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The map label for this gene is aroK [H]

Identifier: 124024892

GI number: 124024892

Start: 170834

End: 171430

Strand: Direct

Name: aroK [H]

Synonym: NATL1_01791

Alternate gene names: 124024892

Gene position: 170834-171430 (Clockwise)

Preceding gene: 124024884

Following gene: 124024894

Centisome position: 9.16

GC content: 35.51

Gene sequence:

>597_bases
ATGGCTGTCCAATCAACCCCTAAAACTCTTAAAGAAAAGTTAGGTGGTCGAAATATATTTTTGATAGGAATGATGGGTTC
TGGCAAAAGTCAAACGGGTCCAGTTCTAGCAAAAATGATCAATTATGCTTTTGTTGATACTGATGATGTTATAGAAAAAG
CGTCTAAACAATCTATTTCATCTATTTTTGAAAAAGATGGAGAAAAAGTCTTTAGGGATGTTGAAAAAAAAGTTTTAAAA
GAAATTAGTCAACATCATTCTCTTGTAATTGCTACCGGAGGGGGTTTAGTTACCTTGCCTGAAAACTGGGGCATTCTTCA
TCAAGGAATAGTTATTTGGTTAGATCTTGATTTGAGACGTTCAATTAAACGATTAGAAAGTGATCAAAAGAGACGCCCTT
TACTACTTGGGGATAATTTAGCTGAGAATTTTAGTCAGATTTATGAAAGTAGAAAACCAATATATTTAGAGTCAGATTTG
AGAATAGAAGTTGAGGATCAATCACCATATGAGGTCGCTACTATGGTTGCTGAACATTTGCCAAGCATCCTTATTGACCC
GGAGACTCAAGCCGAACGGCATACCACTGAATTGTAA

Upstream 100 bases:

>100_bases
ACAGGTTCTCCCCTCTCCGTGAGGGAAATTCGATGTGATTGCTTCCATAAATTTTTCACATCAACATACATCTTAATAAC
TTTTAGTTACTTCTGTCTTT

Downstream 100 bases:

>100_bases
AACCTGTTTTGATTTCTAAGTCGCAGGCTGTATCAAGTAAATGTTGAGCCGCTTCTGCTATTGAAGACTTACAGTCAAGA
TCCAATGGTAATGAATCGAA

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAVQSTPKTLKEKLGGRNIFLIGMMGSGKSQTGPVLAKMINYAFVDTDDVIEKASKQSISSIFEKDGEKVFRDVEKKVLK
EISQHHSLVIATGGGLVTLPENWGILHQGIVIWLDLDLRRSIKRLESDQKRRPLLLGDNLAENFSQIYESRKPIYLESDL
RIEVEDQSPYEVATMVAEHLPSILIDPETQAERHTTEL

Sequences:

>Translated_198_residues
MAVQSTPKTLKEKLGGRNIFLIGMMGSGKSQTGPVLAKMINYAFVDTDDVIEKASKQSISSIFEKDGEKVFRDVEKKVLK
EISQHHSLVIATGGGLVTLPENWGILHQGIVIWLDLDLRRSIKRLESDQKRRPLLLGDNLAENFSQIYESRKPIYLESDL
RIEVEDQSPYEVATMVAEHLPSILIDPETQAERHTTEL
>Mature_197_residues
AVQSTPKTLKEKLGGRNIFLIGMMGSGKSQTGPVLAKMINYAFVDTDDVIEKASKQSISSIFEKDGEKVFRDVEKKVLKE
ISQHHSLVIATGGGLVTLPENWGILHQGIVIWLDLDLRRSIKRLESDQKRRPLLLGDNLAENFSQIYESRKPIYLESDLR
IEVEDQSPYEVATMVAEHLPSILIDPETQAERHTTEL

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=36.9047619047619, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1786587, Length=142, Percent_Identity=33.0985915492958, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 22299; Mature: 22168

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVQSTPKTLKEKLGGRNIFLIGMMGSGKSQTGPVLAKMINYAFVDTDDVIEKASKQSIS
CCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SIFEKDGEKVFRDVEKKVLKEISQHHSLVIATGGGLVTLPENWGILHQGIVIWLDLDLRR
HHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCHHHCCEEEEEEHHHHH
SIKRLESDQKRRPLLLGDNLAENFSQIYESRKPIYLESDLRIEVEDQSPYEVATMVAEHL
HHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCEEEECCCEEEECCCCCHHHHHHHHHHC
PSILIDPETQAERHTTEL
CCEEECCCCHHHHHCCCC
>Mature Secondary Structure 
AVQSTPKTLKEKLGGRNIFLIGMMGSGKSQTGPVLAKMINYAFVDTDDVIEKASKQSIS
CCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SIFEKDGEKVFRDVEKKVLKEISQHHSLVIATGGGLVTLPENWGILHQGIVIWLDLDLRR
HHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCHHHCCEEEEEEHHHHH
SIKRLESDQKRRPLLLGDNLAENFSQIYESRKPIYLESDLRIEVEDQSPYEVATMVAEHL
HHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCEEEECCCEEEECCCCCHHHHHHHHHHC
PSILIDPETQAERHTTEL
CCEEECCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA