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The map label for this gene is msrR [H]

Identifier: 124022685

GI number: 124022685

Start: 888886

End: 889896

Strand: Reverse

Name: msrR [H]

Synonym: P9303_09781

Alternate gene names: 124022685

Gene position: 889896-888886 (Counterclockwise)

Preceding gene: 124022687

Following gene: 124022683

Centisome position: 33.17

GC content: 54.5

Gene sequence:

>1011_bases
TTGAGCAAGACTGTGATACCGCTGTCCTCAACACGGTTGATGCCTACACAAGATTCAGGCAGAACGCCATCGAGCGTTGG
TCGCTGGATGGGGAAATATCCAGGCCGTACCTTGCTACGCCTGGCTGCGATCCTGGGTGGTCTTTGGCTGGCAAGCACGG
CCCTCGGGCTGCTCTGGCCGAAGCCAGATCAAGTCGCCAAAGGCGATCCATCAGTGGACAAAGCAACCTCCCTAGCGCCG
CTTCCCAAACAACCAATCATCATCTTGTTAGTGGGCATTGATTCGGACCAACTGAACGATCTCACAAACAAAGCGGCACC
GATGGGTTCAGCCAATGCAGACAGCCTGATGCTCGTGAAGGTTGCGGCCAAGCAACCTGTTGAAGTTCTTCAGCTGCCGA
TTGAACTCGCTGTGACCCTGCCTGGAAGCAATGAGATGCAACCACTAGCGTCAAGTTACGGGCGGGGGGGTATTGCCCTT
ACCGCCGATGTGATTGCGGAAATCCTCGGCCTTACAAAAGGACAACCCCACCGCTTTGTGGTGATCCCCCGCAAAGCTCT
AAGAGTCCTTGTAGATGGACTCGGAGATGTGGAGGTCAACCTCAACGCGCCTATTAAACACAAAGACAATGCCCAGAACT
ATTCGGTGGACTTGCAAGCAGGGCGGCAGAGACTCAATGGAGGCGAGGTAGAACAACTGGTTCGCTACCGCGCAGGTCCT
GAAGAAGAAAGCGGTCGGCGTCAAAGGCAACAATGGATCCTGAACGGTCTGTCTAGACAATTGCGGCAGCCGAACACCCT
CGCAAAACTCCCCAAACTTCTGAAAGAGTTTTCAAAAGAAGTACAAACCGATTTAACCCCTCGTGAGTTGTTAAGCCTCA
CGGCAGCGGCTCTTAGCAACAATCAATTCCCAATCCTCAGCGAGTTACCTCTAGCCCCAAGAGCCGGGGAACAAACCCTG
CGGCAACTCAAGGCAAGCCACCCCATGCCGCTCTGGCCGCAGGGCAACTAA

Upstream 100 bases:

>100_bases
GGAAGGACTTAGGCCGGGTCGTTACATACTCGCAAGATGCCTTGCCAGAAGTCTCGGTTCGTCCAAAAGCCATTGGACTT
TTAACCCTAAGGAGCTGTAG

Downstream 100 bases:

>100_bases
CAGGGCCTCATCAATCGAACGACAGCAGCAGCCGTCGACGCAATTGCACCACGACCTCCTCCAAAGAGGGCCCCTGCTGC
AAGCAGCCCCCATTAGGGAC

Product: LytR-membrane bound transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSKTVIPLSSTRLMPTQDSGRTPSSVGRWMGKYPGRTLLRLAAILGGLWLASTALGLLWPKPDQVAKGDPSVDKATSLAP
LPKQPIIILLVGIDSDQLNDLTNKAAPMGSANADSLMLVKVAAKQPVEVLQLPIELAVTLPGSNEMQPLASSYGRGGIAL
TADVIAEILGLTKGQPHRFVVIPRKALRVLVDGLGDVEVNLNAPIKHKDNAQNYSVDLQAGRQRLNGGEVEQLVRYRAGP
EEESGRRQRQQWILNGLSRQLRQPNTLAKLPKLLKEFSKEVQTDLTPRELLSLTAAALSNNQFPILSELPLAPRAGEQTL
RQLKASHPMPLWPQGN

Sequences:

>Translated_336_residues
MSKTVIPLSSTRLMPTQDSGRTPSSVGRWMGKYPGRTLLRLAAILGGLWLASTALGLLWPKPDQVAKGDPSVDKATSLAP
LPKQPIIILLVGIDSDQLNDLTNKAAPMGSANADSLMLVKVAAKQPVEVLQLPIELAVTLPGSNEMQPLASSYGRGGIAL
TADVIAEILGLTKGQPHRFVVIPRKALRVLVDGLGDVEVNLNAPIKHKDNAQNYSVDLQAGRQRLNGGEVEQLVRYRAGP
EEESGRRQRQQWILNGLSRQLRQPNTLAKLPKLLKEFSKEVQTDLTPRELLSLTAAALSNNQFPILSELPLAPRAGEQTL
RQLKASHPMPLWPQGN
>Mature_335_residues
SKTVIPLSSTRLMPTQDSGRTPSSVGRWMGKYPGRTLLRLAAILGGLWLASTALGLLWPKPDQVAKGDPSVDKATSLAPL
PKQPIIILLVGIDSDQLNDLTNKAAPMGSANADSLMLVKVAAKQPVEVLQLPIELAVTLPGSNEMQPLASSYGRGGIALT
ADVIAEILGLTKGQPHRFVVIPRKALRVLVDGLGDVEVNLNAPIKHKDNAQNYSVDLQAGRQRLNGGEVEQLVRYRAGPE
EESGRRQRQQWILNGLSRQLRQPNTLAKLPKLLKEFSKEVQTDLTPRELLSLTAAALSNNQFPILSELPLAPRAGEQTLR
QLKASHPMPLWPQGN

Specific function: Involved in sarA attenuation. Affects resistance to oxacillin and teicoplanin, as well as the synthesis of virulence factors [H]

COG id: COG1316

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LytR/CpsA/Psr regulatory protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004474 [H]

Pfam domain/function: PF03816 LytR_cpsA_psr [H]

EC number: NA

Molecular weight: Translated: 36431; Mature: 36300

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTVIPLSSTRLMPTQDSGRTPSSVGRWMGKYPGRTLLRLAAILGGLWLASTALGLLWP
CCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
KPDQVAKGDPSVDKATSLAPLPKQPIIILLVGIDSDQLNDLTNKAAPMGSANADSLMLVK
CCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEEE
VAAKQPVEVLQLPIELAVTLPGSNEMQPLASSYGRGGIALTADVIAEILGLTKGQPHRFV
ECCCCCHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCEEE
VIPRKALRVLVDGLGDVEVNLNAPIKHKDNAQNYSVDLQAGRQRLNGGEVEQLVRYRAGP
EECHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHCCCC
EEESGRRQRQQWILNGLSRQLRQPNTLAKLPKLLKEFSKEVQTDLTPRELLSLTAAALSN
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
NQFPILSELPLAPRAGEQTLRQLKASHPMPLWPQGN
CCCCCHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SKTVIPLSSTRLMPTQDSGRTPSSVGRWMGKYPGRTLLRLAAILGGLWLASTALGLLWP
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
KPDQVAKGDPSVDKATSLAPLPKQPIIILLVGIDSDQLNDLTNKAAPMGSANADSLMLVK
CCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCCCEEEEE
VAAKQPVEVLQLPIELAVTLPGSNEMQPLASSYGRGGIALTADVIAEILGLTKGQPHRFV
ECCCCCHHHHHCCEEEEEECCCCCCCCHHHHHCCCCCEEEHHHHHHHHHHCCCCCCCEEE
VIPRKALRVLVDGLGDVEVNLNAPIKHKDNAQNYSVDLQAGRQRLNGGEVEQLVRYRAGP
EECHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHCCCC
EEESGRRQRQQWILNGLSRQLRQPNTLAKLPKLLKEFSKEVQTDLTPRELLSLTAAALSN
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
NQFPILSELPLAPRAGEQTLRQLKASHPMPLWPQGN
CCCCCHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12878519 [H]