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The map label for this gene is ptxB [H]

Identifier: 124022836

GI number: 124022836

Start: 1009572

End: 1010468

Strand: Reverse

Name: ptxB [H]

Synonym: P9303_11291

Alternate gene names: 124022836

Gene position: 1010468-1009572 (Counterclockwise)

Preceding gene: 124022837

Following gene: 124022835

Centisome position: 37.67

GC content: 51.62

Gene sequence:

>897_bases
ATGTTGTCCCAAACTGCGCGTTTAACTGCCGTTACTTTTACAGCGGCTGCTGTTGTCTTTAGCGGTTGCTCTAGTCAAAC
CAACAATGGTGCGTCCACTGACACCAGCAACCCCGACAAACTGATTGTCGCGCTTATTCCTGATGAAAATGCCGCCACGG
TGATTCAGGACAACCAAGGCCTCAAGGATTTTCTCAACGAGAAGCTTGGGAAGGAAATCGAATTGGTTGTCACCACCGAT
TACTCCTCAATGATCGAAGCAGCCCGCAACGATCGCCTCGATCTCGCTTACTTTGGTCCGCTGTCTTACGTCTTAGCGAA
ATCAAAAAGCGAAATCGAACCCTTCGCCGCTCGCATCAAGGGTGGAACAAAAACATATAACTCCTGCCTGATTGGTAATA
CCAAAGCCGGTGTCACCGATTTCGTCTCGATTAAAGGCAAAACCTTTGCGTTCGGTGATCCAGCATCCACATCCAGCCGT
CTGTTCCCTGAACTCACGCTCAAGGAAAATGGCCTGACCAAGGGTGAGGATTACGAAGGTGTGTTCCTCGGTGCCCATGA
TGCCGTGGCCTTGGCCGTTCAGAACGGAAACGCTCAGGCCGGTGGTGTGGCCTGCCCAATTCTTGAATCACTGCAGGAGA
AAGGCAGAATCGACGACACCAAAGTGACGTTGATTGCCAAATCTGCTCCCATTCCCCAATACCCCTGGACGATGCGCTCT
TCGCTGAATCCTCAGCTGAAGGAAACGATTCGAACCGCCTTCATTGAGCTCGATGACGAGAAGGTTCTAAAGCCTTTTAA
GGCGGATGGGTTCGCAGTGATTACGGATCAGGACTACGACGGTATCCGCAAGGCCGGCGATCTGCTCGGACTCGACCTCG
GCAAGTTTGTCAACTAA

Upstream 100 bases:

>100_bases
GAAGATAACGAAATTCATGCCCTTTACCGCCGCAACCTCGAGGTTGCGGTCACTTAAAGACTGCAGGCTCGAATTAAGGC
TTGATTTTCTTTTCCCCACC

Downstream 100 bases:

>100_bases
ACAACGTTCCCTCTCGTCCCGATGGCAATCACCATCGGGACGTTTTTTCTTGATCTCTTTTCATGAGTGCATCCGTTGAT
TCCCATAGCGCCATTCTTCG

Product: phosphate/phosphonate ABC transporter periplasmic protein

Products: 3-phospho-serine [Cytoplasm]; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLSQTARLTAVTFTAAAVVFSGCSSQTNNGASTDTSNPDKLIVALIPDENAATVIQDNQGLKDFLNEKLGKEIELVVTTD
YSSMIEAARNDRLDLAYFGPLSYVLAKSKSEIEPFAARIKGGTKTYNSCLIGNTKAGVTDFVSIKGKTFAFGDPASTSSR
LFPELTLKENGLTKGEDYEGVFLGAHDAVALAVQNGNAQAGGVACPILESLQEKGRIDDTKVTLIAKSAPIPQYPWTMRS
SLNPQLKETIRTAFIELDDEKVLKPFKADGFAVITDQDYDGIRKAGDLLGLDLGKFVN

Sequences:

>Translated_298_residues
MLSQTARLTAVTFTAAAVVFSGCSSQTNNGASTDTSNPDKLIVALIPDENAATVIQDNQGLKDFLNEKLGKEIELVVTTD
YSSMIEAARNDRLDLAYFGPLSYVLAKSKSEIEPFAARIKGGTKTYNSCLIGNTKAGVTDFVSIKGKTFAFGDPASTSSR
LFPELTLKENGLTKGEDYEGVFLGAHDAVALAVQNGNAQAGGVACPILESLQEKGRIDDTKVTLIAKSAPIPQYPWTMRS
SLNPQLKETIRTAFIELDDEKVLKPFKADGFAVITDQDYDGIRKAGDLLGLDLGKFVN
>Mature_298_residues
MLSQTARLTAVTFTAAAVVFSGCSSQTNNGASTDTSNPDKLIVALIPDENAATVIQDNQGLKDFLNEKLGKEIELVVTTD
YSSMIEAARNDRLDLAYFGPLSYVLAKSKSEIEPFAARIKGGTKTYNSCLIGNTKAGVTDFVSIKGKTFAFGDPASTSSR
LFPELTLKENGLTKGEDYEGVFLGAHDAVALAVQNGNAQAGGVACPILESLQEKGRIDDTKVTLIAKSAPIPQYPWTMRS
SLNPQLKETIRTAFIELDDEKVLKPFKADGFAVITDQDYDGIRKAGDLLGLDLGKFVN

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Required for oxidation of phosphite to phosphate [H]

COG id: COG3221

COG function: function code P; ABC-type phosphate/phosphonate transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790543, Length=218, Percent_Identity=26.1467889908257, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015168
- InterPro:   IPR005770 [H]

Pfam domain/function: PF09084 NMT1 [H]

EC number: NA

Molecular weight: Translated: 31958; Mature: 31958

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSQTARLTAVTFTAAAVVFSGCSSQTNNGASTDTSNPDKLIVALIPDENAATVIQDNQG
CCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCC
LKDFLNEKLGKEIELVVTTDYSSMIEAARNDRLDLAYFGPLSYVLAKSKSEIEPFAARIK
HHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCHHHHHHC
GGTKTYNSCLIGNTKAGVTDFVSIKGKTFAFGDPASTSSRLFPELTLKENGLTKGEDYEG
CCCCCCCEEEECCCCCCCEEEEEECCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCE
VFLGAHDAVALAVQNGNAQAGGVACPILESLQEKGRIDDTKVTLIAKSAPIPQYPWTMRS
EEEECCCEEEEEEECCCCCCCCEECHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHC
SLNPQLKETIRTAFIELDDEKVLKPFKADGFAVITDQDYDGIRKAGDLLGLDLGKFVN
CCCHHHHHHHHHHHEECCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MLSQTARLTAVTFTAAAVVFSGCSSQTNNGASTDTSNPDKLIVALIPDENAATVIQDNQG
CCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCC
LKDFLNEKLGKEIELVVTTDYSSMIEAARNDRLDLAYFGPLSYVLAKSKSEIEPFAARIK
HHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCHHHHHHC
GGTKTYNSCLIGNTKAGVTDFVSIKGKTFAFGDPASTSSRLFPELTLKENGLTKGEDYEG
CCCCCCCEEEECCCCCCCEEEEEECCCEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCE
VFLGAHDAVALAVQNGNAQAGGVACPILESLQEKGRIDDTKVTLIAKSAPIPQYPWTMRS
EEEECCCEEEEEEECCCCCCCCEECHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHC
SLNPQLKETIRTAFIELDDEKVLKPFKADGFAVITDQDYDGIRKAGDLLGLDLGKFVN
CCCHHHHHHHHHHHEECCCHHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]