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The map label for this gene is obgE

Identifier: 124025009

GI number: 124025009

Start: 276006

End: 276995

Strand: Direct

Name: obgE

Synonym: NATL1_02961

Alternate gene names: 124025009

Gene position: 276006-276995 (Clockwise)

Preceding gene: 124025008

Following gene: 124025010

Centisome position: 14.8

GC content: 37.78

Gene sequence:

>990_bases
ATGCAATTTATTGATCAGGCTATTATTGATGTCAAAGCAGGTTCGGGTGGTGATGGGATCTCTGCTTTTAGAAGAGAAAA
GTATGTTCCCGCAGGTGGCCCTGCGGGTGGAGATGGAGGACAAGGAGGAAATGTTGTTTTAGAGGCTGATGATAATTTGC
AAACTCTGTTGGATTTCAAATTTCAGAAATTAATTTCTGCGGAGAATGGCCAACGCGGTGGTCCCAATAAATGCACTGGA
GCATCAGGAAAAGACACTGTACTTAAAGTTCCATGCGGAACAGAGGTAAGGCATCTCTCTACAAATATTATTCTTGGTGA
TTTAACTAATAAAGGCCAACAACTTATTGTCGCGTTTGGTGGAAAAGGAGGTTTCGGGAACGCTCGCTATTTATCAAATA
GCAATAGAGCTCCAGAAAAATTTACTGAAGGGAAAGTAGGTGAAGAATGGTCATTGCAATTGGAATTAAAACTTCTAGCA
GAAGTAGGAATTATTGGTTTGCCCAATGCAGGTAAAAGTACTTTGATTTCTGTACTCTCCTCTGCAAGACCAAAGATTGC
TGATTATCCATTTACAACTTTAATTCCAAATCTCGGAGTAGTAAGAAGACCCTCAGGAGATGGAACAGTTTTTGCGGATA
TCCCTGGTTTGATTTCTGGAGCCTCAAAAGGTATTGGATTAGGGCATGATTTTCTTCGGCATATTGAACGAACAAAGGTT
TTGCTTCATTTAATTGACTCAGCATCAACGGACCCGATAAATGATTTCAAAACCATTAATGAGGAATTAACGTCTTACGG
TCATGGTTTGATTTCTAGGCCTAGAATTTTTGTTCTGAATAAAAAAGAACTATTAAATGAGCATGAAATTAAAAAACTTC
TAAATAAAATTGAGAAACTGACTATGAAAAAGGTACATATAATTTCTGCAGTAACGAAATTTGGTCTGGATGATTTGTTG
AGTTCTATTTGGTACGAACTTGGATATTAA

Upstream 100 bases:

>100_bases
AAATTGAGGTGAAAGTTATAAACAGTTTTTTCACTTCTTTAATTTAGCAAGGATGAATTTAAGAATTATTATTTAGTTAA
TTGATTAAAGATATTTCTAA

Downstream 100 bases:

>100_bases
TTAATTGTTATGAGTGAATCATACCTACTTGTCTTACAGTTGTTTCTTGGTCATAACTAAAGAGAGTTATTAAAATTATG
GATTTTTACAGTTGTTTTGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQFIDQAIIDVKAGSGGDGISAFRREKYVPAGGPAGGDGGQGGNVVLEADDNLQTLLDFKFQKLISAENGQRGGPNKCTG
ASGKDTVLKVPCGTEVRHLSTNIILGDLTNKGQQLIVAFGGKGGFGNARYLSNSNRAPEKFTEGKVGEEWSLQLELKLLA
EVGIIGLPNAGKSTLISVLSSARPKIADYPFTTLIPNLGVVRRPSGDGTVFADIPGLISGASKGIGLGHDFLRHIERTKV
LLHLIDSASTDPINDFKTINEELTSYGHGLISRPRIFVLNKKELLNEHEIKKLLNKIEKLTMKKVHIISAVTKFGLDDLL
SSIWYELGY

Sequences:

