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The map label for this gene is mpg

Identifier: 124024109

GI number: 124024109

Start: 2129059

End: 2129736

Strand: Reverse

Name: mpg

Synonym: P9303_24181

Alternate gene names: NA

Gene position: 2129736-2129059 (Counterclockwise)

Preceding gene: 124024110

Following gene: 124024107

Centisome position: 79.39

GC content: 57.52

Gene sequence:

>678_bases
ATGGAGGCACTACCGCTGAGTTTCTTCTGCCGCCCTGCCGAGGTAGTGGGACCAGAGTTGGTGGGTTGCAGGTTGGTGAA
ACGCCAGAGCGATGGAAGCCTGCTTTGGGGCGTGATTGTGGAAACGGAGGCGTATTCGCAGGATGAGCCTGCTTGTCACG
GCTATCGGCGCCGCTCACCGCAAAACGAAACGCTGTTTGGCGAGCCAGGGCGGTTTTATGTGTATGTGAGCTATGGCATT
CACCATTGCGTCAATGTGGTCACCGATCGCGCTGAATGGGCGAATGGTGTTTTGTTGAGGGCGATTGCACTGCCGGACGA
ACTGGAACGCGTCGCGGCGGGGCCAGCTTTATTGGCGCGTCGTTTTGGTCTGGACCGCTCCCATGACAGAACTGCCGTCA
CAGGAGAGAATGATGTGTGGCTGGCACCTAGGCCGGCTGCTTTCGGTACGCCAACGATTGTGAGCACAACCAGGATCGGT
ATCTCTCAAGGACAAGATCTTCCTTGGCGTTGGTATCTGAAGAACTGTCGCAGCATTAGTCGCCGTGCCAAGGGAGATCG
CACGCCGCCTTTGCAACAAGCCTGGGCTCCTGTTGCTAGTGGATGGCCCATGAGCGGCTGGTCCCATCGGCATATCCTTG
ATCTGGCCAGCTACGCAGTGCTAGGCGAATGGAGTTGA

Upstream 100 bases:

>100_bases
TAAAATTGAAAAGGGTAGGCAAAAAGATGATGTCAATCCCTATTGGACTGCTGCCTAGGGTGTCTATGCCTAAGCCAGAA
AGCAAGCCAGTTTGGGAGTT

Downstream 100 bases:

>100_bases
CGCTGCTGACGGCGCCGGACAGGGTGGAGGACTTGATGGGGAGGTGAGTCTGTATGAATGCTCAATAGGAGAGATAATCT
CTTCCTGATTATCAATGTGG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MEALPLSFFCRPAEVVGPELVGCRLVKRQSDGSLLWGVIVETEAYSQDEPACHGYRRRSPQNETLFGEPGRFYVYVSYGI
HHCVNVVTDRAEWANGVLLRAIALPDELERVAAGPALLARRFGLDRSHDRTAVTGENDVWLAPRPAAFGTPTIVSTTRIG
ISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASGWPMSGWSHRHILDLASYAVLGEWS

Sequences:

>Translated_225_residues
MEALPLSFFCRPAEVVGPELVGCRLVKRQSDGSLLWGVIVETEAYSQDEPACHGYRRRSPQNETLFGEPGRFYVYVSYGI
HHCVNVVTDRAEWANGVLLRAIALPDELERVAAGPALLARRFGLDRSHDRTAVTGENDVWLAPRPAAFGTPTIVSTTRIG
ISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASGWPMSGWSHRHILDLASYAVLGEWS
>Mature_225_residues
MEALPLSFFCRPAEVVGPELVGCRLVKRQSDGSLLWGVIVETEAYSQDEPACHGYRRRSPQNETLFGEPGRFYVYVSYGI
HHCVNVVTDRAEWANGVLLRAIALPDELERVAAGPALLARRFGLDRSHDRTAVTGENDVWLAPRPAAFGTPTIVSTTRIG
ISQGQDLPWRWYLKNCRSISRRAKGDRTPPLQQAWAPVASGWPMSGWSHRHILDLASYAVLGEWS

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=163, Percent_Identity=31.9018404907975, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI62632771, Length=163, Percent_Identity=31.9018404907975, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI62632765, Length=163, Percent_Identity=31.9018404907975, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 25110; Mature: 25110

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALPLSFFCRPAEVVGPELVGCRLVKRQSDGSLLWGVIVETEAYSQDEPACHGYRRRSP
CCCCCCHHCCCCHHHCCCHHHHEEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHCCC
QNETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDELERVAAGPALLAR
CCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCHHHHHH
RFGLDRSHDRTAVTGENDVWLAPRPAAFGTPTIVSTTRIGISQGQDLPWRWYLKNCRSIS
HHCCCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
RRAKGDRTPPLQQAWAPVASGWPMSGWSHRHILDLASYAVLGEWS
HHHCCCCCCCHHHHHCHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEALPLSFFCRPAEVVGPELVGCRLVKRQSDGSLLWGVIVETEAYSQDEPACHGYRRRSP
CCCCCCHHCCCCHHHCCCHHHHEEEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHCCC
QNETLFGEPGRFYVYVSYGIHHCVNVVTDRAEWANGVLLRAIALPDELERVAAGPALLAR
CCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHCCHHHHHH
RFGLDRSHDRTAVTGENDVWLAPRPAAFGTPTIVSTTRIGISQGQDLPWRWYLKNCRSIS
HHCCCCCCCCEEEECCCCEEECCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHH
RRAKGDRTPPLQQAWAPVASGWPMSGWSHRHILDLASYAVLGEWS
HHHCCCCCCCHHHHHCHHCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA