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The map label for this gene is clpC [H]

Identifier: 124022698

GI number: 124022698

Start: 901643

End: 904222

Strand: Reverse

Name: clpC [H]

Synonym: P9303_09911

Alternate gene names: 124022698

Gene position: 904222-901643 (Counterclockwise)

Preceding gene: 124022699

Following gene: 124022697

Centisome position: 33.71

GC content: 51.01

Gene sequence:

>2580_bases
ATGTTCGAGCGGTTTACCGAGAAGGCCATCAAGGTGATAATGCTGGCCCAGGAAGAGGCCCGGCGCCTTGGTCATAATTT
CGTGGGCACCGAGCAGATTCTTTTGGGATTGATCGGTGAGGGCACAGGTGTGGCAGCGAAGGTTCTCAAGTCAATGAGCG
TGAACCTTAAAGACGCCCGCGTTGAAGTCGAAAAGATCATTGGCCGTGGTTCAGGCTTCGTCGCCGTAGAAATCCCCTTC
ACACCCAGAGCAAAGCGCGTACTGGAACTCTCTCTAGAAGAAGCCCGACAACTTGGCCACAATTACATCGGCACAGAACA
TTTACTGCTTGGTCTCATCCGAGAAGGTGAGGGTGTAGCAGCCCGAGTACTCGAAAACCTTGGTGTAGACCTAGCAAAGG
TGCGCACCCAAGTAATCCGCATGCTCGGAGAAACCGCCGAGGTCACTGCAGGCGGAGGTGGAGGCAAAGGCTCAACGAAG
ACAGCCACACTTGATGAATTCGGCAGCAACCTGACCCAGCTAGCCAATGAATCCAAGCTTGATCCTGTTGTCGGGCGACA
AAATGAAATCGATCGTGTTATTCAGATCCTCGGAAGACGCACAAAGAACAACCCTGTACTGATTGGAGAGCCTGGAGTTG
GAAAAACAGCAATTGCTGAAGGCCTCGCTCAACGCATCCAACAGGGAGATATTCCCGACATCCTTGAAGAGAAGAGGGTT
CTAACCCTCGACATCGGCCTGCTAGTTGCTGGAACCAAATATCGAGGAGAGTTCGAAGAACGGCTCAAAAAGATCATGGA
AGAGATCAAGTCCGCAGGCAACGTGATCCTGGTCATCGATGAAGTGCACACACTGATTGGAGCAGGCGCTGCAGAAGGTG
CAATCGATGCCGCCAACATTCTCAAACCAGCGCTAGCTAGAGGAGAACTGCAGTGCATTGGTGCCACCACTCTTGACGAA
TATCGAAAACACATCGAACGGGATGCTGCCCTAGAACGCCGATTTCAGCCGGTCATGGTTGGCGAGCCATCGATCGCTGA
AACCATTGAGATCCTGCAAGGATTAAGGGAGCGCTACGAACAGCATCACCGCCTAAAAATCACAGACGAAGCCCTAGATG
CCGCCGCAAACCTAGGTGATCGCTATATCTCTGACCGCTTCCTGCCGGATAAGGCCATCGACTTAATCGATGAAGCTGGC
AGCCGTGTGCGTTTACTTAACTCCAAACTTCCCCCTGCGGCAAAAGAGGTCGACAAAGAATTACGCAAGGTTCAAAAGGA
AAAAGAAGATGCCGTTCGTGATCAGGACTTCGCCAAAGCCGGGGAATTACGTGAAAAAGAAGTTGAGCTAAGAGAAAAGA
TCCGCACTCTGCTTCAAAGCAGTCGCCAAGACAGCGAGGAATCGCCCCCCGCTGAAGCAGAAAATGCTGTTCGTTCCAGC
GATGAGACTCCAACGCCTCAACCTGAAAAAGACACAACAGCTCCATCAATTCCTCCTCTCACCACACCACTGGTGACAGA
AGAAGATATTGCCAACATCGTTGCGGCTTGGACCGGAGTACCTGTACAAAAGCTCACCGAAAGCGAATCAGTGAAGCTCC
TAAACATGGAGGAAACCCTCCACCAGAGGCTGATTGGCCAAGATGAAGCCGTCAAAGCAGTCTCGAAAGCCATCCGTCGA
GCCAGGGTGGGCCTCAAAAACCCCAATCGCCCCATTGCCAGTTTCATCTTTTCAGGCCCTACGGGCGTCGGCAAAACCGA
ACTAACCAAAGCTCTCGCCACCTACTTCTTTGGTAGCGAAGAAGCCATGATCCGACTAGACATGTCGGAATTCATGGAGC
GACATACGGTCAGCAAGCTGATCGGATCACCTCCTGGCTATGTGGGGTTCAACGAAGGGGGACAACTCACCGAAGCTGTT
CGTCGCAGACCTTATACCGTTGTGCTCTTCGACGAAATCGAGAAGGCACACCCAGATGTTTTTAACCTGCTGCTTCAATT
ATTGGAAGATGGTCGACTAACTGACTCCAAAGGAAGAACAGTGGACTTCAAGAACACCTTGATCATTATGACTTCGAATA
TCGGTTCAAAAGTGATTGAGAAAGGAGGCGGAGGACTTGGCTTCGAATTCTCAGGTGAAAATGCAGAAGAAAGTCAATAC
AACCGGATCAAATCCCTGGTCAACGAAGAACTAAAACAATACTTCCGTCCTGAATTTCTCAACCGTCTCGATGAAATTAT
CGTCTTCCGCCAACTCAGCAGAGATGAGGTGAAAGAAATCGCTGAGATCATGCTTAAAGAAGTGTTCTCTCGCATGCAAG
ACAAAGGGATCACTCTCACTGTTTCAGATGCATTCAAAGAGCGACTAGTGGAAGAGGGATACAACCCCTCTTATGGAGCG
AGGCCGCTGCGAAGGGCTGTCATGCGGCTCATGGAAGACAGTCTTGCCGAGGAAGTGCTTACTGGCCGCATCAAGGACGG
TGATGCTGCGGAAATGGACGTAGATGACAACAAGCAAATCGTTGTCCGCCATGTCAGCAAAACTACTGCCACACCGGAAC
TCGCTGGAGCAGGCGTCTGA

Upstream 100 bases:

>100_bases
CTAACTCCCTTGCAGTAAAGGGACTAGGCCAAATAATCCAACAGCTCACATTCCAACACTAACCCTGATAAGTTAGAGAT
AGATTCACGTGCCCCGGACC

Downstream 100 bases:

>100_bases
CACCTCTCCAACATCAATGAACAAAAACAATTTGCCTGAGGAGGTCTCTCACTGCTCTCACTCCATCGCCCCCGCAAAGG
TTGTTAGGGGAGAAAGGGCT

Product: ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 859; Mature: 859

Protein sequence:

>859_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDARVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTK
TATLDEFGSNLTQLANESKLDPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPAAKEVDKELRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQDSEESPPAEAENAVRSS
DETPTPQPEKDTTAPSIPPLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETLHQRLIGQDEAVKAVSKAIRR
ARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAV
RRRPYTVVLFDEIEKAHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEESQY
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKEIAEIMLKEVFSRMQDKGITLTVSDAFKERLVEEGYNPSYGA
RPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQIVVRHVSKTTATPELAGAGV

Sequences:

>Translated_859_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDARVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTK
TATLDEFGSNLTQLANESKLDPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPAAKEVDKELRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQDSEESPPAEAENAVRSS
DETPTPQPEKDTTAPSIPPLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETLHQRLIGQDEAVKAVSKAIRR
ARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAV
RRRPYTVVLFDEIEKAHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEESQY
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKEIAEIMLKEVFSRMQDKGITLTVSDAFKERLVEEGYNPSYGA
RPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQIVVRHVSKTTATPELAGAGV
>Mature_859_residues
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDARVEVEKIIGRGSGFVAVEIPF
TPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVAARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTK
TATLDEFGSNLTQLANESKLDPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDE
YRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYEQHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAG
SRVRLLNSKLPPAAKEVDKELRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQDSEESPPAEAENAVRSS
DETPTPQPEKDTTAPSIPPLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETLHQRLIGQDEAVKAVSKAIRR
ARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAV
RRRPYTVVLFDEIEKAHPDVFNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEESQY
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKEIAEIMLKEVFSRMQDKGITLTVSDAFKERLVEEGYNPSYGA
RPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQIVVRHVSKTTATPELAGAGV

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=325, Percent_Identity=39.6923076923077, Blast_Score=207, Evalue=3e-53,
Organism=Escherichia coli, GI1788943, Length=885, Percent_Identity=46.2146892655367, Blast_Score=747, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=414, Percent_Identity=40.5797101449275, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6320464, Length=710, Percent_Identity=48.5915492957746, Blast_Score=642, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=871, Percent_Identity=37.5430539609644, Blast_Score=545, Evalue=1e-155,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 94835; Mature: 94835

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
VEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTKTATLDEFGSNLTQLANESKL
HHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
DPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAGSRVRLLNSKLPPAAKEVDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEHHCCCCCHHHHHHHH
LRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQDSEESPPAEAENAVRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
DETPTPQPEKDTTAPSIPPLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCEEEECHHHHH
HQRLIGQDEAVKAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSE
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
EAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEIEKAHPDV
CCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHH
FNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEESQY
HHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEEECCCCCCHHHH
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKEIAEIMLKEVFSRMQDKGITLT
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEE
VSDAFKERLVEEGYNPSYGARPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQI
EHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
VVRHVSKTTATPELAGAGV
EEEEHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGVAAKVLKSMSVNLKDAR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHH
VEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGTEHLLLGLIREGEGVA
HHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHH
ARVLENLGVDLAKVRTQVIRMLGETAEVTAGGGGGKGSTKTATLDEFGSNLTQLANESKL
HHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
DPVVGRQNEIDRVIQILGRRTKNNPVLIGEPGVGKTAIAEGLAQRIQQGDIPDILEEKRV
CCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
LTLDIGLLVAGTKYRGEFEERLKKIMEEIKSAGNVILVIDEVHTLIGAGAAEGAIDAANI
EEEEEHHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCCHHHHH
LKPALARGELQCIGATTLDEYRKHIERDAALERRFQPVMVGEPSIAETIEILQGLRERYE
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
QHHRLKITDEALDAAANLGDRYISDRFLPDKAIDLIDEAGSRVRLLNSKLPPAAKEVDKE
HHCCEEECHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEHHCCCCCHHHHHHHH
LRKVQKEKEDAVRDQDFAKAGELREKEVELREKIRTLLQSSRQDSEESPPAEAENAVRSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCC
DETPTPQPEKDTTAPSIPPLTTPLVTEEDIANIVAAWTGVPVQKLTESESVKLLNMEETL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCEEEECHHHHH
HQRLIGQDEAVKAVSKAIRRARVGLKNPNRPIASFIFSGPTGVGKTELTKALATYFFGSE
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
EAMIRLDMSEFMERHTVSKLIGSPPGYVGFNEGGQLTEAVRRRPYTVVLFDEIEKAHPDV
CCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEHHHHHHCCHH
FNLLLQLLEDGRLTDSKGRTVDFKNTLIIMTSNIGSKVIEKGGGGLGFEFSGENAEESQY
HHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCCCHHHHHCCCCCCCEEECCCCCCHHHH
NRIKSLVNEELKQYFRPEFLNRLDEIIVFRQLSRDEVKEIAEIMLKEVFSRMQDKGITLT
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEE
VSDAFKERLVEEGYNPSYGARPLRRAVMRLMEDSLAEEVLTGRIKDGDAAEMDVDDNKQI
EHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
VVRHVSKTTATPELAGAGV
EEEEHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]