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The map label for this gene is ubiE [C]

Identifier: 124022562

GI number: 124022562

Start: 772602

End: 773405

Strand: Direct

Name: ubiE [C]

Synonym: P9303_08531

Alternate gene names: 124022562

Gene position: 772602-773405 (Clockwise)

Preceding gene: 124022561

Following gene: 124022564

Centisome position: 28.8

GC content: 56.47

Gene sequence:

>804_bases
ATGAGCAGTAGCTGCTGTAGTCCCTCTGCTTCAGGCCCTGGAGCTGATGCGTTGGATCAGACGCAGGCTGTAGAGGAGCG
CTATGGAGCTGCAGCGCATGCCCAGGAAGCTTGTTTGTGTACCCCGGTGGCTTTCGATCTCAGCCTGCTTCAGGCCATCC
CTCGTGATGTTGTGGAGCGCGATTACGGCTGCGGTGACCCAACTCGCTGGGTTAAGCCTGGTGACACTGTGCTTGATCTT
GGCAGTGGCAGTGGCAAGAACGCCTTCATTTGTGCCCAGCTGATCGGTTCGGCGGGTGCCGTGATTGGGGTGGATCGCAA
TGTTGAGATGCTCAACCTGGCTCGTCAGGCCGCACCAGTTGTGGCGGAGCGGATTGGCTTTGCCAATGTGCGCTTTGTGG
AGGGCGCTATCGAAGCGCTTGAAGCCCCTCAGGTTGATGGAGCTCCGCTAATTGCCGATCGGTCGATTGATGTGGTGTTG
AGCAACTGTGTGCTCAATTTGGTGAATCCTGCAGATCGTCAGAATCTGCTGGCCAACATTCGCAGGGTTTTGCGGCCAGG
TGGACGGCTTGCTGTTAGCGATATCGTCTGTGATAAGCCAGTACCCCTTGCTCTTCAGCAGGATCCGGAACTTTGGAGTG
GCTGCATTAGTGGGGCCTGGCAGGAAGAGGCCTTCCTAGAGGATTTTCGTGCTTTGGGCTTTGAGAAGGTGAGCTATGCC
GATCGTTCTGATCAACCCTGGCAGGTGGTTGAAGACATTGAATTTCGCGCCGTCACGCTTGTGGGTCAGCTGCCGGACGA
TTGA

Upstream 100 bases:

>100_bases
CTGGAGGCCTTGGGCTAATGCCCTTGGGGCATGCAGGCTTAGCCACCGATTCTTTCCCTACCGACCACAATGGATTGGTC
TTTCTTGAAGGGCTTTTTTC

Downstream 100 bases:

>100_bases
GGAGGGACAGCAGGAGGTTGGTCTCTCTTGATGAGACCTGCCTCCATTGGCCAGGATCCAGCCCTTCAATGCTGAGGGGT
GGCTCACCATCCATAAGCTC

Product: methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Arsenite S-Adenosylmethyltransferase; Methyltransferase; Arsenite Methyltransferase; SAM-Dependent Methyltransferase; Methyltransferase Domain Family; Methyltransferase-Like; UbiE/COQ5 Methyltransferase; Arsenic Methyltransferase; 2-Heptaprenyl-1 4-Naphthoquinone Methyltransferase; ArsR Family Transcriptional Regulator; SAM-Dependent Methyltransferases; UbiE/COQ5 Family Methlytransferase; Cyclopropane-Fatty-Acyl-Phospholipid Synthase; Methyltransferase UbiE-Family; Radical SAM Domain-Containing Protein; Transcriptional Regulator ArsR Family

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLQAIPRDVVERDYGCGDPTRWVKPGDTVLDL
GSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPVVAERIGFANVRFVEGAIEALEAPQVDGAPLIADRSIDVVL
SNCVLNLVNPADRQNLLANIRRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLEDFRALGFEKVSYA
DRSDQPWQVVEDIEFRAVTLVGQLPDD

Sequences:

>Translated_267_residues
MSSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLQAIPRDVVERDYGCGDPTRWVKPGDTVLDL
GSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPVVAERIGFANVRFVEGAIEALEAPQVDGAPLIADRSIDVVL
SNCVLNLVNPADRQNLLANIRRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLEDFRALGFEKVSYA
DRSDQPWQVVEDIEFRAVTLVGQLPDD
>Mature_266_residues
SSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLQAIPRDVVERDYGCGDPTRWVKPGDTVLDLG
SGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPVVAERIGFANVRFVEGAIEALEAPQVDGAPLIADRSIDVVLS
NCVLNLVNPADRQNLLANIRRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLEDFRALGFEKVSYAD
RSDQPWQVVEDIEFRAVTLVGQLPDD

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109389364, Length=189, Percent_Identity=36.5079365079365, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28475; Mature: 28344

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLQAIPRDVVER
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHCHHHHHHHHHHHHHHHHHHH
DYGCGDPTRWVKPGDTVLDLGSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPV
CCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
VAERIGFANVRFVEGAIEALEAPQVDGAPLIADRSIDVVLSNCVLNLVNPADRQNLLANI
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
RRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLEDFRALGFEKVSYA
HHHHCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCC
DRSDQPWQVVEDIEFRAVTLVGQLPDD
CCCCCCHHHHHCCCEEEEEEEECCCCC
>Mature Secondary Structure 
SSSCCSPSASGPGADALDQTQAVEERYGAAAHAQEACLCTPVAFDLSLLQAIPRDVVER
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCHHHCHHHHHHHHHHHHHHHHHHH
DYGCGDPTRWVKPGDTVLDLGSGSGKNAFICAQLIGSAGAVIGVDRNVEMLNLARQAAPV
CCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHH
VAERIGFANVRFVEGAIEALEAPQVDGAPLIADRSIDVVLSNCVLNLVNPADRQNLLANI
HHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCHHHHHHHHH
RRVLRPGGRLAVSDIVCDKPVPLALQQDPELWSGCISGAWQEEAFLEDFRALGFEKVSYA
HHHHCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHCC
DRSDQPWQVVEDIEFRAVTLVGQLPDD
CCCCCCHHHHHCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA