Click here to switch to the map view.

The map label for this gene is csgA [H]

Identifier: 124024820

GI number: 124024820

Start: 104698

End: 105363

Strand: Direct

Name: csgA [H]

Synonym: NATL1_01071

Alternate gene names: 124024820

Gene position: 104698-105363 (Clockwise)

Preceding gene: 124024819

Following gene: 124024822

Centisome position: 5.61

GC content: 36.19

Gene sequence:

>666_bases
TTGACTACTTATTTAATTACTGGATCCAACAGAGGTATAGGTTTAGAACTTGTTCGTCAATTGAAGGATAGAGGAGACGA
TGTTATCGCCACTTGTAGATCGGCTTCGCCAGAATTAAATTCCTTGTCAGTAAGAGTTGAGACAAATATTGATATCACTT
CAGGGGACTCTGTTGTTAAGCTCAGAGATAATTTAAAAGATAATAGCGTAGATGTTTTGATTCAAAATGCTGGAATTGCT
GAATTTAATTCGCTTTCTAACTTAGACCCGCAAAGTATCGTTCATCAATTTGAGGTAAATGCATTAAGTCCTTTGTGTTG
TGTACATACTTTGCTTAGTAAGCTCAGCAAATCTGCAAAAATAGCTTTAATAAGTAGTCGTATGGGTTCAATAGAGGATA
ATAATTCTGGCGGTTCCTATGGATATAGGATGTCAAAAGTTGCTTTATGTATGGCTGGCAAATCTTTATCAGTTGATTTA
ATGCCTAGGGGTATTTCGGTTGGAATTTTACATCCAGGTTTAGTCAGTACTCGAATGACAGGATTTACTTCCAATGGCAT
TCAACCTAAAGAATCAGTCAAAGGACTGATTCAAAGAATTGATGAACTTACACTTGAAAATACAGGTAACTTCTGGCATT
CAAATGGTGAGATCTTGCCATGGTAA

Upstream 100 bases:

>100_bases
ATAATTATTGTGAGGTTCAGATTCTTATTATGTATCAATTCGAATGATTTTTCTTAGTTTGATTTATTTGTTTTAGGCTT
GTGGAAGCTAAAGGTTTATT

Downstream 100 bases:

>100_bases
AAGATTCTTTCTATAATTTTGATCGATTTTTTATATTGAAATACTGAATACTTTACAAATTGATTTGTCGCTTTAAGTTA
TATCCTTCCTAGTGTTTTTC

Product: Short-chain dehydrogenases of various substrate specificities

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTTYLITGSNRGIGLELVRQLKDRGDDVIATCRSASPELNSLSVRVETNIDITSGDSVVKLRDNLKDNSVDVLIQNAGIA
EFNSLSNLDPQSIVHQFEVNALSPLCCVHTLLSKLSKSAKIALISSRMGSIEDNNSGGSYGYRMSKVALCMAGKSLSVDL
MPRGISVGILHPGLVSTRMTGFTSNGIQPKESVKGLIQRIDELTLENTGNFWHSNGEILPW

Sequences:

>Translated_221_residues
MTTYLITGSNRGIGLELVRQLKDRGDDVIATCRSASPELNSLSVRVETNIDITSGDSVVKLRDNLKDNSVDVLIQNAGIA
EFNSLSNLDPQSIVHQFEVNALSPLCCVHTLLSKLSKSAKIALISSRMGSIEDNNSGGSYGYRMSKVALCMAGKSLSVDL
MPRGISVGILHPGLVSTRMTGFTSNGIQPKESVKGLIQRIDELTLENTGNFWHSNGEILPW
>Mature_220_residues
TTYLITGSNRGIGLELVRQLKDRGDDVIATCRSASPELNSLSVRVETNIDITSGDSVVKLRDNLKDNSVDVLIQNAGIAE
FNSLSNLDPQSIVHQFEVNALSPLCCVHTLLSKLSKSAKIALISSRMGSIEDNNSGGSYGYRMSKVALCMAGKSLSVDLM
PRGISVGILHPGLVSTRMTGFTSNGIQPKESVKGLIQRIDELTLENTGNFWHSNGEILPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=32.2404371584699, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI2367365, Length=178, Percent_Identity=28.0898876404494, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=30.6451612903226, Blast_Score=62, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72001658, Length=244, Percent_Identity=34.4262295081967, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17559962, Length=246, Percent_Identity=34.1463414634146, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558994, Length=242, Percent_Identity=30.5785123966942, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI193207563, Length=239, Percent_Identity=28.4518828451883, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17559964, Length=243, Percent_Identity=30.8641975308642, Blast_Score=73, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17558992, Length=246, Percent_Identity=32.1138211382114, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558006, Length=202, Percent_Identity=31.6831683168317, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17541382, Length=251, Percent_Identity=31.0756972111554, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558996, Length=248, Percent_Identity=27.0161290322581, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17558990, Length=247, Percent_Identity=26.7206477732794, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532177, Length=237, Percent_Identity=29.957805907173, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322779, Length=244, Percent_Identity=29.5081967213115, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24640547, Length=249, Percent_Identity=34.5381526104418, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24643142, Length=181, Percent_Identity=33.1491712707182, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23877; Mature: 23745

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYLITGSNRGIGLELVRQLKDRGDDVIATCRSASPELNSLSVRVETNIDITSGDSVVK
CEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECEEEECCCCEEE
LRDNLKDNSVDVLIQNAGIAEFNSLSNLDPQSIVHQFEVNALSPLCCVHTLLSKLSKSAK
EECCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCE
IALISSRMGSIEDNNSGGSYGYRMSKVALCMAGKSLSVDLMPRGISVGILHPGLVSTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHEEEEECCCCCEEEEECCCCEEEEECCCHHHHEEC
GFTSNGIQPKESVKGLIQRIDELTLENTGNFWHSNGEILPW
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC
>Mature Secondary Structure 
TTYLITGSNRGIGLELVRQLKDRGDDVIATCRSASPELNSLSVRVETNIDITSGDSVVK
EEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEEECEEEECCCCEEE
LRDNLKDNSVDVLIQNAGIAEFNSLSNLDPQSIVHQFEVNALSPLCCVHTLLSKLSKSAK
EECCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCE
IALISSRMGSIEDNNSGGSYGYRMSKVALCMAGKSLSVDLMPRGISVGILHPGLVSTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHEEEEECCCCCEEEEECCCCEEEEECCCHHHHEEC
GFTSNGIQPKESVKGLIQRIDELTLENTGNFWHSNGEILPW
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]