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The map label for this gene is mpg

Identifier: 124025026

GI number: 124025026

Start: 290728

End: 291297

Strand: Reverse

Name: mpg

Synonym: NATL1_03131

Alternate gene names: NA

Gene position: 291297-290728 (Counterclockwise)

Preceding gene: 124025028

Following gene: 124025025

Centisome position: 15.62

GC content: 38.25

Gene sequence:

>570_bases
ATGGTCGCACCTAGCTTAATTGGCTGTTTTTTAATTAAGCGCTTATCAGAAAACAGCTATCTTGCCGGCGCAATTGTTGA
AACTGAGGCTTATTCTCAAGAAGAAGCTTCATGCCATGGCTTCTCAGGGAGAACTCAAAGAAACAAAACCCTTTTTGGTG
AACCAGGTAACTTTTACATATACCTTTCATATGGAATTAATAGTTGTGTGAATATTGTTACTGGGAAGAAAAACTGGGCA
AATGGTGTACTTCTTCGATCGATAGCAATAAAAGGAGAACACGAGAGAATTGCTTCTGGGCCTGGATTATTGGCAAAAAG
ATTTGGATTAAATAAGAATTTTGACAACTTACACTTGTCACCTGCAAATGATTTTTGGTTATCAGAGGGAGAAGATTTAA
CAAGAATGGGAAATATTGTTCAGACCACAAGGATTGGCATTTCGCAAGCCAAAGATATACCTTGGCGTTGGTACCTTAAA
AGTAGTAGAAGTGTTAGCAAAAGGGTTAGAGGTGATCGAATTCCTCCAAAAAATAAGTGTTGGGAACCATCAGCATTTGA
GGGATTATGA

Upstream 100 bases:

>100_bases
AAGATAGAGAAATCTATTATTTAGTAAGTACTATGGATAAAAAAGAAATAGTAAGCAAATCTCACTTCTTACAAGAGAAT
TCTTTTCAAGGCCATCTCAT

Downstream 100 bases:

>100_bases
ATAATTGGAAACATAATCACGTTCTTGATTTATCTACGTTTTCTTTAGAGGATTACAAAACAGTTTTAGAATTAACAACA
AGATTTAAAGATGTCCATAA

Product: methylpurine-DNA glycosylase (MPG)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MVAPSLIGCFLIKRLSENSYLAGAIVETEAYSQEEASCHGFSGRTQRNKTLFGEPGNFYIYLSYGINSCVNIVTGKKNWA
NGVLLRSIAIKGEHERIASGPGLLAKRFGLNKNFDNLHLSPANDFWLSEGEDLTRMGNIVQTTRIGISQAKDIPWRWYLK
SSRSVSKRVRGDRIPPKNKCWEPSAFEGL

Sequences:

>Translated_189_residues
MVAPSLIGCFLIKRLSENSYLAGAIVETEAYSQEEASCHGFSGRTQRNKTLFGEPGNFYIYLSYGINSCVNIVTGKKNWA
NGVLLRSIAIKGEHERIASGPGLLAKRFGLNKNFDNLHLSPANDFWLSEGEDLTRMGNIVQTTRIGISQAKDIPWRWYLK
SSRSVSKRVRGDRIPPKNKCWEPSAFEGL
>Mature_189_residues
MVAPSLIGCFLIKRLSENSYLAGAIVETEAYSQEEASCHGFSGRTQRNKTLFGEPGNFYIYLSYGINSCVNIVTGKKNWA
NGVLLRSIAIKGEHERIASGPGLLAKRFGLNKNFDNLHLSPANDFWLSEGEDLTRMGNIVQTTRIGISQAKDIPWRWYLK
SSRSVSKRVRGDRIPPKNKCWEPSAFEGL

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=151, Percent_Identity=33.7748344370861, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI62632765, Length=151, Percent_Identity=33.7748344370861, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI62632771, Length=151, Percent_Identity=33.7748344370861, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 21114; Mature: 21114

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPSLIGCFLIKRLSENSYLAGAIVETEAYSQEEASCHGFSGRTQRNKTLFGEPGNFYI
CCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEE
YLSYGINSCVNIVTGKKNWANGVLLRSIAIKGEHERIASGPGLLAKRFGLNKNFDNLHLS
EEECCCCHHHEEHCCCCCCCCCEEEEEEEECCCHHHHCCCCCHHHHHHCCCCCCCCEEEC
PANDFWLSEGEDLTRMGNIVQTTRIGISQAKDIPWRWYLKSSRSVSKRVRGDRIPPKNKC
CCCCCCCCCCCCHHHHCCHHHHHHCCCHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCCC
WEPSAFEGL
CCCCCCCCC
>Mature Secondary Structure
MVAPSLIGCFLIKRLSENSYLAGAIVETEAYSQEEASCHGFSGRTQRNKTLFGEPGNFYI
CCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEE
YLSYGINSCVNIVTGKKNWANGVLLRSIAIKGEHERIASGPGLLAKRFGLNKNFDNLHLS
EEECCCCHHHEEHCCCCCCCCCEEEEEEEECCCHHHHCCCCCHHHHHHCCCCCCCCEEEC
PANDFWLSEGEDLTRMGNIVQTTRIGISQAKDIPWRWYLKSSRSVSKRVRGDRIPPKNKC
CCCCCCCCCCCCHHHHCCHHHHHHCCCHHCCCCCEEEEECCCHHHHHHHCCCCCCCCCCC
WEPSAFEGL
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA