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The map label for this gene is 124022566

Identifier: 124022566

GI number: 124022566

Start: 775214

End: 776530

Strand: Reverse

Name: 124022566

Synonym: P9303_08571

Alternate gene names: NA

Gene position: 776530-775214 (Counterclockwise)

Preceding gene: 124022568

Following gene: 124022565

Centisome position: 28.95

GC content: 56.72

Gene sequence:

>1317_bases
GTGCTTGTGCATGCTGGCCCAGGTGCAGGCAAAACCCTCGGCGCCCTCCTCAGCTTCGAGGCCATGCAGCGAGGGGGGGG
CTTAACGCGATTCATAGTTTTTTGCCACCGCAACTCGATCCTGAATCAATGGCACCAAGCATCTAAACAACTAGGACTCA
ACTTGCAGGACTGGGAAGCTTGCCCAGAACAACCCGAGATCCTCAAACAAGCAGACGGCTGGGCAGTGACCTATCAAGGT
GCCGGTCTTCAGTTAGAGACCCTGATAGCAGAACTAAAAGACTGGGCCGGTGACGGCTTACTCGCTATTGCCGATGAAGC
CCACCACCTCGGGATGAATCCAGATGAACCTCAGGGCCCAGCCTGGGGACGAACCTTTCTTGCTCTCACTGGCAGCAGCA
AAATACGGCTTGGTCTTACTGGCACGCCCTTCCGCGCCGACAATCTGGCCTTCTGTGCAGCCCGACGGGTGCGCGTGGAA
GCCGAGGGAGCTCTGGTGGAGCAGATCAGCCCAGATCTCTGCGTGGAACCTAGTGAGCTGATTCATTCTGGAGATGTGCG
CCCACTCGAATTCCGCTTCCAGGACGGCTGGGTGGAACACAGCCGTCCTGGACAGCCCGATCGAGATGTCTCCCCCCTCT
CTGCTGAAGTGCGTGAAAGCTGGCGAGCACGCAATCTGCGTAGGGCTATTCGGATCTCAGACTCAAGCAGTATTGCCTTG
CAACTGTTACTACGGGCACGACGTCAACTTGAGAAGGTACGTCGCCACCATCACGATGCAGCAGGCCTTGTGATCGCTAG
AGATATCGAACACGCTGTTGGCATCGCCCAGCTCCTGCAAGAGGAAGGCGATCGTGTCGAGCTGGTGCACTCCCAAGACC
GTGATGCCAGTGCTCGCCTGGCAGCCTTCCAAACAAGCAAAGCCGACTGGTTAGTAAGCATCGACATGTGTGCCGAGGGA
TTCGATGCCCCAAGACTTCGCGTGGTTGCTTATCTCACAACGGTGGTAACGCGCAGCCGATTCATACAGGGAATCACTCG
CGCTGTAAGGATCTCCACAGCAAGAGCATCGTTAGAGCCGGTACCTCGTCACCCTTCCTATGTCTTTGCACCTGCAGATC
CCTTACTGATGGGCCATGCCCGAAGCTGGTCGAGGACAGAGCCATATCTCATCAGAGACAGCGAAGCGAAAGCAGAGGGA
AACACAACGATGGGTCACTGGCGAGGCCCAAGCCTGCCACTCGAAGCAGTCAACGATGGAGCAGGTGCTGTCATCCGACT
ACGCACACCAAATCTGCCCAGTTTTTTGCAGCGTTGA

Upstream 100 bases:

>100_bases
AGAGTCCCGCCAGCCCAAAATCCGACCCCGCATTTGGCAGCAACAGCTGATTCAGCTGCTGCGTCGCAGACTGTCTCCAC
AGGCAATCCAAGGGCGAGAT

Downstream 100 bases:

>100_bases
CGACAACTTTTCCGAAAGAAAAATGCGACGTTCTATAAAATCAAACCAAATACAGACCACTTACATGCAATTCTCTGGCC
AATGGGGACCAATCATGAAC

Product: helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MLVHAGPGAGKTLGALLSFEAMQRGGGLTRFIVFCHRNSILNQWHQASKQLGLNLQDWEACPEQPEILKQADGWAVTYQG
AGLQLETLIAELKDWAGDGLLAIADEAHHLGMNPDEPQGPAWGRTFLALTGSSKIRLGLTGTPFRADNLAFCAARRVRVE
AEGALVEQISPDLCVEPSELIHSGDVRPLEFRFQDGWVEHSRPGQPDRDVSPLSAEVRESWRARNLRRAIRISDSSSIAL
QLLLRARRQLEKVRRHHHDAAGLVIARDIEHAVGIAQLLQEEGDRVELVHSQDRDASARLAAFQTSKADWLVSIDMCAEG
FDAPRLRVVAYLTTVVTRSRFIQGITRAVRISTARASLEPVPRHPSYVFAPADPLLMGHARSWSRTEPYLIRDSEAKAEG
NTTMGHWRGPSLPLEAVNDGAGAVIRLRTPNLPSFLQR

Sequences:

>Translated_438_residues
MLVHAGPGAGKTLGALLSFEAMQRGGGLTRFIVFCHRNSILNQWHQASKQLGLNLQDWEACPEQPEILKQADGWAVTYQG
AGLQLETLIAELKDWAGDGLLAIADEAHHLGMNPDEPQGPAWGRTFLALTGSSKIRLGLTGTPFRADNLAFCAARRVRVE
AEGALVEQISPDLCVEPSELIHSGDVRPLEFRFQDGWVEHSRPGQPDRDVSPLSAEVRESWRARNLRRAIRISDSSSIAL
QLLLRARRQLEKVRRHHHDAAGLVIARDIEHAVGIAQLLQEEGDRVELVHSQDRDASARLAAFQTSKADWLVSIDMCAEG
FDAPRLRVVAYLTTVVTRSRFIQGITRAVRISTARASLEPVPRHPSYVFAPADPLLMGHARSWSRTEPYLIRDSEAKAEG
NTTMGHWRGPSLPLEAVNDGAGAVIRLRTPNLPSFLQR
>Mature_438_residues
MLVHAGPGAGKTLGALLSFEAMQRGGGLTRFIVFCHRNSILNQWHQASKQLGLNLQDWEACPEQPEILKQADGWAVTYQG
AGLQLETLIAELKDWAGDGLLAIADEAHHLGMNPDEPQGPAWGRTFLALTGSSKIRLGLTGTPFRADNLAFCAARRVRVE
AEGALVEQISPDLCVEPSELIHSGDVRPLEFRFQDGWVEHSRPGQPDRDVSPLSAEVRESWRARNLRRAIRISDSSSIAL
QLLLRARRQLEKVRRHHHDAAGLVIARDIEHAVGIAQLLQEEGDRVELVHSQDRDASARLAAFQTSKADWLVSIDMCAEG
FDAPRLRVVAYLTTVVTRSRFIQGITRAVRISTARASLEPVPRHPSYVFAPADPLLMGHARSWSRTEPYLIRDSEAKAEG
NTTMGHWRGPSLPLEAVNDGAGAVIRLRTPNLPSFLQR

Specific function: Unknown

COG id: COG1061

COG function: function code KL; DNA or RNA helicases of superfamily II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis Rv2917 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: NA

Molecular weight: Translated: 48383; Mature: 48383

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVHAGPGAGKTLGALLSFEAMQRGGGLTRFIVFCHRNSILNQWHQASKQLGLNLQDWEA
CEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHC
CPEQPEILKQADGWAVTYQGAGLQLETLIAELKDWAGDGLLAIADEAHHLGMNPDEPQGP
CCCCHHHHHCCCCCEEEEECCCEEHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCC
AWGRTFLALTGSSKIRLGLTGTPFRADNLAFCAARRVRVEAEGALVEQISPDLCVEPSEL
CCCCEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHEEEECCCCHHHHCCCCCCCCHHHH
IHSGDVRPLEFRFQDGWVEHSRPGQPDRDVSPLSAEVRESWRARNLRRAIRISDSSSIAL
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHH
QLLLRARRQLEKVRRHHHDAAGLVIARDIEHAVGIAQLLQEEGDRVELVHSQDRDASARL
HHHHHHHHHHHHHHHHCCCHHCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHE
AAFQTSKADWLVSIDMCAEGFDAPRLRVVAYLTTVVTRSRFIQGITRAVRISTARASLEP
EEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPRHPSYVFAPADPLLMGHARSWSRTEPYLIRDSEAKAEGNTTMGHWRGPSLPLEAVNDG
CCCCCCEEECCCCCEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCC
AGAVIRLRTPNLPSFLQR
CCEEEEEECCCCHHHHCC
>Mature Secondary Structure
MLVHAGPGAGKTLGALLSFEAMQRGGGLTRFIVFCHRNSILNQWHQASKQLGLNLQDWEA
CEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCHHHHC
CPEQPEILKQADGWAVTYQGAGLQLETLIAELKDWAGDGLLAIADEAHHLGMNPDEPQGP
CCCCHHHHHCCCCCEEEEECCCEEHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCC
AWGRTFLALTGSSKIRLGLTGTPFRADNLAFCAARRVRVEAEGALVEQISPDLCVEPSEL
CCCCEEEEEECCCEEEEEECCCCCCCCCHHHHHHHHEEEECCCCHHHHCCCCCCCCHHHH
IHSGDVRPLEFRFQDGWVEHSRPGQPDRDVSPLSAEVRESWRARNLRRAIRISDSSSIAL
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCHHHHH
QLLLRARRQLEKVRRHHHDAAGLVIARDIEHAVGIAQLLQEEGDRVELVHSQDRDASARL
HHHHHHHHHHHHHHHHCCCHHCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHE
AAFQTSKADWLVSIDMCAEGFDAPRLRVVAYLTTVVTRSRFIQGITRAVRISTARASLEP
EEEECCCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VPRHPSYVFAPADPLLMGHARSWSRTEPYLIRDSEAKAEGNTTMGHWRGPSLPLEAVNDG
CCCCCCEEECCCCCEEECCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHCCCC
AGAVIRLRTPNLPSFLQR
CCEEEEEECCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]