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The map label for this gene is argS [H]

Identifier: 124024435

GI number: 124024435

Start: 2417650

End: 2419461

Strand: Reverse

Name: argS [H]

Synonym: P9303_27471

Alternate gene names: 124024435

Gene position: 2419461-2417650 (Counterclockwise)

Preceding gene: 124024437

Following gene: 124024434

Centisome position: 90.19

GC content: 55.13

Gene sequence:

>1812_bases
ATGCTCAGCCTTGCCCACGCTCTGGAGAGTCAACTGCGTGCGGCCATCGACCGTGCCTTCCCTGAAGCCGCAGCCTCAGC
ACGTGAGAGTGGCACTGGCTTGGATCCACAATTGGCCCCAGCCAGCAAGCCTGAATTTGGTGATTTTCAGGCCAATGCTG
CCTTACCCCTCGCTAAGCCGCTTAAGCAGCCTCCGCGTCAAATTGCTGCAGCGATTGTCGACCAGCTGATGGTCGATACG
GCATTCAATGCCATTTGCTTGACGCCAGACATTGCCGGGCCAGGTTTCATTAATCTCACCGTGCGGCCCGAATGTCTGGC
TGCTGAAGTGCAGGCAAGGTTGGCTGATGCTCGTTTGGGCGTGCCGCTGGTGGAGGGCGATAACGATGGGCAACAGCCCA
CTCCAGTGGTGGTGGATTTCTCCAGCCCCAACATCGCCAAGGAGATGCATGTGGGGCACTTGCGTTCCACGATCATTGGC
GATTCCCTCGCTCGGGTGTTGGAGTTTCGTGGACACCCCGTGCTGCGTCTTAACCATGTAGGCGATTGGGGTACGCAATT
TGGGATGTTGATTACCCACTTGAAGCAAGTGGCGCCAGAGGCTCTTGAAACAGCTGATGCTGTTGATCTTGGTGATCTTG
TGGTGTTTTATCGCCAGGCGAAGCAACGCTTTGATGACGACGAGGCTTTTCAGACCACCTCCCGTGAGGAGGTGGTGAAA
TTGCAAGGGGGTGATCCTCTTTCCTTGAAGGCTTGGAGTTTGCTATGTGATCAGTCGCGCCGTGAATTTCAAAAGATCTA
CGATCGGCTTGATGTTCGTCTCAACGAGCGCGGCGAATCGTTTTACAATGCCTATCTCGAGAGCGTCGTTGAGGATCTCA
ATGTCTCCGGTTTGCTCGTTAGCGATGACGGCGCTCAGTGTGTCTTCCTTGAGGGTGTTACGGGTAAGGACGGCAAACCT
CTGCCTGTGATTGTTCAGAAGAGTGATGGTGGCTTCAATTACGCCACCACCGATCTGGCAGCCATGCGCTATCGCTTTGC
TGCTCCTCCCCAAGGTGATGGCGCTCGGCGTGTGATTTACGTGACCGATGCTGGCCAGGCCAATCATTTCGCTGGCGTCT
TTCAGGTTGCTCAGCGCGCAGGTTGGATCCCTGATGCTGGACGTCTCCAGCACGTGCCTTTTGGCTTGGTTCAGGGGGAA
GATGGCAAGAAGCTCAAAACGCGTGCTGGTGACACTGTTCGTCTGCGCGAGTTACTCGATGAGGCTGTTGAGCGCGCTGA
GTCTGATCTGCGCCGTCGGCTGCAGGAGGAGGGTCGGGATGAAGATGAATCTTTTATTGAGCAGGTGGCCACCACGGTGG
GGCTGGCAGCAGTGAAGTATGCCGATCTCAGCCAGAACCGAATCACCAACTACCAGTTCAGTTTTGATCGCATGCTTGCT
CTGCAGGGCAATACAGCTCCCTATCTGCTTTATGCCGTTGTTCGTATCGCCGGTATTGCGCGCAAGGGGGGCGATCTTGA
TGTCACTACGGCTGAGCTTCAGTTCAGTGAAACGCAGGAATGGGCTTTAGTGCGTGAGTTACTCAAGTTTGATGCAGTGA
TCGCCGAAGTTGAGGAGGAGTTGTTACCCAATCGTCTCTGCACCTATCTGTTTGAGCTCAGCCAGGTGTTTAATCGCTTT
TACGATCAGGTGCCGGTGTTGAAGGCTGAGCAACCATCTCGTAGCTGTCGCCTAGCGCTCTGCCGGCTCACGGCAGATAC
CCTAAAACTAGGGCTGTCGTTGTTGGGTATTCCCACGCTGGAGCGGATGTGA

Upstream 100 bases:

>100_bases
GGTGATCGCTTGAGAACAGTGCTGAACCAGGCTTGCTGGTTGCCGGCATCGTGGTCAGTGATGATCAGGGTGATTGCAGG
CCCATTTCGCTTCGGAGTTC

Downstream 100 bases:

>100_bases
TGGGGTCTTCACCTGCACGAATGAGTTCTGGTGCCCCCGCTCCTCGGGTGGAAGTGGAGTGTCTGAAGGCCTATAGCGCT
CCGCTTGAGGGTCGCCGTGG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MLSLAHALESQLRAAIDRAFPEAAASARESGTGLDPQLAPASKPEFGDFQANAALPLAKPLKQPPRQIAAAIVDQLMVDT
AFNAICLTPDIAGPGFINLTVRPECLAAEVQARLADARLGVPLVEGDNDGQQPTPVVVDFSSPNIAKEMHVGHLRSTIIG
DSLARVLEFRGHPVLRLNHVGDWGTQFGMLITHLKQVAPEALETADAVDLGDLVVFYRQAKQRFDDDEAFQTTSREEVVK
LQGGDPLSLKAWSLLCDQSRREFQKIYDRLDVRLNERGESFYNAYLESVVEDLNVSGLLVSDDGAQCVFLEGVTGKDGKP
LPVIVQKSDGGFNYATTDLAAMRYRFAAPPQGDGARRVIYVTDAGQANHFAGVFQVAQRAGWIPDAGRLQHVPFGLVQGE
DGKKLKTRAGDTVRLRELLDEAVERAESDLRRRLQEEGRDEDESFIEQVATTVGLAAVKYADLSQNRITNYQFSFDRMLA
LQGNTAPYLLYAVVRIAGIARKGGDLDVTTAELQFSETQEWALVRELLKFDAVIAEVEEELLPNRLCTYLFELSQVFNRF
YDQVPVLKAEQPSRSCRLALCRLTADTLKLGLSLLGIPTLERM

Sequences:

>Translated_603_residues
MLSLAHALESQLRAAIDRAFPEAAASARESGTGLDPQLAPASKPEFGDFQANAALPLAKPLKQPPRQIAAAIVDQLMVDT
AFNAICLTPDIAGPGFINLTVRPECLAAEVQARLADARLGVPLVEGDNDGQQPTPVVVDFSSPNIAKEMHVGHLRSTIIG
DSLARVLEFRGHPVLRLNHVGDWGTQFGMLITHLKQVAPEALETADAVDLGDLVVFYRQAKQRFDDDEAFQTTSREEVVK
LQGGDPLSLKAWSLLCDQSRREFQKIYDRLDVRLNERGESFYNAYLESVVEDLNVSGLLVSDDGAQCVFLEGVTGKDGKP
LPVIVQKSDGGFNYATTDLAAMRYRFAAPPQGDGARRVIYVTDAGQANHFAGVFQVAQRAGWIPDAGRLQHVPFGLVQGE
DGKKLKTRAGDTVRLRELLDEAVERAESDLRRRLQEEGRDEDESFIEQVATTVGLAAVKYADLSQNRITNYQFSFDRMLA
LQGNTAPYLLYAVVRIAGIARKGGDLDVTTAELQFSETQEWALVRELLKFDAVIAEVEEELLPNRLCTYLFELSQVFNRF
YDQVPVLKAEQPSRSCRLALCRLTADTLKLGLSLLGIPTLERM
>Mature_603_residues
MLSLAHALESQLRAAIDRAFPEAAASARESGTGLDPQLAPASKPEFGDFQANAALPLAKPLKQPPRQIAAAIVDQLMVDT
AFNAICLTPDIAGPGFINLTVRPECLAAEVQARLADARLGVPLVEGDNDGQQPTPVVVDFSSPNIAKEMHVGHLRSTIIG
DSLARVLEFRGHPVLRLNHVGDWGTQFGMLITHLKQVAPEALETADAVDLGDLVVFYRQAKQRFDDDEAFQTTSREEVVK
LQGGDPLSLKAWSLLCDQSRREFQKIYDRLDVRLNERGESFYNAYLESVVEDLNVSGLLVSDDGAQCVFLEGVTGKDGKP
LPVIVQKSDGGFNYATTDLAAMRYRFAAPPQGDGARRVIYVTDAGQANHFAGVFQVAQRAGWIPDAGRLQHVPFGLVQGE
DGKKLKTRAGDTVRLRELLDEAVERAESDLRRRLQEEGRDEDESFIEQVATTVGLAAVKYADLSQNRITNYQFSFDRMLA
LQGNTAPYLLYAVVRIAGIARKGGDLDVTTAELQFSETQEWALVRELLKFDAVIAEVEEELLPNRLCTYLFELSQVFNRF
YDQVPVLKAEQPSRSCRLALCRLTADTLKLGLSLLGIPTLERM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=625, Percent_Identity=40.16, Blast_Score=440, Evalue=1e-123,
Organism=Homo sapiens, GI197100773, Length=578, Percent_Identity=32.6989619377163, Blast_Score=238, Evalue=1e-62,
Organism=Escherichia coli, GI1788184, Length=576, Percent_Identity=45.4861111111111, Blast_Score=480, Evalue=1e-136,
Organism=Caenorhabditis elegans, GI71985061, Length=622, Percent_Identity=39.0675241157556, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI71985068, Length=586, Percent_Identity=39.5904436860068, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17532153, Length=486, Percent_Identity=27.3662551440329, Blast_Score=131, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6320548, Length=532, Percent_Identity=32.1428571428571, Blast_Score=213, Evalue=9e-56,
Organism=Saccharomyces cerevisiae, GI6321883, Length=495, Percent_Identity=30.9090909090909, Blast_Score=196, Evalue=6e-51,
Organism=Drosophila melanogaster, GI18859963, Length=626, Percent_Identity=40.8945686900958, Blast_Score=437, Evalue=1e-123,
Organism=Drosophila melanogaster, GI28571570, Length=526, Percent_Identity=29.467680608365, Blast_Score=177, Evalue=2e-44,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 66380; Mature: 66380

