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The map label for this gene is lgrD [H]

Identifier: 124022793

GI number: 124022793

Start: 971932

End: 978531

Strand: Reverse

Name: lgrD [H]

Synonym: P9303_10861

Alternate gene names: 124022793

Gene position: 978531-971932 (Counterclockwise)

Preceding gene: 124022796

Following gene: 124022792

Centisome position: 36.48

GC content: 43.33

Gene sequence:

>6600_bases
ATGTCTATAGTTGAAACTGCGAGCCTTCATTTATACATATCTTATCTAACAGAGCAAAAAAATATCATGACAATGTTGAC
CAGTCGCATCGGACTACCTAGCAATCAAAACTCAGTCTCGAAAATAGGATTTAGCGAAGCACGCAGCCTCTTCATTTCAA
ATCCAAAAGGAAATCTACGCCTAAGAGACTTCCTACTTGACACATGCAAACTCAATGAATATTCAAACCTACATGCCAAT
TATCCAATTAGCAAGATTATTGATGTGATTCGATTGGATCAACCAAACTTCTCCGAATTTACTAATATTGGCGCTGACTA
TACCTACCTTCCATACAATAGTCTTCATCTGGATGGTATTGAAGCTATATTACGGACCTCATTCTCAAGGAGACGCCCAT
CGAAGGATGTTTCATTTAAGTTGAGAATAAACCAACACAATAAACTTGCAATACGAACGCGTCATCCAGACCTTCTTCCG
GCTATCAAGCAATCGTTGCCAATATTGCTTCATCGATTAGAGAATCTACACGATGAACTTGATCACAACATCGGAGATCT
CAGCTGGATGGACAGAGAGCAAAGGAAATCAATACTAATTCAGTCAGCAACGCCAAAGAATAAAAAGATTGCTGTTGACT
TCCTCGATAGACTTGTAAATAAAACTAAAGAAAATCCGAACCATCTGGCCTTAAAATACAAAGAGAAATCGCTAACTTAT
AAGGAACTTATGGCAGCTGCTGATACACTTGCTTTACGATTAAGACAACTAATTAAAGAGAGCAATAGTAGCGAACCACT
TTTTGGTATTTGCTTGCCGAGAGGTTGTGAGATGATTATCGCCTTAGTGGGAATATTACGTTCAGGGGCTGGTTATTTAC
CTCTTGACCCGACTAATCCACGCGATCGCATTGACTATATCCTAAAGGATGCAAAACCTGTAGGTGTGATTATTGATGAT
ACAACAATATCCATTGTCGAGGCAGTGGTTAATATAAAAAAAGTGAGGATACCAACAGAAGAAAACTGGAGGGAAATACT
CAATGAACCAATAGCTAATACACTCTCAGAGAGTGAGGCAATCGCTTATATCATCTACACCTCCGGGACAACTGGGCTGC
CAAAAGGTGTGGTTATAGAGCGAGGTAATCTTGCAGCATTTATCTCGGCAGCTGAAGAAATTGCAAGCGGAGAGCCAGGG
CAACGCTGGCAACAATTTGCATCGATTAATTTTGATGCGTCAATATTAGAAATAAGTAGCGCATTAGCAAGAGGTTCGAC
CCTTGTGATCGCACCATCCGAAATTCGTTCTAACCCAGAAGCATTATTTGAGTTTCTTGAGCAGGAAGGAATCACACATG
CATTCATTCCCCCAGCCATGCTGCGGTTATTACCTAGGAGAAAACTTCCTGCTCTAACTGACATCTATGTTGGAGGAGAG
GCCTCAGACGATCTCACAGTCTCCTTCTGGTCGAGGGCTACACGCCTGTGGAATGTTTATGGGCCTACAGAAACCACTGT
GATCTGCTCAGCAAAATTAATGACATCTCAGCTTTCTGCTACCGATCTGGGTGGTCCTCTGCCTGGGTACAGCATGTTTG
TTCTTGATCAAAAATTGGAACCTGTCCCGCCAGGTATTATTGGCGAAATCTACATAGCTGGCAACGCTGTATCTAGGGGA
TATCTAAACAGATCTACAACAACAGCAGAGCGGTTCTTCAGGAACCCATTCGGAGAAGGGCGTCTCTATCGCACAGGAGA
TTTAGCAAGACACTTTCCAAGTGGAGAACTCGAATATCTAGGACGCAACGATTTCCAGGTAAAAATTAGAGGTTTTAGAA
TAGAGCTGGGCGAAGTCGAGTCAACTATCGCAGATGTAAATGGAGTAACAGGAGTCTTCGTCACTGTAATCGATGAGCCA
AGTGGCAAAACCCTTGTTGCATGGTTTACCACAAATCCTGAAGGGCCCGAGGCCACATCACTTCGCAAGACAATAAGCGA
ACAACTAACGCACTATATGGTGCCAACATATTTGATTAAGGTTGACACATTCCCTGTAAATATTAGTGGAAAAATCGATC
GCTCACGTCTGCCAATGCCTGAGAACATAAAATCTGAACATGAATCAGAACCATTAACAGGACTTGAAAGCAAGGTTCAA
TTAATTTGGTCAGAAATCCTAGAAATACCAAAAGAGAGAATCAAACTAGATTCGAATTTCTTTCATCTAGGCGGACACTC
ATTAAATGCGGCAATAGCATGCCATAAAATCGCTGCAGAACTCGAACAAGGTCTCTCACCGAAAACTCTGTTCGAGAATC
CTGTTCTCAAGGATTTCTCAGGCTGCCTTTCTAATCAATCAAAAACAAATCAGTTAGAGCCATTAATAGCTACAGGTTTG
ACGAAAACAAGAATGCCAGGTGCACTACTTGAAATGATGCTCCACCGCTCCATTCAAAATGGTCAAGATACTGCCTACAC
CATTGTTGTTGATATTGACTTTGAGTCTGATATCAATCCTCTAAAATTACGCGCAGCCTTTTCCGAACTCTTGGCTGGGG
ATCCTATTTTTAGCTCACACTTTCTTGAACAGGAAGGCAAGACCTATATCAAGCATGATCCAACCACAGCAATCATCATC
CCGCTGCTTACTGATACGGAAAAGCAGACACGGATAAATGAGTTCAGGGGCACATCATTTGACTTACTTAAAGCACCACT
ATGGCGTGCTGAAATTATCATTAATGAAAGGCAAAGTCACCTACTACTTGCAATTAACCATGGCATATTCGATGGATGGT
CACTAACTCTTATGCTCAGAGAACTTGCAGAACGCTATGAGGCAAGTGTAAGTTCAGATACATATAATCGTACCGCCCCA
ACCATGCTGGATTATGGGGCGTGGCTAAGCAGCCACAAAGAAATGAGAGACGCCTCTATCTCTTACTGGGATAAGAAACT
AAGTGGAGGGAGTTGCAAGACAAATCTACCTGGTTCATCTCATCCAGGGGCAGCCAGCCTGAATTTAGAGAAGCCTATCA
ACTTACCTTACTTAGCAACATGTGAATTAAAGGAGTTAGCTACAGACCTAGATGTAACTCTCCCTCCAGTACTATTCGCG
GCATATCTTGTTTGGCTTTGGAGAATAAGTGGGCAAGATAACCTAACAGTTGGCTATCCATATGCTGGTCGAGATGTACT
CAATAGTGAACGTGTATTTGGGATGTTTGTGCAAATGGGATTCCTACGTATTGATATTGATCCTGAGGAACAATTTACAT
CTCTAATAAAACGTGTTGCCAAACAAATGATCGAAGATCGAGATCATCTGCTCGCATCTCCATACGATGCTGAAATCTCG
AGCGCAGGTGCGCCAAATATCCTATTTAGTCTCCAGAGTGGGATTGGCCTTGAAGGAACACATGGAACTGTCAAGTTCAA
AGCCCATGAACATCCTTCTCAAGCCAGCAAGGCTGATATCGCTGCAATTCTCTACGAAAATTCTAATGGAGAACTTCAGG
GAAGAATAGAATATGACAGTGCGGTCATGGAAGAAGCGGAAATAGAGCCACTGTTTGAGTGTTTCAACCATCTTTTAAAC
AGTTTAGCAAAATACGCTAAGCGAGAAATTTCTGATCTGCCATACCTTTCTCCCAAGCAAGTAAGTCAACTTATTGAATT
CTCTGGTGAAGTGGGAGATTTTAGGGAAGATAACACAACATTAATCAATTCCCTTCGGCAAGTTATTGCAGATCACCCAG
AAGAGATTGCTATTGAGAGCAACCATGAGCAAATCAGTTATGCCGAGCTCGATCAGATTACTAACAAGCTAGCAAAAAGG
ATCATTTTTGAAGGTGAACCAGGTTCTGAAAAACTTATTGCTCTCTCAGGAATAAAGAGCAGCTCGCTTGTTATGGCAAC
CATTGCAATCCTAAAAGCTGGTTGCGCCTATGTGCCTATCGATCCAAATTATCCTGCCGAACGCATCGAGTACATCCTAA
AGGACGCAAACATTCAACTCATGTTGGCTGATGCTGATGCCAATTCAGTTATCAATAAGATCAGTCATCAACAACTAACA
TTGATTGATCCACAACAGGTGGTAGGTAAAGAGGTAGATCTTGGTACAACTGATTTACAAGACATTAACGATGTCGAACC
TCGCTCCCTGGCGTATGTCATCTACACCTCAGGTTCCACTGGCAAACCCAAAGGAGTGATGGTAGAGCACAGAACTATAC
CAAGGATGATTGATGCAGCTGCAGAATTAATGAACTTCACAAGCAGTGATCGAATGCTACTACTTGGCACATTAAACTTT
GATGCAAGTGTCCTTCAAATGTTCACCCCATTACTTAAAGGGGGAACACTGATTATTCCACCAGCTGATGCTGAACGTGA
TCCTGACGGACTACATCAACTCATCAATGACAAAGGGGTGACTCATCTAGTTGGTACCCCTGCTCTACTGAGGAACCTAC
CCAGGGAACCTCTATCAAAGCTTCGTTTTATGGGGTTCGGTGGCGAAGCAATCGACACGTCTACAGCAAGTTTCTGGGCA
GAAAAGACATGCCTGTATTCCCTGTATGGACCTACAGAAACGACCGTAATGTGCTCTGGCGGCAGGATCCTTCCTGGAGC
AAATCCGCGAATTGTAGGAAAACCACTGATGGGCTATTCAATCAATTTGCGCGATCAACAACTGCAACCAGTGCCATTGG
GCGCCATAGGAGAACTAGTAATCAGCGGAGGAACTGCTCGCGGATACTTAAATCGTTATGACCTAACACTAAATCGATTC
CGTATCGATCCTGACGGTGTTGATCCATACCAACGTGTATACCTCAGCGGAGACCTAGGTCGCTTCCTTCCTGATGGAAC
CATTGAATTTCTAGGCAGAAATGACGATCAAATCAAACTAAGAGGTTATCGAATCGAACTCGGGGAGATTGAGGCATCCA
TGCAATCGGCTCCGGGGGTAACAAATGCAACAGCAATGGTGCGTGGAGAAAACGATAATCGCATGTTAATTGGCTACCTA
ACAGGAAACGAAGGCCTTGACATAGATGAAGTTCGTCAACATTGCCAAGAACAATTACCTGGGTATATGGTGCCTTCAAG
ATTCATCAAACTTGAAAACATGCCATTGAATCCTAATGGCAAACTTGACCGGAATGCGCTGCCTGATGTCTCGTTCGTGT
CGACATCTGAACCGCCAAAAGTGGGCCTTGAACAGAAAGTAGCAGCCGTATGGCAAGACCTTCTGCATCTAAAGAACATT
GGGCGCAAAGATGACTTTTTCCACCTGGGAGGAAACTCACTGCTAGCTGCTCGACTCCAGACACTGCTAAGAGAGCGATG
TGATCTAGAGATCTCAACAGCAAACCTCTACGCCCATCCTACTATTGCAGGATTAACCGGCGAAAAAAAGGTCTCGGAGA
TCAATCAGGCGATCAACACAGCGACCGTATCGATCCAAATCAATCAACCAGTAGCACCTCGTTCTAAGTTCAAAAAACAG
CCCAACGTACTACTTACAGGGGCTTCTGGCTTTCTAGGTGTTTATCTGTTGGCGGAACTTCAAAGCCGCGCTGGTGAAAT
TATCTGTCTAGCAAGAGGCAAGAGTGATCAACAAATAACAGATAACCTCAAGAAACATGCCGAGCGCAGCAATCTTGAAA
TCGACTTTAATCAAATCCGCGTGATCCGAGGCGACCTTTCTAAAAAAGGGCTCGGTCTTAGAGCTTACAAATATGATCAG
CTAACAAATGTTGTTGATCAAATCATCCACTGTGGGGCGTGGATCAACCACCTCTACTCCTACAGCTCACTTAGATCAGC
GAATGTTGGTTCAACAGTTGAACTAATCAAATTAGCACTAGCTGGCAAATATCGAACCCCATTATGTTTCATCTCGACGG
AATCAGCTGCTACTAATCTTCGAGGAATTAGTTGCGTTGAAGAAGCTATTCTCGACCCAGTCAAGAATCAGCCAATCTCT
GACAACGGATACATGCTAAGCAAGTGGGTATCCGAATTAATACTCGCCAATGCCGTTCATAATCATGGTCTTGATTGCTT
GATTGCTCGTCCAGGCAACATTACTGGAGACAGTAGAACTGGCTTCAGCAATTACAGCAATAACCATTTTTGGATGTACA
CCAAGGGCTGCCTTCAGATGGGAATGGCGCCATTAATCCAACAGCATGTGGAGATGACACCAGTCGATGTTCTTGCAAGA
GCCATTGTTGCTCTCGTATTCGATGCGCAAGAAGGCCTCCGCGTAGCAAATCTAAGCAATCCAATCAACATTCCATGGGA
ACAATTCTTCAAAGCAATAACTCAGATCACAGGCCAAGAGATTGCAATGGTCGAAGCAAAATCGTGGCAAACAAAGCTCA
ATGAGATTAACACAGACAATACACTATATATGCTTCGTGATCTATATAGCGAGAACATCACTACAGCCTCTCCCAAAGTC
AACAGATCTTCTAGCCAAGCTGTTCTGAACAGCCTAGGAGTTTCCATAGATTCAGACCCTAGGATGCTTGCCAAACTCTA
TGTTCCTTACCTAATTGAGCAAGGATTCCTAATACCATGA

Upstream 100 bases:

>100_bases
TCATTCAAATGAAGATCTGACTCAGTCCAGCATAGAGCTTGATATTTCAAAAAAAGTTGGTCATTCTCTAATTAGTGTTG
CAGAGGAGCTATCAATACCC

Downstream 100 bases:

>100_bases
AAATTCACATCATCGACCTTCGTCAATCATCAGGTGATCAGAGTTGTCTAGACAATAGTTTCGACAATATTAAGCGTAGG
CTATTCCTACGACGCTCAGC

Product: hypothetical protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-Leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent glycine adenylase; GlyA; Glycine activase; Linear gramicidin--PCP reductase [H]

Number of amino acids: Translated: 2199; Mature: 2198

Protein sequence:

>2199_residues
MSIVETASLHLYISYLTEQKNIMTMLTSRIGLPSNQNSVSKIGFSEARSLFISNPKGNLRLRDFLLDTCKLNEYSNLHAN
YPISKIIDVIRLDQPNFSEFTNIGADYTYLPYNSLHLDGIEAILRTSFSRRRPSKDVSFKLRINQHNKLAIRTRHPDLLP
AIKQSLPILLHRLENLHDELDHNIGDLSWMDREQRKSILIQSATPKNKKIAVDFLDRLVNKTKENPNHLALKYKEKSLTY
KELMAAADTLALRLRQLIKESNSSEPLFGICLPRGCEMIIALVGILRSGAGYLPLDPTNPRDRIDYILKDAKPVGVIIDD
TTISIVEAVVNIKKVRIPTEENWREILNEPIANTLSESEAIAYIIYTSGTTGLPKGVVIERGNLAAFISAAEEIASGEPG
QRWQQFASINFDASILEISSALARGSTLVIAPSEIRSNPEALFEFLEQEGITHAFIPPAMLRLLPRRKLPALTDIYVGGE
ASDDLTVSFWSRATRLWNVYGPTETTVICSAKLMTSQLSATDLGGPLPGYSMFVLDQKLEPVPPGIIGEIYIAGNAVSRG
YLNRSTTTAERFFRNPFGEGRLYRTGDLARHFPSGELEYLGRNDFQVKIRGFRIELGEVESTIADVNGVTGVFVTVIDEP
SGKTLVAWFTTNPEGPEATSLRKTISEQLTHYMVPTYLIKVDTFPVNISGKIDRSRLPMPENIKSEHESEPLTGLESKVQ
LIWSEILEIPKERIKLDSNFFHLGGHSLNAAIACHKIAAELEQGLSPKTLFENPVLKDFSGCLSNQSKTNQLEPLIATGL
TKTRMPGALLEMMLHRSIQNGQDTAYTIVVDIDFESDINPLKLRAAFSELLAGDPIFSSHFLEQEGKTYIKHDPTTAIII
PLLTDTEKQTRINEFRGTSFDLLKAPLWRAEIIINERQSHLLLAINHGIFDGWSLTLMLRELAERYEASVSSDTYNRTAP
TMLDYGAWLSSHKEMRDASISYWDKKLSGGSCKTNLPGSSHPGAASLNLEKPINLPYLATCELKELATDLDVTLPPVLFA
AYLVWLWRISGQDNLTVGYPYAGRDVLNSERVFGMFVQMGFLRIDIDPEEQFTSLIKRVAKQMIEDRDHLLASPYDAEIS
SAGAPNILFSLQSGIGLEGTHGTVKFKAHEHPSQASKADIAAILYENSNGELQGRIEYDSAVMEEAEIEPLFECFNHLLN
SLAKYAKREISDLPYLSPKQVSQLIEFSGEVGDFREDNTTLINSLRQVIADHPEEIAIESNHEQISYAELDQITNKLAKR
IIFEGEPGSEKLIALSGIKSSSLVMATIAILKAGCAYVPIDPNYPAERIEYILKDANIQLMLADADANSVINKISHQQLT
LIDPQQVVGKEVDLGTTDLQDINDVEPRSLAYVIYTSGSTGKPKGVMVEHRTIPRMIDAAAELMNFTSSDRMLLLGTLNF
DASVLQMFTPLLKGGTLIIPPADAERDPDGLHQLINDKGVTHLVGTPALLRNLPREPLSKLRFMGFGGEAIDTSTASFWA
EKTCLYSLYGPTETTVMCSGGRILPGANPRIVGKPLMGYSINLRDQQLQPVPLGAIGELVISGGTARGYLNRYDLTLNRF
RIDPDGVDPYQRVYLSGDLGRFLPDGTIEFLGRNDDQIKLRGYRIELGEIEASMQSAPGVTNATAMVRGENDNRMLIGYL
TGNEGLDIDEVRQHCQEQLPGYMVPSRFIKLENMPLNPNGKLDRNALPDVSFVSTSEPPKVGLEQKVAAVWQDLLHLKNI
GRKDDFFHLGGNSLLAARLQTLLRERCDLEISTANLYAHPTIAGLTGEKKVSEINQAINTATVSIQINQPVAPRSKFKKQ
PNVLLTGASGFLGVYLLAELQSRAGEIICLARGKSDQQITDNLKKHAERSNLEIDFNQIRVIRGDLSKKGLGLRAYKYDQ
LTNVVDQIIHCGAWINHLYSYSSLRSANVGSTVELIKLALAGKYRTPLCFISTESAATNLRGISCVEEAILDPVKNQPIS
DNGYMLSKWVSELILANAVHNHGLDCLIARPGNITGDSRTGFSNYSNNHFWMYTKGCLQMGMAPLIQQHVEMTPVDVLAR
AIVALVFDAQEGLRVANLSNPINIPWEQFFKAITQITGQEIAMVEAKSWQTKLNEINTDNTLYMLRDLYSENITTASPKV
NRSSSQAVLNSLGVSIDSDPRMLAKLYVPYLIEQGFLIP

Sequences:

>Translated_2199_residues
MSIVETASLHLYISYLTEQKNIMTMLTSRIGLPSNQNSVSKIGFSEARSLFISNPKGNLRLRDFLLDTCKLNEYSNLHAN
YPISKIIDVIRLDQPNFSEFTNIGADYTYLPYNSLHLDGIEAILRTSFSRRRPSKDVSFKLRINQHNKLAIRTRHPDLLP
AIKQSLPILLHRLENLHDELDHNIGDLSWMDREQRKSILIQSATPKNKKIAVDFLDRLVNKTKENPNHLALKYKEKSLTY
KELMAAADTLALRLRQLIKESNSSEPLFGICLPRGCEMIIALVGILRSGAGYLPLDPTNPRDRIDYILKDAKPVGVIIDD
TTISIVEAVVNIKKVRIPTEENWREILNEPIANTLSESEAIAYIIYTSGTTGLPKGVVIERGNLAAFISAAEEIASGEPG
QRWQQFASINFDASILEISSALARGSTLVIAPSEIRSNPEALFEFLEQEGITHAFIPPAMLRLLPRRKLPALTDIYVGGE
ASDDLTVSFWSRATRLWNVYGPTETTVICSAKLMTSQLSATDLGGPLPGYSMFVLDQKLEPVPPGIIGEIYIAGNAVSRG
YLNRSTTTAERFFRNPFGEGRLYRTGDLARHFPSGELEYLGRNDFQVKIRGFRIELGEVESTIADVNGVTGVFVTVIDEP
SGKTLVAWFTTNPEGPEATSLRKTISEQLTHYMVPTYLIKVDTFPVNISGKIDRSRLPMPENIKSEHESEPLTGLESKVQ
LIWSEILEIPKERIKLDSNFFHLGGHSLNAAIACHKIAAELEQGLSPKTLFENPVLKDFSGCLSNQSKTNQLEPLIATGL
TKTRMPGALLEMMLHRSIQNGQDTAYTIVVDIDFESDINPLKLRAAFSELLAGDPIFSSHFLEQEGKTYIKHDPTTAIII
PLLTDTEKQTRINEFRGTSFDLLKAPLWRAEIIINERQSHLLLAINHGIFDGWSLTLMLRELAERYEASVSSDTYNRTAP
TMLDYGAWLSSHKEMRDASISYWDKKLSGGSCKTNLPGSSHPGAASLNLEKPINLPYLATCELKELATDLDVTLPPVLFA
AYLVWLWRISGQDNLTVGYPYAGRDVLNSERVFGMFVQMGFLRIDIDPEEQFTSLIKRVAKQMIEDRDHLLASPYDAEIS
SAGAPNILFSLQSGIGLEGTHGTVKFKAHEHPSQASKADIAAILYENSNGELQGRIEYDSAVMEEAEIEPLFECFNHLLN
SLAKYAKREISDLPYLSPKQVSQLIEFSGEVGDFREDNTTLINSLRQVIADHPEEIAIESNHEQISYAELDQITNKLAKR
IIFEGEPGSEKLIALSGIKSSSLVMATIAILKAGCAYVPIDPNYPAERIEYILKDANIQLMLADADANSVINKISHQQLT
LIDPQQVVGKEVDLGTTDLQDINDVEPRSLAYVIYTSGSTGKPKGVMVEHRTIPRMIDAAAELMNFTSSDRMLLLGTLNF
DASVLQMFTPLLKGGTLIIPPADAERDPDGLHQLINDKGVTHLVGTPALLRNLPREPLSKLRFMGFGGEAIDTSTASFWA
EKTCLYSLYGPTETTVMCSGGRILPGANPRIVGKPLMGYSINLRDQQLQPVPLGAIGELVISGGTARGYLNRYDLTLNRF
RIDPDGVDPYQRVYLSGDLGRFLPDGTIEFLGRNDDQIKLRGYRIELGEIEASMQSAPGVTNATAMVRGENDNRMLIGYL
TGNEGLDIDEVRQHCQEQLPGYMVPSRFIKLENMPLNPNGKLDRNALPDVSFVSTSEPPKVGLEQKVAAVWQDLLHLKNI
GRKDDFFHLGGNSLLAARLQTLLRERCDLEISTANLYAHPTIAGLTGEKKVSEINQAINTATVSIQINQPVAPRSKFKKQ
PNVLLTGASGFLGVYLLAELQSRAGEIICLARGKSDQQITDNLKKHAERSNLEIDFNQIRVIRGDLSKKGLGLRAYKYDQ
LTNVVDQIIHCGAWINHLYSYSSLRSANVGSTVELIKLALAGKYRTPLCFISTESAATNLRGISCVEEAILDPVKNQPIS
DNGYMLSKWVSELILANAVHNHGLDCLIARPGNITGDSRTGFSNYSNNHFWMYTKGCLQMGMAPLIQQHVEMTPVDVLAR
AIVALVFDAQEGLRVANLSNPINIPWEQFFKAITQITGQEIAMVEAKSWQTKLNEINTDNTLYMLRDLYSENITTASPKV
NRSSSQAVLNSLGVSIDSDPRMLAKLYVPYLIEQGFLIP
>Mature_2198_residues
SIVETASLHLYISYLTEQKNIMTMLTSRIGLPSNQNSVSKIGFSEARSLFISNPKGNLRLRDFLLDTCKLNEYSNLHANY
PISKIIDVIRLDQPNFSEFTNIGADYTYLPYNSLHLDGIEAILRTSFSRRRPSKDVSFKLRINQHNKLAIRTRHPDLLPA
IKQSLPILLHRLENLHDELDHNIGDLSWMDREQRKSILIQSATPKNKKIAVDFLDRLVNKTKENPNHLALKYKEKSLTYK
ELMAAADTLALRLRQLIKESNSSEPLFGICLPRGCEMIIALVGILRSGAGYLPLDPTNPRDRIDYILKDAKPVGVIIDDT
TISIVEAVVNIKKVRIPTEENWREILNEPIANTLSESEAIAYIIYTSGTTGLPKGVVIERGNLAAFISAAEEIASGEPGQ
RWQQFASINFDASILEISSALARGSTLVIAPSEIRSNPEALFEFLEQEGITHAFIPPAMLRLLPRRKLPALTDIYVGGEA
SDDLTVSFWSRATRLWNVYGPTETTVICSAKLMTSQLSATDLGGPLPGYSMFVLDQKLEPVPPGIIGEIYIAGNAVSRGY
LNRSTTTAERFFRNPFGEGRLYRTGDLARHFPSGELEYLGRNDFQVKIRGFRIELGEVESTIADVNGVTGVFVTVIDEPS
GKTLVAWFTTNPEGPEATSLRKTISEQLTHYMVPTYLIKVDTFPVNISGKIDRSRLPMPENIKSEHESEPLTGLESKVQL
IWSEILEIPKERIKLDSNFFHLGGHSLNAAIACHKIAAELEQGLSPKTLFENPVLKDFSGCLSNQSKTNQLEPLIATGLT
KTRMPGALLEMMLHRSIQNGQDTAYTIVVDIDFESDINPLKLRAAFSELLAGDPIFSSHFLEQEGKTYIKHDPTTAIIIP
LLTDTEKQTRINEFRGTSFDLLKAPLWRAEIIINERQSHLLLAINHGIFDGWSLTLMLRELAERYEASVSSDTYNRTAPT
MLDYGAWLSSHKEMRDASISYWDKKLSGGSCKTNLPGSSHPGAASLNLEKPINLPYLATCELKELATDLDVTLPPVLFAA
YLVWLWRISGQDNLTVGYPYAGRDVLNSERVFGMFVQMGFLRIDIDPEEQFTSLIKRVAKQMIEDRDHLLASPYDAEISS
AGAPNILFSLQSGIGLEGTHGTVKFKAHEHPSQASKADIAAILYENSNGELQGRIEYDSAVMEEAEIEPLFECFNHLLNS
LAKYAKREISDLPYLSPKQVSQLIEFSGEVGDFREDNTTLINSLRQVIADHPEEIAIESNHEQISYAELDQITNKLAKRI
IFEGEPGSEKLIALSGIKSSSLVMATIAILKAGCAYVPIDPNYPAERIEYILKDANIQLMLADADANSVINKISHQQLTL
IDPQQVVGKEVDLGTTDLQDINDVEPRSLAYVIYTSGSTGKPKGVMVEHRTIPRMIDAAAELMNFTSSDRMLLLGTLNFD
ASVLQMFTPLLKGGTLIIPPADAERDPDGLHQLINDKGVTHLVGTPALLRNLPREPLSKLRFMGFGGEAIDTSTASFWAE
KTCLYSLYGPTETTVMCSGGRILPGANPRIVGKPLMGYSINLRDQQLQPVPLGAIGELVISGGTARGYLNRYDLTLNRFR
IDPDGVDPYQRVYLSGDLGRFLPDGTIEFLGRNDDQIKLRGYRIELGEIEASMQSAPGVTNATAMVRGENDNRMLIGYLT
GNEGLDIDEVRQHCQEQLPGYMVPSRFIKLENMPLNPNGKLDRNALPDVSFVSTSEPPKVGLEQKVAAVWQDLLHLKNIG
RKDDFFHLGGNSLLAARLQTLLRERCDLEISTANLYAHPTIAGLTGEKKVSEINQAINTATVSIQINQPVAPRSKFKKQP
NVLLTGASGFLGVYLLAELQSRAGEIICLARGKSDQQITDNLKKHAERSNLEIDFNQIRVIRGDLSKKGLGLRAYKYDQL
TNVVDQIIHCGAWINHLYSYSSLRSANVGSTVELIKLALAGKYRTPLCFISTESAATNLRGISCVEEAILDPVKNQPISD
NGYMLSKWVSELILANAVHNHGLDCLIARPGNITGDSRTGFSNYSNNHFWMYTKGCLQMGMAPLIQQHVEMTPVDVLARA
IVALVFDAQEGLRVANLSNPINIPWEQFFKAITQITGQEIAMVEAKSWQTKLNEINTDNTLYMLRDLYSENITTASPKVN
RSSSQAVLNSLGVSIDSDPRMLAKLYVPYLIEQGFLIP

Specific function: Activates the 13th to the 16th (Trp, D-Leu, Trp and Gly) amino acids in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 14th (D-Leu) amino acid. It also catalyzes

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=540, Percent_Identity=25.9259259259259, Blast_Score=139, Evalue=3e-32,
Organism=Homo sapiens, GI42544132, Length=519, Percent_Identity=22.3506743737958, Blast_Score=99, Evalue=4e-20,
Organism=Homo sapiens, GI38505220, Length=462, Percent_Identity=25.1082251082251, Blast_Score=95, Evalue=7e-19,
Organism=Homo sapiens, GI122937307, Length=458, Percent_Identity=22.4890829694323, Blast_Score=91, Evalue=1e-17,
Organism=Homo sapiens, GI157311624, Length=367, Percent_Identity=25.8855585831063, Blast_Score=90, Evalue=3e-17,
Organism=Homo sapiens, GI157311622, Length=367, Percent_Identity=25.8855585831063, Blast_Score=90, Evalue=3e-17,
Organism=Homo sapiens, GI115511026, Length=505, Percent_Identity=21.5841584158416, Blast_Score=87, Evalue=2e-16,
Organism=Homo sapiens, GI58082049, Length=360, Percent_Identity=24.7222222222222, Blast_Score=83, Evalue=3e-15,
Organism=Homo sapiens, GI12669909, Length=367, Percent_Identity=24.2506811989101, Blast_Score=75, Evalue=1e-12,
Organism=Homo sapiens, GI4758332, Length=367, Percent_Identity=24.2506811989101, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI13375727, Length=308, Percent_Identity=24.3506493506494, Blast_Score=74, Evalue=2e-12,
Organism=Escherichia coli, GI1786801, Length=1052, Percent_Identity=27.4714828897338, Blast_Score=278, Evalue=4e-75,
Organism=Escherichia coli, GI1789201, Length=370, Percent_Identity=27.8378378378378, Blast_Score=99, Evalue=3e-21,
Organism=Escherichia coli, GI145693145, Length=525, Percent_Identity=25.3333333333333, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1786810, Length=510, Percent_Identity=26.8627450980392, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI221142682, Length=494, Percent_Identity=22.8744939271255, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1790505, Length=596, Percent_Identity=22.9865771812081, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1788107, Length=550, Percent_Identity=22, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17556356, Length=528, Percent_Identity=29.3560606060606, Blast_Score=192, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17550940, Length=1128, Percent_Identity=21.6312056737589, Blast_Score=146, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI32564420, Length=416, Percent_Identity=27.1634615384615, Blast_Score=115, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI32564422, Length=416, Percent_Identity=27.1634615384615, Blast_Score=115, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17560308, Length=554, Percent_Identity=22.3826714801444, Blast_Score=77, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17558820, Length=493, Percent_Identity=22.5152129817444, Blast_Score=77, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=1147, Percent_Identity=27.027027027027, Blast_Score=310, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6319699, Length=366, Percent_Identity=22.1311475409836, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648676, Length=581, Percent_Identity=30.6368330464716, Blast_Score=197, Evalue=8e-50,
Organism=Drosophila melanogaster, GI24582852, Length=513, Percent_Identity=23.5867446393762, Blast_Score=88, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24648260, Length=463, Percent_Identity=21.5982721382289, Blast_Score=75, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24581924, Length=530, Percent_Identity=22.4528301886792, Blast_Score=69, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013120
- InterPro:   IPR016040
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR010080 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF07993 NAD_binding_4; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 244108; Mature: 243977

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVETASLHLYISYLTEQKNIMTMLTSRIGLPSNQNSVSKIGFSEARSLFISNPKGNLR
CCCCEEEEEEEEEEEHHCCHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHEEEECCCCCEE
LRDFLLDTCKLNEYSNLHANYPISKIIDVIRLDQPNFSEFTNIGADYTYLPYNSLHLDGI
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCCCCEEHHHH
EAILRTSFSRRRPSKDVSFKLRINQHNKLAIRTRHPDLLPAIKQSLPILLHRLENLHDEL
HHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
DHNIGDLSWMDREQRKSILIQSATPKNKKIAVDFLDRLVNKTKENPNHLALKYKEKSLTY
CCCCCCCHHCCHHHHHCEEEECCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
KELMAAADTLALRLRQLIKESNSSEPLFGICLPRGCEMIIALVGILRSGAGYLPLDPTNP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCC
RDRIDYILKDAKPVGVIIDDTTISIVEAVVNIKKVRIPTEENWREILNEPIANTLSESEA
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCE
IAYIIYTSGTTGLPKGVVIERGNLAAFISAAEEIASGEPGQRWQQFASINFDASILEISS
EEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHH
ALARGSTLVIAPSEIRSNPEALFEFLEQEGITHAFIPPAMLRLLPRRKLPALTDIYVGGE
HHHCCCEEEEECHHHCCCHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCCCCEEEEECCC
ASDDLTVSFWSRATRLWNVYGPTETTVICSAKLMTSQLSATDLGGPLPGYSMFVLDQKLE
CCCCCEEHHHHHHHHEEEEECCCCCEEEEEHHHHHHHCCHHCCCCCCCCCEEEEEECCCC
PVPPGIIGEIYIAGNAVSRGYLNRSTTTAERFFRNPFGEGRLYRTGDLARHFPSGELEYL
CCCCCCEEEEEEECCCHHCCCCCCCCHHHHHHHHCCCCCCCEEECCHHHHHCCCCCEEEC
GRNDFQVKIRGFRIELGEVESTIADVNGVTGVFVTVIDEPSGKTLVAWFTTNPEGPEATS
CCCCEEEEEEEEEEEECHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHH
LRKTISEQLTHYMVPTYLIKVDTFPVNISGKIDRSRLPMPENIKSEHESEPLTGLESKVQ
HHHHHHHHHHHHCCCEEEEEEECEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHH
LIWSEILEIPKERIKLDSNFFHLGGHSLNAAIACHKIAAELEQGLSPKTLFENPVLKDFS
HHHHHHHHCCHHHHEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHH
GCLSNQSKTNQLEPLIATGLTKTRMPGALLEMMLHRSIQNGQDTAYTIVVDIDFESDINP
HHHCCCCCCCCCCHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCH
LKLRAAFSELLAGDPIFSSHFLEQEGKTYIKHDPTTAIIIPLLTDTEKQTRINEFRGTSF
HHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCEEEEEEEECCCCHHHHHHHHCCCCH
DLLKAPLWRAEIIINERQSHLLLAINHGIFDGWSLTLMLRELAERYEASVSSDTYNRTAP
HHHHCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TMLDYGAWLSSHKEMRDASISYWDKKLSGGSCKTNLPGSSHPGAASLNLEKPINLPYLAT
CHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEE
CELKELATDLDVTLPPVLFAAYLVWLWRISGQDNLTVGYPYAGRDVLNSERVFGMFVQMG
CCHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHCCCHHHHHHHHHCC
FLRIDIDPEEQFTSLIKRVAKQMIEDRDHLLASPYDAEISSAGAPNILFSLQSGIGLEGT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
HGTVKFKAHEHPSQASKADIAAILYENSNGELQGRIEYDSAVMEEAEIEPLFECFNHLLN
CCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHH
SLAKYAKREISDLPYLSPKQVSQLIEFSGEVGDFREDNTTLINSLRQVIADHPEEIAIES
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECC
NHEQISYAELDQITNKLAKRIIFEGEPGSEKLIALSGIKSSSLVMATIAILKAGCAYVPI
CCCCCHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEC
DPNYPAERIEYILKDANIQLMLADADANSVINKISHQQLTLIDPQQVVGKEVDLGTTDLQ
CCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEEEEECHHHHHCCCCCCCCCCCC
DINDVEPRSLAYVIYTSGSTGKPKGVMVEHRTIPRMIDAAAELMNFTSSDRMLLLGTLNF
CCCCCCCCEEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
DASVLQMFTPLLKGGTLIIPPADAERDPDGLHQLINDKGVTHLVGTPALLRNLPREPLSK
CHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHCCCCCHHHH
LRFMGFGGEAIDTSTASFWAEKTCLYSLYGPTETTVMCSGGRILPGANPRIVGKPLMGYS
HHCCCCCCCCCCCCHHHHHHHCEEEEEEECCCCCEEEECCCEECCCCCCCEECCCCCCCE
INLRDQQLQPVPLGAIGELVISGGTARGYLNRYDLTLNRFRIDPDGVDPYQRVYLSGDLG
ECCCCCCCCCCCCCHHHHHEECCCCCCCCCEEEEEEEEEEEECCCCCCHHHEEEECCCHH
RFLPDGTIEFLGRNDDQIKLRGYRIELGEIEASMQSAPGVTNATAMVRGENDNRMLIGYL
HHCCCCCEEECCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEE
TGNEGLDIDEVRQHCQEQLPGYMVPSRFIKLENMPLNPNGKLDRNALPDVSFVSTSEPPK
ECCCCCCHHHHHHHHHHHCCCEECCCHHEEEECCCCCCCCCCCCCCCCCCEEECCCCCCC
VGLEQKVAAVWQDLLHLKNIGRKDDFFHLGGNSLLAARLQTLLRERCDLEISTANLYAHP
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEECEEEECC
TIAGLTGEKKVSEINQAINTATVSIQINQPVAPRSKFKKQPNVLLTGASGFLGVYLLAEL
EEECCCCCHHHHHHHHHHCEEEEEEEECCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHH
QSRAGEIICLARGKSDQQITDNLKKHAERSNLEIDFNQIRVIRGDLSKKGLGLRAYKYDQ
HHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEHHHEEEEECCCCCCCCCEEEEHHHH
LTNVVDQIIHCGAWINHLYSYSSLRSANVGSTVELIKLALAGKYRTPLCFISTESAATNL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHCCC
RGISCVEEAILDPVKNQPISDNGYMLSKWVSELILANAVHNHGLDCLIARPGNITGDSRT
CHHHHHHHHHHCHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
GFSNYSNNHFWMYTKGCLQMGMAPLIQQHVEMTPVDVLARAIVALVFDAQEGLRVANLSN
CCCCCCCCEEEEEEHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCC
PINIPWEQFFKAITQITGQEIAMVEAKSWQTKLNEINTDNTLYMLRDLYSENITTASPKV
CCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
NRSSSQAVLNSLGVSIDSDPRMLAKLYVPYLIEQGFLIP
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SIVETASLHLYISYLTEQKNIMTMLTSRIGLPSNQNSVSKIGFSEARSLFISNPKGNLR
CCCEEEEEEEEEEEHHCCHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHEEEECCCCCEE
LRDFLLDTCKLNEYSNLHANYPISKIIDVIRLDQPNFSEFTNIGADYTYLPYNSLHLDGI
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEECCCCCEEHHHH
EAILRTSFSRRRPSKDVSFKLRINQHNKLAIRTRHPDLLPAIKQSLPILLHRLENLHDEL
HHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
DHNIGDLSWMDREQRKSILIQSATPKNKKIAVDFLDRLVNKTKENPNHLALKYKEKSLTY
CCCCCCCHHCCHHHHHCEEEECCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
KELMAAADTLALRLRQLIKESNSSEPLFGICLPRGCEMIIALVGILRSGAGYLPLDPTNP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCC
RDRIDYILKDAKPVGVIIDDTTISIVEAVVNIKKVRIPTEENWREILNEPIANTLSESEA
HHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCE
IAYIIYTSGTTGLPKGVVIERGNLAAFISAAEEIASGEPGQRWQQFASINFDASILEISS
EEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHH
ALARGSTLVIAPSEIRSNPEALFEFLEQEGITHAFIPPAMLRLLPRRKLPALTDIYVGGE
HHHCCCEEEEECHHHCCCHHHHHHHHHHCCCEEECCCHHHHHHCCCCCCCCCEEEEECCC
ASDDLTVSFWSRATRLWNVYGPTETTVICSAKLMTSQLSATDLGGPLPGYSMFVLDQKLE
CCCCCEEHHHHHHHHEEEEECCCCCEEEEEHHHHHHHCCHHCCCCCCCCCEEEEEECCCC
PVPPGIIGEIYIAGNAVSRGYLNRSTTTAERFFRNPFGEGRLYRTGDLARHFPSGELEYL
CCCCCCEEEEEEECCCHHCCCCCCCCHHHHHHHHCCCCCCCEEECCHHHHHCCCCCEEEC
GRNDFQVKIRGFRIELGEVESTIADVNGVTGVFVTVIDEPSGKTLVAWFTTNPEGPEATS
CCCCEEEEEEEEEEEECHHHHHHHHCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCHHH
LRKTISEQLTHYMVPTYLIKVDTFPVNISGKIDRSRLPMPENIKSEHESEPLTGLESKVQ
HHHHHHHHHHHHCCCEEEEEEECEEEEECCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHH
LIWSEILEIPKERIKLDSNFFHLGGHSLNAAIACHKIAAELEQGLSPKTLFENPVLKDFS
HHHHHHHHCCHHHHEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHH
GCLSNQSKTNQLEPLIATGLTKTRMPGALLEMMLHRSIQNGQDTAYTIVVDIDFESDINP
HHHCCCCCCCCCCHHHHHCCCHHCCCHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCH
LKLRAAFSELLAGDPIFSSHFLEQEGKTYIKHDPTTAIIIPLLTDTEKQTRINEFRGTSF
HHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEECCCEEEEEEEECCCCHHHHHHHHCCCCH
DLLKAPLWRAEIIINERQSHLLLAINHGIFDGWSLTLMLRELAERYEASVSSDTYNRTAP
HHHHCCCCEEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
TMLDYGAWLSSHKEMRDASISYWDKKLSGGSCKTNLPGSSHPGAASLNLEKPINLPYLAT
CHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEE
CELKELATDLDVTLPPVLFAAYLVWLWRISGQDNLTVGYPYAGRDVLNSERVFGMFVQMG
CCHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCCEEEECCCCCCHHCCCHHHHHHHHHCC
FLRIDIDPEEQFTSLIKRVAKQMIEDRDHLLASPYDAEISSAGAPNILFSLQSGIGLEGT
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
HGTVKFKAHEHPSQASKADIAAILYENSNGELQGRIEYDSAVMEEAEIEPLFECFNHLLN
CCEEEEEECCCCCCCCCCCEEEEEEECCCCCEEEEEEHHHHHHHHHCCCHHHHHHHHHHH
SLAKYAKREISDLPYLSPKQVSQLIEFSGEVGDFREDNTTLINSLRQVIADHPEEIAIES
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECC
NHEQISYAELDQITNKLAKRIIFEGEPGSEKLIALSGIKSSSLVMATIAILKAGCAYVPI
CCCCCHHHHHHHHHHHHHHHEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEC
DPNYPAERIEYILKDANIQLMLADADANSVINKISHQQLTLIDPQQVVGKEVDLGTTDLQ
CCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEEEEECHHHHHCCCCCCCCCCCC
DINDVEPRSLAYVIYTSGSTGKPKGVMVEHRTIPRMIDAAAELMNFTSSDRMLLLGTLNF
CCCCCCCCEEEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
DASVLQMFTPLLKGGTLIIPPADAERDPDGLHQLINDKGVTHLVGTPALLRNLPREPLSK
CHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCCEEECCCHHHHHCCCCCHHHH
LRFMGFGGEAIDTSTASFWAEKTCLYSLYGPTETTVMCSGGRILPGANPRIVGKPLMGYS
HHCCCCCCCCCCCCHHHHHHHCEEEEEEECCCCCEEEECCCEECCCCCCCEECCCCCCCE
INLRDQQLQPVPLGAIGELVISGGTARGYLNRYDLTLNRFRIDPDGVDPYQRVYLSGDLG
ECCCCCCCCCCCCCHHHHHEECCCCCCCCCEEEEEEEEEEEECCCCCCHHHEEEECCCHH
RFLPDGTIEFLGRNDDQIKLRGYRIELGEIEASMQSAPGVTNATAMVRGENDNRMLIGYL
HHCCCCCEEECCCCCCEEEEEEEEEEHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEE
TGNEGLDIDEVRQHCQEQLPGYMVPSRFIKLENMPLNPNGKLDRNALPDVSFVSTSEPPK
ECCCCCCHHHHHHHHHHHCCCEECCCHHEEEECCCCCCCCCCCCCCCCCCEEECCCCCCC
VGLEQKVAAVWQDLLHLKNIGRKDDFFHLGGNSLLAARLQTLLRERCDLEISTANLYAHP
CCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCEEEECEEEECC
TIAGLTGEKKVSEINQAINTATVSIQINQPVAPRSKFKKQPNVLLTGASGFLGVYLLAEL
EEECCCCCHHHHHHHHHHCEEEEEEEECCCCCCHHHHCCCCCEEEECCCHHHHHHHHHHH
QSRAGEIICLARGKSDQQITDNLKKHAERSNLEIDFNQIRVIRGDLSKKGLGLRAYKYDQ
HHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEHHHEEEEECCCCCCCCCEEEEHHHH
LTNVVDQIIHCGAWINHLYSYSSLRSANVGSTVELIKLALAGKYRTPLCFISTESAATNL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHCCC
RGISCVEEAILDPVKNQPISDNGYMLSKWVSELILANAVHNHGLDCLIARPGNITGDSRT
CHHHHHHHHHHCHHCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
GFSNYSNNHFWMYTKGCLQMGMAPLIQQHVEMTPVDVLARAIVALVFDAQEGLRVANLSN
CCCCCCCCEEEEEEHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCC
PINIPWEQFFKAITQITGQEIAMVEAKSWQTKLNEINTDNTLYMLRDLYSENITTASPKV
CCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCC
NRSSSQAVLNSLGVSIDSDPRMLAKLYVPYLIEQGFLIP
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA