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The map label for this gene is pntA-2 [H]

Identifier: 124022570

GI number: 124022570

Start: 778788

End: 779093

Strand: Direct

Name: pntA-2 [H]

Synonym: P9303_08611

Alternate gene names: 124022570

Gene position: 778788-779093 (Clockwise)

Preceding gene: 124022569

Following gene: 124022571

Centisome position: 29.03

GC content: 55.88

Gene sequence:

>306_bases
ATGTCGTTCTTGAGTGAGGCCCTTTGGGTGCTGCTGCTTGGCAGCTTGCTTGGCCTTGAACTGATCGGCAAGGTGCCTCC
CACTTTGCATACGCCTTTGATGAGTGGTGCCAATGCGATCTCGGGGATCACGATGTTGGCCGCTCTCACCCTGATCATCA
AGGCCGGTAACAACATCCCTCTGCTGGCGATGGGTGCTGTTGCTCTTGGTTTCGCCTTGTTCAACGTGATTGGCGGATTT
CTCGTTACCGATCGGATGCTGGCCATGTTCAGCCGCAAGTCATCTCGCCGCAGGGACAACCACTGA

Upstream 100 bases:

>100_bases
TCAGTTTGAACATTGAGGATGAGTTAATTGCCGGATGCCTGATCAGTCACAACGGTGTTATTCGCCATGACGATGTGCTT
AACACAGGAGGGTCCAACTG

Downstream 100 bases:

>100_bases
TGAATATTGCTGAGATCCTTAAGTTCGCGATTGATCTGGTCGCGGTTTTACTGCTTGCCCTTGGGATCAAGGGCCTTTCG
AAGGTGCGCTCTGCTCGTGA

Product: nicotinamide nucleotide transhydrogenase, subunit alpha 2 (A2)

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha; Pyridine nucleotide transhydrogenase subunit alpha [H]

Number of amino acids: Translated: 101; Mature: 100

Protein sequence:

>101_residues
MSFLSEALWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIIKAGNNIPLLAMGAVALGFALFNVIGGF
LVTDRMLAMFSRKSSRRRDNH

Sequences:

>Translated_101_residues
MSFLSEALWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIIKAGNNIPLLAMGAVALGFALFNVIGGF
LVTDRMLAMFSRKSSRRRDNH
>Mature_100_residues
SFLSEALWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIIKAGNNIPLLAMGAVALGFALFNVIGGFL
VTDRMLAMFSRKSSRRRDNH

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR016040
- InterPro:   IPR004571 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 10720; Mature: 10589

Theoretical pI: Translated: 11.52; Mature: 11.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLSEALWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIIKAGNNIP
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
LLAMGAVALGFALFNVIGGFLVTDRMLAMFSRKSSRRRDNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFLSEALWVLLLGSLLGLELIGKVPPTLHTPLMSGANAISGITMLAALTLIIKAGNNIP
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCC
LLAMGAVALGFALFNVIGGFLVTDRMLAMFSRKSSRRRDNH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]