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The map label for this gene is cobI [H]

Identifier: 124023852

GI number: 124023852

Start: 1918286

End: 1919050

Strand: Reverse

Name: cobI [H]

Synonym: P9303_21591

Alternate gene names: 124023852

Gene position: 1919050-1918286 (Counterclockwise)

Preceding gene: 124023854

Following gene: 124023851

Centisome position: 71.53

GC content: 59.48

Gene sequence:

>765_bases
ATGTTTCGTTCGGCTTTGTCGAGCCCTGCTGTTTCAACTACAGCTCTCATCCTGGTCGGGGTGGGCCCTGGTGATCCTGC
CCTGTTGACCCTGGCTGCCATTGAGGCGATTGAAGCGGCCACTGTTGTGGCCTATCCCGTGGCACGGCTAGGGGGTGAAG
GGATGGCGGCGAGCATTGCCTCGCGATGGATTCGTGCTGAGCAACGCCAACTGCCATTGCTTTTTCCCATGGTGGCTGCC
GTTGAACCGCGCCAGCAGGCTTGGCGAGAGGCCAGTGATCAACTGGCAACTGCCGTTGCTGAAGGAGAGCGAGTGGTGGT
GCTTTGTCAGGGGGATGTTTCCCTGTTTGCCACAAGCTCTTACATCTTGCTGGCTCTCAAAAAGCATCATCCTGATTGCC
AGGTTCGGCTGATCCCAGGGGTCACGGCCGTTGCAGCCGCCGCGGCTGCAGGTAAGTGGCCCTTGGCGATGCAGCAGGAA
CAACTTTTGCTTTTGCCGACCCCAGATCAATCCAGCGAGCTCGAGGTTCTACTAGAGGATGCGGCTGGTTCTGGGCGTGT
GCTGGCGTTGCTGAAGTTGGCGCACCGCTGGGCCTGGGTGCGGCCCATGCTCGAAGAGCGGAATTTATTGCAATCAGCAC
TCTTTGCCCAGAGGTTGGGCTGGCCTGATCAGCAGGTGATGCAGGCCTGCGAGGTGCCCGCAACAGCTAGGCCCTATTTT
TCGTTGTTGTTGGTGCGGCAAGGCTGGCCGGAGGTGATGCCCTGA

Upstream 100 bases:

>100_bases
TTGGTGTTGCCTTCGGGGTGGATGCTGAGGCGACTCATTCCCAGAGGTTGAAGGGGTCTTTGCAGCCATCTTGATCGTGG
CGTCTTAGAACGACGGCTGA

Downstream 100 bases:

>100_bases
TGTCTAGTGCTCTCTCTTTGACCGCCATGCAGTGGCTTGGCTTGTTGCACCCCGTGTTGATCATTTTGTTTGTTTATCCA
GTGGTGGGTGCCACGATTCG

Product: precorrin-2 C20-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MFRSALSSPAVSTTALILVGVGPGDPALLTLAAIEAIEAATVVAYPVARLGGEGMAASIASRWIRAEQRQLPLLFPMVAA
VEPRQQAWREASDQLATAVAEGERVVVLCQGDVSLFATSSYILLALKKHHPDCQVRLIPGVTAVAAAAAAGKWPLAMQQE
QLLLLPTPDQSSELEVLLEDAAGSGRVLALLKLAHRWAWVRPMLEERNLLQSALFAQRLGWPDQQVMQACEVPATARPYF
SLLLVRQGWPEVMP

Sequences:

>Translated_254_residues
MFRSALSSPAVSTTALILVGVGPGDPALLTLAAIEAIEAATVVAYPVARLGGEGMAASIASRWIRAEQRQLPLLFPMVAA
VEPRQQAWREASDQLATAVAEGERVVVLCQGDVSLFATSSYILLALKKHHPDCQVRLIPGVTAVAAAAAAGKWPLAMQQE
QLLLLPTPDQSSELEVLLEDAAGSGRVLALLKLAHRWAWVRPMLEERNLLQSALFAQRLGWPDQQVMQACEVPATARPYF
SLLLVRQGWPEVMP
>Mature_254_residues
MFRSALSSPAVSTTALILVGVGPGDPALLTLAAIEAIEAATVVAYPVARLGGEGMAASIASRWIRAEQRQLPLLFPMVAA
VEPRQQAWREASDQLATAVAEGERVVVLCQGDVSLFATSSYILLALKKHHPDCQVRLIPGVTAVAAAAAAGKWPLAMQQE
QLLLLPTPDQSSELEVLLEDAAGSGRVLALLKLAHRWAWVRPMLEERNLLQSALFAQRLGWPDQQVMQACEVPATARPYF
SLLLVRQGWPEVMP

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 27369; Mature: 27369

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSALSSPAVSTTALILVGVGPGDPALLTLAAIEAIEAATVVAYPVARLGGEGMAASIA
CCCHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SRWIRAEQRQLPLLFPMVAAVEPRQQAWREASDQLATAVAEGERVVVLCQGDVSLFATSS
HHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEECCC
YILLALKKHHPDCQVRLIPGVTAVAAAAAAGKWPLAMQQEQLLLLPTPDQSSELEVLLED
EEEEEEECCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHEEEC
AAGSGRVLALLKLAHRWAWVRPMLEERNLLQSALFAQRLGWPDQQVMQACEVPATARPYF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
SLLLVRQGWPEVMP
HHHHHHCCCCCCCC
>Mature Secondary Structure
MFRSALSSPAVSTTALILVGVGPGDPALLTLAAIEAIEAATVVAYPVARLGGEGMAASIA
CCCHHHCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SRWIRAEQRQLPLLFPMVAAVEPRQQAWREASDQLATAVAEGERVVVLCQGDVSLFATSS
HHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEECCC
YILLALKKHHPDCQVRLIPGVTAVAAAAAAGKWPLAMQQEQLLLLPTPDQSSELEVLLED
EEEEEEECCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHEEEC
AAGSGRVLALLKLAHRWAWVRPMLEERNLLQSALFAQRLGWPDQQVMQACEVPATARPYF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
SLLLVRQGWPEVMP
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]