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The map label for this gene is ptxC [H]

Identifier: 124022835

GI number: 124022835

Start: 1008700

End: 1009509

Strand: Reverse

Name: ptxC [H]

Synonym: P9303_11281

Alternate gene names: 124022835

Gene position: 1009509-1008700 (Counterclockwise)

Preceding gene: 124022836

Following gene: 124022834

Centisome position: 37.63

GC content: 55.19

Gene sequence:

>810_bases
ATGAGTGCATCCGTTGATTCCCATAGCGCCATTCTTCGGCGGCATGAGCTGCGATGGCGACAGCAATGTCTCCGTGTTGG
GCTCATCCTCATTGCGGTTGTCGGTTCCCTAGCTGTGGTGGGCCTGTTCGATGCGGAGCGGATCGCGACTGGCTTGCCCG
CGATTTTCAAATTACTGCCGGAAATGTTCCCGCCTGATTTCAGTCGGTGGTCGTTCTGGATCAAACCCTTGATCGACTCC
ATGGCGATGAGCATCGCCGGCACCTCCATCGCAGTGTTTTTTTCAATGTTGCTGTGTCTCTTTGCAGCGCGAAACACAAG
TCCAAACCGTCCGCTGTACTTGGCGGCCACCGGACTTCTCAATGTGACTCGAGCTGTTCCAGAACTAATCCTCGGCATGA
TTCTGGTGGCCGCAGTGGGATTCGGAGCGCTGCCTGGAACCCTCGCGCTCGGGCTCCATTCCATCGGCATGCTTGGCAAG
TTTTATGCCGAAGCGATTGAACTATGTGATCTGGAACCGATCGAAGCAGCTCGATCATCCGGGGCTTCGGAGATGCAGGT
GATCATTCACAGCATTCTTCCCCAGGTGTTTCCAGCCATGGCGGATGTCACCTTTTATCGCTGGGAATACAACTTTCGAG
CCTCGATGGTGGTTGGCGCTGTGGGTGCGGGTGGAATTGGCCTCGAGATCATCAGTGCCCTGCGAATCATGGAATACCAG
CAAGTTTCTGCCTTGCTTTTAGTGGTGCTTGTGGTGGTCACGGCCCTCGATTCGATGAGCAATGCCCTGCGTCACTGGAT
GGTGCAATGA

Upstream 100 bases:

>100_bases
ATCTGCTCGGACTCGACCTCGGCAAGTTTGTCAACTAAACAACGTTCCCTCTCGTCCCGATGGCAATCACCATCGGGACG
TTTTTTCTTGATCTCTTTTC

Downstream 100 bases:

>100_bases
CCCTCACAGCCTCTCCCGATCCAAGACCCCATCTAGTAATCACCAACTATGTGCAGGAAGAGGTGATTGACCTCCTTTCC
ACTTTCGCGCGGGTCACCGC

Product: phosphate/phosphonate ABC transporter permease

Products: 3-phospho-serine [Cytoplasm]; phosphite [Cytoplasm]; ADP; phosphate [Cytoplasm]; alkylphosphonate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSASVDSHSAILRRHELRWRQQCLRVGLILIAVVGSLAVVGLFDAERIATGLPAIFKLLPEMFPPDFSRWSFWIKPLIDS
MAMSIAGTSIAVFFSMLLCLFAARNTSPNRPLYLAATGLLNVTRAVPELILGMILVAAVGFGALPGTLALGLHSIGMLGK
FYAEAIELCDLEPIEAARSSGASEMQVIIHSILPQVFPAMADVTFYRWEYNFRASMVVGAVGAGGIGLEIISALRIMEYQ
QVSALLLVVLVVVTALDSMSNALRHWMVQ

Sequences:

>Translated_269_residues
MSASVDSHSAILRRHELRWRQQCLRVGLILIAVVGSLAVVGLFDAERIATGLPAIFKLLPEMFPPDFSRWSFWIKPLIDS
MAMSIAGTSIAVFFSMLLCLFAARNTSPNRPLYLAATGLLNVTRAVPELILGMILVAAVGFGALPGTLALGLHSIGMLGK
FYAEAIELCDLEPIEAARSSGASEMQVIIHSILPQVFPAMADVTFYRWEYNFRASMVVGAVGAGGIGLEIISALRIMEYQ
QVSALLLVVLVVVTALDSMSNALRHWMVQ
>Mature_268_residues
SASVDSHSAILRRHELRWRQQCLRVGLILIAVVGSLAVVGLFDAERIATGLPAIFKLLPEMFPPDFSRWSFWIKPLIDSM
AMSIAGTSIAVFFSMLLCLFAARNTSPNRPLYLAATGLLNVTRAVPELILGMILVAAVGFGALPGTLALGLHSIGMLGKF
YAEAIELCDLEPIEAARSSGASEMQVIIHSILPQVFPAMADVTFYRWEYNFRASMVVGAVGAGGIGLEIISALRIMEYQQ
VSALLLVVLVVVTALDSMSNALRHWMVQ

Specific function: Probably forms part of a binding-protein-dependent phosphite transporter. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG3639

COG function: function code P; ABC-type phosphate/phosphonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR005769 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29191; Mature: 29060

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASVDSHSAILRRHELRWRQQCLRVGLILIAVVGSLAVVGLFDAERIATGLPAIFKLLP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
EMFPPDFSRWSFWIKPLIDSMAMSIAGTSIAVFFSMLLCLFAARNTSPNRPLYLAATGLL
HHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHH
NVTRAVPELILGMILVAAVGFGALPGTLALGLHSIGMLGKFYAEAIELCDLEPIEAARSS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
GASEMQVIIHSILPQVFPAMADVTFYRWEYNFRASMVVGAVGAGGIGLEIISALRIMEYQ
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QVSALLLVVLVVVTALDSMSNALRHWMVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SASVDSHSAILRRHELRWRQQCLRVGLILIAVVGSLAVVGLFDAERIATGLPAIFKLLP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
EMFPPDFSRWSFWIKPLIDSMAMSIAGTSIAVFFSMLLCLFAARNTSPNRPLYLAATGLL
HHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHH
NVTRAVPELILGMILVAAVGFGALPGTLALGLHSIGMLGKFYAEAIELCDLEPIEAARSS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
GASEMQVIIHSILPQVFPAMADVTFYRWEYNFRASMVVGAVGAGGIGLEIISALRIMEYQ
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QVSALLLVVLVVVTALDSMSNALRHWMVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-phospho-serine [Periplasm]; phosphite [Periplasm]; H2O; phosphate [Periplasm]; alkylphosphonate [Periplasm] [C]

Specific reaction: H2O + ATP + 3-phospho-serine [Periplasm] = ADP + phosphate + 3-phospho-serine [Cytoplasm] ATP + phosphite [Periplasm] + H2O = phosphite [Cytoplasm] + ADP + phosphate phosphate [Periplasm] + ATP + H2O = ADP + phosphate [Cytoplasm] + phosphate [Cytoplasm] A

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9791102 [H]