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The map label for this gene is mtnB [H]

Identifier: 124023870

GI number: 124023870

Start: 1933333

End: 1933956

Strand: Direct

Name: mtnB [H]

Synonym: P9303_21771

Alternate gene names: 124023870

Gene position: 1933333-1933956 (Clockwise)

Preceding gene: 124023869

Following gene: 124023871

Centisome position: 72.07

GC content: 45.83

Gene sequence:

>624_bases
ATGTTCGATTCACAGCAACAGCGGCAAGCTCTAAGCAACACCATTCGCGATTTCCATCAACGCGGTTGGTGTGATGGAAC
TGGCGGTAATTTCAGCCTAGTGCTACAAAAAACGCCATTGAGATTATTGATGGCACCTAGCGGCATTGAGAAAAGAAATA
TCGAGGCAGACGAACTCATTGAAGTCGACAGCTCAGGCAACGTGATTCAAGGAGAAGGTAGAGCAAGTGCTGAAACAGAT
ATGCATTTAAAAATCATCGAGCAGACCAACGCCAAGGCCGTACTGCACACACACTCAATGACAGCAACATGGCTATCGAA
CTACTATAAAAATACTGGGAAAATAACAATTGAGGGCTGGGAAATGCTGAAAGGGCTGAAAGGGATTAACAGCCATTACA
CATCAATCACTCTGCCAATCCTATTGAACAACCAAAACCTAGCCAAATTAAGCCAAGCAGCAGGCAAACTGGTCAATGAT
GCACCCTATGGACTACTGGTCGCAGGGCACGGTTTATACGCTTGGGGGGAGAGCCTAAACGAAGCAAGACGTCATGTAGA
AATCTTGGAGTTCCTACTAGAGCTCTGCTGGCGTGAACAACTTATAGCCAGACAAAAATCGTGA

Upstream 100 bases:

>100_bases
CCAAGCCTGCCGGATATGCAGCACGCCAATCCGCCGTGAAAGCCTCTGCGGTCGTGGCACCCACTGGTGCCCCAATTGCC
AAAGATGAATCCTGGCAAAA

Downstream 100 bases:

>100_bases
TCACTCACATCTTGCTGGATATTGAGGGCACCACATGCCCCACAAGTTTTGTCAGCGACACTCTCTATCCTTACGCGTAT
AGCCATCTAGAAGGATTTCT

Product: sugar aldolase

Products: NA

Alternate protein names: MTRu-1-P dehydratase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFDSQQQRQALSNTIRDFHQRGWCDGTGGNFSLVLQKTPLRLLMAPSGIEKRNIEADELIEVDSSGNVIQGEGRASAETD
MHLKIIEQTNAKAVLHTHSMTATWLSNYYKNTGKITIEGWEMLKGLKGINSHYTSITLPILLNNQNLAKLSQAAGKLVND
APYGLLVAGHGLYAWGESLNEARRHVEILEFLLELCWREQLIARQKS

Sequences:

>Translated_207_residues
MFDSQQQRQALSNTIRDFHQRGWCDGTGGNFSLVLQKTPLRLLMAPSGIEKRNIEADELIEVDSSGNVIQGEGRASAETD
MHLKIIEQTNAKAVLHTHSMTATWLSNYYKNTGKITIEGWEMLKGLKGINSHYTSITLPILLNNQNLAKLSQAAGKLVND
APYGLLVAGHGLYAWGESLNEARRHVEILEFLLELCWREQLIARQKS
>Mature_207_residues
MFDSQQQRQALSNTIRDFHQRGWCDGTGGNFSLVLQKTPLRLLMAPSGIEKRNIEADELIEVDSSGNVIQGEGRASAETD
MHLKIIEQTNAKAVLHTHSMTATWLSNYYKNTGKITIEGWEMLKGLKGINSHYTSITLPILLNNQNLAKLSQAAGKLVND
APYGLLVAGHGLYAWGESLNEARRHVEILEFLLELCWREQLIARQKS

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily [H]

Homologues:

Organism=Homo sapiens, GI166235186, Length=205, Percent_Identity=27.3170731707317, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322484, Length=209, Percent_Identity=24.8803827751196, Blast_Score=73, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859685, Length=209, Percent_Identity=24.8803827751196, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR017714 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.2.1.109 [H]

Molecular weight: Translated: 23173; Mature: 23173

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSQQQRQALSNTIRDFHQRGWCDGTGGNFSLVLQKTPLRLLMAPSGIEKRNIEADELI
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCHHHEE
EVDSSGNVIQGEGRASAETDMHLKIIEQTNAKAVLHTHSMTATWLSNYYKNTGKITIEGW
EECCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCEEEEEHH
EMLKGLKGINSHYTSITLPILLNNQNLAKLSQAAGKLVNDAPYGLLVAGHGLYAWGESLN
HHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
EARRHVEILEFLLELCWREQLIARQKS
HHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFDSQQQRQALSNTIRDFHQRGWCDGTGGNFSLVLQKTPLRLLMAPSGIEKRNIEADELI
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCHHHEE
EVDSSGNVIQGEGRASAETDMHLKIIEQTNAKAVLHTHSMTATWLSNYYKNTGKITIEGW
EECCCCCEEECCCCCCCCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHCCCCEEEEEHH
EMLKGLKGINSHYTSITLPILLNNQNLAKLSQAAGKLVNDAPYGLLVAGHGLYAWGESLN
HHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
EARRHVEILEFLLELCWREQLIARQKS
HHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA