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The map label for this gene is era [H]

Identifier: 124023647

GI number: 124023647

Start: 1712064

End: 1713095

Strand: Reverse

Name: era [H]

Synonym: P9303_19471

Alternate gene names: 124023647

Gene position: 1713095-1712064 (Counterclockwise)

Preceding gene: 124023649

Following gene: 124023646

Centisome position: 63.86

GC content: 56.69

Gene sequence:

>1032_bases
TTGTTCAAAGCTTGGCGCTGGGGTGCTCATGGATGTTATGCATGCTTTCAGTCAGGCTATGGGGCCACATTGAGCCAGGT
CATGTCGCCTGAGGCTATGGAGTCTCTCCCTGAGGGATATCGTTCCGGTTTTGTCGCTTTAATTGGCAGGCCCAATGTGG
GCAAATCCACCTTGGTGAATCAGTTGGTGGGAGAGAAGGTGGCGATTACTTCTCCTGTGGCGCAGACCACGCGCAATCGG
CTGCGGGCCATCGTCACCACCCCCGAGGCTCAGATGGTGCTAGTGGACACCCCTGGGATTCACAAACCTCACCATCTGCT
TGGTGAACGGCTGGTGCAAAGCGCCCGTGCAGCCATTGGTGAGGTTGACCTGGTGTTGCTTCTGCTTGAGGGCTGTGAAC
CACCCGGCCGTGGTGATGCTTTTATCGTGGAACTGCTACGCCAGCAGGATCTGCCGGTGTTAGTTGCTCTTAATAAGTGG
GATCGTGTTGCTGAGCAGCAACACGATCCGGCTGAGGAGGCTTATCGGCAGCTGTTGGCAGACTCTGCTTGGCCGCTCAT
ACGTTGCAGTGCGATTAGTGGTGAGGGATGCAATGGGCTTGTAGAAGCTTTAGTGGGGCAGCTGCCACTAGGCCCCCAGC
TCTATCCAGCTGAGATGGTGTGTGATCAGCCGGAGCGGGTGCTGCTGGCTGAACTGATTCGCGAGCAGGTGCTGATGCAT
ACCCGTGAGGAGGTGCCCCATAGCGTGGCGGTGAGCATTGATCGGGTTGAAGAGATGCCTGTTGCCAATGGACGTCCTGG
CAAACAGGGGAGGACGGCTGTGTTGGCCACAGTGCTGGTGGAACGCAAGAGCCAGAAGGGGATCCTGATCGGCAAGGGAG
GCTCGATGTTGAAGACGATTGGTCAGGGAGCGCGCTTGCAGATGCAGACCTTGATCGATGGTCCTGTTTACCTAGAATTA
TTTGTGAAGGTGGTGCCTGATTGGCGCTCTAAGCCAGCGCGATTGGCGGAGCTTGGTTTTGAGGGCAAGTGA

Upstream 100 bases:

>100_bases
CACGACTGGCCACCAATTCCGAGACCCGGTCGGCGAGGACTTCATCACTGAGTTCGCCCTCTTCCCATAACCTCAGCCAC
TGAGCGGTGATTTCAATCGC

Downstream 100 bases:

>100_bases
TTATTGCCCGTTTCAAATGGGCGACTGAGAGGATTGATGAATGATTGATGTTCCAAACCCTTTTTTAAAGTCTTTTCGGC
TGAGGTTATTTCTTCAGGGG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MFKAWRWGAHGCYACFQSGYGATLSQVMSPEAMESLPEGYRSGFVALIGRPNVGKSTLVNQLVGEKVAITSPVAQTTRNR
LRAIVTTPEAQMVLVDTPGIHKPHHLLGERLVQSARAAIGEVDLVLLLLEGCEPPGRGDAFIVELLRQQDLPVLVALNKW
DRVAEQQHDPAEEAYRQLLADSAWPLIRCSAISGEGCNGLVEALVGQLPLGPQLYPAEMVCDQPERVLLAELIREQVLMH
TREEVPHSVAVSIDRVEEMPVANGRPGKQGRTAVLATVLVERKSQKGILIGKGGSMLKTIGQGARLQMQTLIDGPVYLEL
FVKVVPDWRSKPARLAELGFEGK

Sequences:

>Translated_343_residues
MFKAWRWGAHGCYACFQSGYGATLSQVMSPEAMESLPEGYRSGFVALIGRPNVGKSTLVNQLVGEKVAITSPVAQTTRNR
LRAIVTTPEAQMVLVDTPGIHKPHHLLGERLVQSARAAIGEVDLVLLLLEGCEPPGRGDAFIVELLRQQDLPVLVALNKW
DRVAEQQHDPAEEAYRQLLADSAWPLIRCSAISGEGCNGLVEALVGQLPLGPQLYPAEMVCDQPERVLLAELIREQVLMH
TREEVPHSVAVSIDRVEEMPVANGRPGKQGRTAVLATVLVERKSQKGILIGKGGSMLKTIGQGARLQMQTLIDGPVYLEL
FVKVVPDWRSKPARLAELGFEGK
>Mature_343_residues
MFKAWRWGAHGCYACFQSGYGATLSQVMSPEAMESLPEGYRSGFVALIGRPNVGKSTLVNQLVGEKVAITSPVAQTTRNR
LRAIVTTPEAQMVLVDTPGIHKPHHLLGERLVQSARAAIGEVDLVLLLLEGCEPPGRGDAFIVELLRQQDLPVLVALNKW
DRVAEQQHDPAEEAYRQLLADSAWPLIRCSAISGEGCNGLVEALVGQLPLGPQLYPAEMVCDQPERVLLAELIREQVLMH
TREEVPHSVAVSIDRVEEMPVANGRPGKQGRTAVLATVLVERKSQKGILIGKGGSMLKTIGQGARLQMQTLIDGPVYLEL
FVKVVPDWRSKPARLAELGFEGK

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=310, Percent_Identity=36.7741935483871, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI87082120, Length=181, Percent_Identity=29.8342541436464, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646434, Length=251, Percent_Identity=28.2868525896414, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 37410; Mature: 37410

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKAWRWGAHGCYACFQSGYGATLSQVMSPEAMESLPEGYRSGFVALIGRPNVGKSTLVN
CCCCCCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
QLVGEKVAITSPVAQTTRNRLRAIVTTPEAQMVLVDTPGIHKPHHLLGERLVQSARAAIG
HHHCCCEEECCHHHHHHHHHHEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EVDLVLLLLEGCEPPGRGDAFIVELLRQQDLPVLVALNKWDRVAEQQHDPAEEAYRQLLA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHH
DSAWPLIRCSAISGEGCNGLVEALVGQLPLGPQLYPAEMVCDQPERVLLAELIREQVLMH
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
TREEVPHSVAVSIDRVEEMPVANGRPGKQGRTAVLATVLVERKSQKGILIGKGGSMLKTI
HHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHH
GQGARLQMQTLIDGPVYLELFVKVVPDWRSKPARLAELGFEGK
CCCCCEEEHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCC
>Mature Secondary Structure
MFKAWRWGAHGCYACFQSGYGATLSQVMSPEAMESLPEGYRSGFVALIGRPNVGKSTLVN
CCCCCCCCCHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHH
QLVGEKVAITSPVAQTTRNRLRAIVTTPEAQMVLVDTPGIHKPHHLLGERLVQSARAAIG
HHHCCCEEECCHHHHHHHHHHEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHH
EVDLVLLLLEGCEPPGRGDAFIVELLRQQDLPVLVALNKWDRVAEQQHDPAEEAYRQLLA
HHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHH
DSAWPLIRCSAISGEGCNGLVEALVGQLPLGPQLYPAEMVCDQPERVLLAELIREQVLMH
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
TREEVPHSVAVSIDRVEEMPVANGRPGKQGRTAVLATVLVERKSQKGILIGKGGSMLKTI
HHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHH
GQGARLQMQTLIDGPVYLELFVKVVPDWRSKPARLAELGFEGK
CCCCCEEEHHHHCCHHHHHHHHHHCCCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA