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The map label for this gene is surE

Identifier: 124023635

GI number: 124023635

Start: 1704236

End: 1705045

Strand: Direct

Name: surE

Synonym: P9303_19351

Alternate gene names: 124023635

Gene position: 1704236-1705045 (Clockwise)

Preceding gene: 124023631

Following gene: 124023637

Centisome position: 63.53

GC content: 57.9

Gene sequence:

>810_bases
ATGACTCCGTTGCGAATTCTGATTAGCAATGATGACGGAGTTTTAGCTGAAGGCGTCCGCTGCCTAGCCGCTGCCGCCGC
CAGCCGCGGCCATAAGGTCACAGTGGTCTGTCCCGACCATGAGCGCTCTGCTACCGGCCATGGCCTCACCATCCATACCC
CCATCCGAGCCGAACGCGTCGATGAGCTCTACGGGCCAGGTGTGACGGCTTGGTCCTGCAGTGGCACGCCGGCAGATTGC
GTCAAACTGGCCCTATCGGAACTCTTGGCAGAGAAGCCCGATCTAGTGCTCTCTGGGGTCAACCATGGCCCCAACTTAGG
AACTGATGTGTTCTGTTCAGGCACGGTGGCCGCAGCAATGGAAGGCACCCTTGAGGGATTGCCCGCGCTTGCGGTCAGCG
TCGCCTGCTTCCAATGGAGGGATTTCCAGGCTGCTGCCGAGTTAGCGATGGATGTTGCAGAGAATGCATTGGCAGACAAC
TGGCCCAACAACCTGCTGCTTAATCTCAACATTCCCCCCTGCCATCCAGAGCAGATGGGATCACTGCGCTGGACTCGCCT
TTCAATACGCCACTACGAGGAACAGTTCAGTCGACGTGTCGATCCGCACAGCCGCACCTACTTCTGGTTAGCAGGAGAAG
TGGTGAAAGATCTTGAGACCGCCGGCGATGGTCCACGCGACTGGCCCAGCGACGTGGCCCAAATCGAAACAAATTCCCCC
TCCTTGACACCCATCCAACCCGATCTGTTTTGGCGTGGTGATCTTTCTGCTCTACCAGCAGCATGCGTAGCCAATCAACC
AGTGCGATAA

Upstream 100 bases:

>100_bases
AGTGGCGCTCACTGAAAAAAGATCGCAGCCACTGACTTTAGGCAGTCATCATGCTTTAGGCAGTCATCATGATTAAGTTC
CCCGCAGTGGATACAAGGAG

Downstream 100 bases:

>100_bases
ATCCTCTGCAACAACCAAAGCGAAAAGATCAGACCAACCAAATGCGCAAATAACACCTGGGTGTTGCTCAGAACTGAAAG
CATCTCCAAGGAGGTGATCG

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTPLRILISNDDGVLAEGVRCLAAAAASRGHKVTVVCPDHERSATGHGLTIHTPIRAERVDELYGPGVTAWSCSGTPADC
VKLALSELLAEKPDLVLSGVNHGPNLGTDVFCSGTVAAAMEGTLEGLPALAVSVACFQWRDFQAAAELAMDVAENALADN
WPNNLLLNLNIPPCHPEQMGSLRWTRLSIRHYEEQFSRRVDPHSRTYFWLAGEVVKDLETAGDGPRDWPSDVAQIETNSP
SLTPIQPDLFWRGDLSALPAACVANQPVR

Sequences:

>Translated_269_residues
MTPLRILISNDDGVLAEGVRCLAAAAASRGHKVTVVCPDHERSATGHGLTIHTPIRAERVDELYGPGVTAWSCSGTPADC
VKLALSELLAEKPDLVLSGVNHGPNLGTDVFCSGTVAAAMEGTLEGLPALAVSVACFQWRDFQAAAELAMDVAENALADN
WPNNLLLNLNIPPCHPEQMGSLRWTRLSIRHYEEQFSRRVDPHSRTYFWLAGEVVKDLETAGDGPRDWPSDVAQIETNSP
SLTPIQPDLFWRGDLSALPAACVANQPVR
>Mature_268_residues
TPLRILISNDDGVLAEGVRCLAAAAASRGHKVTVVCPDHERSATGHGLTIHTPIRAERVDELYGPGVTAWSCSGTPADCV
KLALSELLAEKPDLVLSGVNHGPNLGTDVFCSGTVAAAMEGTLEGLPALAVSVACFQWRDFQAAAELAMDVAENALADNW
PNNLLLNLNIPPCHPEQMGSLRWTRLSIRHYEEQFSRRVDPHSRTYFWLAGEVVKDLETAGDGPRDWPSDVAQIETNSPS
LTPIQPDLFWRGDLSALPAACVANQPVR

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=246, Percent_Identity=37.3983739837398, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_PROM3 (A2CB17)

Other databases:

- EMBL:   CP000554
- RefSeq:   YP_001017942.1
- ProteinModelPortal:   A2CB17
- SMR:   A2CB17
- STRING:   A2CB17
- GeneID:   4777385
- GenomeReviews:   CP000554_GR
- KEGG:   pmf:P9303_19351
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 29007; Mature: 28876

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLRILISNDDGVLAEGVRCLAAAAASRGHKVTVVCPDHERSATGHGLTIHTPIRAERV
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
DELYGPGVTAWSCSGTPADCVKLALSELLAEKPDLVLSGVNHGPNLGTDVFCSGTVAAAM
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEECCHHHHHH
EGTLEGLPALAVSVACFQWRDFQAAAELAMDVAENALADNWPNNLLLNLNIPPCHPEQMG
HHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHC
SLRWTRLSIRHYEEQFSRRVDPHSRTYFWLAGEVVKDLETAGDGPRDWPSDVAQIETNSP
CEEEEHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHEEECCCC
SLTPIQPDLFWRGDLSALPAACVANQPVR
CCCCCCCCCEECCCCHHCCHHHHCCCCCC
>Mature Secondary Structure 
TPLRILISNDDGVLAEGVRCLAAAAASRGHKVTVVCPDHERSATGHGLTIHTPIRAERV
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCHHHHHH
DELYGPGVTAWSCSGTPADCVKLALSELLAEKPDLVLSGVNHGPNLGTDVFCSGTVAAAM
HHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCEEECCHHHHHH
EGTLEGLPALAVSVACFQWRDFQAAAELAMDVAENALADNWPNNLLLNLNIPPCHPEQMG
HHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHC
SLRWTRLSIRHYEEQFSRRVDPHSRTYFWLAGEVVKDLETAGDGPRDWPSDVAQIETNSP
CEEEEHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHEEECCCC
SLTPIQPDLFWRGDLSALPAACVANQPVR
CCCCCCCCCEECCCCHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA