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The map label for this gene is aapM [H]

Identifier: 124022918

GI number: 124022918

Start: 1054785

End: 1055813

Strand: Reverse

Name: aapM [H]

Synonym: P9303_12111

Alternate gene names: 124022918

Gene position: 1055813-1054785 (Counterclockwise)

Preceding gene: 124022920

Following gene: 124022917

Centisome position: 39.36

GC content: 53.55

Gene sequence:

>1029_bases
ATGCAGTCTGGGCCAAGCCCTTTTAAACGTCTGAAACGGCACCTATTGGCCACCCCTCTGGATGGCTTGATGACTGTTTT
GCTGCTTGCCCTGCTTGGTTGGGTTGCGACCACAACCCTGCATTGGCTTTTTGTTGATGCGGATTGGCAAGTCGTTAGTC
AAAACCTTCCGCTGTATGCCTTTGGCAGCTATCCACCTCATCAACGTTGGCGCCCATTTCTTTGGATTGCGCTGCTGATA
GGGCTCACCTTATTAACTCTGTTAGGGCCACGTCGGGGTTGGATTCGTAAGGCCTTGCCATTGGTATGGATTGCAATGGT
GCCCTGTGGTGTGGTTCTTCTTGCCGGTGGCCTCGGTTTACTGCCGATCCCTTCTCACGCCTGGGGTGGCCTAACCCTCA
CCCTGCTGCTAACCGCCTGCAGTGGTGCTCTTGCCCTGCCGCTGGGCATCCTTTTGGCACTCGGACGTCAAACCAGGCTG
GCCGTGATCCAACGAAGTTGCAGTATCTATATCGACGTGATGCGGGCTGTTCCTCTAATCGCAGTGTTGTTTTTTGGTCA
GCTGTTGATTCCCCTTTTCCTTCCCATGCATCTAGAGGTGAATCGAGTCTTGCGTGCTGTATTGGCCTTCGCATTATTTG
CTGCCGCATACATCGCTGAAGACGTGCGAGGTGGATTGCAAGCGATCCCACGAACCCAGCGTGAAGCTGCTGCTGTGCTG
GGCCTGAGTCCTAAGCAAATGATTCAACTTGTGGTGTTGCCGCAGGCACTTCGTACAGCTCTACCGGCCCTGACCAACCA
AGCAGTTGGATTACTTCAGAACACCAGCCTGATGGCCATCTTGGGTTTGGTGGAACTGCTGGGGATCAGCCGCAGCCTGT
TGGCCAACCCTGATTTCATTGGTCGGTATCTGGAGGTTTATGTGTGGCTAGCTGGGGTTTACTGGTTGGTTTGCACTGCT
ATGGCCTTACTTGCCCGTCATCTTGAACATCAACTGAGCCCCACAAGGTCTGCTACTTCAAAGCAATGA

Upstream 100 bases:

>100_bases
CTGGCCTATGCGTTTGAGCATGTTCCTTGATCGTTTCTATCCCAAGAGAAGTTGTCCGAATTGTGTTTCTAGTTCCCCTG
AGTACACCTGCTAAATCCTG

Downstream 100 bases:

>100_bases
TTCCAGCCATTCATGCCTCAGGCCTTGTTAAGTGCTTTGGTGATCATCAGCGAGCTCTTGATGAGGTGTCGTTGCAAGTT
GAAAGCGGAGAAGTTTTGGT

Product: amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQSGPSPFKRLKRHLLATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLWIALLI
GLTLLTLLGPRRGWIRKALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRL
AVIQRSCSIYIDVMRAVPLIAVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVL
GLSPKQMIQLVVLPQALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYWLVCTA
MALLARHLEHQLSPTRSATSKQ

Sequences:

>Translated_342_residues
MQSGPSPFKRLKRHLLATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLWIALLI
GLTLLTLLGPRRGWIRKALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRL
AVIQRSCSIYIDVMRAVPLIAVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVL
GLSPKQMIQLVVLPQALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYWLVCTA
MALLARHLEHQLSPTRSATSKQ
>Mature_342_residues
MQSGPSPFKRLKRHLLATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYAFGSYPPHQRWRPFLWIALLI
GLTLLTLLGPRRGWIRKALPLVWIAMVPCGVVLLAGGLGLLPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRL
AVIQRSCSIYIDVMRAVPLIAVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVL
GLSPKQMIQLVVLPQALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFIGRYLEVYVWLAGVYWLVCTA
MALLARHLEHQLSPTRSATSKQ

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=311, Percent_Identity=36.6559485530547, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1786873, Length=208, Percent_Identity=32.2115384615385, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788226, Length=207, Percent_Identity=34.2995169082126, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786874, Length=215, Percent_Identity=26.9767441860465, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI48994930, Length=126, Percent_Identity=31.7460317460317, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788645, Length=183, Percent_Identity=30.6010928961749, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787087, Length=210, Percent_Identity=27.6190476190476, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787086, Length=211, Percent_Identity=28.436018957346, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37373; Mature: 37373

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSGPSPFKRLKRHLLATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYA
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCEEE
FGSYPPHQRWRPFLWIALLIGLTLLTLLGPRRGWIRKALPLVWIAMVPCGVVLLAGGLGL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRLAVIQRSCSIYIDVMRAVPLI
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLSPKQMIQLVVLPQALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHCCHHHH
GRYLEVYVWLAGVYWLVCTAMALLARHLEHQLSPTRSATSKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQSGPSPFKRLKRHLLATPLDGLMTVLLLALLGWVATTTLHWLFVDADWQVVSQNLPLYA
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHCCCCEEE
FGSYPPHQRWRPFLWIALLIGLTLLTLLGPRRGWIRKALPLVWIAMVPCGVVLLAGGLGL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LPIPSHAWGGLTLTLLLTACSGALALPLGILLALGRQTRLAVIQRSCSIYIDVMRAVPLI
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
AVLFFGQLLIPLFLPMHLEVNRVLRAVLAFALFAAAYIAEDVRGGLQAIPRTQREAAAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
GLSPKQMIQLVVLPQALRTALPALTNQAVGLLQNTSLMAILGLVELLGISRSLLANPDFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHCCHHHH
GRYLEVYVWLAGVYWLVCTAMALLARHLEHQLSPTRSATSKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]