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLAHALESQLRAAIDRAFPEAAASARESGTGLDPQLAPASKPEFGDFQANAALPLAKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LKQPPRQIAAAIVDQLMVDTAFNAICLTPDIAGPGFINLTVRPECLAAEVQARLADARLG
HCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
VPLVEGDNDGQQPTPVVVDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFRGHPVLRLNHV
CEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GDWGTQFGMLITHLKQVAPEALETADAVDLGDLVVFYRQAKQRFDDDEAFQTTSREEVVK
CCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHEEE
LQGGDPLSLKAWSLLCDQSRREFQKIYDRLDVRLNERGESFYNAYLESVVEDLNVSGLLV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCCEEEE
SDDGAQCVFLEGVTGKDGKPLPVIVQKSDGGFNYATTDLAAMRYRFAAPPQGDGARRVIY
ECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
VTDAGQANHFAGVFQVAQRAGWIPDAGRLQHVPFGLVQGEDGKKLKTRAGDTVRLRELLD
EECCCCCHHHHHHHHHHHHCCCCCCCCCEECCCEEEEECCCCCCHHHCCCCHHHHHHHHH
EAVERAESDLRRRLQEEGRDEDESFIEQVATTVGLAAVKYADLSQNRITNYQFSFDRMLA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEEE
LQGNTAPYLLYAVVRIAGIARKGGDLDVTTAELQFSETQEWALVRELLKFDAVIAEVEEE
ECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLPNRLCTYLFELSQVFNRFYDQVPVLKAEQPSRSCRLALCRLTADTLKLGLSLLGIPTL
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ERM
CCC
>Mature Secondary Structure
MLSLAHALESQLRAAIDRAFPEAAASARESGTGLDPQLAPASKPEFGDFQANAALPLAKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LKQPPRQIAAAIVDQLMVDTAFNAICLTPDIAGPGFINLTVRPECLAAEVQARLADARLG
HCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
VPLVEGDNDGQQPTPVVVDFSSPNIAKEMHVGHLRSTIIGDSLARVLEFRGHPVLRLNHV
CEEEECCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
GDWGTQFGMLITHLKQVAPEALETADAVDLGDLVVFYRQAKQRFDDDEAFQTTSREEVVK
CCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHCCCHHHEEE
LQGGDPLSLKAWSLLCDQSRREFQKIYDRLDVRLNERGESFYNAYLESVVEDLNVSGLLV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHCCCCEEEE
SDDGAQCVFLEGVTGKDGKPLPVIVQKSDGGFNYATTDLAAMRYRFAAPPQGDGARRVIY
ECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
VTDAGQANHFAGVFQVAQRAGWIPDAGRLQHVPFGLVQGEDGKKLKTRAGDTVRLRELLD
EECCCCCHHHHHHHHHHHHCCCCCCCCCEECCCEEEEECCCCCCHHHCCCCHHHHHHHHH
EAVERAESDLRRRLQEEGRDEDESFIEQVATTVGLAAVKYADLSQNRITNYQFSFDRMLA
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEEE
LQGNTAPYLLYAVVRIAGIARKGGDLDVTTAELQFSETQEWALVRELLKFDAVIAEVEEE
ECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLPNRLCTYLFELSQVFNRFYDQVPVLKAEQPSRSCRLALCRLTADTLKLGLSLLGIPTL
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHH
ERM
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]