>Translated_329_residues
MQFIDQAIIDVKAGSGGDGISAFRREKYVPAGGPAGGDGGQGGNVVLEADDNLQTLLDFKFQKLISAENGQRGGPNKCTG
ASGKDTVLKVPCGTEVRHLSTNIILGDLTNKGQQLIVAFGGKGGFGNARYLSNSNRAPEKFTEGKVGEEWSLQLELKLLA
EVGIIGLPNAGKSTLISVLSSARPKIADYPFTTLIPNLGVVRRPSGDGTVFADIPGLISGASKGIGLGHDFLRHIERTKV
LLHLIDSASTDPINDFKTINEELTSYGHGLISRPRIFVLNKKELLNEHEIKKLLNKIEKLTMKKVHIISAVTKFGLDDLL
SSIWYELGY
>Mature_329_residues
MQFIDQAIIDVKAGSGGDGISAFRREKYVPAGGPAGGDGGQGGNVVLEADDNLQTLLDFKFQKLISAENGQRGGPNKCTG
ASGKDTVLKVPCGTEVRHLSTNIILGDLTNKGQQLIVAFGGKGGFGNARYLSNSNRAPEKFTEGKVGEEWSLQLELKLLA
EVGIIGLPNAGKSTLISVLSSARPKIADYPFTTLIPNLGVVRRPSGDGTVFADIPGLISGASKGIGLGHDFLRHIERTKV
LLHLIDSASTDPINDFKTINEELTSYGHGLISRPRIFVLNKKELLNEHEIKKLLNKIEKLTMKKVHIISAVTKFGLDDLL
SSIWYELGY

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=320, Percent_Identity=40, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI111955139, Length=306, Percent_Identity=36.2745098039216, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI111955063, Length=184, Percent_Identity=39.1304347826087, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI58761500, Length=169, Percent_Identity=30.1775147928994, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789574, Length=328, Percent_Identity=50.609756097561, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI1787454, Length=130, Percent_Identity=36.9230769230769, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=37.962962962963, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17552324, Length=311, Percent_Identity=30.5466237942122, Blast_Score=133, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=140, Percent_Identity=32.8571428571429, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=124, Percent_Identity=33.8709677419355, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=138, Percent_Identity=44.2028985507246, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319281, Length=164, Percent_Identity=33.5365853658537, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129375, Length=321, Percent_Identity=37.3831775700935, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585318, Length=237, Percent_Identity=36.2869198312236, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=32.8125, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=32.8125, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=32.8125, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356473, Length=124, Percent_Identity=34.6774193548387, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PROM1 (A2C050)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014125.1
- ProteinModelPortal:   A2C050
- SMR:   A2C050
- STRING:   A2C050
- GeneID:   4780115
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_02961
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   PMAR167555:NATL1_02961-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 35346; Mature: 35346

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDQAIIDVKAGSGGDGISAFRREKYVPAGGPAGGDGGQGGNVVLEADDNLQTLLDFK
CCCHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
FQKLISAENGQRGGPNKCTGASGKDTVLKVPCGTEVRHLSTNIILGDLTNKGQQLIVAFG
HHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHEECEEEEECCCCCCCEEEEEEC
GKGGFGNARYLSNSNRAPEKFTEGKVGEEWSLQLELKLLAEVGIIGLPNAGKSTLISVLS
CCCCCCCCEEECCCCCCCHHHCCCCCCCCEEEEEEEEEHHHCCEEECCCCCHHHHHHHHH
SARPKIADYPFTTLIPNLGVVRRPSGDGTVFADIPGLISGASKGIGLGHDFLRHIERTKV
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHH
LLHLIDSASTDPINDFKTINEELTSYGHGLISRPRIFVLNKKELLNEHEIKKLLNKIEKL
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHCHHHHHHHHHHHHHH
TMKKVHIISAVTKFGLDDLLSSIWYELGY
HHHHHHHHHHHHHHCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFIDQAIIDVKAGSGGDGISAFRREKYVPAGGPAGGDGGQGGNVVLEADDNLQTLLDFK
CCCHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
FQKLISAENGQRGGPNKCTGASGKDTVLKVPCGTEVRHLSTNIILGDLTNKGQQLIVAFG
HHHHHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHEECEEEEECCCCCCCEEEEEEC
GKGGFGNARYLSNSNRAPEKFTEGKVGEEWSLQLELKLLAEVGIIGLPNAGKSTLISVLS
CCCCCCCCEEECCCCCCCHHHCCCCCCCCEEEEEEEEEHHHCCEEECCCCCHHHHHHHHH
SARPKIADYPFTTLIPNLGVVRRPSGDGTVFADIPGLISGASKGIGLGHDFLRHIERTKV
HCCCCCCCCCHHHHCCCCCEEECCCCCCEEEEECCHHHHCCCCCCCCCHHHHHHHHHHHH
LLHLIDSASTDPINDFKTINEELTSYGHGLISRPRIFVLNKKELLNEHEIKKLLNKIEKL
HHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHCHHHHHHHHHHHHHH
TMKKVHIISAVTKFGLDDLLSSIWYELGY
HHHHHHHHHHHHHHCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA