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The map label for this gene is crp [C]

Identifier: 124024520

GI number: 124024520

Start: 2496689

End: 2497384

Strand: Reverse

Name: crp [C]

Synonym: P9303_28321

Alternate gene names: 124024520

Gene position: 2497384-2496689 (Counterclockwise)

Preceding gene: 124024525

Following gene: 124024518

Centisome position: 93.09

GC content: 52.44

Gene sequence:

>696_bases
ATGGCTGTTTTCAGCGTTGAGCAGTTGCAGGCTGTGCAATTTTTTTCGGCTTTAACAACGGATGATTGTGAGCAATTATT
GGATCGCCATCTTGAGTCCATTCATGGTGCTGAACAGGTTTTCGTGATGGAGCAAGACTGGGGTGAGTCGGTTTTTCTGT
TGTGCTCAGGGATGGCGAAAGTACGCAGTTATACGGCTGATGGCGATGAAGTTGTGATGTCAGTGTTGGGGGAGGGGGAC
CTGTTTGGTGAGATGGCTGCTCTTGATGCAGCACCCAGGTCTGCTGATGTTGTGGCCTTAACGCCAGTGAAACTTTTGAA
GATGAGAGCGTCGCCTTTTGTGGCTTTGCTGCGCAAGGAAGTGGGCTTTGCGATTGCCCTTGCTCAGCTTGAGGCATCTC
GCTTGCGGGATCTCAATCAGCGTTTTGCAATCCAGACCAGTGATGCCACGACACGCTTACTCAATGCATTGGCTTACTTG
GCTCGCAAGAGTTCTTCTGCTGATGATCCCAAAGCGGCGATTCCGCCCTTAGCTCAAAGGGAGTTGGGTCTCATGGCAGG
TTTGTCCAGGGAGACTGCCTCCCGGACATTGAGCAAGCTGCGCAGTCGTGGAACACTGGAGGAGGTTGAAGGCTGTCTGC
GTTTGGTGGATCTGCAGCCGCTGGTTAAACGAGGTCTGTTGCCGCTTGGCTCTTAG

Upstream 100 bases:

>100_bases
TAGTGTGTGAGTGAAGGTTGACTAATGTGCAAATAAATGATTCATATTGAAGAGTGATTTAGGGGTTGCATTATTGTTCA
ATAACTAAAAATAATGAAAC

Downstream 100 bases:

>100_bases
AGCTTTTGAGCACGTTTACGGGTTGAATTGACCAGCCAGAATCGTCTTAGACTTAGGACTGTTAGGAAAGCTTTCAGAAA
AACAAGTTGCTGATCTCGAG

Product: regulatory protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Catabolite Gene Activator; CAMP-Dependent Transcriptional Regulator; Cyclic AMP Receptor Protein; Catabolite Gene Activator Protein; Regulatory Protein; CAMP Receptor Protein; CAMP-Dependent Protein Kinase; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MAVFSVEQLQAVQFFSALTTDDCEQLLDRHLESIHGAEQVFVMEQDWGESVFLLCSGMAKVRSYTADGDEVVMSVLGEGD
LFGEMAALDAAPRSADVVALTPVKLLKMRASPFVALLRKEVGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYL
ARKSSSADDPKAAIPPLAQRELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGS

Sequences:

>Translated_231_residues
MAVFSVEQLQAVQFFSALTTDDCEQLLDRHLESIHGAEQVFVMEQDWGESVFLLCSGMAKVRSYTADGDEVVMSVLGEGD
LFGEMAALDAAPRSADVVALTPVKLLKMRASPFVALLRKEVGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYL
ARKSSSADDPKAAIPPLAQRELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGS
>Mature_230_residues
AVFSVEQLQAVQFFSALTTDDCEQLLDRHLESIHGAEQVFVMEQDWGESVFLLCSGMAKVRSYTADGDEVVMSVLGEGDL
FGEMAALDAAPRSADVVALTPVKLLKMRASPFVALLRKEVGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYLA
RKSSSADDPKAAIPPLAQRELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGS

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25079; Mature: 24948

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVFSVEQLQAVQFFSALTTDDCEQLLDRHLESIHGAEQVFVMEQDWGESVFLLCSGMAK
CCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
VRSYTADGDEVVMSVLGEGDLFGEMAALDAAPRSADVVALTPVKLLKMRASPFVALLRKE
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHCCHHHHHHHHH
VGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYLARKSSSADDPKAAIPPLAQR
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGS
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AVFSVEQLQAVQFFSALTTDDCEQLLDRHLESIHGAEQVFVMEQDWGESVFLLCSGMAK
CCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHH
VRSYTADGDEVVMSVLGEGDLFGEMAALDAAPRSADVVALTPVKLLKMRASPFVALLRKE
HHHCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEECHHHHHHHHCCHHHHHHHHH
VGFAIALAQLEASRLRDLNQRFAIQTSDATTRLLNALAYLARKSSSADDPKAAIPPLAQR
HHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
ELGLMAGLSRETASRTLSKLRSRGTLEEVEGCLRLVDLQPLVKRGLLPLGS
HHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA