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The map label for this gene is thiL [H]

Identifier: 124024736

GI number: 124024736

Start: 25758

End: 26747

Strand: Reverse

Name: thiL [H]

Synonym: NATL1_00231

Alternate gene names: 124024736

Gene position: 26747-25758 (Counterclockwise)

Preceding gene: 124024737

Following gene: 124024734

Centisome position: 1.43

GC content: 34.95

Gene sequence:

>990_bases
GTGACAACTACTATTCAAGATTTAGGTGAAATAGAATTACTAAATCGTTTAAAAAAATTTATGCGCTGTGGACAAATAGA
TGATGATGTCGCAGAAATAAATAAAATAAATAAAAGCTTATTAATTAATACTGATTTACTTGTAGAAAAAATTCATTTTT
CTGATGAAATATCTAATGCTAAAGATATTGGCTGGAAATGTATTACTACAAATATTTCTGATCTTATTTGCAGCGGCTCA
GAAAATATAATTTCCTTTACTGTTGGACTTGTTTTGCCGCCAAACACACATTGGAAATGGGTTGAAAATCTATATGAAGG
AATGTTGGAAGCGATGCAAGAATTTGGAGGAGAAATAATCGGTGGAGATTGCTCGTGCGGAGAAACAAAAATGATTTCAA
TTACAGCAATTGGAGAAATGAATCTCCCCAGACTACATAGAGGAAATGCTTTACCTGGAGATTACATTGTTAGCACTGGA
ATCCATGGATTAAGTAGGCTAGGCTTGGCACTTTTAACATCCGAGAAACTACCAAGTGAAGCCCCAGTAAGTCCTAAGCT
AATTAATAAGGCTATCAACGCACACAAACGCCCCTATCCTGCTTTAAAAGCACTCAAAGCTTTAAAAGCTTGTAAACCTC
AATCAACAAGTTGGAGAGCCGCAGGGACTGATAGCAGCGATGGACTAATTGAATCAATTAGAGGAATTTGCCAAGCAAGT
AATTGTCAAGCAATTTTATCAAAAACTTCTATTCTCAAACATCCTGACTGGCCAGAAGATGATATTTGGGATGAATGGAT
CCTGAATGGGGGTGAGGACTATGAATTAATACTGAGTCTTCCTAAAGACTGGGCAAAGTCATTATCAAATAAATTAAAAT
CTGCCAAAATTATTGGGTTTATCAAAGAAGGTAAACCCAATATTTTCTGGGATAATTTAGAACAAACTAGAATTGACCAA
TCAAGTCTATTTAGACATTTTAAACTCTAG

Upstream 100 bases:

>100_bases
AGAAATATTAAATAAACTTGGAGTAGATGATAAAATCATATCGATTACAGTATTAAATGGTTCAGAAAATCTAAAACTCA
AAGCTTAAATTCGAAATAAA

Downstream 100 bases:

>100_bases
AAGTTAATTTTACTTCCATTTCTGAGCAACAATTTCAGCCAAATCAACAACCCTTTGACTGTAACCCCACTCATTGTCAT
ACCAAGCTAAAACTTTCACC

Product: putative thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTTTIQDLGEIELLNRLKKFMRCGQIDDDVAEINKINKSLLINTDLLVEKIHFSDEISNAKDIGWKCITTNISDLICSGS
ENIISFTVGLVLPPNTHWKWVENLYEGMLEAMQEFGGEIIGGDCSCGETKMISITAIGEMNLPRLHRGNALPGDYIVSTG
IHGLSRLGLALLTSEKLPSEAPVSPKLINKAINAHKRPYPALKALKALKACKPQSTSWRAAGTDSSDGLIESIRGICQAS
NCQAILSKTSILKHPDWPEDDIWDEWILNGGEDYELILSLPKDWAKSLSNKLKSAKIIGFIKEGKPNIFWDNLEQTRIDQ
SSLFRHFKL

Sequences:

>Translated_329_residues
MTTTIQDLGEIELLNRLKKFMRCGQIDDDVAEINKINKSLLINTDLLVEKIHFSDEISNAKDIGWKCITTNISDLICSGS
ENIISFTVGLVLPPNTHWKWVENLYEGMLEAMQEFGGEIIGGDCSCGETKMISITAIGEMNLPRLHRGNALPGDYIVSTG
IHGLSRLGLALLTSEKLPSEAPVSPKLINKAINAHKRPYPALKALKALKACKPQSTSWRAAGTDSSDGLIESIRGICQAS
NCQAILSKTSILKHPDWPEDDIWDEWILNGGEDYELILSLPKDWAKSLSNKLKSAKIIGFIKEGKPNIFWDNLEQTRIDQ
SSLFRHFKL
>Mature_328_residues
TTTIQDLGEIELLNRLKKFMRCGQIDDDVAEINKINKSLLINTDLLVEKIHFSDEISNAKDIGWKCITTNISDLICSGSE
NIISFTVGLVLPPNTHWKWVENLYEGMLEAMQEFGGEIIGGDCSCGETKMISITAIGEMNLPRLHRGNALPGDYIVSTGI
HGLSRLGLALLTSEKLPSEAPVSPKLINKAINAHKRPYPALKALKALKACKPQSTSWRAAGTDSSDGLIESIRGICQASN
CQAILSKTSILKHPDWPEDDIWDEWILNGGEDYELILSLPKDWAKSLSNKLKSAKIIGFIKEGKPNIFWDNLEQTRIDQS
SLFRHFKL

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=325, Percent_Identity=30.7692307692308, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 36543; Mature: 36412

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTIQDLGEIELLNRLKKFMRCGQIDDDVAEINKINKSLLINTDLLVEKIHFSDEISNA
CCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHEECHHHHHHHHHHHHHHCCH
KDIGWKCITTNISDLICSGSENIISFTVGLVLPPNTHWKWVENLYEGMLEAMQEFGGEII
HHCCCEEEECCHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEE
GGDCSCGETKMISITAIGEMNLPRLHRGNALPGDYIVSTGIHGLSRLGLALLTSEKLPSE
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
APVSPKLINKAINAHKRPYPALKALKALKACKPQSTSWRAAGTDSSDGLIESIRGICQAS
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCCC
NCQAILSKTSILKHPDWPEDDIWDEWILNGGEDYELILSLPKDWAKSLSNKLKSAKIIGF
CHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEE
IKEGKPNIFWDNLEQTRIDQSSLFRHFKL
EECCCCCCEECCCHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
TTTIQDLGEIELLNRLKKFMRCGQIDDDVAEINKINKSLLINTDLLVEKIHFSDEISNA
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHEECHHHHHHHHHHHHHHCCH
KDIGWKCITTNISDLICSGSENIISFTVGLVLPPNTHWKWVENLYEGMLEAMQEFGGEII
HHCCCEEEECCHHHHHHCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEE
GGDCSCGETKMISITAIGEMNLPRLHRGNALPGDYIVSTGIHGLSRLGLALLTSEKLPSE
CCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
APVSPKLINKAINAHKRPYPALKALKALKACKPQSTSWRAAGTDSSDGLIESIRGICQAS
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHCCC
NCQAILSKTSILKHPDWPEDDIWDEWILNGGEDYELILSLPKDWAKSLSNKLKSAKIIGF
CHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHEEEE
IKEGKPNIFWDNLEQTRIDQSSLFRHFKL
EECCCCCCEECCCHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA