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The map label for this gene is cinA [C]

Identifier: 124024159

GI number: 124024159

Start: 2170890

End: 2172179

Strand: Reverse

Name: cinA [C]

Synonym: P9303_24701

Alternate gene names: 124024159

Gene position: 2172179-2170890 (Counterclockwise)

Preceding gene: 124024160

Following gene: 124024158

Centisome position: 80.97

GC content: 56.59

Gene sequence:

>1290_bases
GTGCCTATCGCGATGGTCATGGCTGAAGCTTCGGCTAGGCGTGGTGTTGAGATCCTTTGCATTGGCACGGAGCTGTTGCT
TGGCAACATCCTTAACAGCAATGCTCGTTGGTTAGCTGAGGAGCTGGCTGCTCTGGGGCTCCCTCATTACCGGCAAACTG
TTGTAGGAGACAACGTTGAACGTCTCAAAGAATCAGTTTTGGAGGCTGTTGATCGCAGTCGGATTCTGATCACCACTGGT
GGCCTAGGACCAACGCCTGATGATCTGACTACTGAAACTTTGGCGGCTGCTTTTGATACGCCGCTTGAGGAACGGCCAGA
ACTTTGGCTCGAGATTCAGGCCAAGCTCACTGCTGGCGGCAGCATTTCTGCAATCAGCAATCGCAAACAGGCGTTGTTCC
CTCGTGGAGCTGAAATCCTTCCAAATCCCTCCGGCACTGCGCCGGGGATGATCTGGTGTCCTCGGCCGGGGTTCACTGTG
ATCACCTTTCCGGGTGTGCCTTCTGAAATGAAGCAGATGTGGTCCCAGACAGCCGTGCCATGGCTGCGTCAGCACGGAGG
AGTGGCTGACATCTTTGTGAGTCGGCTGTTGCGGTTTACAGGCATTGCTGAATCCACGCTGGCTGAAGAGGTGTCTGATT
TGCTTGAGCAGAGCAATCCAACAGTGGCCCCTTATGCCGGACTGGGAGAGGTAAAACTACGGATCACGGCCCGGGGGGCA
ACGGTGGAGCAAGCGAGGCAGCTATTGGATCCAGTGGATGCAGAGCTCCGTCATCGCACCGGCTTGTTCTGTTACGGCTC
GGATGATGAGAGCTTGGCATCGGTTGTGCTGGATTTGTTGCGTCAACGAGGTGAGACCGTTGTAGTGGCAGAGTCCTGTA
CAGGTGGCGGAGTTGGTGCCGCTTTGGCTGCTGTTCCGAGAGCTTCTGAGGTTCTTCTAGGCGGGGTTATTGCTTACAGC
AATGCCATTAAGCAAGCCCTACTGGGTATATCCACAGACCTTTTGCACCAGCACGGTGCAGTTTCGGATCCTGTGGTGCG
GGCTATGGCTGAAGGGGCGCGTCAACGGCTCGGGGCAGATTGGTCTATTGCGGTGAGCGGTGTGGCAGGCCCTGGCGGTG
GTACGCAGGCCAAGCCTGTGGGGTTAGTGCATATCGCAGTGGCTGGACCGCATGGCTGTCAGGCAAGCCCTGTGCAGTTC
GGTGTTCGTCGTGGAAGGTTGGCAATTCAGGAGCTGAGTGTGGTTCGCAGTCTCGATCTGCTGCGCAGGTTCCTGCTGGA
TGGGAGCTAA

Upstream 100 bases:

>100_bases
GCCATTCTCGTGGCGACAGTCGTGATCAGCCGTCGTCAACGTAGTGCTGAAGGTGCCTTCGTAGACCCTTCTAGCTCCCT
TGCAGCTCCTAGTGATCCAC

Downstream 100 bases:

>100_bases
GGTTTTCGGCTACTGCCTCTGAACCTTGAGCTCCGGCACCCTCTACGACAAGGTGTGGGATCTACATCGGGTGGCTGACC
TACCTGGTGGATCCACTCAG

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MPIAMVMAEASARRGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVERLKESVLEAVDRSRILITTG
GLGPTPDDLTTETLAAAFDTPLEERPELWLEIQAKLTAGGSISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTV
ITFPGVPSEMKQMWSQTAVPWLRQHGGVADIFVSRLLRFTGIAESTLAEEVSDLLEQSNPTVAPYAGLGEVKLRITARGA
TVEQARQLLDPVDAELRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGAALAAVPRASEVLLGGVIAYS
NAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGADWSIAVSGVAGPGGGTQAKPVGLVHIAVAGPHGCQASPVQF
GVRRGRLAIQELSVVRSLDLLRRFLLDGS

Sequences:

>Translated_429_residues
MPIAMVMAEASARRGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVERLKESVLEAVDRSRILITTG
GLGPTPDDLTTETLAAAFDTPLEERPELWLEIQAKLTAGGSISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTV
ITFPGVPSEMKQMWSQTAVPWLRQHGGVADIFVSRLLRFTGIAESTLAEEVSDLLEQSNPTVAPYAGLGEVKLRITARGA
TVEQARQLLDPVDAELRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGAALAAVPRASEVLLGGVIAYS
NAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGADWSIAVSGVAGPGGGTQAKPVGLVHIAVAGPHGCQASPVQF
GVRRGRLAIQELSVVRSLDLLRRFLLDGS
>Mature_428_residues
PIAMVMAEASARRGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVERLKESVLEAVDRSRILITTGG
LGPTPDDLTTETLAAAFDTPLEERPELWLEIQAKLTAGGSISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTVI
TFPGVPSEMKQMWSQTAVPWLRQHGGVADIFVSRLLRFTGIAESTLAEEVSDLLEQSNPTVAPYAGLGEVKLRITARGAT
VEQARQLLDPVDAELRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGAALAAVPRASEVLLGGVIAYSN
AIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGADWSIAVSGVAGPGGGTQAKPVGLVHIAVAGPHGCQASPVQFG
VRRGRLAIQELSVVRSLDLLRRFLLDGS

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family [H]

Homologues:

Organism=Escherichia coli, GI1788583, Length=412, Percent_Identity=30.3398058252427, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1789052, Length=121, Percent_Identity=43.801652892562, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787818, Length=112, Percent_Identity=36.6071428571429, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453 [H]

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 45367; Mature: 45235

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00511 CRF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAMVMAEASARRGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVE
CCCEEEEEHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHH
RLKESVLEAVDRSRILITTGGLGPTPDDLTTETLAAAFDTPLEERPELWLEIQAKLTAGG
HHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCC
SISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTVITFPGVPSEMKQMWSQTAVP
CCHHHCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCH
WLRQHGGVADIFVSRLLRFTGIAESTLAEEVSDLLEQSNPTVAPYAGLGEVKLRITARGA
HHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCC
TVEQARQLLDPVDAELRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGA
CHHHHHHHHCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALAAVPRASEVLLGGVIAYSNAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGAD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
WSIAVSGVAGPGGGTQAKPVGLVHIAVAGPHGCQASPVQFGVRRGRLAIQELSVVRSLDL
CEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRFLLDGS
HHHHHCCCC
>Mature Secondary Structure 
PIAMVMAEASARRGVEILCIGTELLLGNILNSNARWLAEELAALGLPHYRQTVVGDNVE
CCEEEEEHHHHHCCCEEEEECHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHCCCHH
RLKESVLEAVDRSRILITTGGLGPTPDDLTTETLAAAFDTPLEERPELWLEIQAKLTAGG
HHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCC
SISAISNRKQALFPRGAEILPNPSGTAPGMIWCPRPGFTVITFPGVPSEMKQMWSQTAVP
CCHHHCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCH
WLRQHGGVADIFVSRLLRFTGIAESTLAEEVSDLLEQSNPTVAPYAGLGEVKLRITARGA
HHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCC
TVEQARQLLDPVDAELRHRTGLFCYGSDDESLASVVLDLLRQRGETVVVAESCTGGGVGA
CHHHHHHHHCHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCHHH
ALAAVPRASEVLLGGVIAYSNAIKQALLGISTDLLHQHGAVSDPVVRAMAEGARQRLGAD
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
WSIAVSGVAGPGGGTQAKPVGLVHIAVAGPHGCQASPVQFGVRRGRLAIQELSVVRSLDL
CEEEEECCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LRRFLLDGS
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]