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The map label for this gene is yfjD [C]

Identifier: 124024183

GI number: 124024183

Start: 2190860

End: 2192143

Strand: Reverse

Name: yfjD [C]

Synonym: P9303_24941

Alternate gene names: 124024183

Gene position: 2192143-2190860 (Counterclockwise)

Preceding gene: 124024184

Following gene: 124024182

Centisome position: 81.71

GC content: 54.28

Gene sequence:

>1284_bases
ATGAGGTTGCTTTTCCTGGCTGTATTGCTGGTTCTACCGGCTTTTTTCGCGGCTGGAGAGGTTGCCTTGTTGCGGCTGCG
GCCTAGTCGAGTACAGGTTTTAGTGGAAGAGCAGCAGCCCGGAGCTTCCGCCGTTCATCGTCTTCAGCGCCGTTTGAGGA
GGGCGTTGATGGTGTCTCAACTGGGTGGAATGCTGGCGTTGGTAGCCCTGGGCTGGGTTGGCCGTGGTGTTGGACATCGC
TGGTGGCCTCTAGCTGATCCTGCTAGTCGCTGGTTGGACGGGGGGCTTTTTCTGCTGCTTGTGGTGTTGGCCACCTTGTT
GGCTGGTTTTCTTCCTAAGGCCTGGGTGCTGAACCGTCCAGAGGCTTCAGCTCTAAACCTCGCTCCATTGTTGGAGATGG
TGATGCGTGTGCTTGCTCCCCTTTTGGCTCTTCTGGAAGCTGTCGCTTCGATGATGTTACGGCTGGTTGGTTTGAATGCA
CATTGGGATTCTCTTGTTCCTGCTCTCTCTGCTGGTGAGCTGGAGTCTCTGATCGAAATTGGCGGTGTAACAGGCCTTCG
TCCTGATGAGCGCAACATCCTTGAAGGTGTTTTTGCCTTGCGCGACACTCAAGTTAGAGAGGTGATGGTGCCACGTTCTG
GCATGGTCACCTTGCCTGTTGGGGTCTGCTTCGCTGAACTGATGAGAGTGGTGCATAGCACCCGCCATGCGCGCTTTCCA
GTGATCGGTCAGTCCCTAGATGATGTCAGGGGTGTGCTTGATTTACGTCGGTTGGCGGAACCCATCTCCCGGGGTGCTTT
GCAGGCAGAATCTCCGCTTGAACCTTTTTTAGAACCAGCTGTAAGGGTTCTTGAGACCAGCACTTTGGCTGAATTGTTGC
CGATGATCCGAAGTGGACAGCCCCTACTGCTTGTCGTTGATGAGCATGGCGGTACAGAAGGATTGGTTACAGCTGCCGAT
CTCACTGGTGAGATCGTGGGCGATGAGCCCCATGCAGACGACGATGAGCCGGATCTTGAGCTGATTGAGGGTCAGTCAGA
CACATGGATGGTTGCAGGAGATCTTGAGATCATTGAGCTCAATCGACAGCTCAATCTGGACTTGCCTGAAGCTGATGGAC
ATCACACCTTGGCTGGCTTTCTGCTTGAAAAGTTGCAACACATCCCTTCTGCTGGAGAGGCCTTGCGCTGCGATGGTTTG
CAGTTCGAGATCGTAACGATGAAGGGTCCTCGTATCGAGCGTGTGCGACTGATTCTTCCCAGTCACGATCACACTGAGGA
ATGA

Upstream 100 bases:

>100_bases
ATCCGTGATTGAGGGGGTCTAGCAATCTGGTGAATGCAGCGAACTCATAATTCGCCTAAGGCGAGTTCGATCCTCGCGAC
CCCCATATTTTCTTCATTCA

Downstream 100 bases:

>100_bases
TCGTTGATAATTTCCCCGATGCGCCATGGCTTGCCGATGACCGATCCCATGGTTCCGGTGAAGGTCGGTGTGATCGGGAT
TGGCAATATGGGTTGGCATC

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MRLLFLAVLLVLPAFFAAGEVALLRLRPSRVQVLVEEQQPGASAVHRLQRRLRRALMVSQLGGMLALVALGWVGRGVGHR
WWPLADPASRWLDGGLFLLLVVLATLLAGFLPKAWVLNRPEASALNLAPLLEMVMRVLAPLLALLEAVASMMLRLVGLNA
HWDSLVPALSAGELESLIEIGGVTGLRPDERNILEGVFALRDTQVREVMVPRSGMVTLPVGVCFAELMRVVHSTRHARFP
VIGQSLDDVRGVLDLRRLAEPISRGALQAESPLEPFLEPAVRVLETSTLAELLPMIRSGQPLLLVVDEHGGTEGLVTAAD
LTGEIVGDEPHADDDEPDLELIEGQSDTWMVAGDLEIIELNRQLNLDLPEADGHHTLAGFLLEKLQHIPSAGEALRCDGL
QFEIVTMKGPRIERVRLILPSHDHTEE

Sequences:

>Translated_427_residues
MRLLFLAVLLVLPAFFAAGEVALLRLRPSRVQVLVEEQQPGASAVHRLQRRLRRALMVSQLGGMLALVALGWVGRGVGHR
WWPLADPASRWLDGGLFLLLVVLATLLAGFLPKAWVLNRPEASALNLAPLLEMVMRVLAPLLALLEAVASMMLRLVGLNA
HWDSLVPALSAGELESLIEIGGVTGLRPDERNILEGVFALRDTQVREVMVPRSGMVTLPVGVCFAELMRVVHSTRHARFP
VIGQSLDDVRGVLDLRRLAEPISRGALQAESPLEPFLEPAVRVLETSTLAELLPMIRSGQPLLLVVDEHGGTEGLVTAAD
LTGEIVGDEPHADDDEPDLELIEGQSDTWMVAGDLEIIELNRQLNLDLPEADGHHTLAGFLLEKLQHIPSAGEALRCDGL
QFEIVTMKGPRIERVRLILPSHDHTEE
>Mature_427_residues
MRLLFLAVLLVLPAFFAAGEVALLRLRPSRVQVLVEEQQPGASAVHRLQRRLRRALMVSQLGGMLALVALGWVGRGVGHR
WWPLADPASRWLDGGLFLLLVVLATLLAGFLPKAWVLNRPEASALNLAPLLEMVMRVLAPLLALLEAVASMMLRLVGLNA
HWDSLVPALSAGELESLIEIGGVTGLRPDERNILEGVFALRDTQVREVMVPRSGMVTLPVGVCFAELMRVVHSTRHARFP
VIGQSLDDVRGVLDLRRLAEPISRGALQAESPLEPFLEPAVRVLETSTLAELLPMIRSGQPLLLVVDEHGGTEGLVTAAD
LTGEIVGDEPHADDDEPDLELIEGQSDTWMVAGDLEIIELNRQLNLDLPEADGHHTLAGFLLEKLQHIPSAGEALRCDGL
QFEIVTMKGPRIERVRLILPSHDHTEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=389, Percent_Identity=24.6786632390745, Blast_Score=132, Evalue=7e-31,
Organism=Escherichia coli, GI145693175, Length=412, Percent_Identity=26.9417475728155, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790664, Length=429, Percent_Identity=24.009324009324, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786879, Length=251, Percent_Identity=32.2709163346614, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI87082033, Length=260, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788119, Length=242, Percent_Identity=27.6859504132231, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46687; Mature: 46687

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLFLAVLLVLPAFFAAGEVALLRLRPSRVQVLVEEQQPGASAVHRLQRRLRRALMVSQ
CHHHHHHHHHHHHHHHHCCCEEEEEECHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGGMLALVALGWVGRGVGHRWWPLADPASRWLDGGLFLLLVVLATLLAGFLPKAWVLNRP
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCC
EASALNLAPLLEMVMRVLAPLLALLEAVASMMLRLVGLNAHWDSLVPALSAGELESLIEI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
GGVTGLRPDERNILEGVFALRDTQVREVMVPRSGMVTLPVGVCFAELMRVVHSTRHARFP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCC
VIGQSLDDVRGVLDLRRLAEPISRGALQAESPLEPFLEPAVRVLETSTLAELLPMIRSGQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLLVVDEHGGTEGLVTAADLTGEIVGDEPHADDDEPDLELIEGQSDTWMVAGDLEIIEL
CEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCEEEEEE
NRQLNLDLPEADGHHTLAGFLLEKLQHIPSAGEALRCDGLQFEIVTMKGPRIERVRLILP
CCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEEECCCCEEEEEEEEC
SHDHTEE
CCCCCCC
>Mature Secondary Structure
MRLLFLAVLLVLPAFFAAGEVALLRLRPSRVQVLVEEQQPGASAVHRLQRRLRRALMVSQ
CHHHHHHHHHHHHHHHHCCCEEEEEECHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGGMLALVALGWVGRGVGHRWWPLADPASRWLDGGLFLLLVVLATLLAGFLPKAWVLNRP
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHCCCCC
EASALNLAPLLEMVMRVLAPLLALLEAVASMMLRLVGLNAHWDSLVPALSAGELESLIEI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHH
GGVTGLRPDERNILEGVFALRDTQVREVMVPRSGMVTLPVGVCFAELMRVVHSTRHARFP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCC
VIGQSLDDVRGVLDLRRLAEPISRGALQAESPLEPFLEPAVRVLETSTLAELLPMIRSGQ
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
PLLLVVDEHGGTEGLVTAADLTGEIVGDEPHADDDEPDLELIEGQSDTWMVAGDLEIIEL
CEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCEEEEEE
NRQLNLDLPEADGHHTLAGFLLEKLQHIPSAGEALRCDGLQFEIVTMKGPRIERVRLILP
CCEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEEEEEEECCCCEEEEEEEEC
SHDHTEE
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]