINNRPSSTDIILTGPSIPPKVIEMADQITELRCN

Sequences:

>Translated_198_residues
MNARVSINAQQRGSSPSKETSLRPTPIRKPLQLVATQGQVQIHTSTFRGSFSVVLSEAIRSAGLGSQVLIAQFLRGGVNQ
GPNGAINLCGRLEWLRPAIETCLQEKILEEHLSLKRKYYEKAIKELWEFCKSRLIEKKIDKIVLDEIGIAISLGFIEEND
LIFMINNRPSSTDIILTGPSIPPKVIEMADQITELRCN
>Mature_198_residues
MNARVSINAQQRGSSPSKETSLRPTPIRKPLQLVATQGQVQIHTSTFRGSFSVVLSEAIRSAGLGSQVLIAQFLRGGVNQ
GPNGAINLCGRLEWLRPAIETCLQEKILEEHLSLKRKYYEKAIKELWEFCKSRLIEKKIDKIVLDEIGIAISLGFIEEND
LIFMINNRPSSTDIILTGPSIPPKVIEMADQITELRCN

Specific function: Required For Both De Novo Synthesis Of The Corrin Ring For The Assimilation Of Exogenous Corrinoids. Participates In The Adenosylation Of A Variety Of Incomplete And Complete Corrinoids (By Similarity). [C]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787525, Length=163, Percent_Identity=24.5398773006135, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.17

Molecular weight: Translated: 22083; Mature: 22083

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARVSINAQQRGSSPSKETSLRPTPIRKPLQLVATQGQVQIHTSTFRGSFSVVLSEAIR
CCCEEEECHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECHHCCHHHHHHHHHHH
SAGLGSQVLIAQFLRGGVNQGPNGAINLCGRLEWLRPAIETCLQEKILEEHLSLKRKYYE
HCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAIKELWEFCKSRLIEKKIDKIVLDEIGIAISLGFIEENDLIFMINNRPSSTDIILTGPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEECCCCCCCEEEEECCC
IPPKVIEMADQITELRCN
CCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNARVSINAQQRGSSPSKETSLRPTPIRKPLQLVATQGQVQIHTSTFRGSFSVVLSEAIR
CCCEEEECHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECHHCCHHHHHHHHHHH
SAGLGSQVLIAQFLRGGVNQGPNGAINLCGRLEWLRPAIETCLQEKILEEHLSLKRKYYE
HCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAIKELWEFCKSRLIEKKIDKIVLDEIGIAISLGFIEENDLIFMINNRPSSTDIILTGPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEEEECCCCCCCEEEEECCC
IPPKVIEMADQITELRCN
CCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)yrinic acid a,c-diamide; cobinamide

Specific reaction: (1) ATP + cob(I)yrinic acid a,c-diamide = triphosphate + adenosylcob(III)yrinic acid a,c-diamide; (2) ATP + cobinamide = triphosphate + adenosylcobinamide

General reaction: Adenosyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA